idazoxan has been researched along with yohimbine in 317 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (29.65) | 18.7374 |
| 1990's | 165 (52.05) | 18.2507 |
| 2000's | 43 (13.56) | 29.6817 |
| 2010's | 15 (4.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, J; Brown, CM; Clague, RU; Clark, RD; Kilpatrick, AT; MacKinnon, AC; Nelson, JT; Repke, DB; Spedding, M | 1 |
| Berger, J; Brown, CM; Clark, RD; Garg, P; Kilpatrick, AT; MacKinnon, AC; Spedding, M; Weinhardt, KK | 1 |
| Brown, CM; Clague, RU; Clark, RD; Kilpatrick, AT; MacKinnon, AC; Repke, DB; Spedding, M | 1 |
| Lattimer, N; Rhodes, KF; Sharma, S; Ward, TJ; Waterfall, JF; White, JF | 1 |
| Harsing, LG; Somogyi, GT; Szabo, L; Szantay, C; Toth, I; Vizi, ES | 1 |
| Haubrich, DR; Hlasta, DJ; Luttinger, D; Perrone, MH; Silbernagel, MJ; Ward, SJ | 1 |
| Alexander, EJ; Bailey, DM; Castaldi, MJ; Ferrari, RA; Haubrich, DR; Luttinger, DA; Perrone, MH; Wentland, MP | 1 |
| Butler, RC; Chapleo, CB; Doxey, JC; Myers, PL; Roach, AG; Smith, CF | 1 |
| Anderson, PS; Guare, JP; Halczenko, W; Huff, JR; Hunt, CA; King, SW; Lotti, VJ; Randall, WC; Saari, WS; Taylor, DA | 1 |
| Bondinell, W; Hieble, JP; Ruffolo, RR | 1 |
| Blitzer, RD; Cornfeldt, M; Davis, L; Effland, RC; Haroutunian, V; Huger, FP; Klein, JT; Landau, E; Martin, LL; Olsen, GE; Petko, WW; Smith, CP; Wilker, JC; Wong, GS | 1 |
| Brunel, P; Calmel, F; Chaplain, C; Chopin, P; Imbert, T; Marien, M; Mayer, P; Pauwels, PJ; Piedecoq, C; Schambel, P; Vidaluc, JL; Wurch, T | 1 |
| Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mammoli, V; Mattioli, L; Perfumi, M; Piergentili, A; Pigini, M; Quaglia, W; Titomanlio, F | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Corbett, R; Dunn, RW | 1 |
| Paris, H; Remaury, A | 1 |
| Buchholz, J; Duckles, SP; Friedman, D; Tsai, H | 1 |
| Alburges, ME; Bylund, DB; Hunt, MA; Wamsley, JK | 1 |
| Bowes, MP; Hopper, DL; Kernan, WJ; Peters, RH | 1 |
| Coupry, I; Lachaud, V; Limon, I; Parini, A; Tesson, F | 1 |
| Schwietert, R; Van Zwieten, PA; Wilffert, B; Wilhelm, D | 1 |
| Harsing, LG; Vizi, ES | 1 |
| Schreihofer, AM; Sved, AF; Tsukamoto, K | 1 |
| Charney, DS; Heninger, GR; Krystal, JH; McDougle, CJ; Price, LH; Woods, SW | 1 |
| Birkett, SD; Griffin, IJ; Jackson, HC; Nutt, DJ | 1 |
| Leslie, FM; Raymon, HK; Smith, TD | 1 |
| Blier, P; Chodkiewicz, JP; Galzin, AM; Langer, SZ; Lista, A; Loô, H; Poirier, MF; Ramdine, R; Redondo, A; Roux, FX | 1 |
| Leidenheimer, NJ; Schechter, MD | 1 |
| Branch, CA; Knuepfer, MM | 1 |
| Blaxall, HS; Bylund, DB; Lawhead, RG | 1 |
| Litthauer, D; Oelofsen, W; van de Venter, M | 1 |
| Besson, JM; Guilbaud, G; Kayser, V | 2 |
| Carratù, MR; De Serio, A; Mitolo-Chieppa, D; Navarra, P; Preziosi, P; Serio, M | 1 |
| Clarke, RW; Harris, J | 2 |
| Proudfit, HK; Yeomans, DC | 1 |
| Limon, I; Parini, A; Tesson, F | 1 |
| Ger, LP; Tseng, CJ; Tung, CS | 1 |
| Uhlén, S; Wikberg, JE | 1 |
| Convents, A; De Backer, JP; De Keyser, J; De Vos, H; Ebinger, G; Van Megen, IJ; Vauquelin, G | 1 |
| Noga, BR; Skoog, B | 1 |
| Bousquet, P; Feldman, J; Gonon, F; Mermet, C; Tibiriça, E | 1 |
| Gitler, MS; Jose, PA; Piccio, MM; Robillard, JE | 1 |
| Guyenet, PG; Nosjean, A | 1 |
| Bianchi, G | 1 |
| Hirohashi, M; Takasuna, K; Tamura, K; Yamashita, N | 1 |
| Elliott, JM; Glue, P; Kay, G; Nutt, DJ; Payvandi, N | 1 |
| Dausse, JP; Lacolle, JY; Yablonsky, F | 1 |
| Czerwiec, E; De Backer, JP; De Potter, W; De Vos, H; Vauquelin, G | 1 |
| Bültmann, R; Starke, K; von Kügelgen, I | 2 |
| Berlan, M; Galitzky, J; Montastruc, P; Tran, MA | 1 |
| Koskinen, LO; Seligsohn, EE | 1 |
| Horváth, E; Jaszlits, L; Rabloczky, G | 1 |
| Arnsten, AF; Leslie, FM | 1 |
| Connelly, CD; Hollingworth, RM; Orr, N; Raffa, RB | 1 |
| Bousquet, P; Feldman, J; Gonon, F; Mermet, C; Monassier, L; Tibiriça, E | 1 |
| Heistracher, M; Philippu, A; Prast, H | 1 |
| Hamahashi, T; Itoh, T; Kamisaki, Y; Okada, CM | 1 |
| Gulati, A | 1 |
| Grealy, M; O'Donnell, JM | 1 |
| Hamilton, CA; Jardine, E; Reid, JL; Yakubu, MA | 1 |
| Berlan, M; Galitzky, J; Lafontan, M; Larrouy, D | 1 |
| Deighton, NM; Hamilton, CA; Reid, JL; Yakubu, MA | 1 |
| Danzebrink, RM; Gebhart, GF | 1 |
| Lafontan, M; Langin, D; Paris, H | 1 |
| Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M | 1 |
| Carpéné, C; Galitzky, J; Lafontan, M; Langin, D; Larrouy, D | 1 |
| Berlan, M; Galitzky, J; Lafontan, M; Montastruc, JL; Senard, JM; Stillings, M | 1 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill, M; Feldman, J | 1 |
| Hsu, WH; Ko, JC; Smith, BE | 1 |
| Bernardini, MC; Blandizzi, C; del Tacca, M; Natale, G | 1 |
| Atlas, D; Coupry, I; Parini, A; Podevin, RA; Uzielli, I | 1 |
| Breuiller, M; Ferré, F; Leroy, MJ; Litime, MH; Rouot, B | 1 |
| Brandon, S; Cragoe, EJ; Guyer, CA; Horstman, DA; Limbird, LE; Wilson, AL | 1 |
| Berlan, M; Estan, L; Montastruc, JL; Senard, JM; Tran, MA | 1 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill, M; Feldman, J; Tibiriça, E | 1 |
| Scheinin, H; Virtanen, R | 1 |
| Claeys, M; De Potter, WP; Dillen, L | 1 |
