Page last updated: 2024-08-23

ilmofosine and edelfosine

ilmofosine has been researched along with edelfosine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19907 (24.14)18.7374
1990's13 (44.83)18.2507
2000's7 (24.14)29.6817
2010's1 (3.45)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Buettner, GR; Burns, CP; Wagner, BA1
Braquet, P; Principe, P; Sidoti, C1
Bauer, S; Remmele, T; Stricker, H; Sturm, V; Wowra, B; Zeller, WJ1
Kuo, JF; Oishi, K; Vogler, WR; White, JF; Zheng, B1
Berger, MR; Schmähl, D1
Berdel, WE; Bolscher, JG; Bruyneel, EA; Mareel, MM; Schallier, DC; Storme, GA1
Berdel, WE; Eibl, H; Fink, U; Fromm, M; Jehn, U; Rastetter, J; Reichert, A; Schick, HD; Ulm, K; Unger, C1
Berdel, WE; Busch, R; Danhauser, S; Eibl, H; Fink, U; Fromm, M; Rastetter, J; Reichert, A; Schick, HD1
Fiebig, HH; Leder, GH; Löhr, GW; Wallbrecher, E; Winterhalter, BR1
Andreesen, R; Costabel, U; Löhr, GW; Luckenbach, GA; Munder, PG; Osterholz, J; Schulz, A; Speth, V1
Magistrelli, A; Salmona, M; Tacconi, MT; Trulla, LL1
Hajdu, J; Kuo, JF; Olson, AC; Raynor, R; Shoji, M; Vogler, WR1
Berkovic, D; Fleer, EA; Grunwald, U; Hiddemann, W1
Croft, SL; Snowdon, D; Yardley, V1
Crilly, KS; Kiss, Z1
Berkovic, D; Fleer, EA; Hiddemann, W; Kuduz, J1
Arthur, G; Bittman, R1
Civoli, F; Daniel, LW1
Grosman, N2
de Castro, SL; Meirelles, MN; Santa-Rita, RM; Santos Barbosa, H1
Croft, SL; Duchêne, M; Seifert, K1
Barbosa, HS; de Castro, SL; Henriques-Pons, A; Santa-Rita, RM1
Azzouz, S; Garcia, RG; Maache, M; Osuna, A1
Azzouz, S; Dos Santos, MF; Maache, M; Osuna, A; Petavy, AF; Sarciron, ME1
Azzouz, S; Maache, M; Osuna, A; Petavy, AF; Sánchez-Moreno, M1
Azzouz, S; Maache, M; Osuna, A; Petavy, AF; Sarciron, ME1
Aslanidis, C; Buechler, C1
Bajorath, J; Batista, J; Braxmeier, T; Friedrichson, T; Jennings, G; Schlechtingen, G1

Reviews

3 review(s) available for ilmofosine and edelfosine

ArticleYear
The inhibition of cell signaling pathways by antitumor ether lipids.
    Biochimica et biophysica acta, 1998, Feb-05, Volume: 1390, Issue:1

    Topics: Animals; Antineoplastic Agents; Calcium; Furans; Humans; Phospholipid Ethers; Phosphorylcholine; Protein Kinases; Receptors, Cell Surface; Signal Transduction

1998
Antiprotozoal activities of phospholipid analogues.
    Molecular and biochemical parasitology, 2003, Volume: 126, Issue:2

    Topics: Animals; Antiprotozoal Agents; Leishmania; Parasitic Sensitivity Tests; Phospholipid Ethers; Phospholipids; Phosphorylcholine; Structure-Activity Relationship; Trypanosoma

2003
Role of lipids in pathophysiology, diagnosis and therapy of hepatocellular carcinoma.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020, Volume: 1865, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Proliferation; Diagnosis, Differential; Disease Models, Animal; Disease Progression; Humans; Lipid Metabolism; Lipids; Liver; Liver Cirrhosis; Liver Neoplasms; Oxidative Stress; Phospholipid Ethers; Phosphorylcholine; Plasmalogens; Severity of Illness Index

2020

Other Studies

26 other study(ies) available for ilmofosine and edelfosine

ArticleYear
Membrane peroxidative damage enhancement by the ether lipid class of antineoplastic agents.
    Cancer research, 1992, Nov-01, Volume: 52, Issue:21

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Cell Death; Drugs, Investigational; Fatty Acids; Free Radicals; Glutathione; Iron; Leukemia L1210; Lipid Peroxidation; Membrane Lipids; Phospholipid Ethers; Phospholipids; Vitamin E

1992
Tumor cell kinetics following antineoplastic ether phospholipid treatment.
    Cancer research, 1992, May-01, Volume: 52, Issue:9

