Compounds > imidazole

imidazole and piperazine

imidazole has been researched along with piperazine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fotsch, C; St Jean, DJ1
Baryshnikova, OK; Sykes, BD; Williams, TC1
Frymarkiewicz, A; Walczyński, K1
Addla, D; Jallapally, A; Kantevari, S; Sriram, D; Yogeeswari, P1
Comery, TA; Doran, A; Gao, H; Lockwood, P; Mancuso, J; Obach, RS; Sawant-Basak, A; Schildknegt, K; Tse, S1
Bajda, M; Bednarski, M; Bucki, A; Czopek, A; Głuch-Lutwin, M; Jastrzębska-Więsek, M; Jończyk, J; Koczurkiewicz, P; Kołaczkowski, M; Partyka, A; Pawłowski, M; Piska, K; Siwek, A; Wesołowska, A; Zagórska, A1

Reviews

1 review(s) available for imidazole and piperazine

ArticleYear
Mitigating heterocycle metabolism in drug discovery.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats

2012

Other Studies

5 other study(ies) available for imidazole and piperazine

ArticleYear
Internal pH indicators for biomolecular NMR.
    Journal of biomolecular NMR, 2008, Volume: 41, Issue:1

    Topics: Buffers; Formates; Hydrogen-Ion Concentration; Imidazoles; Nuclear Magnetic Resonance, Biomolecular; Piperazine; Piperazines; Tromethamine

2008
Non-imidazole histamine H3 ligands, part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Animals; Guinea Pigs; Histamine H1 Antagonists; Histamine H3 Antagonists; Imidazoles; Jejunum; Male; Piperazine; Piperazines; Receptors, Histamine H3; Structure-Activity Relationship

2009
2-Butyl-4-chloroimidazole based substituted piperazine-thiosemicarbazone hybrids as potent inhibitors of Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry letters, 2014, Dec-01, Volume: 24, Issue:23

    Topics: Antitubercular Agents; Drug Design; Imidazoles; Mycobacterium tuberculosis; Piperazine; Piperazines; Structure-Activity Relationship; Thiosemicarbazones; Triazoles

2014
Metabolism of a 5HT
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:7

    Topics: Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Hepatocytes; Humans; Imidazoles; Isoenzymes; Ketoconazole; Microsomes, Liver; Piperazine; Piperazines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sulfonamides

2018
Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities.
    Chemical biology & drug design, 2019, Volume: 93, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Binding Sites; Imidazoles; Maze Learning; Mice; Microsomes, Liver; Molecular Dynamics Simulation; Permeability; Phosphoric Diester Hydrolases; Piperazine; Protein Binding; Protein Structure, Tertiary; Purines; Pyrimidines; Receptor, Serotonin, 5-HT1A; Structure-Activity Relationship

2019