| Bache, RJ; Chen, DG; Dai, XZ | 1 |
| Chariot, J; Chovet, M; Rozé, C; Sautereau, D; Tsocas, A | 1 |
| Limberger, N; Mayer, A; Singer, EA; Starke, K; Valenta, B; Zier, G | 1 |
| Convents, A; Convents, D; De Backer, JP; De Keyser, J; Vauquelin, G | 1 |
| Couture, R; Laneuville, O; Reader, TA | 1 |
| Hey, JA; Ito, T; Koss, MC | 2 |
| Behrendt, J; Brodde, OE; Insel, PA; Michel, MC; Motulsky, HJ; Schnepel, B; Tschada, R | 1 |
| Jurcovicová, J; Krulich, L; Le, T | 1 |
| Lafontan, M; Langin, D | 1 |
| Dausse, JP; Yablonsky, F | 1 |
| Coupry, I; Koenig, E; Lachaud, V; Parini, A; Podevin, RA | 2 |
| Grenhoff, J; Svensson, TH | 1 |
| Lafontan, M; Langin, D; Paris, H; Stillings, MR | 1 |
| Cattaneo, AG; Doxey, JC; Efendic, S; Ostenson, CG | 1 |
| Farjam, A; Greven, J | 1 |
| Hanson, CE; Hembrough, FB; Hsu, WH; Schaffer, DD | 1 |
| Ely, DL; Folkow, B; Gustafsson, H; Nilsson, H; Sjöblom-Widfeldt, N | 1 |
| Colindres, RE; Strandhoy, JW; Wolff, DW | 1 |
| Heffner, TG; Meltzer, LT; Wiley, JN | 1 |
| Carpéné, C; Lafontan, M; Langin, D; Saulnier-Blache, JS | 1 |
| Feder, HH; Peterson, CS; Thornton, JE; Vincent, PA | 1 |
| Bidet, M; Coupry, I; Lachaud, V; Parini, A; Podevin, RA; Poujeol, P | 1 |
| Bowman, CL; Kimelberg, HK | 1 |
| Kenakin, TP; Novak, PJ | 1 |
| Bickford-Wimer, PC; Freedman, R; Parfitt, KD | 1 |
| Hamilton, CA; Howie, CA; Reid, JL; Yakubu, MA | 1 |
| Lattimer, N; Rhodes, KF; Waterfall, JF | 1 |
| Pettibone, DJ; Pfleuger, AB; Totaro, JA | 1 |
| Loiacono, RE; Rand, MJ; Story, DF | 1 |
| Ramage, AG; Tomlinson, A | 1 |
| Colpaert, FC; Janssen, PA | 2 |
| Folkow, B; Nilsson, H; Sjöblom, N | 1 |
| Howe, BB; Keith, RA; Salama, AI | 1 |
| Bond, RA; Charlton, KG; Clarke, DE | 1 |
| György, L; Ludvig, N; Vizi, ES | 1 |
| Carlsson, M; Eriksson, E; Nilsson, C; Söderpalm, B | 1 |
| Dickinson, KE; McKernan, RM; Miles, CM; Sever, PS | 1 |
| Hicks, PE; Langer, SZ; Najar, M; Vidal, M | 1 |
| Davidson, JM; Kwong, LL; Peroutka, SJ; Smith, ER | 1 |
| Bousquet, P; Feldman, J | 1 |
| Simson, PE; Weiss, JM | 1 |
| Boyajian, CL; Leslie, FM | 1 |
| Gellman, RL; Kallianos, JA; McNamara, JO | 1 |
| Feder, HH; Thornton, J; Vincent, PA | 1 |
| Coupry, I; Dausse, JP; Parini, A; Podevin, RA | 1 |
| Davidson, JM; Lee, RL; Schnur, SL; Smith, ER | 2 |
| Claeys, M; De Potter, WP; Dillen, L; Duchateau, A | 1 |
| Blaustein, JD; Turcotte, J | 1 |
| Cannon de Rodriguez, W; Shaikh, IM; Skala, JP | 1 |
| Sanger, DJ | 2 |
| Tsurusaki, M | 1 |
| Berlan, M; Galitzky, J; Garrigues, M; Lafontan, M; Rivière, D; Taouis, M | 1 |
| Dausse, JP; Lacolle, JY; Riffaud, JP; Yablonsky, F | 1 |
| Galzin, AM; Langer, SZ; Taranger, MA | 1 |
| Galzin, AM; Langer, SZ | 1 |
| Appleby, GJ; Clark, MG; Colquhoun, EQ; Edwards, SJ; McKinstry, WJ; Rattigan, S; Richter, EA | 1 |
| Barr, SM; Hamilton, CA; Reid, JL | 1 |
| Boyajian, CL; Leslie, FM; Loughlin, SE | 1 |
| Convents, A; De Backer, JP; Vauquelin, G | 1 |
| de Champlain, J; Foucart, S; Nadeau, R | 1 |
| Hamilton, CA; Reid, JL; Yakubu, MA | 1 |
| Dabiré, H; Dausse, JP; Meyer, P; Mouillé, P; Schmitt, H | 1 |
| Doxey, JC; Roach, AG; Smith, CF | 1 |
| Goldstein, JM; Knobloch, LC; Malick, JB | 1 |
| Qian, JQ; Ruffolo, RR; Timmermans, PB; van Zwieten, PA | 1 |
| Doxey, JC; Lane, AC; Roach, AG; Virdee, NK | 1 |
| Langer, SZ; Medgett, IC | 1 |
| Bradshaw, CM; Sheridan, RD; Szabadi, E | 1 |
| García-Sáinz, JA; Pushpendran, CK | 1 |
| North, RA; Yoshimura, M | 1 |
| Antolik, EK; Robinson, EL; Yarbrough, GG | 1 |
| Elliott, HL; Jones, CR; Lawrie, CB; Reid, JL; Vincent, J | 1 |
| Gadie, B; Lane, AC; McCarthy, PS; Tulloch, IF; Walter, DS | 1 |
| Doxey, JC; Roach, AG; Strachan, DA; Virdee, NK | 1 |
| Curtis-Prior, PB; Tan, S | 1 |
| Dedek, J; Scatton, B; Zivkovic, B | 1 |
| Galzin, AM; Langer, SZ; Moret, C | 1 |
| Carter, R; Shuster, S | 1 |
| Scatton, B | 1 |
| Chang, SS; Cheng, JT | 1 |
| Thomas, GP | 2 |
| Burroughs, GJ; Cole, JC; Laverty, CR; Rodgers, RJ; Sheriff, NC; Sparham, EA | 1 |
| Hussain, JF; Kendall, DA; Pinthong, D; Wilson, VG | 1 |
| Berlie, JR; Blaxall, HS; Bylund, DB; Chacko, DM; Cooley, ME; Iversen, LJ | 1 |
| Evans, RG; Haynes, JM | 2 |
| Szabo, B; Urban, R | 1 |
| Cooke, HJ; Wood, JD; Zafirov, DH | 1 |
| Beleslin, DB; Jovanović-Mićić, D; Samardzić, R | 1 |
| Blaylock, NA; Kendall, DA; Wilson, VG; Wright, IK | 1 |
| Halme, M; Savola, JM; Scheinin, M; Sjöholm, B | 1 |
| Kirk, HR; Monroe, PJ; Smith, DJ; Smith, DL | 1 |
| Erdbrügger, W; Michel, MC; Otto, T; Raulf, M | 1 |
| Ferrari, F; Giuliani, D; Pelloni, F | 1 |
| Barna, I; Haller, J; Kovács, JL | 1 |
| Rossi, R; Scharrer, E | 1 |
| Haapalinna, A; Riekkinen, P; Sirviö, J; Yavich, L | 1 |
| Allen, AM; Guyenet, PG | 1 |
| Li, P; Smyth, DD | 1 |
| Robinson, NE; Wang, Z; Yu, M | 1 |
| Dunn, RW; La Marca, S | 1 |
| Starke, K; Szabo, B; Urban, R | 1 |
| Blaxall, HS; Bylund, DB; Iversen, LJ; O'Rourke, MF | 1 |
| Corcoran, ME; Pelletier, MR | 1 |
| Pennefather, JN; Ventura, S | 1 |
| Ala-Uotila, S; Kurose, H; Marjamäki, A; Oker-Blom, C; Pohjanoksa, K; Scheinin, M; Sizmann, D | 1 |
