imidazole and oxazoles

imidazole has been researched along with oxazoles in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's4 (21.05)18.2507
2000's4 (21.05)29.6817
2010's4 (21.05)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Fotsch, C; St Jean, DJ1
Carbone, D; Cascioferro, S; Cirrincione, G; Diana, P; Giovannetti, E; Parrino, B; Schillaci, D1
Berger, SB; Maiese, K; Pek, L; Reis, DJ1
Arrais, CA; Camargo, LA; Menani, JV; Renzi, A; Saad, R; Saad, WA; Silveira, JE1
Bousquet, P; Feldman, J; Pompermayer, K; Salgado, MC1
Golovinsky, EV; Jung, G; Stankova, IG; Videnov, GI1
Bolin, DR; Campbell, R; Cooper, JR; Cox, D; Gaizband, D; Makofske, R; Nagy, Z; Olson, GL; Sarabu, R1
BUTLER, TC; WADDELL, WJ1
BUTLER, TC; SMITH, JA; WADDELL, WJ1
BUTLER, TC1
Sames, D; Sezen, B1
Brum, TB; Leitão, GG; Lobato, AP; Pinto, AV; Pinto, Mdo C; Silva, RS1
Célanire, S; Christophe, B; Collart, P; Dassesse, D; de Esch, I; Delaunoy, C; Denonne, F; Durieu, V; Gelens, E; Gillard, M; Lallemand, B; Lamberty, Y; Lebon, F; Leurs, R; Nicolas, JM; Provins, L; Quéré, L; Snip, E; Talaga, P; Timmerman, H; Van Houtvin, N; Vanbellinghen, A; Verbois, V; Wijtmans, M1
Andersson, PG; Diéguez, M; Mazuela, J; Pàmies, O; Tolstoy, P1
Comba, P; Dovalil, N; Hanson, GR; Linti, G1
Brennan, E; Butler, E; Cacace, A; Chen, J; de Gaetano, M; Fallon, P; Gahan, K; Godson, C; Guiry, PJ; Hams, E; Leroy, X; Loscher, CE; Maingot, C; Marai, M; McLoughlin, A; Perretti, M; Zanetti, A1
Bode, ML; Coyanis, EM; Harrison, AT; Mosebi, S; Rashamuse, TJ; van Vuuren, S1
Mazhukin, DG; Zaytseva, EV1
Barnard, RJO; Chung, CC; Clausen, D; Deng, L; Duffy, JL; Fells, JI; Holloway, MK; Howell, BJ; Klein, DJ; Kozlowski, J; Liu, J; Myers, RW; Suzuki, T; Wang, M; Wu, G; Wu, J; Xu, S; Yu, W; Yu, Y1

Reviews

3 review(s) available for imidazole and oxazoles

ArticleYear
Mitigating heterocycle metabolism in drug discovery.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats

2012
Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance.
    Journal of medicinal chemistry, 2020, 08-13, Volume: 63, Issue:15

    Topics: Animals; Anti-Bacterial Agents; Benzene; Biofilms; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Thiazolidines

2020
Spirocyclic Nitroxides as Versatile Tools in Modern Natural Sciences: From Synthesis to Applications. Part I. Old and New Synthetic Approaches to Spirocyclic Nitroxyl Radicals.
    Molecules (Basel, Switzerland), 2021, Jan-28, Volume: 26, Issue:3

    Topics: Imidazoles; Imidazolidines; Morpholines; Natural Science Disciplines; Nitrogen Oxides; Oxazoles; Piperidines; Pyrrolidines; Reducing Agents

2021

Other Studies

16 other study(ies) available for imidazole and oxazoles

ArticleYear
Reduction in focal cerebral ischemia by agents acting at imidazole receptors.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brain; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Imidazoles; Ischemic Attack, Transient; Male; Neurons; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Drug; Rilmenidine

1992
Effect of rilmenidine injection into the paraventricular nucleus of the hypothalamus on the water intake induced by application of angiotensin II to the subfornical organ.
    Journal of physiology, Paris, 1997, Volume: 91, Issue:2

    Topics: Angiotensin II; Animals; Drinking; Idazoxan; Imidazoles; Injections; Male; Oxazoles; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Rilmenidine; Subfornical Organ

1997
Cardiovascular effects of clonidine-like drugs in pithed rabbits.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:4 Pt 2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Physiological Phenomena; Clonidine; Electric Stimulation; Heart Rate; Imidazoles; Male; Oxazoles; Rabbits; Rilmenidine; Sympathetic Nervous System; Synaptic Transmission

