idoxuridine has been researched along with 5-(2-iodovinyl)-2'-deoxyuridine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (74.19) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balzarini, J; Bernaerts, R; De Clercq, E; Verbruggen, A | 1 |
| Cleator, GM; Klapper, PE; Lewis, AG; Longson, M; Templeton, P | 1 |
| Ayusawa, D; Balzarini, J; De Clercq, E; Seno, T; Shimizu, K; Verbruggen, A | 1 |
| De Clercq, E; Ichimura, H; Kit, S | 1 |
| Bruce, JM; Cleator, GM; Klapper, PE; Longson, M | 1 |
| Knaus, EE; Rogers, JA; Stathaki, S; Tovell, D; Tyrrell, DL; Wiebe, LI | 1 |
| Balzarini, J; Bernaerts, R; De Clercq, E; Herdewijn, P; Verbruggen, A | 1 |
| Ayusawa, D; Balzarini, J; de Clercq, E; Seno, T | 1 |
| Ayusawa, D; Balzarini, J; De Clercq, E; Seno, T; Verbruggen, A | 1 |
| Choi, EI; De Clercq, E; Lin, JC; Pagano, JS; Smith, MC; Verbruggen, A | 1 |
| De Clercq, E; Konno, K; Mori, S; Shigeta, S; Yokota, T | 1 |
| Ayusawa, D; Balzarini, J; De Clercq, E; Ren, L; Seno, T; Shimizu, K | 1 |
| De Clercq, E; De Roo, M; Julien, C; Verbruggen, A | 1 |
| De Clercq, E; Konno, K; Shigeta, S; Verbruggen, A; Yokota, T | 1 |
| Cleator, GM; Klapper, PE; Lewis, AG; Longson, M; Sharma, HL | 1 |
| Gill, MJ; Iwashina, T; Knaus, EE; Samuel, J; Tovell, DR; Tyrrell, DL; Wiebe, LI | 1 |
| Ameye, C; Bernaerts, R; Busson, R; De Clercq, E; de Roo, M; Maudgal, PC; Missotten, L; Verbruggen, AM | 1 |
| De Clercq, E; Descamps, J | 1 |
| Cheng, YC; De Clercq, E; Dutschman, G; Jones, AS; Rahim, SG; Verhelst, G; Walker, RT | 1 |
| Bergstrom, DE; de Clercq, E; Descamps, J; Verhelst, G | 1 |
| Allaudeen, HS; Chen, MS; De Clercq, E; Lee, JJ; Prusoff, WH | 1 |
| Knaus, EE; Samuel, J; Tyrrell, DL; Wiebe, LI | 1 |
| Gill, MJ; Knaus, EE; Samuel, J; Tyrrell, DL; Wiebe, LI | 1 |
| Balzarini, J; De Clercq, E; Knaus, EE; Morin, KW; Wiebe, LI | 1 |
| Atrazheva, ED; Knaus, EE; Morin, KW; Wiebe, LI | 1 |
| Ahn, SH; Awh, OD; Choi, CW; Choi, TH; Kwon, HC; Lim, SM | 1 |
| Chung, JK; Jeong, JM; Kang, JH; Kim, CW; Kim, KI; Lee, DS; Lee, MC; Lee, YJ; Shin, JH | 1 |
| Cheon, GJ; Choi, CW; Choi, TH; Chung, WS; Jang, SJ; Kang, JH; Kim, KI; Kwon, HC; Lee, KC; Lee, TS; Lee, YJ; Lim, SM; Ryu, CJ; Woo, KS | 1 |
| Balzarini, J; De Clercq, E; Herdewijn, P; Vanderhaeghe, H | 1 |
| Balzarini, J; De Clercq, E; Khalili, P; Knaus, EE; Naimi, E; Wiebe, LI; Zhou, A | 1 |
| Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE | 1 |
31 other study(ies) available for idoxuridine and 5-(2-iodovinyl)-2'-deoxyuridine
| Article | Year |
|---|---|
Role of the incorporation of (E)-5-(2-iodovinyl)-2'-deoxyuridine and its carbocyclic analogue into DNA of herpes simplex virus type 1-infected cells in the antiviral effects of these compounds.