| Hertz, L; Huang, R | 1 |
| Costentin, J; Dupuis, R; Simon, P | 1 |
| Elased, KM; Furman, BL | 1 |
| Boer, GJ; Feenstra, MG; van Veldhuizen, MJ | 1 |
| Bylund, DB; Iversen, LJ; Lomasney, JW; O'Rourke, MF | 1 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill, M; Greney, H; Stutzmann, J | 1 |
| Dzwonczyk, S; Grover, GJ; Sargent, CA | 1 |
| Kulkarni, SK; Sharma, A | 1 |
| Chapouthier, G; Jacquot, F; Sara, S; Save, E; Venault, P | 1 |
| Berlan, M; Galitzky, J; Le Corre, P; Le Verge, R | 1 |
| Legrand, C; Maltier, JP; Mhaouty, S; Rigolot, C | 1 |
| Agnati, LF; Frasoldati, A; Grimaldi, R; Marrama, P; Pich, EM; Zini, I | 1 |
| Etgen, AM; Karkanias, GB | 1 |
| Hussain, JF; Kendall, DA; Wilson, VG | 1 |
| Buchholz, J; Duckles, SP; Tsai, H | 1 |
| De Backer, JP; De Keyser, J; De Vos, H; Van Liefde, I; Vauquelin, G | 1 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill-Kieffer, M; Greney, H; Zhang, J | 1 |
| Oriowo, MA | 1 |
| Ivankovich, AD; Kroin, JS; Lubenow, TR; McCarthy, RJ; Penn, RD | 1 |
| Redfern, WS; Williams, A | 1 |
| Bousquet, P; De Jong, W; Feldman, J; Monassier, L; Roegel, JC | 1 |
| Hayashi, Y; Kamibayashi, T; Mammoto, T; Takada, K; Yamatodani, A; Yoshiya, I | 1 |
| Camacho, F; Smith, CP; Vargas, HM; Winslow, JT | 1 |
| Gaynor, PJ; Lookingland, KJ; Simmons, CR; Tucker, HA | 1 |
| Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G | 1 |
| Broqua, P; Dahl, SG; Gauthier-Martin, B; Junien, JL; Riviere, PJ; Rocher, MN; Wettstein, JG | 1 |
| Savola, JM; Savola, MK | 1 |
| Bylund, DB; Cerutis, DR; Deupree, JD; Hinton, KA | 1 |
| Banyasz, T; Kovacs, T; O'Donnell, JM | 1 |
| Chayvialle, JA; Chéry-Croze, S; Détolle-Sarbach, S; Guez, D; Miampamba, M | 1 |
| Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM | 1 |
| Haller, J; Kovács, JL; Makara, GB | 1 |
| Abadir, AR; Gintautas, J; Kraynack, BJ; Kwalburn, M; Mayda, J | 1 |
| Abdel-Rahman, AA; Mao, L | 1 |
| Esteban, S; García-Sevilla, JA; Lladó, J | 1 |
| Avellar, MC; Markus, RP | 1 |
| Bousquet, P; Dontenwill, M; Ehrhardt, JD; Greney, H; Molines, A; Senecheau, P | 1 |
| Hudson, AL; Wikberg, JE | 1 |
| Kadota, S; Kohno, S; Matsumoto, K; Tezuka, Y; Watanabe, H | 1 |
| Greven, J; Hohage, H; Schlatter, E | 1 |
| Ankorina-Stark, I; Haxelmans, S; Hohage, H; Schlatter, E | 1 |
| El-Kadi, AO; Sharif, SI | 1 |
| Elliott, J | 1 |
| Goldstein, I; Huang, YH; Moreland, RB; Traish, AM | 1 |
| Göthert, M; Jakschik, J; Likungu, J; Molderings, GJ | 1 |
| Diaz, A; Dickenson, AH; Mayet, S | 1 |
| Akerman, KE; Cockcroft, V; Huifang, G; Jansson, CC; Kukkonen, JP; Savola, JM; Wurster, S | 1 |
| Greven, J; Hess, K; Hohage, H; Jahl, C; Schlatter, E | 1 |
| Dambrova, M; Gu, Y; Näsman, J; Schiöth, HB; Uhlén, S; Wikberg, JE; Wikberg-Matsson, A | 1 |
| Birdsall, NJ; Lazareno, S; Leppik, RA; Mynett, A | 1 |
| Bach, KB; Mitchell, GS | 1 |
| Dickenson, AH; Green, GM; Lyons, L | 1 |
| Cleale, RM; Hadcock, JR; Ingling, JM; Pausch, MH; Search, DJ | 1 |
| Audinot, V; Chaput, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Nicolas, JP; Richard, N; Touzard, M; Verrièle, L | 1 |
| Caramona, MM; Figueiredo, IV; Guimarães, S; Moura, D; Paiva, MQ | 1 |
| Kimura, K; Kise, M; Masui, Y; Niida, H; Shirouchi, Y; Tajima, K; Ueda, F; Yamamoto, O | 1 |
| Chariot, J; Nagain-Domaine, C; Presset, O; Rozé, C | 1 |
| Chung, JM; Coggeshall, RE; Han, HC; Lee, DH; Moon, DE; Xie, J | 1 |
| Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P | 1 |
| Kang, KW; Kang, SY; Kim, ND; Vanhoutte, PM | 1 |
| Bousquet, P; Dontenwill, M; Greney, H; Heemskerk, F; Magnier, C; Vonthron, C | 1 |
| Bousquet, P; Devedjian, J; Dontenwill, M; Greney, H; Ordener, C; Parini, A | 1 |
| Debowski, T; Krzystanek, E; Krzystanek, M; Saczewski, F; Trzeciak, H | 1 |
| Bousquet, P; Bruban, V; Dontenwill, M; Ehrhardt, JD; Feldman, J; Greney, H; Schann, S | 1 |
| Ricci, D; Taira, CA | 1 |
| Brotchie, JM; Crossman, AR; Fox, SH; Henry, B; Peggs, D | 1 |
| Cox, SL; Gaiser, EG; Meyer, A; Starke, K; Trendelenburg, AU | 1 |
| Holmberg, M; Kurose, H; Miettinen, R; Scheinin, M | 1 |
| Hillilä, M; Lähdesmäki, J; Pyykkö, K; Scheinin, M; Sjöholm, B | 1 |
| McAllister, KH; Rey, B | 1 |
| Cockcroft, V; Frang, H; Marjamäki, A; Pihlavisto, M; Scheinin, M | 1 |
| Gacar, MN; Ulak, G; Utkan, T; Yardimoglu, M; Yildiran, HG | 1 |
| Benamour, K; Chang-Fong, J; Cussac, M; Morand, JM; Szymonski, B; Thomasson, F | 1 |
| Bylund, DB; Gerety, ME; Happe, HK; Murrin, LC | 1 |
| Eisenach, JC; Li, X; Pan, HL; Paqueron, X; Zhao, Z | 1 |
| Castrucci, AM; de Oliveira, AR; Scarparo, AC; Visconti, MA | 1 |
| Baldwin, J; Chang, CH; Ernsberger, P; Gold, G; Ivanov, TR; Jones, JC; Pickard, RT; Piletz, JE; Reis, DJ; Roth, B; Sharp, JD; Zhu, H | 1 |
| Chen, Y; Code, WE; Hertz, L; Zhao, Z | 1 |
| Aoki, K; Johnson, JM; Kosiba, WA; Stephens, DP | 1 |
| Akerman, KE; Jansson, CC; Kukkonen, JP | 1 |
| Birkle, DL; White, DA | 1 |
| McAllister, KH | 1 |
| Hayward, LF | 1 |
| Bishai, JM; Buchholz, JN; Gheorghe, CP; Longo, LD; Meulenaar, R; Nijland, R; Penninga, L; Zhang, L; Zhao, Y | 1 |
| De Luca, LA; Menani, JV; Moreira, Tdos S; Renzi, A; Takakura, AC | 1 |
| Su, DF; Tang, CS; Wang, JW; Wang, WZ; Yang, J; Yuan, WJ | 1 |
| De Luca, LA; dos Santos Moreira, T; Menani, JV; Renzi, A; Takakura, AC | 1 |
| Artigues-Varin, C; Mulder, P; Richard, V; Thuillez, C; Varin, R | 1 |
| Fagerholm, V; Holmberg, M; Scheinin, M | 1 |
| Hou, SW; Qi, JS; Qiao, JT; Zhang, Y | 1 |
| Garcez-do-Carmo, L; Jurkiewicz, A; Piçarro, I; Santos, WC; Smaili, SS | 1 |
| Pan, YX; Ren, AJ; Su, DF; Tang, CS; Wang, WZ; Yuan, WJ | 1 |
| Raasmaja, A; Römer, L; Savola, JM; Wurster, S | 1 |
| Aricioglu, F; Dulger, G; Ercil, E | 1 |
| Aricioglu, F; Utkan, T | 1 |
| Andrade, CA; De Luca, LA; Martinez, G; Menani, JV; Oliveira, LB; Silva, DC | 1 |
| de Arruda Camargo, LA; Guarda, IF; Guarda, RS; Saad, WA; Simões, S | 1 |
| Fagerholm, V; Hein, L; Philipp, M; Scheinin, M | 1 |
| Cardin, JA; Schmidt, MF | 1 |
| Amano, T; Ebiko, M; Kimura, Y; Sakurada, S; Yonezawa, A; Yoshizumii, M | 1 |
| Honda, M; Ono, H; Takasu, K; Tanabe, M | 1 |
| Cardinaletti, C; Carrieri, A; Gentili, F; Ghelfi, F; Mattioli, L; Perfumi, M; Pigini, M; Vesprini, C | 1 |
| Feliu-Mojer, M; Jiménez-Rivera, CA; Vázquez-Torres, R | 1 |
| Rawls, SM; Tallarida, RJ; Zisk, J | 1 |
| Amin, M; Rawls, SM; Zisk, J | 1 |
| Ferguson, TB; Johnson, FK; Johnson, RA; Joshi, MS; Lancaster, JR; Parthasarathy, S | 1 |
| Hashimoto, M; Ono, H; Tanabe, M | 1 |
| Chen, HX; Jiang, XZ; Li, J; Li, YF; Wang, NP; Zhang, YZ | 1 |
| Cahill, CM; Jhamandas, K; Milne, B; Sutak, M | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A; Matwyshyn, G; Zhang, Z | 1 |
| de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR | 1 |
| Aggarwal, S; Kim, E; Rawls, SM; Shavalian, B | 1 |
| Arszol, C; Bartenstein, P; Böning, G; Cumming, P; Josef Gildehaus, F; Mille, E; Rominger, A; Wängler, B | 1 |
| Chopde, CT; Gahane, AY; Kotagale, NR; Taksande, BG; Ugale, RR | 1 |
| Chancellor, MB; de Groat, WC; Kitta, T; Miyazato, M; Nonomura, K; Yoshimura, N | 1 |
| Bhalla, S; Gulati, A; Rapolaviciute, V | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A | 2 |
| Almeida, RL; Constancio, J; David, RB; De Luca, LA; Fracasso, JF; Menani, JV | 1 |
| Li, JX; Winter, JC; Zhang, Y | 1 |
| Andurkar, SV; Gulati, A | 1 |
| Docherty, JR | 1 |
| Holschbach, MA; Lonstein, JS; Olsewicz, J; Smith, CD | 1 |
| Alves, TB; Antunes, VR; Colombari, E; Ferreira-Neto, HC; Menani, JV; Moreira, TS; Takakura, AC; Totola, LT | 1 |
| Caselli, G; Ferrari, F; Lanza, M; Menghetti, I; Tremolada, D | 1 |
2 review(s) available for idazoxan and yohimbine
| Article | Year |
|---|---|
Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Humans; Molecular Conformation; Molecular Structure; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1995 |
Participation of imidazoline receptors and alpha(2-)-adrenoceptors in the central hypotensive effects of imidazoline-like drugs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Humans; Hypotension; Idazoxan; Imidazoles; Imidazoline Receptors; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 1999 |
2 trial(s) available for idazoxan and yohimbine
| Article | Year |
|---|---|
Dose-response relationship for oral idazoxan effects in healthy human subjects: comparison with oral yohimbine.
Topics: Adrenergic alpha-Antagonists; Adult; Affect; Behavior; Blood Pressure; Dioxanes; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Idazoxan; Male; Methoxyhydroxyphenylglycol; Neurosecretory Systems; Panic Disorder; Pulse; Yohimbine | 1992 |
Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adult; Benzazepines; Dioxanes; Epinephrine; Exercise; Humans; Idazoxan; Lipid Mobilization; Lipolysis; Male; Yohimbine | 1988 |
313 other study(ies) available for idazoxan and yohimbine
| Article | Year |
|---|---|
Structure-affinity relationships of 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1 ,6] naphthyridines at alpha-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Male; Muscle, Smooth; Naphthyridines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship | 1991 |
Affinity of 2-(tetrahydroisoquinolin-2-ylmethyl)- and 2-(isoindolin-2-ylmethyl)imidazolines for alpha-adrenoceptors. Differential affinity of imidazolines for the [3H]idazoxan-labeled alpha 2-adrenoceptor vs the [3H]yohimbine-labeled site.
Topics: Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Indoles; Isoquinolines; Ligands; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Yohimbine | 1990 |
(8a alpha,12a alpha,13a alpha)-5,8,8a,9,10,11,12,12a,13,13a-decahydro- 3-methoxy-12-(methylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridi ne, a potent and highly selective alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Guinea Pigs; Isoquinolines; Naphthyridines; Rabbits; Rats; Stereoisomerism; Structure-Activity Relationship; Vasoconstriction | 1989 |
Synthesis and structure-activity relationships of 2-sulfonamido-1,3,4,6,7,11b alpha-hexahydro-2H-benzo[a]quinolizines as alpha 2-adrenoceptor antagonists.
