Page last updated: 2024-08-17

idoxuridine and uracil

idoxuridine has been researched along with uracil in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199034 (79.07)18.7374
1990's6 (13.95)18.2507
2000's2 (4.65)29.6817
2010's1 (2.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bryan, AM; Lau, K; Olafsson, PG1
Voytek, P1
Halpern, A; Stöcklin, G1
Bleackley, RC; Jones, AS; Walker, RT1
Belotto, N; Canobbio, G; Lietti, F; Lucarelli, C; Magnani, P; Reiner, V; Verga, F1
Gati, WP; Iwashina, T; Knaus, EE; McQueen, L; Wiebe, LI1
Filov, VA; Onishchuk, FD; Tret'iakov, AV1
Hume, WJ; Saffhill, R1
Dobson, PP; Kinsella, TJ; Mitchell, JB1
Collins, JM; Fine, RL; Jenkins, JF; Kinsella, TJ; Klecker, RW; Strong, JM1
Fox, BW; Perkins, JP; Prusoff, WH1
Hanna, C1
Beck, A; Tan, YL1
Prusoff, WH; Sekely, L1
Hüttermann, J; Müller, A2
Bärwolff, D; Langen, P; Matthes, E1
Goz, B; Prusoff, WH1
Dixon, GJ; Schabel, FM; Sellers, SM; Sidwell, RW1
Etzold, G; Langen, P1
Byvoet, P; Clarkson, DR; Oppelt, WW1
Clough, DW; Edelhauser, HF; Geroski, DH; O'Brien, WJ1
Allegra, CJ; Grogan, L; Sotos, GA1
Berezin, F; Janisch, L; Mick, R; Ratain, MJ; Schilsky, RL; Vogelzang, NJ1
DeGoeij, K; Mester, J; Sluyser, M1
Asmann, PT; Duggan, LJ; Gottlieb, PA; Hill, TM1
Asao, T; Emura, T; Fukushima, M; Kazuno, H; Suzuki, N; Tada, Y; Yamada, Y; Yano, S1
Nikjoo, H; Watanabe, R1
BENUA, RS; CHEONG, L; EIDINOFF, ML; ELLISON, RR; GURPIDE, EG1
GUNTHER, HL; PRUSOFF, WH1
SILVESTER, DJ; WHITE, ND1
ENGLE, CG; STEWART, RC1
BOND, SB; KRISS, JP1
STEPANIK, J1
HOFFMANN, DH; SEEGER, E1
REIM, M1
PRUSOFF, WH; RUPP, WD1
HOFFMANN, DH1
RAVIN, IJ; SIMPSON, CA; ZAPPALA, AF1
ARITA, T; HASHI, M; KAKEMI, K1
KOCH, P1
BUI, NM; DUMONT, P; GILLET, R1
Alcolea Palafox, M1

Reviews

3 review(s) available for idoxuridine and uracil

ArticleYear
Chemical and biological consequences of beta-decay. Part 1.
    Radiation and environmental biophysics, 1977, Oct-12, Volume: 14, Issue:3

    Topics: Bromodeoxyuridine; Carbon Radioisotopes; Cytosine; Deoxyuridine; Free Radicals; Idoxuridine; Iodine Radioisotopes; Isotope Labeling; Phenols; Phosphorus Radioisotopes; Radioactive Tracers; Radioactivity; Radioisotopes; Succinates; Sulfur Radioisotopes; Thymidine; Tritium; Tyrosine; Uracil

1977
Pharmacology of viruses.
    Annual review of pharmacology, 1970, Volume: 10

    Topics: Amantadine; Animals; Antiviral Agents; Chick Embryo; Cytarabine; Fluorouracil; Guanidines; Haplorhini; Humans; Idoxuridine; Interferons; Nucleosides; Receptors, Drug; Rifampin; RNA, Transfer; RNA, Viral; Uracil; Viral Proteins; Virus Diseases; Viruses

1970
Preclinical and clinical aspects of biomodulation of 5-fluorouracil.
    Cancer treatment reviews, 1994, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine

1994

Trials

1 trial(s) available for idoxuridine and uracil

ArticleYear
Phase I clinical and pharmacological study of iododeoxyuridine and bleomycin in patients with advanced cancer.
    Cancer research, 1993, Mar-15, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Female; Humans; Idoxuridine; Male; Middle Aged; Neoplasms; Uracil

1993

Other Studies

39 other study(ies) available for idoxuridine and uracil

ArticleYear
A differential scanning calorimetric-thin-layer chromatographic study of 5-halo-2'-deoxynucleosides.
    Journal of chromatography, 1976, Sep-15, Volume: 124, Issue:2

    Topics: Bromodeoxyuridine; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Deoxyuridine; Floxuridine; Idoxuridine; Uracil

1976
Purification of thymidine phosphorylase from Escherichia coli and its photoinactivation in the presence of thymine, thymidine, and some halogenated analogs.
    The Journal of biological chemistry, 1975, May-25, Volume: 250, Issue:10

    Topics: Bromodeoxyuridine; Bromouracil; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Hydrogen-Ion Concentration; Idoxuridine; Isoelectric Focusing; Kinetics; Pentosyltransferases; Photochemistry; Thymidine; Thymidine Phosphorylase; Thymine; Time Factors; Uracil

1975
The preparation of 5-cyanouracil and 5-cyano-2'-deoxyuridine from the corresponding 5-iodo derivative and cuprous cyanide.
    Nucleic acids research, 1975, Volume: 2, Issue:5

    Topics: Chemical Phenomena; Chemistry; Coliphages; Cyanides; Deoxyuridine; DNA, Bacterial; DNA, Viral; Escherichia coli; Idoxuridine; Mycoplasma mycoides; Nitriles; Structure-Activity Relationship; Uracil

1975
Determination of 2'-deoxy-5-iodouridine and its metabolite 5-iodouracil by high-performance liquid chromatography with ultraviolet absorbance detection in human serum.
    Journal of chromatography, 1991, Dec-06, Volume: 572, Issue:1-2

    Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Humans; Idoxuridine; Reference Values; Spectrophotometry, Ultraviolet; Uracil

1991
Drug-induced perturbations in the in vivo distribution of oncological radiotracers--II. 5-[125I]iodo-2'-deoxyuridine influenced by nitrobenzylthioinosine-5'-phosphate (NBMPR-P) and acyclothymidine (ACT).
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1990, Volume: 41, Issue:2

    Topics: Animals; Idoxuridine; Inosine; Iodine Radioisotopes; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Radionuclide Imaging; Stimulation, Chemical; Thioinosine; Thionucleotides; Tissue Distribution; Uracil

1990
[Toxicity of para-aminobenzhydrazide and its influence on nucleic acid biosynthesis in cultures of normal and tumor cells].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 107, Issue:2

    Topics: Aniline Compounds; Animals; Cells, Cultured; DNA; DNA, Neoplasm; Humans; Idoxuridine; Lymphocyte Activation; Lymphocytes; Papio; RNA; RNA, Neoplasm; Time Factors; Tumor Cells, Cultured; Uracil

1989
The degradation of 5-iododeoxyuridine and 5-bromodeoxyuridine by serum from different sources and its consequences for the use of the compounds for incorporation into DNA.
    Chemico-biological interactions, 1986, Volume: 57, Issue:3

    Topics: Animals; Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Deoxyuridine; DNA; Horses; Idoxuridine; Male; Mice; Rabbits; Species Specificity; Thyroid Gland; Uracil

1986
Interaction of iododeoxyuridine and its primary metabolite, iodouracil on radiation response.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:8

    Topics: Animals; Cell Division; Cell Survival; Cricetinae; Idoxuridine; In Vitro Techniques; Uracil

1986
Clinical pharmacology of 5-iodo-2'-deoxyuridine and 5-iodouracil and endogenous pyrimidine modulation.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:1

    Topics: Chromatography, High Pressure Liquid; Deoxyuridine; Humans; Idoxuridine; Infusions, Parenteral; Neoplasms; Thymine; Uracil; Uridine

1985
Inhibitory action of thymine ribonucleoside and other pyrimidine derivatives on the cleavage of 5-iodo-deoxy-uridine by mouse-liver extract.
    Chemico-biological interactions, 1970, Volume: 1, Issue:4

