imetit has been researched along with clobenpropit in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 18 (69.23) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Christiaans, JA; Gynther, J; Kotisaari, S; Kovalainen, JT; Laitinen, JT; Männistö, PT; Tuomisto, L | 1 |
| Chang, H; Erlander, MG; Lovenberg, TW; Pyati, J; Wilson, SJ | 1 |
| Arrang, JM; Gbahou, F; Héron, A; Ligneau, X; Morisset, S; Sasse, A; Schwartz, JC; Tardivel-Lacombe, J | 1 |
| Blevitt, J; Carruthers, N; Chai, W; Hofstra, CL; Jiang, X; Li, X; Liu, C; Lovenberg, TW; Ma, X; Pyati, J; Wilson, SJ | 1 |
| Anthes, JC; Bayne, M; Behan, J; Gonsiorek, W; Greene, J; Greenfeder, SA; Gustafson, EL; Hedrick, JA; Hipkin, RW; Laz, TM; Monsma, FJ; Morse, KL; Qiao, X; Shin, N; Umland, S; Wan, Y; Wang, S; West, RE | 1 |
| Audinot, V; Beauverger, P; Boutin, JA; Cogé, F; Galizzi, JP; Guénin, SP; Macia, C; Nagel, N; Ouvry, C; Renouard-Try, A; Rique, H | 1 |
| Kuei, C; Liu, C; Lovenberg, TW; Wilson, SJ | 1 |
| Bongers, G; Hashimoto, T; Leurs, R; Lovenberg, TW; Menge, WM; Timmerman, H; Wieland, K; Yamamoto, Y; Yamatodani, A | 1 |
| Hastrup, S; Rimvall, K; Wulff, BS | 1 |
| Chen, J; Liu, C; Lovenberg, TW | 1 |
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Falus, A; Jelinek, I; Keseru, GM; Kiss, B; Kiss, R; Könczöl, A; László, V; Noszál, B; Szalai, F | 1 |
| Bakker, RA; de Esch, IJ; Gobbi, S; Haaksma, EE; Istyastono, EP; Jongejan, A; Lahaye, R; Leurs, R; Lim, HD; Menge, WM; Romeo, G; Schepers, M; Smits, RA; van de Stolpe, A; Zuiderveld, OP | 1 |
| Ito, S; Mitobe, Y; Mizutani, T; Nagase, T; Sato, N; Tokita, S | 1 |
| Handzlik, J; Kieć-Kononowicz, K; Kottke, T; Ligneau, X; Schunack, W; Seifert, R; Stark, H; Więcek, M | 1 |
| de Esch, IJ; de Graaf, C; Istyastono, EP; Kooistra, AJ; Leurs, R; Lim, HD; Nijmeijer, S; Roumen, L; van de Stolpe, A; Vischer, HF | 1 |
| Grätz, L; Humphrys, LJ; Işbilir, A; Lohse, MJ; Möller, J; Nagl, M; Pockes, S; Rosier, N; Schihada, H; Seibel, U | 1 |
| Buczko, W; Godlewski, G; Malinowska, B; Schlicker, E | 1 |
| Schlicker, E; Werthwein, S; Zentner, J | 1 |
| Bacciottini, L; Bartolini, L; Blandina, P; Giovannini, MG; Greco, L | 1 |
| Blanco, I; Gomez-Ramirez, J; Ortiz, J | 1 |
| Brzozowski, T; Konturek, SJ; Obuchowicz, R; Pawlik, MW; Pawlik, WW | 1 |
| Biernat, J; Brzozowski, T; Konturek, SJ; Obuchowicz, R; Pawlik, MW; Pawlik, WW; Sendur, R | 1 |
| Blanks, AM; Lee, K; Renaud, LP; Spanswick, D; Whyment, AD | 1 |
| Barrett, P; Ebling, FJ; Enright, RA; Jethwa, PH; Murphy, M; Turnbull, Y; Warner, A | 1 |
| An, S; Chen, LY; Guo, XX; Hao, Q; Liu, Y; Ma, L; Pediani, JD; Tang, M; Ward, RJ; Wu, N; Xu, TR; Yang, Y; Zeng, H | 1 |
26 other study(ies) available for imetit and clobenpropit
| Article | Year |
|---|---|
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Ligands; Male; Propylamines; Rats; Rats, Wistar; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship | 1999 |
Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Methylhistamines; Molecular Sequence Data; Rats; Receptors, Histamine H3; Recombinant Proteins; RNA, Messenger | 2000 |
The rat H3 receptor: gene organization and multiple isoforms.
Topics: Animals; Autoradiography; Brain; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Frameshift Mutation; Genetic Variation; In Situ Hybridization; Introns; Iodine Radioisotopes; Organ Specificity; Protein Isoforms; Radioligand Assay; Rats; Receptors, Histamine H3; Recombinant Proteins; Sequence Deletion; Transcription, Genetic; Transfection | 2001 |
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Bone Marrow; Cloning, Molecular; Histamine; Humans; Methylhistamines; Molecular Sequence Data; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Tritium | 2001 |
Cloning and characterization of a novel human histamine receptor.