Topics: Animals; Chemical Phenomena; Chemistry; Clonidine; Dioxanes; Idazoxan; Male; Methoxamine; Molecular Conformation; Muscle Contraction; Muscles; Quinolizines; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Vas Deferens; Yohimbine | 1988 |
Berbanes: a new class of selective alpha 2-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Alkaloids; Animals; Berberine Alkaloids; Chemical Phenomena; Chemistry; Dioxanes; Guinea Pigs; Idazoxan; Ileum; Male; Muscle Contraction; Phentolamine; Prazosin; Pulmonary Artery; Rabbits; Rats; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1987 |
Alpha 2-adrenergic agonists/antagonists: the synthesis and structure-activity relationships of a series of indolin-2-yl and tetrahydroquinolin-2-yl imidazolines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Imidazoles; Indoles; Male; Mice; Nociceptors; Pain; Prazosin; Quinolines; Rats; Structure-Activity Relationship; Vas Deferens | 1987 |
Synthesis and antidepressant properties of novel 2-substituted 4,5-dihydro-1H-imidazole derivatives.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Chemical Phenomena; Chemistry; Dioxanes; Dopamine; Idazoxan; Imidazoles; Male; Mice; Muscle Contraction; Muscle, Smooth; Norepinephrine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Structure-Activity Relationship; Tetrabenazine | 1987 |
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Male; Mice; Phenylephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synapses; Vas Deferens | 1983 |
Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Male; Muscle Contraction; Piperazines; Pupil; Pyridines; Rats; Vas Deferens; Yohimbine | 1983 |
Synthesis and structure-activity relationships of N-propyl-N-(4-pyridinyl)-1H-indol-1-amine (besipirdine) and related analogs as potential therapeutic agents for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Biogenic Amines; Brain; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Parasympatholytics; Pyridines; Rats; Structure-Activity Relationship | 1996 |
New substituted 1-(2,3-dihydrobenzo[1, 4]dioxin-2-ylmethyl)piperidin-4-yl derivatives with alpha(2)-adrenoceptor antagonist activity.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Corpus Striatum; Dioxanes; Guanabenz; Hypothermia; Imidazoles; In Vitro Techniques; Male; Membranes; Mice; Neuroglia; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Structure-Activity Relationship | 2000 |
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Humans; Idazoxan; Imidazolines; Male; Mice; Morphine; Pain Measurement; Receptors, Adrenergic, alpha-2; Stereoisomerism | 2012 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Yohimbine-induced seizures involve NMDA and GABAergic transmission.
Topics: Animals; Bicuculline; Carbolines; Convulsants; Dioxanes; gamma-Aminobutyric Acid; Idazoxan; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Adrenergic, alpha; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Synaptic Transmission; Yohimbine | 1992 |
The insulin-secreting cell line, RINm5F, expresses an alpha-2D adrenoceptor and nonadrenergic idazoxan-binding sites.
Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brimonidine Tartrate; Cell Line; Cyclic AMP; Dioxanes; GTP-Binding Proteins; Idazoxan; Immunoblotting; Insulin; Insulin Secretion; Kinetics; Membranes; Pertussis Toxin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Tritium; Virulence Factors, Bordetella; Yohimbine | 1992 |
Influence of age on control of norepinephrine release from the rat tail artery.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Idazoxan; Male; Norepinephrine; Quinoxalines; Rats; Rats, Inbred F344; Receptors, Dopamine; Tail; Yohimbine | 1992 |
Differential localization of alpha 2-adrenergic receptor subtypes in brain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoradiography; Brain Chemistry; Clonidine; Dioxanes; Guanylyl Imidodiphosphate; Idazoxan; Male; Perfusion; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1992 |
Effects of yohimbine and idazoxan on motor behaviors in male rats.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Female; Idazoxan; Male; Motor Activity; Rats; Rats, Inbred Strains; Yohimbine | 1992 |
Characterization of imidazoline-guanidinium receptive sites in renal medulla from human kidney.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Guanidine; Guanidines; Humans; Idazoxan; Imidazoline Receptors; Indazoles; Kidney Medulla; Oxazoles; Rabbits; Receptors, Adrenergic; Receptors, Cell Surface; Receptors, Drug; Tritium; Yohimbine | 1992 |
The effect of some alpha-adrenoceptor antagonists on spontaneous myogenic activity in the rat portal vein and the putative involvement of ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; In Vitro Techniques; Male; Phentolamine; Portal Vein; Potassium Channels; Prazosin; Rats; Rats, Inbred Strains; Vasoconstriction; Yohimbine | 1992 |
Different sites of action for alpha 2-adrenoceptor antagonists in the modulation of noradrenaline release and contraction response in the vas deferens of the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Chromatography, High Pressure Liquid; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Vas Deferens; Xylazine; Yohimbine | 1992 |
Stimulation of alpha 2-adrenergic receptors in nucleus tractus solitarius is required for the baroreceptor reflex.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxanes; Dose-Response Relationship, Drug; Heart Rate; Idazoxan; Male; Medulla Oblongata; Microinjections; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Reflex; Stereotaxic Techniques; Tyramine; Yohimbine | 1992 |
The effects of idazoxan and other alpha 2-adrenoceptor antagonists on urine output in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Male; Quinolizines; Rats; Rats, Brattleboro; Rats, Wistar; Urodynamics; Yohimbine | 1992 |
Further pharmacological characterization of [3H]idazoxan binding sites in rat brain: evidence for predominant labeling of alpha 2-adrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Buffers; Dioxanes; Epinephrine; Idazoxan; Male; Phentolamine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Drug; Tritium; Yohimbine | 1992 |
Characterization of the 5-hydroxytryptamine receptor modulating the release of 5-[3H]hydroxytryptamine in slices of the human neocortex.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Animals; Cerebral Cortex; Child; Dioxanes; Electric Stimulation; Female; Humans; Idazoxan; In Vitro Techniques; Indoles; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium; Yohimbine | 1992 |
Evidence for noradrenergic involvement in mediating the FG 7142 discriminative stimulus.
Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Carbolines; Clonidine; Dioxanes; Discrimination, Psychological; Electroshock; Generalization, Stimulus; Idazoxan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Stress, Psychological; Yohimbine | 1992 |
Adrenergic mechanisms underlying cardiac and vascular responses to cocaine in conscious rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cocaine; Dioxanes; Drug Interactions; Heart Rate; Idazoxan; Male; Metoprolol; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation; Yohimbine | 1992 |
Alpha-2A is the predominant alpha-2 adrenergic receptor subtype in human spinal cord.
Topics: Adrenergic alpha-Antagonists; Dioxanes; Humans; Idazoxan; In Vitro Techniques; Indicators and Reagents; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1992 |
The effect of high concentrations of alpha 2-adrenoceptor antagonists on the lipolytic responsiveness of isolated human adipocytes.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Dioxanes; Female; Humans; Idazoxan; Isoproterenol; Lipolysis; Norepinephrine; Propanolamines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1992 |
Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arthritis; Dioxanes; Drug Interactions; Idazoxan; Injections, Intravenous; Norepinephrine; Pain; Pain Measurement; Rats; Receptors, Opioid; Tramadol; Yohimbine | 1992 |
Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat.
Topics: Adrenergic beta-Antagonists; Analgesics; Analysis of Variance; Animals; Arthritis, Experimental; Clonidine; Dioxanes; Idazoxan; Injections, Intravenous; Male; Pain; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Vocalization, Animal; Yohimbine | 1992 |
The effects of (+/-)-idazoxan and its stereoisomers on mouse vas deferens motility in vitro. A comparison with yohimbine.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Male; Mice; Norepinephrine; Stereoisomerism; Vas Deferens; Yohimbine | 1992 |
An analysis of adrenergic influences on the sural-gastrocnemius reflex of the decerebrated rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Decerebrate State; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Female; Idazoxan; Injections, Spinal; Male; Muscles; Prazosin; Rabbits; Reflex; Sural Nerve; Sympathetic Nervous System; Yohimbine | 1992 |
Antinociception induced by microinjection of substance P into the A7 catecholamine cell group in the rat.
