Page last updated: 2024-08-17

idoxuridine and ganciclovir

idoxuridine has been researched along with ganciclovir in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's7 (26.92)18.2507
2000's11 (42.31)29.6817
2010's1 (3.85)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Andrei, G; Balzarini, J; Claes, P; De Clercq, E; Rozenski, J; Snoeck, R; Van Aerschot, A; Van Meervelt, L; Verheggen, I; Wiebe, L1
Andrei, G; De Clercq, E; Golankiewicz, B; Ostrowski, T; Snoeck, R1
Balzarini, J; De Clercq, E; Herdewijn, P; Janssen, G; Snoeck, R; Toppet, S; Van Aerschot, A; Verheggen, I1
Clercq, ED; Folkers, G; Marquez, VE; Russ, P; Scapozza, L; Schelling, P1
Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE1
Ahn, H; An, GI; Cheon, GJ; Choi, TH; Chun, KS; De Castro, K; Hong, SH; Kim, B; Lee, JC; Lee, KC; Lim, SM; Moon, BS; Rhee, H1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Daily, SL; Frederick, SL; Harden, EA; Hartline, CB; Jefferson, G; Kern, ER; Maddry, JA; Prichard, MN; Quenelle, DC; Secrist, JA; Tiwari, KN; Whitley, RJ1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Domin, BA; Mahony, WB; Zimmerman, TP1
Charles, SJ; Gray, JJ1
Inoue, Y; Kato, S; Manabe, R; Ohashi, Y; Shimomura, Y; Ueda, S; Yamada, M1
Naito, T1
Coen, DM; Fleming, HE; Leslie, LK; Retondo, MJ1
Cockerill, FR; Hermans, PE1
Nesburn, AB; Taaid, H; Trousdale, MD; Willey, DE1
Johansson, NG; Oberg, B1
Blasberg, RG; Desai, R; Gansbacher, B; Stockhammer, G; Tjuvajev, JG; Uehara, H; Watanabe, K1
De Clercq, E; Kodama, E; Shigeta, S; Suzuki, T1
LaBree, L; McDonnell, PJ; Moreira, LB; Oliveira, C; Seitz, B1
Clarke, HE; Maggs, DJ1
Labetoulle, M1
Dediulescu, DF; Dediulescu, L1
Andronova, VL; Galegov, GA; Malinovskaya, VV; Vyzhlova, EN1
Cheon, GJ; Choi, CW; Choi, TH; Chung, WS; Jang, SJ; Kang, JH; Kim, KI; Kwon, HC; Lee, KC; Lee, TS; Lee, YJ; Lim, SM; Ryu, CJ; Woo, KS1

Reviews

3 review(s) available for idoxuridine and ganciclovir

ArticleYear
The relative merits and drawbacks of new nucleoside analogues with clinical potential.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 14 Suppl A

    Topics: Acyclovir; Animals; Antiviral Agents; Biotransformation; Bromodeoxyuridine; Cytarabine; DNA-Directed RNA Polymerases; Ganciclovir; Humans; Idoxuridine; Nucleic Acid Synthesis Inhibitors; Nucleic Acids; Nucleosides; Ribavirin; Trifluridine; Vidarabine; Viruses

1984
[The latest in herpes simplex keratitis therapy].
    Journal francais d'ophtalmologie, 2004, Volume: 27, Issue:5

    Topics: Acyclovir; Antiviral Agents; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Trifluridine

2004
[Antiherpetic therapy].
    Oftalmologia (Bucharest, Romania : 1990), 2005, Volume: 49, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Drug Combinations; Famciclovir; Foscarnet; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Oligonucleotides; Ophthalmic Solutions; Organophosphonates; Treatment Outcome; Valacyclovir; Valine; Vidarabine

2005

Other Studies

23 other study(ies) available for idoxuridine and ganciclovir

ArticleYear
Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.
    Journal of medicinal chemistry, 1995, Mar-03, Volume: 38, Issue:5

    Topics: Animals; Antiviral Agents; Biological Transport; Cells, Cultured; Crystallography, X-Ray; Cytopathogenic Effect, Viral; Herpesviridae; Humans; Male; Mice; Models, Molecular; Molecular Conformation; Nucleosides; RNA Viruses; Structure-Activity Relationship; Sugar Alcohols

1995
Tricyclic analogues of acyclovir and ganciclovir. Influence of substituents in the heterocyclic moiety on the antiviral activity.
    Journal of medicinal chemistry, 1994, Sep-16, Volume: 37, Issue:19

    Topics: Acyclovir; Antiviral Agents; Ganciclovir; Microbial Sensitivity Tests; Structure-Activity Relationship

1994
Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.
    Journal of medicinal chemistry, 1993, Jul-09, Volume: 36, Issue:14

    Topics: Antiviral Agents; Humans; Nucleosides; Simplexvirus; Structure-Activity Relationship; Tumor Cells, Cultured

1993
Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.
    Journal of medicinal chemistry, 2003, Nov-06, Volume: 46, Issue:23

    Topics: Antiviral Agents; Cell Division; Cell Line; Cell Line, Tumor; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Kinetics; Molecular Conformation; Poxviridae; Pyrimidine Nucleosides; Structure-Activity Relationship; Thymidine Kinase; Thymine; Vaccinia virus; Viral Plaque Assay