Topics: Amino Acid Sequence; Cells, Cultured; Cloning, Molecular; Histamine; Histamine Agonists; Humans; Imidazoles; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; RNA, Messenger; Sequence Homology, Amino Acid; Thiourea; Tissue Distribution; Transfection | 2001 |
Genomic organization and characterization of splice variants of the human histamine H3 receptor.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Fluorescence; Molecular Sequence Data; Protein Binding; Receptors, Histamine H3; Sequence Homology, Amino Acid; Sulfur Radioisotopes | 2001 |
Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; COS Cells; Cyclic AMP; DNA Fragmentation; Guinea Pigs; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Transfection | 2001 |
Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.
Topics: Animals; Burimamide; Cyclic AMP; Histamine Antagonists; Humans; Imidazoles; Male; Rats; Rats, Wistar; Receptors, Histamine H3; Recombinant Proteins; Thiourea; Tumor Cells, Cultured | 2001 |
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic | 2002 |
Molecular and pharmacological characterization of the mouse histamine H3 receptor.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Brain; Calcium; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Mice; Molecular Sequence Data; Rats; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Thiourea | 2003 |
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
Topics: Binding, Competitive; Cell Line, Tumor; Databases, Factual; Histamine Antagonists; Humans; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship | 2008 |
Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.
Topics: Histamine H3 Antagonists; Humans; Imidazoles; Ligands; Male; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Thiourea | 2009 |
Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Brain; Chemistry, Pharmaceutical; Drug Design; Humans; Kinetics; Ligands; Mice; Models, Chemical; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Histamine H3; Structure-Activity Relationship | 2009 |
N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands.
Topics: Carbamates; Histamine Antagonists; Humans; Ligands; Phthalimides; Protein Isoforms; Receptors, Histamine H3 | 2011 |
Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.
Topics: Cell Line, Tumor; Histamine Antagonists; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Quantitative Structure-Activity Relationship; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Thiourea | 2011 |
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H
Topics: Binding Sites; Bioluminescence Resonance Energy Transfer Techniques; Dose-Response Relationship, Drug; Fluorescent Dyes; HEK293 Cells; Histamine H3 Antagonists; Humans; Ligands; Molecular Structure; Receptors, Histamine H3; Single Molecule Imaging; Structure-Activity Relationship | 2021 |
Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; Hypertension; Imidazoles; Male; Methylhistamines; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagotomy; Vascular Resistance | 1997 |
Histamine H3 receptor-mediated inhibition of noradrenaline release in the human brain.
Topics: Animals; Brain; Cerebral Cortex; Dimethindene; Electric Stimulation; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Male; Mice; Mice, Inbred Strains; Norepinephrine; Piperidines; Ranitidine; Receptors, Histamine H3; Thiourea; Tritium | 1999 |
Effects of histamine H3 receptor agonists and antagonists on cognitive performance and scopolamine-induced amnesia.
Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cognition; Histamine Agonists; Histamine Antagonists; Imidazoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methylhistamines; Pattern Recognition, Visual; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Scopolamine; Thiourea | 1999 |
Presynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Colforsin; Cyclic AMP; Drug Interactions; Histamine; Imidazoles; In Vitro Techniques; Male; Piperidines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Thionucleotides; Thiourea | 2002 |
Involvement of central and peripheral histamine H(3) receptors in the control of the vascular tone and oxygen uptake in the mesenteric circulation of the rat.
Topics: Animals; Blood Pressure; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Imidazoles; Injections, Intra-Arterial; Injections, Intraventricular; Intestinal Mucosa; Intestines; Male; Microcirculation; Muscle, Smooth, Vascular; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Histamine H3; Splanchnic Circulation; Tachycardia; Thiourea; Time Factors; Vasoconstriction | 2004 |
Histamine H3 receptors modulate reactive hyperemia in rat gut.
Topics: Animals; Blood Pressure; Female; Histamine Agonists; Histamine Antagonists; Hyperemia; Imidazoles; Infusions, Intra-Arterial; Intestinal Mucosa; Intestines; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Rats; Rats, Wistar; Receptors, Histamine H3; Regional Blood Flow; Thiourea | 2004 |
Histamine excites neonatal rat sympathetic preganglionic neurons in vitro via activation of H1 receptors.
Topics: Action Potentials; Animals; Animals, Newborn; Autonomic Fibers, Preganglionic; Barium; Dimaprit; Female; Ganglia, Sympathetic; Histamine; Histamine Agonists; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium; Rats; Rats, Inbred WKY; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiourea; Triprolidine | 2006 |
The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.
Topics: Animals; Body Temperature; Cell Line, Transformed; Cricetinae; Disease Models, Animal; Eating; Histamine; Imidazoles; Injections, Intraventricular; Motor Activity; Obesity; Phodopus; Photoperiod; Piperidines; Receptors, Histamine H3; Seasons; Thiourea; Transfection | 2009 |
Visualization of the activation of the histamine H3 receptor (H3R) using novel fluorescence resonance energy transfer biosensors and their potential application to the study of H3R pharmacology.
Topics: Bacterial Proteins; Biosensing Techniques; Cyclic AMP; Fluorescence Resonance Energy Transfer; Gene Expression; Green Fluorescent Proteins; HEK293 Cells; Histamine; Histamine Agonists; Histamine H3 Antagonists; Humans; Imidazoles; Kinetics; Luminescent Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plasmids; Receptors, Histamine H3; Thiourea; Transfection; Tritium | 2018 |