ifenprodil has been researched along with haloperidol in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 10 (31.25) | 24.3611 |
| 2020's | 6 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Akunne, HC; Belliotti, TR; Brink, WA; Corbin, AE; Georgic, LM; Heffner, TG; Pugsley, TA; Shih, YH; Whetzel, SZ; Wise, LD; Wustrow, DJ; Zoski, KT | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Fermeglia, M; Florio, C; Laurini, E; Mamolo, MG; Paneni, MS; Posocco, P; Pricl, S; Vio, L; Zampieri, D; Zanette, C | 1 |
| Frehland, B; Schepmann, D; Schmidtke, KU; Tewes, B; Winckler, T; Wünsch, B | 1 |
| Sen, S; Sinha, N | 1 |
| Buemi, MR; Chimirri, A; De Luca, L; Ferro, S; Gitto, R; Parenti, C; Prezzavento, O; Ronsisvalle, S; Scala, A | 1 |
| Bonifazi, A; Gawaskar, S; Schepmann, D; Wünsch, B | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Dey, S; Frehland, B; Lehmkuhl, K; Schepmann, D; Schreiber, JA; Seebohm, G; Strutz-Seebohm, N; Temme, L; Wünsch, B | 1 |
| Dey, S; Schepmann, D; Wünsch, B | 1 |
| Kitamura, M; Schepmann, D; Shuto, Y; Temme, L; Thum, S; Wünsch, B | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Baumeister, S; Schepmann, D; Wünsch, B | 1 |
| Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y | 1 |
| Calabretti, A; Fortuna, S; Mamolo, MG; Menegazzi, R; Romano, M; Schepmann, D; Wünsch, B; Zampieri, D | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Itkin, M; Kabir, M; Mathé, EA; Nguyễn, ÐT; Padilha, EC; Shah, P; Shinn, P; Siramshetty, V; Wang, AQ; Williams, J; Xu, X; Yu, KR; Zhao, T | 1 |
| Borosky, SA; Clissold, DB; Ferkany, JW; Goode, S; Karbon, EW; Patch, RJ; Pontecorvo, MJ | 1 |
| Bakker, MH; Foster, AC | 1 |
| Hashimoto, K; London, ED; Scheffel, U | 1 |
| Bermoser, K; Glossmann, H; Hanner, M; Moebius, FF; Reiter, RJ | 1 |
| Cordon, JJ; Coughenour, LL | 1 |
| Pahk, AJ; Williams, K | 1 |
| Gallagher, MJ; Huang, H; Lynch, DR | 1 |
| Aizenman, E; Brimecombe, JC; Gallagher, MJ; Lynch, DR | 1 |
| Bermoser, K; Cho, SY; Glossmann, H; Moebius, FF; Paik, YK; Reiter, RJ | 1 |
| Gallagher, MJ; Guttmann, RP; Kurapathi, S; Lynch, DR; Mutel, V; Seifert, KM; Shim, SS | 1 |
| Hashimoto, K; Hattori, K; Iyo, M; Yanahashi, S; Yuasa, S | 1 |
| Evangelou, A; Kiortsis, DN; Konitsiotis, S; Tsironis, C | 1 |
| Geballe, MT; Low, CM; Ng, FM; Snyder, JP; Traynelis, SF | 1 |
| Asukai, N; Haraguchi, A; Hori, T; Ikeda, K; Ogai, Y; Senoo, E | 1 |
| Buyukuysal, RL; Gul, Z; Gursoy, M | 1 |
1 review(s) available for ifenprodil and haloperidol
| Article | Year |
|---|---|
Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability.
Topics: Administration, Oral; Animals; Betamethasone; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Cells, Cultured; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Madin Darby Canine Kidney Cells; Mice; Molecular Structure; Neural Networks, Computer; Ranitidine; Rats; Structure-Activity Relationship; Verapamil | 2022 |
31 other study(ies) available for ifenprodil and haloperidol
| Article | Year |
|---|---|
A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: discovery of a potential atypical antipsychotic agent.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; CHO Cells; Corpus Striatum; Cricetinae; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hippocampus; Magnetic Resonance Spectroscopy; Oxazines; Rats; Receptors, Dopamine D4 | 1999 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives.
Topics: Animals; Benzene; Computational Biology; Ligands; Models, Molecular; Molecular Conformation; Oxazoles; Rats; Receptors, sigma; Sigma-1 Receptor | 2009 |
Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.
Topics: Analgesics; Animals; Benzazepines; Humans; Mice; Microsomes, Liver; Neuralgia; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
From NMDA receptor antagonists to discovery of selective σ₂ receptor ligands.
Topics: Binding Sites; Glutamic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Structure-Activity Relationship | 2014 |
Synthesis, GluN2B affinity and selectivity of benzo[7]annulen-7-amines.
Topics: Benzocycloheptenes; Dose-Response Relationship, Drug; Humans; Molecular Structure; Piperazines; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2014 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Deconstruction - reconstruction approach to analyze the essential structural elements of tetrahydro-3-benzazepine-based antagonists of GluN2B subunit containing NMDA receptors.
Topics: Benzazepines; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2017 |
2-Methyltetrahydro-3-benzazepin-1-ols - The missing link in SAR of GluN2B selective NMDA receptor antagonists.