    Topics: Antineoplastic Agents; Cell Cycle; Cell Division; Cytarabine; DNA; Drug Screening Assays, Antitumor; Flow Cytometry; G2 Phase; Humans; Mitosis; Phospholipid Ethers; S Phase; Tumor Cells, Cultured; Vinblastine

1992
Interstitial chemotherapy of experimental gliomas.
    Cancer treatment reviews, 1990, Volume: 17, Issue:2-3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Screening Assays, Antitumor; Glioma; Humans; Injections, Intralesional; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Phospholipid Ethers; Phosphorylcholine; Polyesters; Rats; Rats, Inbred Strains

1990
Inhibition of Na,K-ATPase and sodium pump by anticancer ether lipids and protein kinase C inhibitors ET-18-OCH3 and BM 41.440.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Membrane; Cerebral Cortex; Erythrocytes; Humans; Leukemia; Lysophosphatidylcholines; Ouabain; Phospholipid Ethers; Protein Kinase C; Rats; Sodium Channels; Sodium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Tumor Cells, Cultured

1988
Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Leukemia, Experimental; Lysophospholipids; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Organophosphates; Organophosphorus Compounds; Phospholipid Ethers; Rats; Rats, Inbred Strains

1987
Effect of lipid derivatives on invasion in vitro and on surface glycoproteins of three rodent cell types.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Line; Lysophospholipids; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Invasiveness; Organophosphates; Organophosphorus Compounds; Phospholipid Ethers; Piperidines; Rats; Tumor Cells, Cultured

1987
Cytotoxic effects of ether lipids and derivatives in human nonneoplastic bone marrow cells and leukemic cells in vitro.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Survival; Cytotoxins; Humans; Leukemia; Organophosphates; Phospholipid Ethers; Platelet Activating Factor; Thymidine; Tumor Cells, Cultured

1987
Structure-cytotoxicity studies on alkyl lysophospholipids and some analogs in leukemic blasts of human origin in vitro.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: Antineoplastic Agents; Cell Survival; Cytotoxins; Glyceryl Ethers; Humans; Leukemia; Lysophospholipids; Organophosphates; Phospholipid Ethers; Platelet Activating Factor; Tumor Cells, Cultured

1987
In vitro and in vivo cytotoxicity of alkyl lysophospholipid ET-18-OCH3 and thioether lipid BM 41.440.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cytotoxins; Glyceryl Ethers; Humans; Injections, Intraperitoneal; Leukemia, Experimental; Mice; Organophosphates; Organophosphorus Compounds; Phospholipid Ethers; Tumor Cells, Cultured

1987
Tumor cytotoxicity of human macrophages after incubation with synthetic analogues of 2-lysophosphatidylcholine.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:1

    Topics: Antineoplastic Agents; Cell Line; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Lymphoma; Lysophosphatidylcholines; Macrophage Activation; Macrophages; Phospholipid Ethers; Platelet Activating Factor

1984
Effect of cell density on cytotoxicity of ether lipid analogues in variants of B16 murine melanoma.
    Lipids, 1993, Volume: 28, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Count; Cell Survival; Cholesterol; Melanoma, Experimental; Mice; Phosphatidylcholines; Phospholipid Ethers; Phospholipids; Sphingomyelins; Tumor Cells, Cultured

1993
Structure-function relationships of alkyl-lysophospholipid analogs in selective antitumor activity.
    Lipids, 1993, Volume: 28, Issue:6

    Topics: Antineoplastic Agents; Cell Division; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Leukemia; Lysophospholipids; Phospholipid Ethers; Protein Kinase C; Structure-Activity Relationship; Tumor Cells, Cultured

1993
Induction of resistance to hexadecylphosphocholine in the highly sensitive human epidermoid tumour cell line KB.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:3

    Topics: Antineoplastic Agents; Choline; Drug Resistance, Neoplasm; Humans; Inositol; KB Cells; Phospholipid Ethers; Phosphorylcholine

1996
The activities of four anticancer alkyllysophospholipids against Leishmania donovani, Trypanosoma cruzi and Trypanosoma brucei.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:6

    Topics: Animals; Antineoplastic Agents; Chagas Disease; Cricetinae; Female; Furans; Leishmania donovani; Leishmaniasis, Visceral; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Phospholipid Ethers; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis, African

1996
Alkyl lysophospholipids inhibit phorbol ester-stimulated phospholipase D activity and DNA synthesis in fibroblasts.
    FEBS letters, 1997, Jul-28, Volume: 412, Issue:2

    Topics: 3T3 Cells; Animals; DNA Replication; Enzyme Activation; Fibroblasts; Mice; Phospholipase D; Phospholipid Ethers; Tetradecanoylphorbol Acetate

1997
Expression of two 50 kDa proteins is associated with sensitivity towards etherlipid analogues in the human leukaemia cell line HL 60.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:11

    Topics: Antineoplastic Agents; Cell Differentiation; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Neoplasm Proteins; Phospholipid Ethers; Phosphorylcholine

1997
Quaternary ammonium analogs of ether lipids inhibit the activation of protein kinase C and the growth of human leukemia cell lines.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:4

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Survival; Culture Media, Serum-Free; Drug Resistance; Enzyme Activation; Furans; HL-60 Cells; Humans; Phospholipid Ethers; Phosphorylcholine; Protein Kinase C; Quaternary Ammonium Compounds; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1998
Influence of probes for calcium-calmodulin and protein kinase C signalling on the plasma membrane Ca2+-ATPase activity of rat synaptosomes and leukocyte membranes.
    Immunopharmacology, 1998, Volume: 40, Issue:2

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Calmodulin; Cell Membrane; Enzyme Inhibitors; Gallic Acid; Imidazoles; Leukocytes; Male; Phosphodiesterase Inhibitors; Phospholipid Ethers; Phosphorylcholine; Protein Kinase C; Quercetin; Rats; Rats, Wistar; Signal Transduction; Sphingosine; Staurosporine; Synaptosomes

1998
Effect of the anti-neoplastic agents edelfosine (ET-18-OCH3), ilmofosine (BM 41.440) and the hexadecylphosphocholine analogues D-20133 and D-21266 on histamine release from isolated rat mast cells.
    Immunopharmacology, 1999, Volume: 44, Issue:3

    Topics: Animals; Antineoplastic Agents; Calcimycin; Histamine Release; Ionophores; Male; Mast Cells; Phorbol Esters; Phospholipid Ethers; Phosphorylcholine; Piperidines; Rats; Rats, Wistar

1999
Effect of the alkyl-lysophospholipids on the proliferation and differentiation of Trypanosoma cruzi.
    Acta tropica, 2000, Mar-25, Volume: 75, Issue:2

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Heart; Life Cycle Stages; Lysophospholipids; Macrophages; Mice; Microscopy, Electron; Phospholipid Ethers; Phosphorylcholine; Temperature; Time Factors; Trypanosoma cruzi

2000
Effect of the lysophospholipid analogues edelfosine, ilmofosine and miltefosine against Leishmania amazonensis.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:4

    Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Inhibitory Concentration 50; Leishmania; Lysophospholipids; Macrophages, Peritoneal; Mice; Microscopy, Electron; Phospholipid Ethers; Phosphorylcholine

2004
Leishmanicidal activity of edelfosine, miltefosine and ilmofosine.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 96, Issue:1

    Topics: Animals; Antiprotozoal Agents; Cell Line; DNA, Protozoan; Flow Cytometry; Leishmania donovani; Mice; Phospholipid Ethers; Phosphorylcholine; Protozoan Proteins; RNA, Protozoan

2005
Aspects of the cytological activity of edelfosine, miltefosine, and ilmofosine in Leishmania donovani.
    The Journal of parasitology, 2006, Volume: 92, Issue:5

    Topics: Animals; Antiprotozoal Agents; Apoptosis; Cell Cycle; Cell Line; Cricetinae; Female; Humans; Hydrogen-Ion Concentration; Leishmania donovani; Macrophages; Mice; Mice, Inbred BALB C; Phospholipid Ethers; Phosphorylcholine

2006
Effect of alkyl-lysophospholipids on some aspects of the metabolism of Leishmania donovani.
    The Journal of parasitology, 2007, Volume: 93, Issue:5

    Topics: Animals; Carbohydrate Metabolism; Humans; Leishmania donovani; Magnetic Resonance Spectroscopy; Parasitic Sensitivity Tests; Phospholipid Ethers; Phosphorylcholine; Protozoan Proteins; Superoxide Dismutase; Type C Phospholipases

2007
Study of the stress proteins secreted by Leishmania donovani after treatment with edelfosine, mitelfosine and ilmofosine, and morphological alterations analyzed by electronic microscopy.
    Parasite (Paris, France), 2009, Volume: 16, Issue:3

    Topics: Animals; Antineoplastic Agents; Autoradiography; Drug Resistance; Heat-Shock Proteins; Humans; Leishmania donovani; Leishmaniasis, Visceral; Microscopy, Electron; Phospholipid Ethers; Protozoan Proteins; World Health Organization

2009
Computational screening for membrane-directed inhibitors of mast cell activation.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Animals; Cell Degranulation; Cell Line, Tumor; Cell Membrane; Computational Biology; Computer Simulation; Drug Evaluation, Preclinical; Mast Cells; Models, Molecular; Molecular Conformation; Rats

2010