iguratimod has been researched along with warfarin in 2 studies
| Studies (iguratimod) | Trials (iguratimod) | Recent Studies (post-2010) (iguratimod) | Studies (warfarin) | Trials (warfarin) | Recent Studies (post-2010) (warfarin) |
|---|---|---|---|---|---|
| 134 | 19 | 109 | 36,573 | 2,143 | 14,728 |
| Protein | Taxonomy | iguratimod (IC50) | warfarin (IC50) |
|---|---|---|---|
| Vitamin K epoxide reductase complex subunit 1 | Homo sapiens (human) | 0.0088 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsuzawa, N; Ohmori, S; Sakuyama, K; Shiozawa, A; Takami, K; Yamaori, S | 1 |
| Hasegawa, K; Onoda, M; Tanaka, K; Yamamoto, T | 1 |
2 other study(ies) available for iguratimod and warfarin
| Article | Year |
|---|---|
In vitro inhibition of CYP2C9-mediated warfarin 7-hydroxylation by iguratimod: possible mechanism of iguratimod-warfarin interaction.
Topics: Aged; Antirheumatic Agents; Chromones; Cytochrome P-450 CYP2C9; Drug Interactions; Humans; Hydroxylation; Immunosuppressive Agents; Inhibitory Concentration 50; Kinetics; Liver; Microsomes, Liver; Stereoisomerism; Sulfonamides; Warfarin | 2015 |
Pharmacokinetic and Pharmacodynamic Analyses of Drug-Drug Interactions between Iguratimod and Warfarin.
Topics: Administration, Oral; Animals; Anticoagulants; Antirheumatic Agents; Blood Coagulation Factors; Chromones; Drug Interactions; Drug Therapy, Combination; Hemorrhage; Male; Product Surveillance, Postmarketing; Prothrombin Time; Rats, Wistar; Severity of Illness Index; Sulfonamides; Vitamin K; Warfarin | 2016 |