    Topics: Animals; Chromatography, Thin Layer; Deoxyribonucleosides; Depression, Chemical; Female; Floxuridine; Hydrogen-Ion Concentration; Idoxuridine; Iodine Isotopes; Kinetics; Liver; Mice; Nucleosides; Pentosyltransferases; Pyrimidines; Rats; Ribonucleosides; Thymidine; Thymine; Uracil; Uridine

1970
Incorporation of idoxuridine analogs into corneal herpes simplex virus.
    Annals of ophthalmology, 1972, Volume: 4, Issue:11

    Topics: Animals; Autoradiography; Bromodeoxyuridine; Cornea; DNA, Viral; Epithelium; Floxuridine; Fluorouracil; Herpes Simplex; Idoxuridine; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Thymidine; Tritium; Uracil

1972
Complex formation of uracil, 2'-deoxyuridine and their 5-halogenated derivatives.
    Biochimica et biophysica acta, 1973, Apr-11, Volume: 299, Issue:4

    Topics: Bromodeoxyuridine; Bromouracil; Chemical Phenomena; Chemistry; Copper; Deoxyuridine; Drug Stability; Floxuridine; Fluorouracil; Idoxuridine; Mathematics; Nickel; Potentiometry; Silver; Uracil

1973
Anti-viral activity of azathymidine and uracil methyl sulphone.
    Nature, 1966, Sep-17, Volume: 211, Issue:5055

    Topics: Animals; Antiviral Agents; Carbon Isotopes; Chick Embryo; Fibroblasts; Idoxuridine; Nucleosides; Simplexvirus; Sulfones; Time; Triazines; Uracil

1966
Free radicals in irradiated single crystals of 5-halo-uracil derivatives: 5-bromouracil, 5-bromodeoxyuridine and 5-iododeoxyuridine.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1969, Volume: 15, Issue:4

    Topics: Chemical Phenomena; Chemistry; Computers; Crystallization; Deoxyuridine; Electron Spin Resonance Spectroscopy; Free Radicals; Idoxuridine; Radiation Effects; Uracil

1969
Structure and formation of free radicals in irradiated single crystals of nucleic acid constituents.
    Annals of the New York Academy of Sciences, 1973, Dec-31, Volume: 222

    Topics: Adenine; Barbiturates; Bromodeoxyuridine; Crystallization; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Idoxuridine; Molecular Conformation; Orotic Acid; Purines; Pyrimidines; Radiation Effects; Structure-Activity Relationship; Thymine; Uracil

1973
Inhibition by 6-aminothymine of the degradation of nucleosides (5-iododeoxyuridine, thymidine) and pyrimidine bases (5-iodouracil, uracil and 5-fluorouracil) in vivo.
    Acta biologica et medica Germanica, 1974, Volume: 32, Issue:5

    Topics: Amines; Animals; Antimetabolites; Bone Marrow; Chromatography; DNA; Fluorouracil; Idoxuridine; Intestinal Mucosa; Iodine Radioisotopes; Male; Mice; Nucleosides; Pentosyltransferases; Rabbits; Spleen; Thymidine; Thymine; Thymus Gland; Uracil

1974
In vivo antiviral properties of biologically active compounds. II. Studies with influenza and vaccinia viruses.
    Applied microbiology, 1968, Volume: 16, Issue:2

    Topics: Alkylating Agents; Amantadine; Anti-Bacterial Agents; Antimetabolites; Antiviral Agents; Guanidines; Hormones; Idoxuridine; Orthomyxoviridae; Semicarbazides; Uracil; Vaccinia virus

1968
Enhancement by deoxyglucosyl-thymine of the 5-iododeoxyuridine incorporation into DNA in vivo at high doses of 5-iododeoxyuridine.
    Acta biologica et medica Germanica, 1966, Volume: 17, Issue:3

    Topics: Animals; Antimetabolites; Bone Marrow; Bone Marrow Cells; Cats; DNA; Glucosyltransferases; Idoxuridine; Intestinal Mucosa; Spleen; Thymidine; Uracil

1966
The fate of 5-iodo-2'-deoxyuridine (IUdR) in plasma and cerebrospinal fluid of dogs.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:3

    Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Dogs; Idoxuridine; Iodine Isotopes; Tritium; Uracil

1967
Effects of nucleoside antivirals and their metabolites on the corneal endothelium.
    Current eye research, 1981, Volume: 1, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; Cornea; Deoxyuridine; Endothelium; Fluorides; Guanine; Idoxuridine; In Vitro Techniques; Rabbits; Thymine Nucleotides; Uracil

1981
Modulation of [5-125I]iododeoxyuridine incorporation into tumour and normal tissue DNA by methotrexate and thymidylate synthase inhibitors.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Female; Fluorouracil; Idoxuridine; Intestine, Small; Iodine Radioisotopes; Liver; Mammary Neoplasms, Experimental; Methotrexate; Mice; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Quinazolines; Thiophenes; Thymidylate Synthase; Uracil

1996
Identification of a Tus protein segment that photo-cross-links with TerB DNA and elucidation of the role of certain thymine methyl groups in the Tus-TerB complex using halogenated uracil analogues.
    Biochemistry, 1996, Dec-03, Volume: 35, Issue:48

    Topics: Bacterial Proteins; Bromodeoxyuridine; DNA; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Glutamates; Half-Life; Idoxuridine; Thymine; Uracil

1996
Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2'-deoxyribonucleosides.
    Biochemical pharmacology, 2000, May-15, Volume: 59, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Dogs; Drug Synergism; Enzyme Inhibitors; Female; Humans; Idoxuridine; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Placenta; Pyrrolidines; Recombinant Proteins; Structure-Activity Relationship; Thymidine; Thymidine Phosphorylase; Trifluridine; Uracil

2000
Modelling the effect of incorporated halogenated pyrimidine on radiation-induced DNA strand breaks.
    International journal of radiation biology, 2002, Volume: 78, Issue:11

    Topics: Base Sequence; Bromodeoxyuridine; Chromosome Breakage; Computer Simulation; DNA; DNA Damage; Dose-Response Relationship, Radiation; Free Radicals; Idoxuridine; Linear Energy Transfer; Models, Chemical; Models, Molecular; Molecular Sequence Data; Monte Carlo Method; Radiation Tolerance; Uracil; Water

2002
Incorporation of 5-iodouracil labelled with iodine-131 into the deoxyribonucleic acid of human leukaemic leucocytes following in vivo administration of 5-iododeoxyuridine labelled with iodine-131.
    Nature, 1959, Jun-13, Volume: 183, Issue:4676

    Topics: DNA; Idoxuridine; Iodine; Leukemia; Leukocytes; Nucleosides; Nucleotides; Uracil

1959
Studies of the mechanism of resistance to pyrimidines in Streptococcus faecalis. I. An unusual effect of 5-iodouracil and 5-iodo-2'-deoxyuridine.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Enterococcus faecalis; Idoxuridine; Nucleosides; Pyrimidines; Uracil

1963
PREPARATION OF VERY HIGH SPECIFIC ACTIVITY IODODEOXYURIDINE, IODOURIDINE AND IODOURACIL, LABELLED WITH IODINE-125, -131 OR -132.
    Nature, 1963, Oct-05, Volume: 200

    Topics: Idoxuridine; Iodine; Iodine Isotopes; Nucleosides; Radioisotopes; Radionuclide Imaging; Research; Toxicology; Uracil

1963
ANTI-HERPETIC ACTIVITY OF 5-IODO-2'-DEOXYURIDINE IN PRESENCE OF ITS DEGRADATION PRODUCTS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Chick Embryo; Deoxyuridine; Idoxuridine; Kidney; Nucleosides; Pharmacology; Pyrimidines; Rabbits; Research; Simplexvirus; Tissue Culture Techniques; Uracil; Virus Cultivation

1964
THE EFFECT OF NATURAL AND UNNNATURAL PYRIMIDINES AND PYRIMIDINE NUCLEOSIDES ON THE PHOSPHOROLYSIS OF 5-IODODEOXYURIDINE BY MOUSE LIVER EXTRACT.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Chromatography; Deoxyuridine; Floxuridine; Fluorouracil; Idoxuridine; Iodine Isotopes; Liver; Liver Extracts; Metabolism; Mice; Nucleosides; Pharmacology; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Research; Thymidine; Thymine; Uracil

1964
[THE CLINICAL COURSE OF HERPES SIMPLEX CORNEAE UNDER TREATMENT WITH IODOURACIL DESOXYRIBOSIDE].
    Klinische Monatsblatter fur Augenheilkunde, 1964, Volume: 144

    Topics: Cornea; Herpes Simplex; Humans; Idoxuridine; Keratitis; Keratitis, Dendritic; Ophthalmic Solutions; Uracil

1964
[STUDIES ON THE EFFECT OF IODOURACIL-DESOXYRIBOSIDE (IUDR) ON THE EXPERIMENTAL HERPES SIMPLEX KERATITIS IN RABBITS].
    Klinische Monatsblatter fur Augenheilkunde, 1964, Volume: 144

    Topics: Animals; Idoxuridine; Keratitis; Keratitis, Dendritic; Keratitis, Herpetic; Ophthalmic Solutions; Rabbits; Research; Uracil

1964
[EXPERIENCES WITH THE USE AND STABILITY OF 5-IODOURACIL DESOXYRIBOSIDE (IUDR)].
    Klinische Monatsblatter fur Augenheilkunde, 1964, Volume: 144

    Topics: Idoxuridine; Keratitis; Keratitis, Dendritic; Ophthalmic Solutions; Uracil

1964
INCORPORATION OF 5-IODO-2'-DEOXYURIDINE INTO BACTERIOPHAGE T1 AS RELATED TO ULTRA-VIOLET SENSITIZATION OR PROTECTION.
    Nature, 1964, Jun-27, Volume: 202

    Topics: Coliphages; Cysteamine; DNA; DNA, Viral; Idoxuridine; Metabolism; Mutation; Pharmacology; Radiation Effects; Research; Ultraviolet Rays; Uracil; Viola

1964
[PRELIMINARY EXPERIENCES WITH IODOURACIL DESOXYRIBOSIDE (IUDR) IN THE TREATMENT OF HERPETIC CORNEAL DISEASES].
    Klinische Monatsblatter fur Augenheilkunde, 1964, Volume: 144

    Topics: Adrenal Cortex Hormones; Corneal Diseases; Humans; Idoxuridine; Keratitis; Keratitis, Dendritic; Ointments; Uracil

1964
IDOXURIDINE--A PRELIMINARY REPORT.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Chemistry, Pharmaceutical; Idoxuridine; Nucleosides; Pharmacy; Pyrimidines; Research; Ribose; Uracil

1964
[SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF 5-IODO-2'-DEOXYURIDINE AND 5-IODOURACIL].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1964, Volume: 84

    Topics: Chemistry, Pharmaceutical; Deoxyuridine; Idoxuridine; Pharmacy; Research; Spectrophotometry; Uracil

1964
[EXPERIENCES WITH THE VIROSTATIC IODOURACIL DESOXYRIBOSIDE (IUDR) IN HERPES DISEASES OF THE EYE].
    Klinische Monatsblatter fur Augenheilkunde, 1965, Volume: 146

    Topics: Drug Therapy; Eye; Herpes Zoster; Herpes Zoster Ophthalmicus; Humans; Idoxuridine; Keratitis; Keratitis, Dendritic; Uracil

1965
AN IMPROVED SYNTHESIS OF 5-IODO-2'-DEOXYURIDINE-I-131 AND 5-IODOURACIL-I-131.
    The International journal of applied radiation and isotopes, 1965, Volume: 16

    Topics: Chemistry Techniques, Analytical; Idoxuridine; Iodine; Iodine Isotopes; Radioisotopes; Research; Uracil; Uracil Nucleotides

1965
Molecular structure differences between the antiviral Nucleoside Analogue 5-iodo-2'-deoxyuridine and the natural nucleoside 2'-deoxythymidine using MP2 and DFT methods: conformational analysis, crystal simulations, DNA pairs and possible behaviour.
    Journal of biomolecular structure & dynamics, 2014, Volume: 32, Issue:5

    Topics: Antiviral Agents; Crystallography, X-Ray; DNA; Hydrogen Bonding; Idoxuridine; Models, Molecular; Molecular Conformation; Molecular Structure; Ribose; Thermodynamics; Thymidine; Uracil

2014