Topics: Animals; Antiviral Agents; Centrifugation, Density Gradient; Cyclopentanes; Deoxyuridine; DNA, Viral; Idoxuridine; In Vitro Techniques; Simplexvirus; Vero Cells | 1990 |
Altered in vitro uptake of the radiolabelled antiviral imaging "probe" E-5-(2-125iodovinyl)-2'-deoxyuridine following administration of acyclovir.
Topics: Acyclovir; Animals; Antiviral Agents; Cell Line; Drug Interactions; Idoxuridine; Iodine Radioisotopes; Simplexvirus | 1989 |
Thymidylate synthase is the principal target enzyme for the cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine against murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 or type 2 thymidine kinase gene.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Division; Cell Line, Transformed; DNA; Genes, Viral; Idoxuridine; Mice; Simplexvirus; Thymidine Kinase; Thymidylate Synthase | 1987 |
Differential metabolism of (E)-5-(2-iodovinyl)-2'-deoxyuridine (IVDU) by equine herpesvirus type 1- and herpes simplex virus-infected cells.
Topics: Animals; Antiviral Agents; Cell Line; Cytosol; Herpesviridae; Herpesvirus 1, Equid; Idoxuridine; Kinetics; Phosphorylation; Simplexvirus; Thymidine Kinase; Vero Cells | 1987 |
Penetration of the blood-brain barrier by the antiviral drug (E)-5-(2-iodovinyl)-2'-deoxyuridine in a rat model of herpes encephalitis.
Topics: Animals; Antiviral Agents; Autoradiography; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry, Physical; Chromatography, Thin Layer; Encephalitis; Herpes Simplex; Idoxuridine; Iodine Radioisotopes; Radionuclide Imaging; Rats; Simplexvirus | 1988 |
Liposomes for targeted delivery of radioiodinated IVdU and 3-CH3-IVdU for non-invasive detection of herpes simplex virus encephalitis in mice.
Topics: Animals; Blood-Brain Barrier; Cholesterol; Drug Stability; Encephalitis; Herpes Simplex; Idoxuridine; Iodine Radioisotopes; Liposomes; Male; Mice; Mice, Inbred Strains; Phosphatidylcholines; Simplexvirus; Sulfoglycosphingolipids; Temperature | 1988 |
Selective antiherpetic activity of carbocyclic analogues of (E)-5-(2-halogenovinyl)-2'-deoxyuridines: dependence on specific phosphorylation by viral thymidine kinase.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Idoxuridine; Kidney; Kinetics; Phosphorylation; Rabbits; Simplexvirus; Thymidine Kinase | 1985 |
Murine mammary FM3A carcinoma cells transformed with the herpes simplex virus type 1 thymidine kinase gene are highly sensitive to the growth-inhibitory properties of (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
Topics: Animals; Antiviral Agents; Bromodeoxycytidine; Bromodeoxyuridine; Cell Division; Cell Line; Female; Genes, Viral; Idoxuridine; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Phosphorylation; Simplexvirus; Thymidine Kinase; Transformation, Genetic | 1985 |
Highly selective cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine derivatives for murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 thymidine kinase gene.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Division; Cell Transformation, Viral; DNA; Idoxuridine; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Simplexvirus; Thymidine Kinase; Thymidylate Synthase; Tritium | 1985 |
Effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine on replication of Epstein-Barr virus in human lymphoblastoid cell lines.
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cell Line; DNA; DNA, Viral; Dose-Response Relationship, Drug; Herpesvirus 4, Human; Humans; Idoxuridine; Kinetics; Lymphocytes; Molecular Weight; Peptide Biosynthesis; Peptides; Viral Proteins; Virus Replication | 1985 |
Characterization of a varicella-zoster virus variant with altered thymidine kinase activity.
