imetit and alpha-methylhistamine

imetit has been researched along with alpha-methylhistamine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (23.08)18.2507
2000's15 (57.69)29.6817
2010's3 (11.54)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Imamura, M; Lander, HM; Levi, R; Seyedi, N1
Banks, K; Merali, Z1
Buczko, W; Godlewski, G; Malinowska, B; Schlicker, E1
Murakami, Y; Nakamura, K; Okada, S; Wang, M; Yokotani, K1
Bacciottini, L; Bartolini, L; Blandina, P; Giovannini, MG; Greco, L1
Debilly, G; Gigout, S; Lin, JS; Vanni-Mercier, G1
Hall, FS; Kitanaka, J; Kitanaka, N; Morita, Y; Nishiyama, N; Takemura, M; Tanaka, K; Tatsuta, T; Uhl, GR1
Leurs, R; Menge, WM; Timmerman, H; Vollinga, RC1
Christiaans, JA; Gynther, J; Kotisaari, S; Kovalainen, JT; Laitinen, JT; Männistö, PT; Tuomisto, L1
Chang, H; Erlander, MG; Lovenberg, TW; Pyati, J; Wilson, SJ1
Blevitt, J; Carruthers, N; Chai, W; Hofstra, CL; Jiang, X; Li, X; Liu, C; Lovenberg, TW; Ma, X; Pyati, J; Wilson, SJ1
Alston, J; Ames, RS; Bergsma, DJ; Boyce, R; Davenport, CM; Dytko, GM; Fitzgerald, LR; Herrity, NC; Hieble, JP; Li, X; Mannan, IJ; Michalovich, D; Sarau, HM; Tan, KB; Tierney, LA; Vawter, L; Wilson, S; Wu, H; Zhu, Y1
Anthes, JC; Bayne, M; Behan, J; Gonsiorek, W; Greene, J; Greenfeder, SA; Gustafson, EL; Hedrick, JA; Hipkin, RW; Laz, TM; Monsma, FJ; Morse, KL; Qiao, X; Shin, N; Umland, S; Wan, Y; Wang, S; West, RE1
Audinot, V; Beauverger, P; Boutin, JA; Cogé, F; Galizzi, JP; Guénin, SP; Macia, C; Nagel, N; Ouvry, C; Renouard-Try, A; Rique, H1
Kuei, C; Liu, C; Lovenberg, TW; Wilson, SJ1
Bongers, G; Hashimoto, T; Leurs, R; Lovenberg, TW; Menge, WM; Timmerman, H; Wieland, K; Yamamoto, Y; Yamatodani, A1
Hastrup, S; Rimvall, K; Wulff, BS1
Chen, J; Liu, C; Lovenberg, TW1
Furuichi, K; Hirano, K; Kazuta, Y; Kimura, R; Matsuda, A; Matsumoto, S; Natsume, K; Shuto, S; Yamada, S1
Arrang, JM; Fkyerat, A; Ganellin, CR; Garbarg, M; Ligneau, X; Pelloux-Léon, N; Piripitsi, A; Schunack, W; Schwartz, JC; Stark, H; Tertiuk, W1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Falus, A; Jelinek, I; Keseru, GM; Kiss, B; Kiss, R; Könczöl, A; László, V; Noszál, B; Szalai, F1
Ishikawa, M; Kakui, N; Kato, K; Nagayama, T; Okuma, K; Oyama, M; Sato, Y; Shinei, R; Yamauchi, M; Yokoyama, F1
Buschauer, A; Dove, S; Igel, P1
Capet, M; Krief, S; Labeeuw, O; Reiner, D; Stark, H; Zivkovic, A1
Grätz, L; Humphrys, LJ; Işbilir, A; Lohse, MJ; Möller, J; Nagl, M; Pockes, S; Rosier, N; Schihada, H; Seibel, U1

Other Studies

26 other study(ies) available for imetit and alpha-methylhistamine

ArticleYear
Functional identification of histamine H3-receptors in the human heart.
    Circulation research, 1995, Volume: 77, Issue:1

    Topics: Cell Separation; Electric Stimulation; Exocytosis; Heart; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; In Vitro Techniques; Indoles; Methylhistamines; Myocardial Ischemia; Myocardium; Norepinephrine; Piperidines; Protein Kinase C; Receptors, Histamine H3; Synaptosomes; Thiourea

1995
Does the histaminergic system mediate bombesin/GRP-induced suppression of food intake?
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2

    Topics: Animals; Behavior, Animal; Bombesin; Eating; Gastrin-Releasing Peptide; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Male; Methylhistamines; Motor Activity; Peptides; Piperidines; Rats; Rats, Sprague-Dawley; Satiation; Sincalide; Thiourea

1994
Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2

    Topics: Adrenergic Fibers; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; Hypertension; Imidazoles; Male; Methylhistamines; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagotomy; Vascular Resistance

1997
Histamine H(3) receptor-mediated inhibition of endogenous acetylcholine release from the isolated, vascularly perfused rat stomach.
    European journal of pharmacology, 2000, Mar-24, Volume: 392, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Gastric Mucosa; GTP-Binding Proteins; Histamine; Imidazoles; Male; Methylhistamines; Perfusion; Pertussis Toxin; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagus Nerve; Virulence Factors, Bordetella

2000
Effects of histamine H3 receptor agonists and antagonists on cognitive performance and scopolamine-induced amnesia.
    Behavioural brain research, 1999, Volume: 104, Issue:1-2

    Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cognition; Histamine Agonists; Histamine Antagonists; Imidazoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methylhistamines; Pattern Recognition, Visual; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Scopolamine; Thiourea

1999
Waking selective neurons in the posterior hypothalamus and their response to histamine H3-receptor ligands: an electrophysiological study in freely moving cats.
    Behavioural brain research, 2003, Sep-15, Volume: 144, Issue:1-2

    Topics: Action Potentials; Animals; Cats; Drug Administration Schedule; Electroencephalography; Electromyography; Electrooculography; Electrophysiology; Female; Geniculate Bodies; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Hypothalamus, Posterior; Imidazoles; Immunohistochemistry; Male; Methylhistamines; Neurons; Thiourea; Time Factors; Wakefulness

2003
Histamine H3 receptor agonists decrease hypothalamic histamine levels and increase stereotypical biting in mice challenged with methamphetamine.
    Neurochemical research, 2011, Volume: 36, Issue:10

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Histamine; Histamine Agonists; Hypothalamus; Imidazoles; Male; Methamphetamine; Methylhistamines; Mice; Motor Activity; Piperidines; Random Allocation; Stereotyped Behavior; Thiourea

2011
Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole.
    Journal of medicinal chemistry, 1995, Jan-20, Volume: 38, Issue:2

    Topics: Animals; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Jejunum; Magnetic Resonance Spectroscopy; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Structure-Activity Relationship

1995
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Animals; Autoradiography; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Ligands; Male; Propylamines; Rats; Rats, Wistar; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship

1999
Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Methylhistamines; Molecular Sequence Data; Rats; Receptors, Histamine H3; Recombinant Proteins; RNA, Messenger

2000
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.
    Molecular pharmacology, 2001, Volume: 59, Issue:3

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Bone Marrow; Cloning, Molecular; Histamine; Humans; Methylhistamines; Molecular Sequence Data; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Tritium

2001
Cloning, expression, and pharmacological characterization of a novel human histamine receptor.
    Molecular pharmacology, 2001, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Animals; Calcium; Cloning, Molecular; Dose-Response Relationship, Drug; Gene Expression; Genes, Reporter; Histamine; Humans; Luciferases; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; Sequence Homology, Amino Acid; Tissue Distribution; Tritium

2001
Cloning and characterization of a novel human histamine receptor.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: Amino Acid Sequence; Cells, Cultured; Cloning, Molecular; Histamine; Histamine Agonists; Humans; Imidazoles; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; RNA, Messenger; Sequence Homology, Amino Acid; Thiourea; Tissue Distribution; Transfection

2001
Genomic organization and characterization of splice variants of the human histamine H3 receptor.
    The Biochemical journal, 2001, Apr-15, Volume: 355, Issue:Pt 2

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Fluorescence; Molecular Sequence Data; Protein Binding; Receptors, Histamine H3; Sequence Homology, Amino Acid; Sulfur Radioisotopes

2001
Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1

    Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; COS Cells; Cyclic AMP; DNA Fragmentation; Guinea Pigs; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Transfection

2001
Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: Animals; Burimamide; Cyclic AMP; Histamine Antagonists; Humans; Imidazoles; Male; Rats; Rats, Wistar; Receptors, Histamine H3; Recombinant Proteins; Thiourea; Tumor Cells, Cultured

2001
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
    European journal of pharmacology, 2002, Oct-18, Volume: 453, Issue:1

    Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic

2002
Molecular and pharmacological characterization of the mouse histamine H3 receptor.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Brain; Calcium; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Mice; Molecular Sequence Data; Rats; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Thiourea

2003
Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.
    Journal of medicinal chemistry, 2003, May-08, Volume: 46, Issue:10

    Topics: Animals; Brain; CHO Cells; Cricetinae; Cyclopropanes; Histamine Agonists; Humans; Imidazoles; In Vitro Techniques; Male; Molecular Conformation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship

2003
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
    Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12

    Topics: Animals; Brain; Ethers; Histamine Agonists; Histamine Antagonists; Histamine Release; Imidazoles; Male; Methylhistamines; Mice; Rats; Receptors, Histamine H3; Structure-Activity Relationship; Sulfides; Synaptosomes

2004
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Binding, Competitive; Cell Line, Tumor; Databases, Factual; Histamine Antagonists; Humans; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship

2008
Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Administration, Oral; Animals; Brain Chemistry; Histamine; Histamine Agonists; Hydrophobic and Hydrophilic Interactions; Methylhistamines; Mice; Receptors, Histamine; Receptors, Histamine H3; Stress, Psychological; Structure-Activity Relationship

2010
Histamine H4 receptor agonists.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Animals; Benzimidazoles; Binding Sites; Clozapine; Guanidines; Humans; Ligands; Mice; Oximes; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship

2010
Novel pyrrolidinone derivative lacks claimed histamine H
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Dose-Response Relationship, Drug; Fluorescence Polarization; HEK293 Cells; Humans; Molecular Structure; Protein Binding; Pyrrolidinones; Receptors, Histamine H3; Structure-Activity Relationship

2020
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Binding Sites; Bioluminescence Resonance Energy Transfer Techniques; Dose-Response Relationship, Drug; Fluorescent Dyes; HEK293 Cells; Histamine H3 Antagonists; Humans; Ligands; Molecular Structure; Receptors, Histamine H3; Single Molecule Imaging; Structure-Activity Relationship

2021