Compounds > idra 21

idra 21 and cyclothiazide

idra 21 has been researched along with cyclothiazide in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baraldi, M; Braghiroli, D; Cannazza, G; Losi, G; Parenti, C; Puia, G; Tait, A1
Caignard, DH; Danober, L; Dintilhac, G; Fraikin, P; Francotte, P; Goffin, E; Graindorge, E; Lestage, P; Pirotte, B; Thomas, JY; Tullio, Pd1
Caignard, DH; Danober, L; de Tullio, P; Diouf, O; Fraikin, P; Francotte, P; Lestage, P; Pirotte, B; Podona, T; Thomas, JY1
Ahmed, AH; Oswald, RE1
Costa, E; Guidotti, A; Impagnatiello, F; Longone, P; Mienville, JM1
Covey, DF; Hill, MW; Hu, Y; Yamada, KA1
Arai, AC; Granger, R; Kessler, M; Kleisli, T; Krutzik, PO; Lynch, G; Phillips, D; Richard Chamberlin, A; Sonnenberg, J; Vaswani, R1
de Barrios, O; Francotte, P; Frydenvang, K; Gajhede, M; Kastrup, JS; Krintel, C; Kristensen, MT; Naur, P; Olsen, L; Pirotte, B1

Other Studies

8 other study(ies) available for idra 21 and cyclothiazide

ArticleYear
Synthesis of 3,4-dihydro-2H-1,2,4-benzo-thiadiazine 1,1-dioxide derivatives as potential allosteric modulators of AMPA/kainate receptors.
    Journal of medicinal chemistry, 2002, Jun-06, Volume: 45, Issue:12

    Topics: Allosteric Regulation; Animals; Benzothiadiazines; Cell Line; Cerebellum; Excitatory Amino Acid Agonists; Kainic Acid; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, Kainic Acid; Stereoisomerism; Structure-Activity Relationship

2002
Design, synthesis, and pharmacology of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors.
    Journal of medicinal chemistry, 2007, Jun-28, Volume: 50, Issue:13

    Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cognition; Cyclic S-Oxides; Drug Design; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Norepinephrine; Oocytes; Rats; Rats, Wistar; Receptors, AMPA; Recognition, Psychology; RNA, Messenger; Structure-Activity Relationship; Thiadiazines; Xenopus

2007
Synthesis and pharmacological evaluation of a second generation of pyridothiadiazine 1,1-dioxides acting as AMPA potentiators.
    Bioorganic & medicinal chemistry, 2008, Dec-01, Volume: 16, Issue:23

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diazoxide; Oocytes; Rats; Rats, Wistar; Receptors, AMPA; Solubility; Structure-Activity Relationship; Thiadiazines; Xenopus laevis

2008
Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Allosteric Regulation; Binding Sites; Humans; Mutagenesis, Insertional; Nootropic Agents; Piracetam; Pyrrolidinones; Receptors, AMPA; X-Ray Diffraction

2010
Changes in AMPA receptor-spliced variant expression and shift in AMPA receptor spontaneous desensitization pharmacology during cerebellar granule cell maturation in vitro.
    Journal of molecular neuroscience : MN, 1998, Volume: 11, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Benzothiadiazines; Calcium; Cell Differentiation; Cells, Cultured; Cerebellum; Electrophysiology; Gene Expression Regulation, Developmental; Ion Channels; Neurons; Nitrendipine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA Editing; Sodium

1998
The diazoxide derivative 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide augments AMPA- and GABA-mediated synaptic responses in cultured hippocampal neurons.
    Neurobiology of disease, 1998, Volume: 5, Issue:3

    Topics: Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neural Inhibition; Neurons; Neurotoxins; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Receptors, GABA; Synapses; Synaptic Transmission

1998
5'-alkyl-benzothiadiazides: a new subgroup of AMPA receptor modulators with improved affinity.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:5

    Topics: Animals; Benzothiadiazines; Brain; Combinatorial Chemistry Techniques; Kinetics; Neurons; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Structure-Activity Relationship; Sulfonamides

2002
Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2.
    The Biochemical journal, 2012, Jan-01, Volume: 441, Issue:1

    Topics: Benzothiadiazines; Calorimetry; Crystallization; Cyclic S-Oxides; Diuretics; Gene Expression Regulation; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Receptors, AMPA; Receptors, Ionotropic Glutamate; Thermodynamics; Thiadiazines

2012