Compounds > imidazenil
Page last updated: 2024-09-03

imidazenil and isoflurophate

imidazenil has been researched along with isoflurophate in 5 studies

Compound Research Comparison

Studies
(imidazenil)		Trials
(imidazenil)		Recent Studies (post-2010)
(imidazenil)		Studies
(isoflurophate)		Trials
(isoflurophate)		Recent Studies (post-2010) (isoflurophate)
42063,3371123

Protein Interaction Comparison

ProteinTaxonomyimidazenil (IC50)isoflurophate (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)0.48
Lysosomal protective proteinHomo sapiens (human)10
Fatty acid synthase Rattus norvegicus (Norway rat)0.05
AcetylcholinesteraseHomo sapiens (human)0.12
Liver carboxylesteraseSus scrofa (pig)0.05

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auta, J; Costa, E; Davis, J; Guidotti, A1
Auta, J; Costa, E; Guidotti, A; Kadriu, B; Kozikowski, AP; Pibiri, F; Pinna, G1
Auta, J; Costa, E; Guidotti, A; Kadriu, B1
Auta, J; Costa, E; Davis, JM; Guidotti, A; Kadriu, B1
Auta, J; Davis, JM; Gocel, J; Guidotti, A; Kadriu, B; Larson, J; Nambiar, MP1

Other Studies

5 other study(ies) available for imidazenil and isoflurophate

ArticleYear
Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity.
    Neuropharmacology, 2004, Volume: 46, Issue:3

    Topics: Animals; Benzodiazepines; Diazepam; Imidazoles; Isoflurophate; Male; Neuroprotective Agents; Rats; Rats, Inbred F344; Seizures

2004
The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-16, Volume: 105, Issue:37

    Topics: Alkaloids; Animals; Benzodiazepines; Cognition Disorders; Drug Therapy, Combination; Imidazoles; Isoflurophate; Lethal Dose 50; Locomotion; Male; Mice; Seizures; Sesquiterpenes

2008
Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage.
    Toxicology, 2009, Feb-27, Volume: 256, Issue:3

    Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Brain; Cholinesterase Inhibitors; Diazepam; DNA Fragmentation; Electroencephalography; Imidazoles; In Situ Nick-End Labeling; Isoflurophate; Male; Neurons; Rats; Rats, Inbred F344; Seizures; Status Epilepticus; Telemetry

2009
Acute imidazenil treatment after the onset of DFP-induced seizure is more effective and longer lasting than midazolam at preventing seizure activity and brain neuropathology.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 120, Issue:1

    Topics: Animals; Anticonvulsants; Antigens, Nuclear; Benzodiazepines; Brain; Dose-Response Relationship, Drug; Imidazoles; Isoflurophate; Male; Midazolam; Nerve Tissue Proteins; Neurons; Rats; Rats, Inbred F344; Receptors, GABA; Seizures; Telemetry; Time Factors

2011
Absence of tolerance to the anticonvulsant and neuroprotective effects of imidazenil against DFP-induced seizure and neuronal damage.
    Neuropharmacology, 2011, Volume: 61, Issue:8

    Topics: Animals; Anticonvulsants; Benzodiazepines; Cholinesterase Inhibitors; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoresceins; Imidazoles; Isoflurophate; Male; Neurons; Neuroprotective Agents; Organic Chemicals; Rats; Rats, Inbred F344; Seizures; Statistics, Nonparametric

2011