Topics: Benzazepines; Dose-Response Relationship, Drug; Humans; Molecular Docking Simulation; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2018 |
Do GluN2B subunit containing NMDA receptors tolerate a fluorine atom in the phenylalkyl side chain?
Topics: | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Thiophene bioisosteres of GluN2B selective NMDA receptor antagonists: Synthesis and pharmacological evaluation of [7]annuleno[b]thiophen-6-amines.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Molecular Structure; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Thiophenes | 2020 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins | 2020 |
Synthesis, Cytotoxicity Evaluation, and Computational Insights of Novel 1,4-Diazepane-Based Sigma Ligands.
Topics: | 2020 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents.
Topics: Animals; Anticonvulsants; Brain Diseases; Electroshock; Haloperidol; Hypoxia; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nimodipine; Piperidines; Postural Balance; Pyrimidines; Receptors, Opioid; Receptors, sigma; Seizures | 1991 |
An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Convulsants; Corpus Striatum; Dialysis; Diazepam; Dizocilpine Maleate; Glutamate Decarboxylase; Haloperidol; Ibotenic Acid; Injections; Male; Nerve Degeneration; Pipecolic Acids; Piperazines; Piperidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1991 |
In vivo labeling of sigma receptors in mouse brain with [3H]4-phenyl-1-(4-phenylbutyl)piperidine.
Topics: Animals; Binding, Competitive; Brain Chemistry; Haloperidol; Injections, Intravenous; Ligands; Male; Mice; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1995 |
Yeast sterol C8-C7 isomerase: identification and characterization of a high-affinity binding site for enzyme inhibitors.
Topics: Animals; Base Sequence; Binding Sites; DNA Primers; Enzyme Inhibitors; Ergosterol; Guinea Pigs; Haloperidol; Kinetics; Ligands; Mutation; Piperidines; Receptors, sigma; Saccharomyces cerevisiae; Steroid Isomerases; Trifluperidol | 1996 |
Characterization of haloperidol and trifluperidol as subtype-selective N-methyl-D-aspartate (NMDA) receptor antagonists using [3H]TCP and [3H]ifenprodil binding in rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Female; Haloperidol; Illicit Drugs; Kinetics; Oocytes; Phencyclidine; Piperidines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Trifluperidol; Xenopus | 1997 |
Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes.
Topics: Animals; Excitatory Amino Acid Antagonists; Haloperidol; Hydrogen-Ion Concentration; Neuroprotective Agents; Nylidrin; Oocytes; Patch-Clamp Techniques; Piperidines; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1997 |
Modulation of the N-methyl-D-aspartate receptor by haloperidol: NR2B-specific interactions.
Topics: Amino Acid Sequence; Binding, Competitive; Chimera; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Humans; Mutagenesis, Site-Directed; Piperidines; Receptors, N-Methyl-D-Aspartate; Spermidine | 1998 |
An NR2B point mutation affecting haloperidol and CP101,606 sensitivity of single recombinant N-methyl-D-aspartate receptors.
Topics: Animals; Arginine; CHO Cells; Cricetinae; Dizocilpine Maleate; Dopamine Antagonists; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Iodine Radioisotopes; Piperidines; Point Mutation; Receptors, N-Methyl-D-Aspartate | 1998 |
Pharmacological analysis of sterol delta8-delta7 isomerase proteins with [3H]ifenprodil.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Carrier Proteins; Dopamine Antagonists; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Guinea Pigs; Haloperidol; Isoenzymes; Kinetics; Mice; Microsomes; Microsomes, Liver; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Tamoxifen; Tritium | 1998 |
Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.
Topics: Animals; Brain; Cell Line; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Humans; Kinetics; Mice; Mutation; Phenols; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Spermidine | 2001 |
Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Catalepsy; Cell Count; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Drug Interactions; Ethylenediamines; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Haloperidol; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Piperidines; Prazosin; Prosencephalon; Proto-Oncogene Proteins c-fos; Reaction Time; Receptors, N-Methyl-D-Aspartate; Time Factors | 2004 |
Effects of N-methyl-D-aspartate receptor antagonism on neuroleptic-induced orofacial dyskinesias.
Topics: Allosteric Regulation; Amantadine; Animals; Antipsychotic Agents; Dextrorphan; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Haloperidol; Male; Phenols; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies.
Topics: Animals; Antipsychotic Agents; Binding Sites; Buffers; Ethanolamines; Haloperidol; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Oligopeptides; Oocytes; Piperidines; Protein Binding; Protein Refolding; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Xenopus | 2008 |
Influence of GIRK channel inhibition on alcohol abstinence and relapse risk in Japanese alcohol-dependent outpatients.
Topics: Alcoholism; Analysis of Variance; Asian People; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Haloperidol; Humans; Middle Aged; Outpatients; Paroxetine; Piperidines; Retrospective Studies; Risk; Secondary Prevention; Treatment Outcome | 2011 |
Sigma receptor ligands haloperidol and ifenprodil attenuate hypoxia induced dopamine release in rat striatum.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Hypoxia; Ligands; Nomifensine; Ouabain; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2022 |