idazoxan hydrochloride has been researched along with pyrimethamine in 1 studies
| Studies (idazoxan hydrochloride) | Trials (idazoxan hydrochloride) | Recent Studies (post-2010) (idazoxan hydrochloride) | Studies (pyrimethamine) | Trials (pyrimethamine) | Recent Studies (post-2010) (pyrimethamine) |
|---|---|---|---|---|---|
| 14 | 0 | 3 | 5,088 | 738 | 1,047 |
| Protein | Taxonomy | idazoxan hydrochloride (IC50) | pyrimethamine (IC50) |
|---|---|---|---|
| Dihydrofolate reductase | Homo sapiens (human) | 3.1057 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.1007 | |
| Beta-hexosaminidase subunit alpha | Homo sapiens (human) | 6.8333 | |
| Beta-hexosaminidase subunit beta | Homo sapiens (human) | 6.4 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 4.3 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.0609 | |
| Dihydrofolate reductase | Pneumocystis carinii | 3.25 | |
| Dihydrofolate reductase | Candida albicans | 5 | |
| Low molecular weight phosphotyrosine protein phosphatase | Homo sapiens (human) | 15.615 | |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | 0.39 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.3217 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum 3D7 | 2.48 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 2.0727 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
1 other study(ies) available for idazoxan hydrochloride and pyrimethamine
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |