Page last updated: 2024-08-17

idoxuridine and methotrexate

idoxuridine has been researched along with methotrexate in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199020 (68.97)18.7374
1990's3 (10.34)18.2507
2000's4 (13.79)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Gajcy, H; Koziorowska, J; Pieńkowska, K; Tautt, J1
Boone, C; Liotta, LA; Saini, RK; Vembu, D1
Santi, DV; Wataya, Y1
Bruckner, HW; Schreiber, C; Waxman, S1
Anderson, D1
Antoniw, P; Bagshawe, KD; Boden, JA; Boxer, GM; Patridge, TA; Pedley, RB; Sharma, K; Southall, PJ1
Benedict, WF; Heidelberger, C; Peterson, AR1
Bagshawe, KD; Boden, J; Boxer, GM; Britton, DW; Green, A; Partridge, T; Pedley, B; Sharma, S; Southall, P1
Fischer, PH; Reznikoff, CA; Vazquez-Padua, MA1
Houlihan, RB; Roby, R; Teskey, C1
Cassidy, EP; Fischer, DS; Welch, AD1
Rizki, RM; Rizki, TM1
Fischer, GA1
Fox, M1
Hofer, KG; Hughes, WL; Prensky, W; Rosenoff, S1
Andrýsek, O; Dvorák, O; Stránská, E1
Hsu, TC; Humphrey, RM1
Jacobs, EM; Johnson, FD; Wood, DA1
Allegra, CJ; Grogan, L; Sotos, GA1
DeGoeij, K; Mester, J; Sluyser, M1
Adelstein, SJ; Dahman, BA; Kassis, AI1
COLEMAN, V; CORWIN, ME; JAWETZ, E; OKUMOTO, M; RIEGELMAN, S; THYGESON, P1
FISCHER, GA; VONESSEN, CF1
du Plessis, J; Du Preez, J; Hadgraft, J; Ita, KB; Lane, ME1
Adelstein, SJ; Artignan, X; Balosso, J; Desruet, MD; Fagret, D; Gauchez, AS; Hoffmann, D; Kassis, AI; Rebischung, C; Stefani, L; Vincent, F; Vuillez, J; Wang, K; Zhang, H1

Reviews

3 review(s) available for idoxuridine and methotrexate

ArticleYear
Radiation sensitizers.
    Cancer, 1976, Volume: 37, Issue:4 Suppl

    Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs; Dose-Response Relationship, Radiation; Floxuridine; Humans; Hypoxia; Idoxuridine; Lung Neoplasms; Methotrexate; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Research; Sarcoma, Experimental; Skin

1976
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
    Basic life sciences, 1985, Volume: 31

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine

1985
Preclinical and clinical aspects of biomodulation of 5-fluorouracil.
    Cancer treatment reviews, 1994, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine

1994

Other Studies

26 other study(ies) available for idoxuridine and methotrexate

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
On the combined action of drugs on the lambda prophage induction in Escherichia coli K12 cells.
    Acta microbiologica Polonica, 1977, Volume: 26, Issue:1

    Topics: Coliphages; Drug Synergism; Escherichia coli; Fluorouracil; Idoxuridine; Methotrexate; Virus Replication

1977
In vivo monitoring of the death rate of artificial murine pulmonary micrometastases.
    Cancer research, 1978, Volume: 38, Issue:5

    Topics: Animals; Cell Survival; Connective Tissue Cells; Idoxuridine; Iodine Radioisotopes; Lung Neoplasms; Methotrexate; Mice; Neoplasm Metastasis; Sarcoma, Experimental

1978
Thymidylate synthetase catalyzed dehalogenation of 5-bromo-and 5-iodo-2'-deoxyuridylate.
    Biochemical and biophysical research communications, 1975, Nov-17, Volume: 67, Issue:2

    Topics: Bromodeoxyuridine; Drug Resistance, Microbial; Idoxuridine; Lacticaseibacillus casei; Methotrexate; Methyltransferases; Spectrophotometry, Ultraviolet; Thymidylate Synthase; Uracil Nucleotides

1975
Interaction of chemotherapeutic agents with methotrexate and 5-fluorouracil and its effect on de novo DNA synthesis.
    Cancer research, 1975, Volume: 35, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cephalosporins; Dexamethasone; DNA; DNA, Neoplasm; Fluorouracil; Folic Acid; Glucocorticoids; Humans; Hydrocortisone; Idoxuridine; In Vitro Techniques; Leukemia L1210; Methotrexate; Mice; Mice, Inbred DBA; Prednisolone; Prednisone; Vincristine

1975
Attempts to produce systems for isolating spontaneous and induced variants in various mouse lymphoma cells using a varity of selective agents.
    Mutation research, 1975, Volume: 33, Issue:2-3

    Topics: Animals; Azaguanine; Cell Line; Cell Survival; Genetic Variation; Idoxuridine; Lymphoma; Methotrexate; Mice; Mutagens; Mutation; Selection, Genetic; Time Factors

1975
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
    The British journal of radiology, 1991, Volume: 64, Issue:757

    Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resistance; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Iodine Radioisotopes; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Uterine Neoplasms

1991
A cytotoxic DNA precursor is taken up selectively by human cancer xenografts.
    British journal of cancer, 1987, Volume: 55, Issue:3

    Topics: Animals; Choriocarcinoma; Colon; DNA; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Nucleic Acid Precursors; Pregnancy; Uterine Neoplasms

1987
Perturbation of thymidine kinase regulation: a novel chemotherapeutic approach.
    Advances in enzyme regulation, 1986, Volume: 25

    Topics: Cell Division; Cell Survival; Cells, Cultured; Humans; Idoxuridine; Methotrexate; Thymidine; Thymidine Kinase; Thymine Nucleotides; Ureter; Urinary Bladder

1986
Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 120, Issue:2

    Topics: Antiviral Agents; Benzimidazoles; Bromodeoxyuridine; Culture Techniques; Cytosine; DNA, Viral; Fibroma; Floxuridine; Fluorouracil; Idoxuridine; Mercaptopurine; Methotrexate; Myxoma virus; Nucleosides; Oncogenic Viruses; Thiosemicarbazones; Thymine

1965
Immunosuppression by pyrimidine nucleoside analogs.
    Biochemical pharmacology, 1966, Volume: 15, Issue:8

    Topics: Animals; Antibody Formation; Antimetabolites; Azathioprine; Bromodeoxyuridine; Chloramphenicol; Cytarabine; Cytosine Nucleotides; Erythrocytes; Floxuridine; Hemagglutination Tests; Idoxuridine; Injections, Intraperitoneal; Injections, Subcutaneous; Mercaptoethanol; Mercaptopurine; Methotrexate; Mice; Nucleosides; Sheep

1966
The role of thymidylate synthetase inhibitors in bromodeoxyuridine-induced neoplasia in Drosophila.
    Cancer research, 1973, Volume: 33, Issue:11

    Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA; Drosophila; Fluorine; Fluorouracil; Idoxuridine; Larva; Methotrexate; Methyltransferases; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Tritium

1973
Predictive tests in culture of drug-resistant mutants selected in vivo.
    National Cancer Institute monograph, 1971, Volume: 34

    Topics: Animals; Antineoplastic Agents; Biological Assay; Cell Line; Clone Cells; Cytarabine; Drug Resistance; Idoxuridine; Leukemia, Experimental; Methods; Methotrexate; Mice; Mice, Inbred Strains; Molecular Biology; Mutagens; Mutation; Prognosis

1971
Spontaneous and x-ray-induced genotypic and phenotypic resistance to 5-iodo-2'-deoxyuridine in lymphoma cells in vitro.
    Mutation research, 1971, Volume: 13, Issue:4

    Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Drug Resistance; Genotype; Hypoxanthines; Idoxuridine; Lymphoma; Methotrexate; Mice; Mutation; Phenotype; Radiation Dosage; Radiation Genetics; Thymidine; Time Factors

1971
Spontaneous and amethopterin-induced death of L1210 leukaemia cells in vivo.
    Nature, 1969, Feb-08, Volume: 221, Issue:5180

