Page last updated: 2024-08-26

illudin s and sesquiterpenes

illudin s has been researched along with sesquiterpenes in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (25.64)	18.7374
1990's	14 (35.90)	18.2507
2000's	7 (17.95)	29.6817
2010's	8 (20.51)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Inoue, T; Kadota, S; Kikuchi, T; Tanaka, K	2
Kelner, MJ; McMorris, TC; Taetle, R	1
Hirosawa, A; Ishidate, M; Iwasaki, S; Matsuoka, A; Natori, S; Sofuni, T	1
Hirayama, E; Iwasaki, S; Koyama, K; Matsushima, T; Morisaki, N; Nagao, T; Natori, S; Saito, K; Uchikoshi, K	1
Beck, WT; Kelner, MJ; McMorris, TC; Taetle, R; Zamora, JM	1
Kawano, M	2
Inoue, T; Kanai, M; Kikuchi, T; Tanaka, K	1
Estes, L; Goldstein, J; Kelner, MJ; McMorris, TC; Montoya, M; Rutherford, M; Samson, K; Starr, R; Taetle, R	1
Diaz, MA; Estes, LA; Kelner, MJ; McMorris, TC; Taetle, R; Wang, W	1
Inoue, T; Kikuchi, T; Tanaka, K; Tezuka, Y	2
Inoue, T; Miyasaka, S; Tanaka, K	1
Estes, LA; Kelner, MJ; McMorris, TC; Taetle, R; Wang, W; Yu, J	1
Estes, L; Kelner, MJ; McMorris, TC; Montoya, MA; Rutherford, M; Samson, KM; Taetle, R	1
Bagnell, RD; Estes, L; Kelner, MJ; McMorris, TC; Montoya, MA; Rutherford, M; Samson, KM; Taetle, R; Uglik, SF	1
Elayadi, AN; Kelner, MJ; McMorris, TC; Yu, J	1
Huber, CG; Kirchmair, M; Pöder, R	1
Hoeijmakers, JH; Jaspers, NG; Kelner, MJ; McMorris, TC; Ng, JM; Raams, A; Takeda, S; Yamashita, YM	1
Liu, H; Pirrung, MC	1
Comisso, M; Koeppel, F; Larsen, AK; Poindessous, V; Raymond, E; Waters, SJ	1
KOMATSU, N; NAKANISHI, K; OHASHI, M; TADA, M; TERAKAWA, H; YAMADA, Y	1
INAGAKI, S; NAKANISHI, K; OHASHI, M; SUZUKI, N; TADA, M; YAMADA, Y	1
BHACCA, NS; NAKANISHI, K; OHASHI, M; TADA, M; YAMADA, Y	1
NAKANISHI, K; TADA, M; YAMADA, Y	1
ANCHEL, M; MCMORRIS, TC	1
Huang, A; Ibanez-Calero, S; Lehmann, VK; Rinehart, KL; Wilson, GR	1
Dick, RA; Kensler, TW; Yu, X	1
Liu, X; Sturla, SJ	1
Itou, T; Kasahara, Y	1
Liu, X; Pietsch, KE; Sturla, SJ	1
Gong, J; Neels, JF; Pietsch, KE; Sturla, SJ; Yu, X	1
Pietsch, KE; Sturla, SJ; van Midwoud, PM; Villalta, PW	1
Glatt, H; Meinl, W; Pietsch, KE; Sturla, SJ	1
Kasahara, Y	1
Cimmino, A; Dasari, R; Evidente, A; Evidente, M; Kiss, R; Kornienko, A; Lefranc, F; Mathieu, V; van Otterlo, WA; Vurro, M	1
Broberg, A; Menkis, A; Nord, C	1
Estes, LA; Kashinatham, A; Kelner, MJ; McMorris, TC; Staake, MD	1

Reviews

2 review(s) available for illudin s and sesquiterpenes

Article	Year
[Clinical toxicology of mushroom poisoning. Omphalotus guepiniformis]. Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2013, Volume: 26, Issue:3 Topics: Agaricales; Albumins; Animals; Chromatography, High Pressure Liquid; Fluid Therapy; Humans; Metoclopramide; Mice; Mushroom Poisoning; Polycyclic Sesquiterpenes; Sesquiterpenes	2013
Toward a Cancer Drug of Fungal Origin. Medicinal research reviews, 2015, Volume: 35, Issue:5 Topics: Androstadienes; Animals; Antineoplastic Agents; Aphidicolin; Biological Products; Clinical Trials as Topic; Cyclohexanes; Diketopiperazines; Disease Models, Animal; Drug Design; Drug Resistance, Neoplasm; Fatty Acids, Unsaturated; Female; Fungi; Humans; Macrolides; Male; Mice; Neoplasms; Polycyclic Sesquiterpenes; Sesquiterpenes; Trichothecenes; Wortmannin	2015

Article

Year

[Clinical toxicology of mushroom poisoning. Omphalotus guepiniformis].

Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2013, Volume: 26, Issue:3

Topics: Agaricales; Albumins; Animals; Chromatography, High Pressure Liquid; Fluid Therapy; Humans; Metoclopramide; Mice; Mushroom Poisoning; Polycyclic Sesquiterpenes; Sesquiterpenes

2013

Toward a Cancer Drug of Fungal Origin.

Medicinal research reviews, 2015, Volume: 35, Issue:5

Topics: Androstadienes; Animals; Antineoplastic Agents; Aphidicolin; Biological Products; Clinical Trials as Topic; Cyclohexanes; Diketopiperazines; Disease Models, Animal; Drug Design; Drug Resistance, Neoplasm; Fatty Acids, Unsaturated; Female; Fungi; Humans; Macrolides; Male; Mice; Neoplasms; Polycyclic Sesquiterpenes; Sesquiterpenes; Trichothecenes; Wortmannin

2015

Other Studies

37 other study(ies) available for illudin s and sesquiterpenes

Article	Year
Metabolism by rat liver cytosol of illudin S, a toxic substance of Lampteromyces japonicus. II. Characterization of illudin S-metabolizing enzyme. Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Cytosol; Dicumarol; Hydrogen-Ion Concentration; Liver; Male; NAD(P)H Dehydrogenase (Quinone); NADP; Oxygen; Polycyclic Sesquiterpenes; Quercetin; Rats; Rats, Inbred Strains; Sesquiterpenes; Vitamin K	1992
Metabolism of illudin S, a toxic principle of Lampteromyces japonicus, by rat liver. I. Isolation and identification of cyclopropane ring-cleavage metabolites. Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:7 Topics: Animals; Antibiotics, Antineoplastic; Basidiomycota; Chromatography, Thin Layer; Cyclopropanes; Liver; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Polycyclic Sesquiterpenes; Rats; Rats, Inbred Strains; Sesquiterpenes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet	1990
Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity. Journal of the National Cancer Institute, 1990, Oct-03, Volume: 82, Issue:19 Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Humans; Kinetics; Polycyclic Sesquiterpenes; Sesquiterpenes	1990
Mutagenicity of ptaquiloside, the carcinogen in bracken, and its related illudane-type sesquiterpenes. II. Chromosomal aberration tests with cultured mammalian cells. Mutation research, 1989, Volume: 215, Issue:2 Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Indans; Mutagens; Polycyclic Sesquiterpenes; Sesquiterpenes; Terpenes	1989
Mutagenicity of ptaquiloside, the carcinogen in bracken, and its related illudane-type sesquiterpenes. I. Mutagenicity in Salmonella typhimurium. Mutation research, 1989, Volume: 215, Issue:2 Topics: In Vitro Techniques; Indans; Mutagenicity Tests; Mutagens; Polycyclic Sesquiterpenes; Salmonella typhimurium; Sesquiterpenes; Structure-Activity Relationship; Terpenes	1989
Preclinical evaluation of illudins as anticancer agents. Cancer research, 1987, Jun-15, Volume: 47, Issue:12 Topics: Antineoplastic Agents; Cell Division; Cell Line; DNA; Drug Resistance; Glycoproteins; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Melanoma; Molecular Weight; Phenotype; Polycyclic Sesquiterpenes; Sesquiterpenes	1987
[Toxicological and immunochemical studies on identification of Lampteromyces japonicus]. Igaku kenkyu. Acta medica, 1986, Volume: 56, Issue:3 Topics: Basidiomycota; Molecular Weight; Polycyclic Sesquiterpenes; Proteins; Sesquiterpenes	1986
[Forensic toxicological studies on Lampteromyces poisoning. Identification of illudin S (lampterol)]. Igaku kenkyu. Acta medica, 1986, Volume: 56, Issue:1 Topics: Agaricales; Chromatography, Thin Layer; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Mushroom Poisoning; Polycyclic Sesquiterpenes; Sesquiterpenes	1986
Metabolism of illudin S, a toxic substance of Lampteromyces japonicus. IV. Urinary excretion of an illudin S metabolite in rat. Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:12 Topics: Agaricales; Animals; Chromatography, Liquid; Humans; Male; Mass Spectrometry; Mushroom Poisoning; Polycyclic Sesquiterpenes; Rats; Rats, Wistar; Sesquiterpenes	1994
Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents. Biochemical pharmacology, 1994, Jul-19, Volume: 48, Issue:2 Topics: Animals; Antibiotics, Antineoplastic; Carmustine; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA; DNA Damage; DNA Helicases; DNA-Binding Proteins; Mitomycins; Mutation; Polycyclic Sesquiterpenes; Sesquiterpenes	1994
Acylfulvenes, a new class of potent antitumor agents. Experientia, 1996, Jan-16, Volume: 52, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Polycyclic Sesquiterpenes; Sesquiterpenes; Spiro Compounds	1996
Metabolism of illudin S, a toxic substance of Lampteromyces japonicus: urinary excretion of mercapturic acids in rat. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:3 Topics: Acetylcysteine; Agaricales; Animals; Antibiotics, Antineoplastic; Glutathione; Male; Polycyclic Sesquiterpenes; Rats; Rats, Wistar; Sesquiterpenes; Subcellular Fractions	1996
Histopathological effects of illudin S, a toxic substance of poisonous mushroom, in rat. Human & experimental toxicology, 1996, Volume: 15, Issue:4 Topics: Animals; Antibiotics, Antineoplastic; Dose-Response Relationship, Drug; Duodenum; Male; Polycyclic Sesquiterpenes; Rats; Rats, Wistar; Sesquiterpenes; Stomach; Time Factors	1996