Topics: Afferent Pathways; Analgesics; Animals; Blood Pressure; Catecholamines; Dioxanes; Female; Hot Temperature; Idazoxan; Injections, Spinal; Microinjections; Models, Neurological; Neurons; Norepinephrine; Pain; Pons; Rats; Rats, Inbred Strains; Reflex; Serotonin; Skin Temperature; Stereotaxic Techniques; Substance P; Tyrosine 3-Monooxygenase; Yohimbine | 1992 |
Tissue-specific localization of mitochondrial imidazoline-guanidinium receptive sites.
Topics: Animals; Binding Sites; Dioxanes; Humans; Idazoxan; Imidazoline Receptors; Male; Mitochondria; Rabbits; Receptors, Drug; Yohimbine | 1992 |
Interrelation between alpha 2-adrenoreceptor system and neuropeptide Y in rat nucleus tractus solitarii.
Topics: Animals; Blood Pressure; Clonidine; Dioxanes; Heart Rate; Idazoxan; Immunization, Passive; Kinetics; Male; Medulla Oblongata; Neuropeptide Y; Nordefrin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Delineation of three pharmacological subtypes of alpha 2-adrenoceptor in the rat kidney.
Topics: Animals; Binding, Competitive; Computer Simulation; Dioxanes; Guanabenz; Idazoxan; In Vitro Techniques; Kidney; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Autoradiographic distribution of alpha 2 adrenoceptors, NAIBS, and 5-HT1A receptors in human brain using [3H]idazoxan and [3H]rauwolscine.
Topics: Adult; Autoradiography; Binding Sites; Binding, Competitive; Brain; Dioxanes; Female; Humans; Idazoxan; Male; Middle Aged; Organ Specificity; Receptors, Adrenergic, alpha; Receptors, Serotonin; Tritium; Yohimbine | 1991 |
Do noradrenergic descending tract fibres contribute to the depression of transmission from group II muscle afferents following brainstem stimulation in the cat?
Topics: Adrenergic Fibers; Afferent Pathways; Animals; Brain Stem; Cats; Depression, Chemical; Dioxanes; Electric Stimulation; Evoked Potentials; Idazoxan; Interneurons; Locus Coeruleus; Muscles; Receptors, Adrenergic, alpha; Spinal Cord; Synaptic Transmission; Yohimbine | 1991 |
An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain Stem; Clonidine; Dioxanes; Heart Rate; Idazoxan; Locus Coeruleus; Male; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Characterization of renal alpha-adrenoceptor subtypes in sheep during development.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Binding, Competitive; Dioxanes; Fetus; Idazoxan; Kidney; Kidney Cortex; Prazosin; Receptors, Adrenergic, alpha; Sheep; Yohimbine | 1991 |
Role of ventrolateral medulla in sympatholytic effect of 8-OHDPAT in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; Lumbosacral Region; Male; Medulla Oblongata; Neurons; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System; Sympatholytics; Tetrahydronaphthalenes; Yohimbine | 1991 |
Antidiuretic effect of bremazocine and U-50,488 in rats after alpha 2-adrenoceptor blockade.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Antagonists; Animals; Benzomorphans; Dioxanes; Diuresis; Dose-Response Relationship, Drug; Idazoxan; Male; Naloxone; Pyrrolidines; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Pharmacological studies with the alpha 2-adrenoceptor antagonist midaglizole. Part I: Respiratory and cardiovascular systems.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Pressure; Dioxanes; Dogs; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Idazoxan; Imidazoles; Male; Myocardial Contraction; Regional Blood Flow; Renal Circulation; Respiration; Splanchnic Circulation; Tolbutamide; Yohimbine | 1991 |
Effects of chronic alpha 2-adrenoceptor blockade on platelet and lymphocyte adrenoceptor binding in normal volunteers.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Platelets; Brimonidine Tartrate; Dioxanes; Humans; Idazoxan; Lymphocytes; Male; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Up-Regulation; Yohimbine | 1991 |
Non-adrenergic binding sites for the "alpha 2-antagonist" [3H] idazoxan in rabbit urethral smooth muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Cations; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle, Smooth; Rabbits; Receptors, Adrenergic, alpha; Receptors, Drug; Urethra; Yohimbine | 1991 |
[3H]rauwolscine behaves as an agonist for the 5-HT1A receptors in human frontal cortex membranes.
Topics: Adrenergic alpha-Antagonists; Aged; Dioxanes; Frontal Lobe; GTP-Binding Proteins; Guanine Nucleotides; Humans; Idazoxan; In Vitro Techniques; Kinetics; Membranes; Middle Aged; Mollusk Venoms; Phentolamine; Receptors, Adrenergic, alpha; Receptors, Serotonin; Yohimbine | 1991 |
Contraction-mediating alpha 2-adrenoceptors in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Drug Interactions; Idazoxan; Male; Mice; Muscle Contraction; Neuropeptide Y; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Suramin; Vas Deferens; Yohimbine | 1991 |
Anorectic effect of alpha 2-antagonists in dog: effect of acute and chronic treatment.
Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Blood Glucose; Blood Platelets; Body Weight; Catecholamines; Cell Membrane; Dioxanes; Dogs; Fatty Acids, Nonesterified; Feeding Behavior; Idazoxan; Imidazoles; Insulin; Male; Nadolol; Yohimbine | 1991 |
Effects of alpha 2-adrenoceptor blockade and thyrotropin-releasing hormone (TRH) on the cardiovascular system in the rabbit.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Coronary Circulation; Digestive System Physiological Phenomena; Dioxanes; Female; Idazoxan; Male; Masseter Muscle; Rabbits; Regional Blood Flow; Sympathetic Nervous System; Thyrotropin-Releasing Hormone; Vascular Resistance; Yohimbine | 1991 |
GYKI-12743 a new postsynaptic vascular alpha-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation; Heart Rate; Idazoxan; Phentolamine; Phenylephrine; Pyridazines; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Behavioral and receptor binding analysis of the alpha 2-adrenergic agonist, 5-bromo-6 [2-imidazoline-2-yl amino] quinoxaline (UK-14304): evidence for cognitive enhancement at an alpha 2-adrenoceptor subtype.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Behavior, Animal; Blood Pressure; Brain; Brimonidine Tartrate; Cognition; Dioxanes; Female; Guanfacine; Hypnotics and Sedatives; Idazoxan; Macaca mulatta; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Yohimbine | 1991 |
XAMI and DCDM, agonists at cAMP-associated octopamine receptors in cockroach nerve cord, produce centrally mediated antinociception in mice.
Topics: Adenylyl Cyclase Inhibitors; Administration, Oral; Adrenergic alpha-Antagonists; Analgesics; Animals; Chlorphenamidine; Cyclic AMP; Dioxanes; Drug Interactions; Idazoxan; Imidazoles; In Vitro Techniques; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Mice; Naloxone; Octopamine; Periplaneta; Phenylephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Biogenic Amine; Yohimbine | 1991 |
Selectivity of rilmenidine for the nucleus reticularis lateralis, a ventrolateral medullary structure containing imidazoline-preferring receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Catecholamines; Clonidine; Dioxanes; Electrochemistry; Hemodynamics; Idazoxan; Imidazoline Receptors; Male; Medulla Oblongata; Neurons; Oxazoles; Piperoxan; Rats; Rats, Inbred WKY; Receptors, Drug; Reticular Formation; Rilmenidine; Stereotaxic Techniques; Yohimbine | 1991 |
In vivo modulation of the histamine release in the hypothalamus by adrenoreceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Histamine Release; Hypothalamus; Idazoxan; Male; Norepinephrine; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Clonidine inhibition of potassium-evoked release of glutamate and aspartate from rat cortical synaptosomes.