    Topics: Animals; DNA, Neoplasm; Idoxuridine; Injections, Intramuscular; Injections, Intraperitoneal; Iodine Radioisotopes; Leukemia L1210; Methotrexate; Mice

1969
[The possibility of selective chemotherapy of progressive recurring ovarian carcinoma with the aid of cytodiagnosis and incorporation of tagged idoxuridine].
    Geburtshilfe und Frauenheilkunde, 1969, Volume: 29, Issue:7

    Topics: Aged; Antineoplastic Agents; Ascites; Cyclophosphamide; Cytodiagnosis; Female; Humans; Idoxuridine; Iodine Isotopes; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplastic Cells, Circulating; Ovarian Neoplasms; Time Factors

1969
Further studies on biological properties of mammalian cell lines resistant to 5-bromodeoxyuridine.
    Texas reports on biology and medicine, 1965, Volume: 23

    Topics: Animals; Bromodeoxyuridine; Chromosomes; Cricetinae; DNA; Fibroblasts; Idoxuridine; Methotrexate; Mice; Thymidine; Thymidine Kinase; Tritium

1965
Stage 3 metastatic malignant testicular tumors. Treatment with intermittent and combined chemotherapy.
    Cancer, 1966, Volume: 19, Issue:11

    Topics: Adult; Dactinomycin; Dysgerminoma; Humans; Idoxuridine; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Metastasis; Teratoma; Testicular Neoplasms; Vincristine

1966
Modulation of [5-125I]iododeoxyuridine incorporation into tumour and normal tissue DNA by methotrexate and thymidylate synthase inhibitors.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Female; Fluorouracil; Idoxuridine; Intestine, Small; Iodine Radioisotopes; Liver; Mammary Neoplasms, Experimental; Methotrexate; Mice; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Quinazolines; Thiophenes; Thymidylate Synthase; Uracil

1996
In vivo therapy of neoplastic meningitis with methotrexate and 5.
    Acta oncologica (Stockholm, Sweden), 2000, Volume: 39, Issue:6

    Topics: Animals; Electrons; Humans; Idoxuridine; Injections, Spinal; Iodine Radioisotopes; Meningitis; Methotrexate; Nucleic Acid Synthesis Inhibitors; Paralysis; Radiopharmaceuticals; Rats; Rats, Nude; Rhabdomyosarcoma; S Phase; Spinal Cord; Tissue Distribution

2000
EFFECT OF IUDR AND AMETHOPTERIN ON EXPERIMENTAL HERPES SIMPLEX KERATITIS.
    Investigative ophthalmology, 1963, Volume: 2

    Topics: Animals; Fluoresceins; Idoxuridine; Keratitis; Keratitis, Dendritic; Keratitis, Herpetic; Lagomorpha; Methotrexate; Pharmacology; Rabbits; Research; Tissue Culture Techniques

1963
THE COMPARISON OF RADIATION AND ANTIMETABOLITE RESPONSES OF GENETICALLY ALTERED MURINE LEUKEMIC CELLS.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Animals; Antimetabolites; Chromosomes; Floxuridine; Genetics; Idoxuridine; Leukemia; Leukemia, Experimental; Mast Cells; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimethamine; Radiation Genetics; Research; Tissue Culture Techniques

1965
Dermal delivery of selected hydrophilic drugs from elastic liposomes: effect of phospholipid formulation and surfactants.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:9

    Topics: Acyclovir; Administration, Cutaneous; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Diffusion; Elasticity; Epidermis; Humans; Idoxuridine; Liposomes; Methotrexate; Microscopy, Electron, Transmission; Particle Size; Permeability; Phosphatidylcholines; Phospholipids; Skin; Skin Absorption; Structure-Activity Relationship; Surface-Active Agents

2007
First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR.
    International journal of radiation biology, 2008, Volume: 84, Issue:12

    Topics: Adult; Antibiotics, Antineoplastic; Antigens, Tumor-Associated, Carbohydrate; Brain Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Idoxuridine; Injections, Spinal; Iodine Radioisotopes; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Radiopharmaceuticals

2008