Compounds > iguratimod
Page last updated: 2024-09-03

iguratimod and tofacitinib

iguratimod has been researched along with tofacitinib in 2 studies

Compound Research Comparison

Studies
(iguratimod)		Trials
(iguratimod)		Recent Studies (post-2010)
(iguratimod)		Studies
(tofacitinib)		Trials
(tofacitinib)		Recent Studies (post-2010) (tofacitinib)
134191091,6192141,519

Protein Interaction Comparison

ProteinTaxonomyiguratimod (IC50)tofacitinib (IC50)
Chain A, Tyrosine-protein kinaseHomo sapiens (human)0.0117
Chain A, Tyrosine-protein kinaseHomo sapiens (human)0.0117
Chain A, Tyrosine-protein kinase JAK2Homo sapiens (human)0.0117
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)0.0815
Tyrosine-protein kinase JAK2Homo sapiens (human)0.2065
Rho-associated protein kinase 2Homo sapiens (human)3.4
Epidermal growth factor receptorHomo sapiens (human)0.0815
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0815
Tyrosine-protein kinase LckHomo sapiens (human)2.6933
Cytochrome P450 3A4Homo sapiens (human)0.015
Cytochrome P450 2C8Homo sapiens (human)0.0014
Cytochrome P450 2D6Homo sapiens (human)0.0037
Cytochrome P450 2A6Homo sapiens (human)0.012
Tyrosine-protein kinase JAK1Homo sapiens (human)0.0575
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.1411
Cytochrome P450 2C19Homo sapiens (human)0.0016
Tyrosine-protein kinase TecHomo sapiens (human)0.0815
Tyrosine-protein kinase TXKHomo sapiens (human)0.0815
Tyrosine-protein kinase BlkHomo sapiens (human)0.0815
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)0.0815
Tyrosine-protein kinase JAK3Homo sapiens (human)0.0408
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.0006
Tyrosine-protein kinase BTKHomo sapiens (human)0.0815
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)0.0815
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.0815
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.0143
Tyrosine-protein kinase JAK3Mus musculus (house mouse)0.664
Tyrosine-protein kinase JAK2Rattus norvegicus (Norway rat)3.57
Tyrosine-protein kinase JAK3Rattus norvegicus (Norway rat)1.2
Serine/threonine-protein kinase TBK1Homo sapiens (human)5.76

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Ikari, K; Inoue, E; Ishida, O; Koenuma, N; Koyama, T; Momohara, S; Ochi, K; Sakuma, Y; Taniguchi, A; Yamanaka, H; Yano, K; Yoshida, S1
Che, Q; Chen, J; Kou, Y; Li, M; Rong, X; Shu, Q; Zhang, X1

Other Studies

2 other study(ies) available for iguratimod and tofacitinib

ArticleYear
Recent trends in orthopedic surgery aiming to improve quality of life for those with rheumatoid arthritis: data from a large observational cohort.
    The Journal of rheumatology, 2014, Volume: 41, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chromones; Cohort Studies; Databases, Factual; Female; Humans; Japan; Joints; Male; Orthopedic Procedures; Piperidines; Pyrimidines; Pyrroles; Quality of Life; Sulfonamides; Tacrolimus

2014
A novel drug combination of Tofacitinib and Iguratimod alleviates rheumatoid arthritis and secondary osteoporosis.
    International immunopharmacology, 2023, Volume: 124, Issue:Pt B

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Drug Combinations; Humans; Osteoporosis; Rats; Tumor Necrosis Factor-alpha; X-Ray Microtomography

2023