ifosfamide and methylene blue

ifosfamide has been researched along with methylene blue in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (27.50)	18.2507
2000's	13 (32.50)	29.6817
2010's	10 (25.00)	24.3611
2020's	6 (15.00)	2.80

Authors

Authors	Studies
Aeschlimann, C; Cerny, T; Küpfer, A; Wermuth, B	1
Dreyfus, G; Eftekari, P; Ferrero, JM; Largillier, R; Namer, M	1
Maton, B; Tullen, E; Zulian, GB	1
Demandt, M; Wandt, H	1
Aeschlimann, C; Cerny, T; Küpfer, A	2
Alonso, JL; Díaz-Rubio, E; López, JA; Martín, M; Nieto, Y	1
Koschuth, A; Possinger, K; Späth-Schwalbe, PE	1
Aeschlimann, C; Cerny, T; Küpfer, A; Schefer, H	1
Foxall, PJ; Hartley, JM; Lapsley, M; Neild, GH; Nicholson, JK; Singer, JM; Souhami, RL	1
Budd, GT; Gurm, HS	1
De Vos, F; Pelgrims, J; Prové, A; Schrijvers, D; Van den Brande, J; Vermorken, JB	1
Beijnen, JH; de Kraker, J; Groen, HJ; Jansen, RL; Keizer, HJ; Kerbusch, T; Schellens, JH; van Putten, JW	1
Stewart, SL	1
Duong, CD; Good, DJ; Turner, AR	1
Bertolone, SJ; Jaffe, N; Raj, AB	1
David, KA; Picus, J	1
Idle, JR; Küpfer, A; Lauterburg, BH; Lerch, S	1
Behar, C; Dufour, C; Grill, J; Hartmann, O; Motte, J; Munzer, M; Oberlin, O; Paci, A; Sabouraud, P	1
Patel, PN	1
Alici-Evcimen, Y; Breitbart, WS	1
Basso, U; Brunello, A; Crivellari, G; Ghiotto, C; Marino, D; Monfardini, S; Rossi, E; Stefani, M	1
Hatfield Seung, A; Howell, JE; Nesbit, SA; Szabatura, AH	1
Beri, R; Shord, SS; Sweiss, KI	1
Hasan, M; Lorke, DE; Oz, M; Petroianu, GA	1
Bayliff, S; Bernard, PA; Hayes, D; McCabe, T	1
Chang, FW; Liu, YL; Tsai, SH; Yu, MH	1
Marshall, H; McQuary, A; Richards, A	1
Fisher, DC; McDonnell, AM; Rybak, I; Wadleigh, M	1
Miri-Aliabad, G	1
HaDuong, JH; Yeo, KK	1
Bärlund, M; Sunela, K	1
Bellien, J; Duflot, T; Filhon, B; Joannidès, R; Lamoureux, F; Marie-Cardine, A; Massy-Guillemant, N; Pereira, T; Verstuyft, C	1
Gharaibeh, EZ; Powers, BC; Salacz, ME; Telfah, M	1
Atay, AA; Demir, ÜF; Malbora, B; Sarbay, H; Yılmaz, G	1
Abahssain, H; Errihani, H; Essangri, H; Fadhil, FZ; Guessous, F; Meddah, B; Moukafih, B; Mrabti, H; Souadka, A	1
Ataseven, E; Göktepe, ŞÖ; Kantar, M	1
Campino, GA; Chain, G; Kalia, M; Kestenbaum, K; Pappas, L; Sechser-Perl, A; Zaghloul, N	1
Anlar, B; Aydin, B; Günbey, C; Müngen, E; Öz, S; Yaman Bajin, İ	1
Beyoğlu, D; Idle, JR	1

