Page last updated: 2024-09-03

ilomastat and batimastat

ilomastat has been researched along with batimastat in 5 studies

Compound Research Comparison

Studies
(ilomastat)
Trials
(ilomastat)
Recent Studies (post-2010)
(ilomastat)
Studies
(batimastat)
Trials
(batimastat)
Recent Studies (post-2010) (batimastat)
103045347656

Protein Interaction Comparison

ProteinTaxonomyilomastat (IC50)batimastat (IC50)
5-hydroxytryptamine receptor 3EHomo sapiens (human)0.025
5-hydroxytryptamine receptor 3BHomo sapiens (human)0.025
Interstitial collagenaseHomo sapiens (human)0.3158
Low affinity immunoglobulin epsilon Fc receptorHomo sapiens (human)0.1
72 kDa type IV collagenaseHomo sapiens (human)0.3029
Stromelysin-1Homo sapiens (human)1.1205
MatrilysinHomo sapiens (human)3.5012
Matrix metalloproteinase-9Homo sapiens (human)0.0066
Neutrophil collagenaseHomo sapiens (human)0.7
Metabotropic glutamate receptor 5Rattus norvegicus (Norway rat)1.2
Collagenase 3Homo sapiens (human)0.005
5-hydroxytryptamine receptor 3AHomo sapiens (human)0.025
Matrix metalloproteinase-14Homo sapiens (human)0.5715
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)0.0149
Snake venom metalloproteinase BaP1Bothrops asper (terciopelo)1.2
5-hydroxytryptamine receptor 3DHomo sapiens (human)0.025
5-hydroxytryptamine receptor 3CHomo sapiens (human)0.025

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Hori, N; Ikeda, S; Inoue, S; Ohishi, Y; Okada, Y; Tsujishita, H; Yamamoto, M1
Burslem, MF; Dickinson, RP; Fray, MJ1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Cambrey, AD; Daniels, JT; Garrett, Q; Khaw, PT; Occleston, NL; Schultz, GS; Tarnuzzer, RW1
Bildt, MM; Bloemen, M; Kuijpers-Jagtman, AM; Von den Hoff, JW1

Other Studies

5 other study(ies) available for ilomastat and batimastat

ArticleYear
Inhibition of membrane-type 1 matrix metalloproteinase by hydroxamate inhibitors: an examination of the subsite pocket.
    Journal of medicinal chemistry, 1998, Apr-09, Volume: 41, Issue:8

    Topics: Amino Acid Sequence; Dipeptides; Humans; Hydroxamic Acids; Ligands; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Models, Molecular; Mutation; Phenylalanine; Protease Inhibitors; Protein Conformation; Structure-Activity Relationship; Thiophenes

1998
Selectivity of inhibition of matrix metalloproteases MMP-3 and MMP-2 by succinyl hydroxamates and their carboxylic acid analogues is dependent on P3' group chirality.
    Bioorganic & medicinal chemistry letters, 2001, Feb-26, Volume: 11, Issue:4

    Topics: Hydroxamic Acids; Matrix Metalloproteinase Inhibitors; Protease Inhibitors; Structure-Activity Relationship

2001
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:3

    Topics: Cell Division; Cells, Cultured; Collagen Type I; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Hydroxamic Acids; Indoles; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Phenylalanine; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiophenes

2003
Matrix metalloproteinase inhibitors reduce collagen gel contraction and alpha-smooth muscle actin expression by periodontal ligament cells.
    Journal of periodontal research, 2009, Volume: 44, Issue:2

    Topics: Actins; Cell Culture Techniques; Cells, Cultured; Collagen; Dental Stress Analysis; Doxycycline; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Fibroblasts; Gels; Humans; Hydroxamic Acids; Indoles; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Periodontal Ligament; Phenylalanine; Protease Inhibitors; Tetracyclines; Thiophenes; Tissue Inhibitor of Metalloproteinases; Tooth Movement Techniques

2009