2003
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells

2007
Synthesis and evaluation of cis-1-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-5-[(124)I]iodouracil: a new potential PET imaging agent for HSV1-tk expression.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Animals; Cell Line, Tumor; Herpesvirus 1, Human; In Vitro Techniques; Iodine Radioisotopes; Mice; Mice, Nude; Microsomes, Liver; Positron-Emission Tomography; Radiopharmaceuticals; Serum; Thymidine Kinase; Tissue Distribution; Uridine

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Animals; Antiviral Agents; Cell Line; Cell Proliferation; Cells, Cultured; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Fluorescent Antibody Technique, Indirect; Herpesviridae; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Molecular Structure; Pyrimidine Nucleosides; Viral Proteins; Virus Replication

2009
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Ganciclovir permeation of the human erythrocyte membrane.
    Biochemical pharmacology, 1991, Jan-15, Volume: 41, Issue:2

    Topics: Acyclovir; Adenine; Biological Transport; Carrier Proteins; Cell Membrane Permeability; Dilazep; Dose-Response Relationship, Drug; Erythrocyte Membrane; Ganciclovir; Humans; Idoxuridine; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Purines

1991
Ocular herpes simplex virus infections: reduced sensitivity to acyclovir in primary disease.
    The British journal of ophthalmology, 1990, Volume: 74, Issue:5

    Topics: Acyclovir; Antiviral Agents; Foscarnet; Ganciclovir; Humans; Idoxuridine; Keratitis, Dendritic; Microbial Sensitivity Tests; Phosphonoacetic Acid; Simplexvirus; Vidarabine

1990
Comparative efficacy of three antiviral drugs in mice herpetic keratitis.
    Japanese journal of ophthalmology, 1989, Volume: 33, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Cells, Cultured; Female; Ganciclovir; Humans; Idoxuridine; Keratitis, Dendritic; Mice; Mice, Inbred BALB C; Ointments; Ophthalmic Solutions; Simplexvirus; Therapeutic Equivalency

1989
[Studies on the interaction of interferon with anti-herpetic agents].
    Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:7

    Topics: Acyclovir; Antiviral Agents; Drug Synergism; Ganciclovir; Humans; Idoxuridine; Interferon Type I; Simplexvirus

1988
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus.
    Journal of virology, 1985, Volume: 53, Issue:2

    Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Bromodeoxyuridine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Idoxuridine; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Vidarabine

1985
Antiviral agents.
    Mayo Clinic proceedings, 1987, Volume: 62, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Amantadine; Antiviral Agents; Ganciclovir; Herpes Simplex; Humans; Idoxuridine; Influenza A virus; Influenza, Human; Ribavirin; Rimantadine; Thymidine; Vidarabine; Viruses; Zidovudine

1987
Efficacy of BW759 (9-[[2-hydroxy-1(hydroxymethyl)ethoxy]methyl]guanine) against herpes simplex virus type 1 keratitis in rabbits.
    Current eye research, 1984, Volume: 3, Issue:8

    Topics: Acyclovir; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Conjunctivitis; Corneal Opacity; Drug Evaluation, Preclinical; Follow-Up Studies; Ganciclovir; Herpes Simplex; Idoxuridine; Iritis; Keratitis, Dendritic; Male; Neuritis; Ointments; Rabbits; Time Factors; Trigeminal Nerve

1984
Imaging the expression of transfected genes in vivo.
    Cancer research, 1995, Dec-15, Volume: 55, Issue:24

    Topics: Animals; Arabinofuranosyluracil; Autoradiography; Ganciclovir; Gene Expression; Genetic Therapy; Idoxuridine; Rats; RNA, Messenger; Thymidine Kinase; Transfection; Tumor Cells, Cultured

1995
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
    Antiviral research, 1996, Volume: 31, Issue:3

    Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Formazans; Ganciclovir; Humans; Idoxuridine; Organophosphonates; Organophosphorus Compounds; Purines; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1996
In vitro effects of antiviral agents on human keratocytes.
    Cornea, 2001, Volume: 20, Issue:1

    Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Colorimetry; Corneal Stroma; Cytosine; Dose-Response Relationship, Drug; Fibroblasts; Ganciclovir; Humans; Idoxuridine; Microscopy, Phase-Contrast; Organophosphonates; Organophosphorus Compounds; Trifluridine

2001
In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1.
    American journal of veterinary research, 2004, Volume: 65, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Foscarnet; Ganciclovir; Guanine; Idoxuridine; In Vitro Techniques; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Varicellovirus; Virus Replication

2004
Combined antiherpetic effect of complex preparation "Viferon-eye drops" and modified nucleosides.
    Bulletin of experimental biology and medicine, 2006, Volume: 141, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Dose-Response Relationship, Drug; Ganciclovir; Herpesvirus 1, Human; Idoxuridine; Inhibitory Concentration 50; Interferon alpha-2; Interferon-alpha; Nucleosides; Ophthalmic Solutions; Recombinant Proteins; Ribavirin; Species Specificity; Vero Cells; Vidarabine

2006
Application of bioluminescence imaging to therapeutic intervention of herpes simplex virus type I - Thymidine kinase/ganciclovir in glioma.
    Cancer letters, 2010, Nov-01, Volume: 297, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Female; Ganciclovir; Genes, Reporter; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Glioblastoma; Herpesvirus 1, Human; Idoxuridine; Kinetics; Lentivirus; Luciferases, Firefly; Luminescent Measurements; Mice; Mice, Inbred BALB C; Mice, Nude; Positron-Emission Tomography; Rats; Recombinant Fusion Proteins; Thymidine Kinase; Tumor Burden

2010