Reviews

10 review(s) available for ifosfamide and methylene blue

Article	Year
Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature. British journal of cancer, 2000, Volume: 82, Issue:2 Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Ifosfamide; Infusions, Intravenous; Male; Methylene Blue; Middle Aged; Neoplasms; Treatment Outcome	2000
Clinical pharmacokinetics and pharmacodynamics of ifosfamide and its metabolites. Clinical pharmacokinetics, 2001, Volume: 40, Issue:1 Topics: Animals; Antineoplastic Agents, Alkylating; Area Under Curve; Cyclophosphamide; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fanconi Syndrome; Humans; Ifosfamide; Methylene Blue; Neurotoxicity Syndromes; Stereoisomerism	2001
Evaluating risk factors for the development of ifosfamide encephalopathy. American journal of clinical oncology, 2005, Volume: 28, Issue:3 Topics: Adult; Aged; Akathisia, Drug-Induced; Antineoplastic Agents, Alkylating; Brain Diseases; Cohort Studies; Confusion; Creatinine; Female; Hallucinations; Humans; Hypoalbuminemia; Ifosfamide; Male; Methylene Blue; Middle Aged; Neoplasms; Odds Ratio; Prevalence; Retrospective Studies; Risk Factors	2005
Methylene blue for management of Ifosfamide-induced encephalopathy. The Annals of pharmacotherapy, 2006, Volume: 40, Issue:2 Topics: Humans; Ifosfamide; MEDLINE; Methylene Blue; Neurotoxicity Syndromes; Time Factors; Treatment Outcome	2006
Ifosfamide neuropsychiatric toxicity in patients with cancer. Psycho-oncology, 2007, Volume: 16, Issue:10 Topics: Adult; Antineoplastic Agents, Alkylating; Burkitt Lymphoma; Delusions; Enzyme Inhibitors; Female; Humans; Ifosfamide; Methylene Blue; Neurotoxicity Syndromes; Prognosis; Psychoses, Substance-Induced	2007
Encephalopathy after high-dose Ifosfamide: a retrospective cohort study and review of the literature. Drug safety, 2008, Volume: 31, Issue:11 Topics: Adult; Albumins; Antineoplastic Agents, Alkylating; Bilirubin; Brain Diseases; Cohort Studies; Enzyme Inhibitors; Female; Hemoglobins; Humans; Ifosfamide; Male; Methylene Blue; Middle Aged; Nervous System Diseases; Obesity; Retrospective Studies; Risk Factors; Sarcoma; Sex Factors	2008
Cellular and molecular actions of Methylene Blue in the nervous system. Medicinal research reviews, 2011, Volume: 31, Issue:1 Topics: Alzheimer Disease; Animals; Humans; Ifosfamide; Methemoglobinemia; Methylene Blue; Neurons	2011
[Treatment and prevention of iphosphamide-induced encephalopathy]. Duodecim; laaketieteellinen aikakauskirja, 2016, Volume: 132, Issue:4 Topics: Antiemetics; Antineoplastic Agents, Alkylating; Aprepitant; Drug Interactions; Enzyme Inhibitors; Humans; Ifosfamide; Methylene Blue; Morpholines; Neurotoxicity Syndromes	2016
A novel case of prolonged Ifosfamide encephalopathy and long-term treatment with methylene blue: a case report and review of literature. BMC pediatrics, 2022, 02-02, Volume: 22, Issue:1 Topics: Brain Diseases; Child; Female; Humans; Ifosfamide; Methylene Blue; Neurotoxicity Syndromes; Sleepiness	2022
Ifosfamide - History, efficacy, toxicity and encephalopathy. Pharmacology & therapeutics, 2023, Volume: 243 Topics: Antineoplastic Agents; Brain Diseases; Cyclophosphamide; Humans; Ifosfamide; Methylene Blue	2023

Trials

1 trial(s) available for ifosfamide and methylene blue

Article	Year
Comparative pharmacokinetics of oral and intravenous ifosfamide/mesna/methylene blue therapy. Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:9 Topics: Administration, Oral; Adult; Aged; Antidotes; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Expectorants; Female; Humans; Ifosfamide; Injections, Intravenous; Male; Mesna; Methylene Blue; Middle Aged	1998

Article

Year

Comparative pharmacokinetics of oral and intravenous ifosfamide/mesna/methylene blue therapy.

Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:9

Topics: Administration, Oral; Adult; Aged; Antidotes; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Expectorants; Female; Humans; Ifosfamide; Injections, Intravenous; Male; Mesna; Methylene Blue; Middle Aged