Topics: Analysis of Variance; Animals; Aspartic Acid; Cerebral Cortex; Clonidine; Dioxanes; gamma-Aminobutyric Acid; Glutamates; Idazoxan; Kinetics; Male; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1991 |
Down-regulation of alpha 2 adrenoceptors in ventrolateral medulla of spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Blood Pressure; Cerebral Cortex; Dioxanes; Down-Regulation; Heart Rate; Hypertension; Idazoxan; Imidazoles; Male; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1991 |
Secretion of growth hormone elicited by intravenous desipramine in the conscious, unrestrained rat.
Topics: Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Growth Hormone; Hypothalamo-Hypophyseal System; Idazoxan; Injections, Intravenous; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Imidazole binding sites in rabbit kidney and forebrain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Clonidine; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Norepinephrine; Parasympathetic Nervous System; Rabbits; Sympathetic Nervous System; Yohimbine | 1991 |
New tools for human fat cell alpha-2A adrenoceptor characterization. Identification on membranes and on intact cells using the new antagonist [3H]RX821002.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adult; Dioxanes; Dioxins; Female; Guanosine Triphosphate; Humans; Idazoxan; In Vitro Techniques; Kinetics; Magnesium; Middle Aged; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1990 |
Differences in the regulation of [3H]idazoxan and [3H]yohimbine binding sites in the rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amitriptyline; Animals; Binding Sites; Brain Chemistry; Dioxanes; Dioxins; Hindlimb; Idazoxan; In Vitro Techniques; Kidney; Kinetics; Norepinephrine; Rabbits; Yohimbine | 1990 |
Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Idazoxan; Male; Pain; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
Binding of [3H]idazoxan and of its methoxy derivative [3H] RX821002 in human fat cells: [3H]idazoxan but not [3H] RX821002 labels additional non-alpha 2-adrenergic binding sites.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Binding Sites; Brimonidine Tartrate; Cell Membrane; Cystamine; Dioxanes; Dioxins; Epinephrine; Female; Humans; Idazoxan; Magnesium Chloride; Phenoxybenzamine; Potassium Chloride; Quinoxalines; Tritium; Yohimbine | 1990 |
Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Cattle; Cerebral Cortex; Dioxanes; Hippocampus; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Tetrahydronaphthalenes; Yohimbine | 1990 |
Non-adrenergic sites for imidazolines are not directly involved in the alpha 2-adrenergic antilipolytic effect of UK 14304 in rat adipocytes.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Bucladesine; Cell Membrane; Colforsin; Dioxanes; Idazoxan; Kinetics; Lipolysis; Phentolamine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
Identification of human platelet alpha 2-adrenoceptors with a new antagonist [3H]-RX821002, a 2-methoxy derivative of idazoxan.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Blood Platelets; Brimonidine Tartrate; Dioxanes; Epinephrine; Humans; Idazoxan; In Vitro Techniques; Kinetics; Male; Membranes; Oxymetazoline; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1990 |
[Selectivity of a new antihypertensive agent, rilmenidine, for imidazoline receptors in the human brain].
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Dioxanes; Humans; Idazoxan; Imidazoline Receptors; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine; Yohimbine | 1990 |
Xylazine enhances porcine myometrial contractility in vitro: possible involvement of alpha 2-adrenoceptors and Ca2+ channels.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channels; Carbachol; Dioxanes; Female; Idazoxan; Myometrium; Prazosin; Receptors, Adrenergic, alpha; Swine; Uterine Contraction; Verapamil; Xylazine; Yohimbine | 1990 |
Alpha 2-adrenoceptor-mediated inhibitory and excitatory effects of detomidine on rat gastric acid secretion.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Gastric Acid; Idazoxan; Imidazoles; In Vitro Techniques; Male; Perfusion; Pylorus; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vagotomy; Yohimbine | 1990 |
Imidazoline-guanidinium receptive site in renal proximal tubule: asymmetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance.
Topics: Amiloride; Animals; Binding Sites; Clonidine; Dioxanes; Dioxins; Idazoxan; Imidazoline Receptors; In Vitro Techniques; Kidney Tubules, Proximal; Magnesium; Male; Potassium; Rabbits; Receptors, Adrenergic, alpha; Receptors, Drug; Yohimbine | 1990 |
Functional coupling of the alpha 2-adrenergic receptor-adenylate cyclase complex in the pregnant human myometrium.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Binding, Competitive; Clonidine; Colforsin; Cyclic AMP; Dioxanes; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Female; GTP-Binding Proteins; Humans; Idazoxan; Myometrium; Norepinephrine; Pertussis Toxin; Pregnancy; Pregnancy Trimester, Third; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella; Yohimbine | 1990 |
An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium.
Topics: Affinity Labels; Allosteric Regulation; Amino Acid Sequence; Animals; Aspartic Acid; Brimonidine Tartrate; Dioxanes; DNA Mutational Analysis; Epinephrine; Idazoxan; In Vitro Techniques; Molecular Sequence Data; Oxymetazoline; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Sodium; Structure-Activity Relationship; Swine; Transfection; Yohimbine | 1990 |
Reserpine induces vascular alpha 2-adrenergic supersensitivity and platelet alpha 2-adrenoceptor up-regulation in dog.
Topics: Adipose Tissue; Animals; Blood Platelets; Blood Pressure; Cardiovascular System; Catecholamines; Cell Membrane; Clonidine; Dioxanes; Dogs; Heart Rate; Idazoxan; Male; Norepinephrine; Posture; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Up-Regulation; Yohimbine | 1990 |
Evidence for the involvement of imidazoline receptors in the central hypotensive effect of rilmenidine in the rabbit.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Cisterna Magna; Dioxanes; Heart Rate; Hemodynamics; Idazoxan; Imidazoline Receptors; Injections; Injections, Intraventricular; Male; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine; Tissue Extracts; Yohimbine | 1990 |
Effects of yohimbine and idazoxan on monoamine metabolites in rat cerebrospinal fluid.
Topics: Amines; Animals; Dioxanes; Dioxins; Homovanillic Acid; Hydroxyindoleacetic Acid; Idazoxan; Male; Methoxyhydroxyphenylglycol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Effects of the alpha 2-antagonist idazoxan on monoaminergic parameters measured in the cerebrospinal fluid of rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dioxins; Dopamine beta-Hydroxylase; Female; Glycols; Homovanillic Acid; Hydroxyindoleacetic Acid; Idazoxan; Male; Methoxyhydroxyphenylglycol; Rabbits; Vanilmandelic Acid; Yohimbine | 1987 |
Alpha-adrenergic effects of dopamine and dobutamine on the coronary circulation.
Topics: Animals; Coronary Circulation; Dioxanes; Dobutamine; Dogs; Dopamine; Hemodynamics; Idazoxan; Propranolol; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Central and peripheral effects of prostaglandin E2 and enprostil on exocrine pancreatic secretion in rats.
Topics: Animals; Dinoprostone; Dioxanes; Dose-Response Relationship, Drug; Enprostil; Idazoxan; Injections, Intraventricular; Male; Pancreas; Pancreatic Juice; Prazosin; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Vagus Nerve; Yohimbine | 1989 |
Estimation of pA2 values at presynaptic alpha 2-autoreceptors in rabbit and rat brain cortex in the absence of autoinhibition.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Kinetics; Male; Nordefrin; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1989 |
Effects of suramin and alpha, beta-methylene ATP indicate noradrenaline-ATP co-transmission in the response of the mouse vas deferens to single and low frequency pulses.