(Hydroxymethyl)acylfulvene: an illudin derivative with superior antitumor properties. Journal of natural products, 1996, Volume: 59, Issue:9 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Basidiomycota; Chromatography, Thin Layer; Crystallography, X-Ray; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Polycyclic Sesquiterpenes; Sesquiterpenes	1996
Michael-type addition of illudin S, a toxic substance from Lampteromyces japonicus, with cysteine and cysteine-containing peptides in vitro. Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:2 Topics: Amino Acid Sequence; Antibiotics, Antineoplastic; Basidiomycota; Chromatography, Thin Layer; Cysteine; Glutathione; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Polycyclic Sesquiterpenes; Sesquiterpenes; Spectrophotometry, Ultraviolet	1996
Characterization of cellular accumulation and toxicity of illudin S in sensitive and nonsensitive tumor cells. Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:1 Topics: Antibiotics, Antineoplastic; DNA; Drug Resistance, Multiple; Humans; Polycyclic Sesquiterpenes; Sesquiterpenes; Tumor Cells, Cultured	1997
Characterization of acylfulvene histiospecific toxicity in human tumor cell lines. Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:3 Topics: Antibiotics, Antineoplastic; Humans; Polycyclic Sesquiterpenes; Sesquiterpenes; Spiro Compounds; Structure-Activity Relationship; Tumor Cells, Cultured	1998
Metabolism of antitumor acylfulvene by rat liver cytosol. Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Biotransformation; Cytosol; Liver; Microsomes, Liver; Models, Molecular; Molecular Conformation; Molecular Structure; Polycyclic Sesquiterpenes; Rats; Sesquiterpenes; Spiro Compounds	1999
Identification of illudins in Omphalotus nidiformis and Omphalotus olivascens var. indigo by column liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry. Journal of chromatography. A, 1999, Feb-05, Volume: 832, Issue:1-2 Topics: Agaricales; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Mass Spectrometry; Mycotoxins; Polycyclic Sesquiterpenes; Sesquiterpenes; Spectrophotometry, Ultraviolet	1999
Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways. DNA repair, 2002, Dec-05, Volume: 1, Issue:12 Topics: Animals; Antineoplastic Agents; Cell Line; CHO Cells; Cricetinae; DNA; DNA Damage; DNA Ligases; DNA Repair; DNA Replication; Humans; Mice; Mutation; Polycyclic Sesquiterpenes; Sesquiterpenes; Transcription, Genetic	2002
Modular, parallel synthesis of an illudinoid combinatorial library. Organic letters, 2003, May-29, Volume: 5, Issue:11 Topics: Agaricales; Antibiotics, Antineoplastic; Combinatorial Chemistry Techniques; Cyclization; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Magnetic Resonance Spectroscopy; Polycyclic Sesquiterpenes; Sesquiterpenes	2003
Marked activity of irofulven toward human carcinoma cells: comparison with cisplatin and ecteinascidin. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:7 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carcinoma; Cell Line, Tumor; Cisplatin; Culture Media; Dioxoles; Drug Resistance, Neoplasm; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione Transferase; Humans; Isoquinolines; Models, Chemical; Plant Extracts; Polycyclic Sesquiterpenes; rho GTP-Binding Proteins; Sesquiterpenes; Tetrahydroisoquinolines; Time Factors; Trabectedin; Tumor Suppressor Protein p53	2003
Isolation of lampterol, an antiumour substance from Lampteromyces japonicus. Nature, 1963, Jan-19, Volume: 197 Topics: Agaricales; Antineoplastic Agents; Humans; Polycyclic Sesquiterpenes; Sesquiterpenes; Vegetables	1963
[Isolation of lampterol from Lampteromvces japonicus (Kawam) Sing]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1963, Volume: 83 Topics: Agaricales; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Polycyclic Sesquiterpenes; Sesquiterpenes	1963
STRUCTURE AND REACTIONS OF ILLUDIN-S (LAMPTEROL). Chemical & pharmaceutical bulletin, 1964, Volume: 12 Topics: Agaricales; Antineoplastic Agents; Chemistry Techniques, Analytical; Polycyclic Sesquiterpenes; Research; Sesquiterpenes	1964
STEREOCHEMISTRY OF ILLUDIN-S (LAMPTEROL). Chemical & pharmaceutical bulletin, 1964, Volume: 12 Topics: Agaricales; Antineoplastic Agents; Chemistry Techniques, Analytical; Polycyclic Sesquiterpenes; Research; Sesquiterpenes	1964
FUNGAL METABOLITES. THE STRUCTURES OF THE NOVEL SESQUITERPENOIDS ILLUDIN-S AND -M. Journal of the American Chemical Society, 1965, Apr-05, Volume: 87 Topics: Basidiomycota; Chemical Phenomena; Chemistry; Fungi; Metabolism; Polycyclic Sesquiterpenes; Research; Sesquiterpenes; Terpenes	1965
Illudin S, the sole antiviral compound in mature fruiting bodies of Omphalotus illudens. Journal of natural products, 2003, Volume: 66, Issue:9 Topics: Agaricales; Animals; Antiviral Agents; Cells, Cultured; Fibroblasts; Haplorhini; Herpesvirus 1, Human; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polycyclic Sesquiterpenes; Sesquiterpenes	2003
NADPH alkenal/one oxidoreductase activity determines sensitivity of cancer cells to the chemotherapeutic alkylating agent irofulven. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-15, Volume: 10, Issue:4 Topics: Alcohol Oxidoreductases; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutathione; Humans; Ketones; Kinetics; Mass Spectrometry; Models, Chemical; Polycyclic Sesquiterpenes; Sensitivity and Specificity; Sesquiterpenes; Time Factors; Transfection	2004
Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues. Molecular bioSystems, 2009, Volume: 5, Issue:9 Topics: Antineoplastic Agents, Alkylating; Catalytic Domain; Cell Line, Tumor; Chromatography, Liquid; Enzyme Inhibitors; Glutathione Disulfide; Glutathione Reductase; Humans; Inhibitory Concentration 50; Mass Spectrometry; NADP; Polycyclic Sesquiterpenes; Sesquiterpenes; Spiro Compounds; Systems Biology	2009
[Determination of illudin S in Omphalotus guepiniformis and foods that caused food poisoning by liquid chromatography with tandem mass spectrometry]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2009, Volume: 50, Issue:4 Topics: Agaricales; Chromatography, Liquid; Food Analysis; Humans; Mushroom Poisoning; Polycyclic Sesquiterpenes; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2009
Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes. Chemical research in toxicology, 2011, May-16, Volume: 24, Issue:5 Topics: Agaricales; Alkylation; Antineoplastic Agents; Antioxidants; Cell Survival; Cysteine; Enzyme Inhibitors; Glutathione Peroxidase; HeLa Cells; Humans; Neoplasms; Polycyclic Sesquiterpenes; Selenocysteine; Sesquiterpenes; Spiro Compounds; Thioredoxin-Disulfide Reductase	2011
Chemical and enzymatic reductive activation of acylfulvene to isomeric cytotoxic reactive intermediates. Chemical research in toxicology, 2011, Nov-21, Volume: 24, Issue:11 Topics: Alcohol Dehydrogenase; Alkylation; Animals; Antibiotics, Antineoplastic; Biotransformation; Borohydrides; Cell Line, Tumor; Cell Survival; DNA; Enzyme Activation; Humans; NADP; Neoplasms; Polycyclic Sesquiterpenes; Rats; Sesquiterpenes; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship	2011
Quantification of acylfulvene- and illudin S-DNA adducts in cells with variable bioactivation capacities. Chemical research in toxicology, 2013, Jan-18, Volume: 26, Issue:1 Topics: Alkylation; Animals; Antibiotics, Antineoplastic; Cattle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Humans; Polycyclic Sesquiterpenes; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spiro Compounds	2013
Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Archives of toxicology, 2014, Volume: 88, Issue:1 Topics: Animals; Arylsulfotransferase; Cell Line; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Humans; Mutagenicity Tests; Mutagens; Mutation; Polycyclic Sesquiterpenes; Salmonella typhimurium; Sesquiterpenes; Sister Chromatid Exchange; Spiro Compounds; Sulfotransferases	2014
Cytotoxic Illudane Sesquiterpenes from the Fungus Granulobasidium vellereum (Ellis and Cragin) Jülich. Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11 Topics: Basidiomycota; Cytotoxins; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polycyclic Sesquiterpenes; Sesquiterpenes; Stereoisomerism	2015
Hydroxyurea derivatives of irofulven with improved antitumor efficacy. Bioorganic & medicinal chemistry letters, 2016, Apr-01, Volume: 26, Issue:7 Topics: Acetylation; Agaricales; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Humans; Hydroxyurea; Mice, Inbred BALB C; Neoplasms; Polycyclic Sesquiterpenes; Sesquiterpenes	2016