1998

Other Studies

29 other study(ies) available for ifosfamide and methylene blue

Article	Year
Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue. Lancet (London, England), 1994, Mar-26, Volume: 343, Issue:8900 Topics: Administration, Oral; Adolescent; Antidotes; Bone Neoplasms; Brain Diseases; Drug Overdose; Female; Glutarates; Humans; Ifosfamide; Injections, Intravenous; Lung Neoplasms; Methylene Blue; Osteosarcoma; Premedication; Sarcosine	1994
[Treatment of ifosfamide induced encephalopathy with methylene-blue]. Bulletin du cancer, 1995, Volume: 82, Issue:7 Topics: Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Female; Humans; Ifosfamide; Methylene Blue; Peritoneal Neoplasms; Uterine Neoplasms	1995
Methylene blue for ifosfamide-associated encephalopathy. The New England journal of medicine, 1995, May-04, Volume: 332, Issue:18 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Carcinoma, Squamous Cell; Cisplatin; Female; Humans; Ifosfamide; Methylene Blue; Uterine Cervical Neoplasms	1995
[Successful treatment with methylene blue of ifosfamide-induced central nervous system effects]. Deutsche medizinische Wochenschrift (1946), 1996, Apr-26, Volume: 121, Issue:17 Topics: Antidotes; Antineoplastic Agents, Alkylating; Brain Diseases; Humans; Ifosfamide; Male; Methylene Blue; Middle Aged	1996
Methylene blue and the neurotoxic mechanisms of ifosfamide encephalopathy. European journal of clinical pharmacology, 1996, Volume: 50, Issue:4 Topics: Administration, Oral; Animals; Antidotes; Antineoplastic Agents, Alkylating; Brain Diseases; Drug Therapy, Combination; Hepatic Encephalopathy; Humans; Ifosfamide; Methylene Blue; Oxidation-Reduction; Rats	1996
Ifosfamide encephalopathy and methylene-blue: a case report. Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:6 Topics: Brain Diseases; Female; Humans; Ifosfamide; Methylene Blue; Middle Aged	1996
[Methylene blue in ifosfamide-induced encephalopathy]. Deutsche medizinische Wochenschrift (1946), 1996, Sep-27, Volume: 121, Issue:39 Topics: Antineoplastic Agents, Alkylating; Brain Diseases; Female; Humans; Ifosfamide; Methylene Blue; Middle Aged	1996
Inhibition of (mono)amine oxidase activity and prevention of ifosfamide encephalopathy by methylene blue. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:12 Topics: Alkylation; Animals; Antidotes; Antineoplastic Agents; Brain Diseases; Cattle; Ifosfamide; In Vitro Techniques; Liver; Male; Methylene Blue; Mice; Monoamine Oxidase Inhibitors; Perfusion; Rats; Rats, Wistar	1996
Urinary proton magnetic resonance studies of early ifosfamide-induced nephrotoxicity and encephalopathy. Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:9 Topics: Adult; Amino Acids; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Brain Diseases; Dicarboxylic Acids; Humans; Ifosfamide; Kidney Cortex; Kidney Diseases; Kidney Function Tests; Kidney Medulla; Magnetic Resonance Spectroscopy; Mesna; Methylene Blue; Molecular Weight; Neoplasms; Protons; Retinol-Binding Proteins; Urinalysis	1997
A 47-year-old man with leiomyosarcoma and altered mental status. Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:1 Topics: Brain Diseases; Fatal Outcome; Humans; Ifosfamide; Leiomyosarcoma; Male; Methylene Blue; Middle Aged; Neurobehavioral Manifestations; Physical Examination; Retroperitoneal Neoplasms	1999
Postchemotherapy confusion. Oncology nursing forum, 2001, Volume: 28, Issue:9 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Female; Humans; Ifosfamide; Mesna; Methylene Blue; Neurotoxicity Syndromes; Oncology Nursing; Osteosarcoma	2001
Methylene blue for the treatment and prophylaxis of ifosfamide-induced encephalopathy. Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:7 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Female; Humans; Ifosfamide; Male; Methylene Blue; Neurotoxicity Syndromes	2003
Methylene blue reversal of ifosfamide-related encephalopathy. Journal of pediatric hematology/oncology, 2004, Volume: 26, Issue:2 Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Electroencephalography; Enzyme Inhibitors; Humans; Ifosfamide; Magnetic Resonance Imaging; Male; Methylene Blue; Neurotoxicity Syndromes; Osteosarcoma; Tomography, X-Ray Computed	2004
Cerebral formation in situ of S-carboxymethylcysteine after ifosfamide administration to mice: a further clue to the mechanism of ifosfamide encephalopathy. Toxicology letters, 2006, Mar-01, Volume: 161, Issue:3 Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Diseases; Carbocysteine; Drug Interactions; Drug Therapy, Combination; Female; Glutamic Acid; Ifosfamide; Methylene Blue; Mice; Monoamine Oxidase Inhibitors; Serotonin	2006
[Ifosfamide induced encephalopathy: 15 observations]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:2 Topics: Adolescent; Antineoplastic Agents, Alkylating; Child; Child, Preschool; Coma; Enzyme Inhibitors; Fatigue; Female; Humans; Ifosfamide; Male; Methylene Blue; Neoplasms; Neurotoxicity Syndromes; Retrospective Studies; Seizures	2006
