Page last updated: 2024-08-26

illudin s and irofulven

illudin s has been researched along with irofulven in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kelner, MJ; McMorris, TC; Moon, SS1
Estes, LA; Kelner, MJ; McMorris, TC; Taetle, R; Wang, W; Yu, J1
Hoeijmakers, JH; Jaspers, NG; Kelner, MJ; McMorris, TC; Ng, JM; Raams, A; Takeda, S; Yamashita, YM1
Comisso, M; Koeppel, F; Larsen, AK; Poindessous, V; Raymond, E; Waters, SJ1
Dick, RA; Kensler, TW; Yu, X1
Glatt, H; Meinl, W; Pietsch, KE; Sturla, SJ1
Estes, LA; Kashinatham, A; Kelner, MJ; McMorris, TC; Staake, MD1

Other Studies

7 other study(ies) available for illudin s and irofulven

ArticleYear
Reaction of irofulven with zinc and acid.
    Journal of natural products, 2003, Volume: 66, Issue:2

    Topics: Acetic Acid; Antineoplastic Agents, Alkylating; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Indenes; Indicators and Reagents; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Sesquiterpenes; Zinc

2003
(Hydroxymethyl)acylfulvene: an illudin derivative with superior antitumor properties.
    Journal of natural products, 1996, Volume: 59, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Basidiomycota; Chromatography, Thin Layer; Crystallography, X-Ray; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Polycyclic Sesquiterpenes; Sesquiterpenes

1996
Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways.
    DNA repair, 2002, Dec-05, Volume: 1, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Line; CHO Cells; Cricetinae; DNA; DNA Damage; DNA Ligases; DNA Repair; DNA Replication; Humans; Mice; Mutation; Polycyclic Sesquiterpenes; Sesquiterpenes; Transcription, Genetic

2002
Marked activity of irofulven toward human carcinoma cells: comparison with cisplatin and ecteinascidin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:7

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carcinoma; Cell Line, Tumor; Cisplatin; Culture Media; Dioxoles; Drug Resistance, Neoplasm; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione Transferase; Humans; Isoquinolines; Models, Chemical; Plant Extracts; Polycyclic Sesquiterpenes; rho GTP-Binding Proteins; Sesquiterpenes; Tetrahydroisoquinolines; Time Factors; Trabectedin; Tumor Suppressor Protein p53

2003
NADPH alkenal/one oxidoreductase activity determines sensitivity of cancer cells to the chemotherapeutic alkylating agent irofulven.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-15, Volume: 10, Issue:4

    Topics: Alcohol Oxidoreductases; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutathione; Humans; Ketones; Kinetics; Mass Spectrometry; Models, Chemical; Polycyclic Sesquiterpenes; Sensitivity and Specificity; Sesquiterpenes; Time Factors; Transfection

2004
Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells.
    Archives of toxicology, 2014, Volume: 88, Issue:1

    Topics: Animals; Arylsulfotransferase; Cell Line; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Humans; Mutagenicity Tests; Mutagens; Mutation; Polycyclic Sesquiterpenes; Salmonella typhimurium; Sesquiterpenes; Sister Chromatid Exchange; Spiro Compounds; Sulfotransferases

2014
Hydroxyurea derivatives of irofulven with improved antitumor efficacy.
    Bioorganic & medicinal chemistry letters, 2016, Apr-01, Volume: 26, Issue:7

    Topics: Acetylation; Agaricales; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Humans; Hydroxyurea; Mice, Inbred BALB C; Neoplasms; Polycyclic Sesquiterpenes; Sesquiterpenes

2016