ilaprazole has been researched along with omeprazole in 14 studies
| Studies (ilaprazole) | Trials (ilaprazole) | Recent Studies (post-2010) (ilaprazole) | Studies (omeprazole) | Trials (omeprazole) | Recent Studies (post-2010) (omeprazole) |
|---|---|---|---|---|---|
| 53 | 24 | 42 | 9,085 | 2,737 | 1,487 |
| Protein | Taxonomy | ilaprazole (IC50) | omeprazole (IC50) |
|---|---|---|---|
| Mcl-1 | Homo sapiens (human) | 3.1448 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 0.28 | |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | 1.45 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 2.315 | |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | 1.45 | |
| WD repeat-containing protein 5 | Homo sapiens (human) | 1.7 | |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | 4.6 | |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | 1.7 | |
| Muscarinic acetylcholine receptor | Cavia porcellus (domestic guinea pig) | 3.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Boileau, F; Cho, KD; Goldwater, R; Jung, WT; Kim, DY; Lee, SM; Park, DW; Periclou, AP | 1 |
| Chae, JB; Cho, KD; Huh, IH; Kim, DY; Kim, EJ; Kim, YS; Kwon, D; Lee, SM; Park, CW | 1 |
| Goh, KL; Ho, KY; Kim, DY; Kuan, A; Mahachai, V; Yoon, HM; Zaño, F | 1 |
| Hou, XH; Hu, HT; Lin, SR; Qin, XH; Shi, RH; Xia, JL; Yang, YS; Yuan, YZ; Zhang, ST; Zhou, LY | 1 |
| Hu, H; Lin, S; Wang, L; Xia, J; Zhou, L | 2 |
| DU, YQ; Gong, YF; Guo, WY; He, J; Hu, JH; Li, Z; Li, ZS; Lu, JP; Zhan, XB; Zou, DW | 1 |
| Chen, Y; Cheng, H; Cui, MH; Gao, HJ; Gao, W; Hu, FL; Lü, NH; Sheng, JQ; Xie, Y; Xu, JM; Yang, GB; Yang, L; Zhang, GX; Zhang, L; Zhang, LX; Zhang, ZY | 1 |
| Blandizzi, C; de Bortoli, N; Giacchino, M; Marchi, S; Martinucci, I; Savarino, E; Savarino, V | 1 |
| Kim, EH; Kim, HY; Lee, SK; Park, CH; Roh, YH | 1 |
| Liu, Z; Lu, WQ; Lu, YJ; Song, RL; Xu, GX; Xuan, JW | 1 |
| Arnaud, B; Arnoult, C; Escoffier, J; Hograindleur, JP; Kaba, M; Le Blévec, E; Martinez, G; Nef, S; Ray, PF; Stévant, I | 1 |
| Chen, F; Fang, B; He, X; Wang, S | 1 |
| Cheng, X; Han, T; Jin, R; Li, J; Li, K | 1 |
2 review(s) available for ilaprazole and omeprazole
| Article | Year |
|---|---|
The pharmacokinetics of ilaprazole for gastro-esophageal reflux treatment.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cytochrome P-450 CYP2C19; Drug Evaluation, Preclinical; Gastroesophageal Reflux; Half-Life; Humans; Omeprazole; Proton Pump Inhibitors; Randomized Controlled Trials as Topic | 2013 |
The association between the use of proton pump inhibitors and the risk of hypomagnesemia: a systematic review and meta-analysis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Dexlansoprazole; Esomeprazole; Humans; Lansoprazole; Magnesium; Odds Ratio; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Rabeprazole; Risk Factors; Treatment Outcome | 2014 |
7 trial(s) available for ilaprazole and omeprazole
| Article | Year |
|---|---|
A comparative pharmacodynamic study of IY-81149 versus omeprazole in patients with gastroesophageal reflux disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Analysis of Variance; Anti-Ulcer Agents; Area Under Curve; Benzimidazoles; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastric Acid; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Omeprazole; Sulfoxides | 2000 |
Randomized, parallel, double-blind comparison of the ulcer-healing effects of ilaprazole and omeprazole in the treatment of gastric and duodenal ulcers.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Stomach Ulcer; Sulfoxides | 2009 |
[Evaluation of the effect of ilaprazole on intragastric pH in patients with duodenal ulcer].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Double-Blind Method; Duodenal Ulcer; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Stomach; Sulfoxides; Young Adult | 2010 |
A new PPI, ilaprazole compared with omeprazole in the treatment of duodenal ulcer: a randomized double-blind multicenter trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Double-Blind Method; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Sulfoxides; Treatment Outcome | 2011 |
Ilaprazole for the treatment of duodenal ulcer: a randomized, double-blind and controlled phase III trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cytochrome P-450 CYP2C19; Double-Blind Method; Duodenal Ulcer; Female; Genotype; Humans; Male; Middle Aged; Omeprazole; Polymorphism, Genetic; Sulfoxides; Treatment Outcome; Young Adult | 2012 |
Acid inhibition effect of ilaprazole on Helicobacter pylori-negative healthy volunteers: an open randomized cross-over study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cross-Over Studies; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gastric Acid; Gastric Acidity Determination; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Male; Omeprazole; Polymorphism, Genetic; Proton Pump Inhibitors; Reference Values; Stomach; Sulfoxides; Young Adult | 2012 |
[Ilaprazole based bismuth-containing quadruple regimen for the first-line treatment of Helicobacter pylori infection: a multicenter, randomized, controlled clinical study].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; China; Drug Therapy, Combination; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Young Adult | 2012 |
5 other study(ies) available for ilaprazole and omeprazole
| Article | Year |
|---|---|
Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aminopyrine; Animals; Anti-Ulcer Agents; Benzimidazoles; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Male; Omeprazole; Pentagastrin; Proton Pump Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Stomach; Sulfoxides | 2001 |
Modeling the cost-effectiveness of ilaprazole versus omeprazole for the treatment of newly diagnosed duodenal ulcer patients in China.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; China; Cost-Benefit Analysis; Decision Trees; Drug Costs; Duodenal Ulcer; Female; Humans; Male; Models, Economic; Omeprazole | 2016 |
Pantoprazole, a proton-pump inhibitor, impairs human sperm motility and capacitation in vitro.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Fertilization; Humans; Lansoprazole; Male; Membrane Potentials; Middle Aged; Omeprazole; Pantoprazole; Phosphorylation; Proton Pump Inhibitors; Rabeprazole; Retrospective Studies; Semen Analysis; Sperm Capacitation; Sperm Maturation; Sperm Motility; Spermatozoa; Young Adult | 2020 |
Simultaneous Quantitative Analysis of Six Proton-Pump Inhibitors with a Single Marker and Evaluation of Stability of Investigated Drugs in Polypropylene Syringes for Continuous Infusion Use.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chromatography, High Pressure Liquid; Drugs, Investigational; Esomeprazole; Humans; Lansoprazole; Molecular Structure; Omeprazole; Pantoprazole; Polypropylenes; Proton Pump Inhibitors; Rabeprazole | 2020 |
The influence of different proton pump inhibitors and potassium-competitive acid blockers on indomethacin-induced small intestinal injury.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; DNA, Ribosomal; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lipopolysaccharides; Mice; Omeprazole; Potassium; Proton Pump Inhibitors; Pyrroles; Rabeprazole; Sulfonamides | 2022 |