Topics: Aminopterin; Antiviral Agents; Bromodeoxyuridine; Cells, Cultured; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Floxuridine; Herpesvirus 3, Human; Humans; Idoxuridine; Microbial Sensitivity Tests; Phosphorylation; Thymidine; Thymidine Kinase | 1986 |
Establishment of mutant murine mammary carcinoma FM3A cell strains transformed with the herpes simplex virus type 2 thymidine kinase gene.
Topics: Acyclovir; Animals; Cell Line; Cell Transformation, Viral; Cloning, Molecular; Genes, Viral; Idoxuridine; Mammary Neoplasms, Experimental; Mice; Mutation; Simplexvirus; Thymidine Kinase | 1986 |
Simple quantitative radioiodination of (E)-5-(2-iodovinyl)-2'-deoxyuridine (IVDU) by exchange labelling.
Topics: Antiviral Agents; Encephalitis; Herpes Simplex; Humans; Idoxuridine; Iodine Radioisotopes; Radiochemistry; Radionuclide Imaging | 1986 |
Incorporation of (E)-5-(2-iodovinyl)-2'-deoxyuridine into deoxyribonucleic acids of varicella-zoster virus (TK+ and TK- strains)-infected cells.
Topics: Autoradiography; Biological Transport; Bromodeoxyuridine; Cells, Cultured; DNA, Viral; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; Idoxuridine; Nucleic Acid Hybridization; Thymidine; Thymidine Kinase; Time Factors; Virus Replication | 1987 |
Specific neuro-radiological diagnosis of herpes encephalitis in an animal model.
Topics: Animals; Antiviral Agents; Autoradiography; Blood-Brain Barrier; Brain; Carotid Arteries; Encephalitis; Etoposide; Female; Herpes Simplex; Idoxuridine; Injections, Intra-Arterial; Iodine Radioisotopes; Isotope Labeling; Radionuclide Imaging; Rats; Vero Cells | 1988 |
Pharmacokinetics and metabolism of E-5-(2-[131I]iodovinyl)-2'-deoxyuridine in dogs.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Encephalitis; Herpes Simplex; Idoxuridine; Iodine Radioisotopes; Kinetics | 1986 |
Ocular penetration of (125I)IVDU, a radiolabeled analogue of bromovinyldeoxyuridine.
Topics: Animals; Anterior Chamber; Cornea; Idoxuridine; Iodine Radioisotopes; Keratitis, Dendritic; Rabbits | 1985 |
Specific phosphorylation of E-5-(2-iodovinyl)-2'-deoxyuridine by herpes simplex virus-infected cells.
Topics: Animals; Cells, Cultured; Idoxuridine; Kidney; Mutation; Phosphorylation; Rabbits; Simplexvirus; Thymidine Kinase | 1981 |
Differential affinities of 5-(2-halogenovinyl)-2'-deoxyuridines for deoxythymidine kinases of various origins.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cytosol; Deoxyuridine; Herpesvirus 3, Human; Humans; Idoxuridine; In Vitro Techniques; Mitochondria; Phosphorylation; Rabbits; Simplexvirus; Substrate Specificity; Thymidine Kinase | 1981 |
Differential inhibition of herpes simplex viruses, type 1 (HSV-1) an type 2 (HSV-2), by (E)-5-(2-X-vinyl)-2'-deoxyuridines.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Deoxyuridine; Fluorodeoxyuridylate; Idoxuridine; Rabbits; Simplexvirus; Structure-Activity Relationship | 1981 |
Incorporation of E-5-(2-halovinyl)-2'-deoxyuridines into deoxyribonucleic acids of herpes simplex virus type 1-infected cells.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Viral; Deoxyuridine; DNA Polymerase II; DNA Replication; DNA, Viral; Halogens; Idoxuridine; Kidney; Simplexvirus; Structure-Activity Relationship; Vinyl Compounds; Virus Replication | 1982 |
Synthesis of 131I, 125I and 82Br labelled (E)-5-(2-halovinyl)-2'-deoxyuridines.
Topics: Antiviral Agents; Bromine; Bromodeoxyuridine; Encephalitis; Herpes Simplex; Humans; Idoxuridine; Iodine Radioisotopes; Isotope Labeling; Radioisotopes; Radionuclide Imaging | 1984 |
Quantitative uptake studies of 131I-labeled (E)-5-(2-iodovinyl)-2'-deoxyuridine in herpes simplex virus-infected cells in vitro.
Topics: Animals; Colony-Forming Units Assay; Herpes Simplex; Idoxuridine; Iodine Radioisotopes; Isotope Labeling; Kidney; Rabbits; Thymidine Kinase; Time Factors; Virus Cultivation | 1984 |
Novel (E)-5-(2-iodovinyl)-2'-deoxyuridine derivatives as potential cytostatic agents against herpes simplex virus thymidine kinase gene transfected tumors.
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Drug Screening Assays, Antitumor; Genetic Therapy; Herpesvirus 1, Human; Herpesvirus 2, Human; Hydrolysis; Idoxuridine; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Substrate Specificity; Thymidine Kinase; Thymidine Phosphorylase; Transfection; Tumor Cells, Cultured | 1995 |
Synthesis and cellular uptake of 2'-substituted analogues of (E)-5-(2-[125I]iodovinyl)-2'-deoxyuridine in tumor cells transduced with the herpes simplex type-1 thymidine kinase gene. Evaluation as probes for monitoring gene therapy.
Topics: Animals; Antiviral Agents; Biological Transport; Cell Line; Genes, Viral; Genetic Therapy; Genetic Vectors; Herpesvirus 1, Human; Idoxuridine; Indicators and Reagents; Iodine Radioisotopes; Isotope Labeling; Kinetics; Mice; Molecular Structure; Moloney murine leukemia virus; Monitoring, Physiologic; Recombinant Proteins; Structure-Activity Relationship; Thymidine Kinase; Transfection | 1997 |
In vivo comparison of IVDU and IVFRU in HSV1-TK gene expressing tumor bearing rats.
Topics: Animals; Cell Line, Tumor; Drug Monitoring; Drug Stability; Floxuridine; Genetic Therapy; Herpesvirus 1, Human; Idoxuridine; Iodine Radioisotopes; Neoplasms; Radiopharmaceuticals; Rats; Substrate Specificity; Thymidine Kinase; Tissue Distribution | 2004 |
Feasibility of sodium/iodide symporter gene as a new imaging reporter gene: comparison with HSV1-tk.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Colonic Neoplasms; Feasibility Studies; Gene Expression Profiling; Genes, Reporter; Herpesvirus 1, Human; Humans; Idoxuridine; Mice; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Symporters; Thymidine Kinase; Tissue Distribution; Transfection | 2004 |
Application of bioluminescence imaging to therapeutic intervention of herpes simplex virus type I - Thymidine kinase/ganciclovir in glioma.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Female; Ganciclovir; Genes, Reporter; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Glioblastoma; Herpesvirus 1, Human; Idoxuridine; Kinetics; Lentivirus; Luciferases, Firefly; Luminescent Measurements; Mice; Mice, Inbred BALB C; Mice, Nude; Positron-Emission Tomography; Rats; Recombinant Fusion Proteins; Thymidine Kinase; Tumor Burden | 2010 |
Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2'-deoxyuridines and (E)-5-(2-halovinyl)-2'-deoxycytidines.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Bromodeoxyuridine; Cell Division; Cell Line; Cyclopentanes; Cytopathogenic Effect, Viral; Deoxycytidine; Deoxyuridine; Herpes Simplex; Humans; Mice; Mice, Hairless; Rabbits; Rats; Simplexvirus; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Cultivation | 1985 |
Synthesis of 3'- and 5'-nitrooxy pyrimidine nucleoside nitrate esters: "nitric oxide donor" agents for evaluation as anticancer and antiviral agents.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Chlorocebus aethiops; Deoxycytidine; Deoxyuridine; Drug Screening Assays, Antitumor; Humans; Hydrolysis; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Pyrimidine Nucleosides; Rats; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set.
Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship | 2007 |