1999
Synthesis of thiazole, imidazole and oxazole containing amino acids for peptide backbone modification.
    Journal of peptide science : an official publication of the European Peptide Society, 1999, Volume: 5, Issue:9

    Topics: Amino Acids; Anti-Bacterial Agents; Bacteriocins; Imidazoles; Molecular Mimicry; Oxazoles; Peptides; Thiazoles

1999
Oxazole- and imidazole-based Ser-Leu dipeptide mimetics in potent inhibitors of antigen presentation by MHC class II DR molecules.
    Drug design and discovery, 2002, Volume: 18, Issue:1

    Topics: Antigen Presentation; Dipeptides; Genes, MHC Class II; Imidazoles; Immunosuppressive Agents; Leucine; Molecular Mimicry; Oxazoles; Serine

2002
N-methylated derivatives of barbituric acid, hydantoin and oxazolidinedione used in the treatment of epilepsy.
    Neurology, 1958, Volume: 8, Issue:Suppl 1

    Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Imidazoles; Oxazoles

1958
Demethylation of N-methyl derivatives of barbituric acid, hydantoin, and 2,4-oxazolidinedione by rat liver microsomes.
    Life sciences (1962), 1963, Issue:7

    Topics: Animals; Anticonvulsants; Barbiturates; Hydantoins; Imidazoles; Liver; Microsomes; Microsomes, Liver; Oxazoles; Rats

1963
The effects of N-methylation in 5,5-disubstituted derivatives of barbituric acid, hydantoin, and 2-4-oxazolidinedione.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1955, Volume: 44, Issue:6

    Topics: Anticonvulsants; Barbiturates; Hydantoins; Imidazoles; Methylation; Oxazoles

1955
Cobalt-catalyzed arylation of azole heteroarenes via direct C-H bond functionalization.
    Organic letters, 2003, Oct-02, Volume: 5, Issue:20

    Topics: Azoles; Catalysis; Cobalt; Hydrocarbons, Aromatic; Imidazoles; Oxazoles; Palladium

2003
Applications of counter-current chromatography in organic synthesis purification of heterocyclic derivatives of lapachol.
    Journal of chromatography. A, 2007, Jun-01, Volume: 1151, Issue:1-2

    Topics: Activating Transcription Factor 6; Chromatography, Thin Layer; Countercurrent Distribution; Cyclization; Imidazoles; Molecular Structure; Naphthoquinones; Oxazoles; Quinoxalines

2007
Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
    ChemMedChem, 2009, Volume: 4, Issue:7

    Topics: Animals; Caco-2 Cells; Cell Line; CHO Cells; Cricetinae; Cricetulus; Drug Design; Drug Inverse Agonism; Histamine H3 Antagonists; Humans; Imidazoles; Mice; Oxazoles; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Histamine H3; Structure-Activity Relationship

2009
Phosphite-oxazole/imidazole ligands in asymmetric intermolecular Heck reaction.
    Organic & biomolecular chemistry, 2011, Feb-07, Volume: 9, Issue:3

    Topics: Furans; Imidazoles; Ligands; Microwaves; Molecular Structure; Oxazoles; Phosphites; Stereoisomerism

2011
Synthesis and Cu(II) coordination chemistry of a patellamide derivative: consequences of the change from the natural thiazole/oxazoline to the artificial imidazole heterocycles.
    Inorganic chemistry, 2011, Jun-06, Volume: 50, Issue:11

    Topics: Amides; Copper; Crystallography, X-Ray; Heterocyclic Compounds; Imidazoles; Models, Molecular; Molecular Conformation; Organometallic Compounds; Oxazoles; Peptides, Cyclic; Quantum Theory; Stereoisomerism; Thiazoles

2011
Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: Animals; Cell Line; Humans; Imidazoles; Inflammation; Lipoxins; Mice; Molecular Mimicry; Monocytes; NF-kappa B; Oxazoles; Peritonitis; Receptors, Formyl Peptide

2019
Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGF/p75 disruptors and inhibitors of microbial pathogens.
    Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Oxazoles; Structure-Activity Relationship; Transcription Factors

2020
Discovery of Ethyl Ketone-Based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity.
    Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8

    Topics: Animals; Dogs; Drug Evaluation, Preclinical; ERG1 Potassium Channel; Half-Life; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; HIV-1; Humans; Imidazoles; Ketones; Oxazoles; Protein Isoforms; Rats; Structure-Activity Relationship; Virus Activation

2021