Ifosfamide-related encephalopathy in elderly patients : report of five cases and review of the literature. Drugs & aging, 2007, Volume: 24, Issue:11 Topics: Abdominal Neoplasms; Aged; Antidotes; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Confusion; Fatal Outcome; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Methylene Blue; Multiple Myeloma; Neurotoxicity Syndromes; Psychomotor Agitation; Risk Assessment; Sarcoma; Uterine Neoplasms	2007
Characterization of the occurrence of ifosfamide-induced neurotoxicity with concomitant aprepitant. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2008, Volume: 14, Issue:3 Topics: Antidotes; Antiemetics; Antineoplastic Agents, Alkylating; Aprepitant; Delirium; Female; Humans; Ifosfamide; Kidney Function Tests; Liver Function Tests; Male; Methylene Blue; Middle Aged; Morpholines; Neuropsychological Tests; Neurotoxicity Syndromes; Retrospective Studies; Sarcoma	2008
Successful treatment of ifosfamide neurotoxicity with dexmedetomidine. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2010, Volume: 16, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Antidotes; Antineoplastic Agents, Alkylating; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Ifosfamide; Methylene Blue; Neurotoxicity Syndromes; Rhabdomyosarcoma; Treatment Outcome	2010
Ifosfamide-induced encephalopathy in patients with uterine sarcoma. Taiwanese journal of obstetrics & gynecology, 2010, Volume: 49, Issue:1 Topics: Aged; Antineoplastic Agents, Alkylating; Female; Humans; Ifosfamide; Methylene Blue; Middle Aged; Neoplasm Recurrence, Local; Neurotoxicity Syndromes; Sarcoma; Thiamine; Uterine Neoplasms; Vitamin B Complex	2010
Evaluation of methylene blue, thiamine, and/or albumin in the prevention of ifosfamide-related neurotoxicity. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:4 Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Humans; Ifosfamide; Methylene Blue; Middle Aged; Neurotoxicity Syndromes; Retrospective Studies; Serum Albumin; Thiamine	2011
Suspected serotonin syndrome in a patient being treated with methylene blue for ifosfamide encephalopathy. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2012, Volume: 18, Issue:4 Topics: Brain Diseases; Humans; Ifosfamide; Methylene Blue; Serotonin Syndrome	2012
Green urine secondary to methylene blue. Indian journal of pediatrics, 2014, Volume: 81, Issue:11 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Child; Diagnosis, Differential; Etoposide; Humans; Ifosfamide; Male; Methylene Blue; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Urine	2014
The Use of Continuous Veno-Venous Hemodiafiltration in the Management of Ifosfamide-induced Encephalopathy: A Case Report. Journal of pediatric hematology/oncology, 2016, Volume: 38, Issue:6 Topics: Antineoplastic Agents, Alkylating; Brain Diseases; Child; Female; Hemodiafiltration; Humans; Ifosfamide; Methylene Blue; Neuroblastoma	2016
Possible role of CYP2B6 genetic polymorphisms in ifosfamide-induced encephalopathy: report of three cases. Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:3 Topics: Administration, Intravenous; Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Diseases; Child; Cytochrome P-450 CYP2B6; Female; Genetic Predisposition to Disease; Humans; Ifosfamide; Male; Methylene Blue; Neuroprotective Agents; Osteosarcoma; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Treatment Outcome	2018
Hydration, methylene blue, and thiamine as a prevention regimen for ifosfamide-induced encephalopathy. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Etoposide; Female; Humans; Ifosfamide; Lymphoma, Large B-Cell, Diffuse; Methylene Blue; Middle Aged; Rituximab; Thiamine	2019
Ifosfamide induced encephalopathy in a child with osteosarcoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:5 Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Diseases; Female; Humans; Ifosfamide; Methylene Blue; Neurotoxicity Syndromes; Osteosarcoma	2021
Methylene blue and ifosfamide-induced encephalopathy: Myth or reality? Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:1 Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Diseases; Creatinine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Ifosfamide; Infusions, Intravenous; Male; Methylene Blue; Middle Aged; Morocco; Retrospective Studies; Tomography, X-Ray Computed	2021
Ifosfamide-related encephalopathy with severe clinical presentations in children with cancer. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:8 Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Diseases; Child; Female; Humans; Ifosfamide; Methylene Blue; Neoplasms	2021
Ifosfamide-induced Encephalopathy With Rapid Response to Thiamine: A Pediatric Case. Journal of pediatric hematology/oncology, 2022, 10-01, Volume: 44, Issue:7 Topics: Antineoplastic Agents, Alkylating; Brain Diseases; Child; Cisplatin; Creatinine; Humans; Ifosfamide; Methylene Blue; Serum Albumin; Thiamine	2022