Topics: Adenosine Triphosphate; Animals; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Mice; Muscle, Smooth; Norepinephrine; Prazosin; Suramin; Synaptic Transmission; Vas Deferens; Yohimbine | 1989 |
High affinity binding of 3H rauwolscine and 3H RX781094 to alpha 2 adrenergic receptors and non-stereoselective sites in human and rabbit brain cortex membranes.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Cerebral Cortex; Dioxanes; Dioxins; Epinephrine; Humans; Idazoxan; In Vitro Techniques; Phentolamine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Serotonin; Species Specificity; Stereoisomerism; Tritium; Yohimbine | 1989 |
Intrathecal bradykinin acts presynaptically on spinal noradrenergic terminals to produce antinociception in the rat.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Biogenic Monoamines; Bradykinin; Catecholamines; Catheters, Indwelling; Dioxanes; Endorphins; Hydroxydopamines; Idazoxan; Injections, Spinal; Kallidin; Male; Naloxone; Oxidopamine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reaction Time; Spinal Cord; Yohimbine | 1989 |
Mechanism of dexamphetamine-induced mydriasis in the anaesthetized rat.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Denervation; Dextroamphetamine; Dioxanes; Female; Idazoxan; Male; Methyltyrosines; Oculomotor Nerve; Phenoxybenzamine; Pupil; Rats; Reserpine; Tyrosine 3-Monooxygenase; Urethane; Yohimbine | 1989 |
[3H]idazoxan and some other alpha 2-adrenergic drugs also bind with high affinity to a nonadrenergic site.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Dioxanes; Dioxins; Guanosine Triphosphate; Humans; Idazoxan; Kidney Cortex; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium; Yohimbine | 1989 |
Prolactin (PRL) release-inhibiting properties of the alpha 2 adrenergic receptor antagonist idazoxan: comparison with yohimbine.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Dioxanes; Dioxins; Growth Hormone; Idazoxan; Kinetics; Male; Morphine; Norepinephrine; Prazosin; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Restraint, Physical; Yohimbine | 1989 |
[3H]idazoxan binding at non-alpha 2-adrenoceptors in rabbit adipocyte membranes.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; Dioxins; Idazoxan; In Vitro Techniques; Male; Membranes; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Amiloride interacts with [3H]idazoxan and [3H]rauwolscine binding sites in rabbit urethra.
Topics: Adrenergic alpha-Antagonists; Amiloride; Animals; Dioxanes; Dioxins; Idazoxan; In Vitro Techniques; Male; Rabbits; Receptors, Adrenergic, alpha; Urethra; Yohimbine | 1989 |
Different affinities of alpha 2-agonists for imidazoline and alpha 2-adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; Guanfacine; Guanidine; Guanidines; Idazoxan; Imidazoline Receptors; Male; Oxazoles; Phenylacetates; Rabbits; Receptors, Adrenergic, alpha; Receptors, Drug; Rilmenidine; Yohimbine | 1989 |
Clonidine modulates dopamine cell firing in rat ventral tegmental area.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dopamine; Idazoxan; Male; Neurons; Rats; Tegmentum Mesencephali; Yohimbine | 1989 |
[3H]RX821002: a new tool for the identification of alpha 2A-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Catecholamines; Cell Membrane; Colforsin; Cyclic AMP; Dioxanes; Dioxins; Humans; Idazoxan; Kinetics; Radioligand Assay; Receptors, Adrenergic, alpha; Tumor Cells, Cultured; Yohimbine | 1989 |
Alpha-adrenoceptors and insulin release from pancreatic islets of normal and diabetic rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brimonidine Tartrate; Diabetes Mellitus, Experimental; Dioxanes; Female; Glucose; Idazoxan; Insulin; Islets of Langerhans; Male; Phentolamine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Streptozocin; Yohimbine | 1989 |
Effects of the alpha 2-adrenoceptor antagonists yohimbine and idazoxan on kidney function in intact and diabetes insipidus rats.
Topics: Adrenergic alpha-Antagonists; Animals; Diabetes Insipidus; Dioxanes; Dioxins; Diuresis; Idazoxan; Kidney; Male; Rats; Rats, Brattleboro; Rats, Inbred Strains; Renal Circulation; Yohimbine | 1989 |
Effects of idazoxan, tolazoline, and yohimbine on xylazine-induced respiratory changes and central nervous system depression in ewes.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Gas Monitoring, Transcutaneous; Central Nervous System Depressants; Dioxanes; Female; Idazoxan; Oxygen; Random Allocation; Respiration; Sheep; Thiazines; Tolazoline; Xylazine; Yohimbine | 1989 |
[Selectivity of alpha 2-adrenergic agonists for the imidazoline-guanidine and alpha 2-adrenergic receptors].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Guanfacine; Guanidines; Idazoxan; Kidney Tubules, Proximal; Male; Oxazoles; Phenylacetates; Rabbits; Receptors, Adrenergic, alpha; Rilmenidine; Yohimbine | 1989 |
Effects of pre-junctional alpha-receptor blockade on vascular neuro-effector characteristics in rats on high sodium intake.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Neuromuscular Junction; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptic Transmission; Vascular Resistance; Yohimbine | 1989 |
Unmasking sensitive alpha 2-adrenoceptor-mediated renal vasoconstriction in conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Guanabenz; Guanidines; Idazoxan; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Yohimbine | 1989 |
The alpha 2-adrenoceptor antagonists idazoxan and yohimbine can unmask the postsynaptic dopamine agonist effects of B-HT 920.
Topics: Animals; Azepines; Dioxanes; Dioxins; Dopamine Agents; Idazoxan; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Yohimbine | 1989 |
Imidazolinic radioligands for the identification of hamster adipocyte alpha 2-adrenoceptors.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cricetinae; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Kinetics; Lipid Metabolism; Lipolysis; Male; Mesocricetus; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
Different roles of alpha-noradrenergic receptor subtypes in regulating lordosis.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dioxins; Estradiol; Female; Guinea Pigs; Idazoxan; Posture; Prazosin; Progesterone; Receptors, Adrenergic, alpha; Sexual Behavior, Animal; Yohimbine | 1989 |
[Interaction of rilmenidine with renal imidazoline-guanidine sites].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Basement Membrane; Binding Sites; Dioxanes; Drug Interactions; Guanfacine; Guanidines; Idazoxan; Imidazoles; Imidazoline Receptors; Kidney; Male; Oxazoles; Phenylacetates; Rabbits; Receptors, Drug; Rilmenidine; Sodium Channels; Yohimbine | 1989 |
Pharmacological properties of the norepinephrine-induced depolarization of astrocytes in primary culture: evidence for the involvement of an alpha 1-adrenergic receptor.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Dioxanes; Idazoxan; Kinetics; Membrane Potentials; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Classification of phenoxybenzamine/prazosin-resistant contractions of rat spleen to norepinephrine by Schild analysis: similarities and differences to postsynaptic alpha-2 adrenoceptors.
Topics: Alkylation; Animals; Dioxanes; Drug Resistance; Idazoxan; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spleen; Yohimbine | 1988 |
Electrophysiological effects of locally applied noradrenergic agents at cerebellar Purkinje neurons: receptor specificity.
Topics: Action Potentials; Animals; Dioxanes; Dioxins; Idazoxan; Neural Inhibition; Norepinephrine; Phencyclidine; Phentolamine; Purkinje Cells; Rats; Rats, Inbred F344; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1988 |
Idazoxan and brain alpha 2-adrenoceptors in the rabbit.
Topics: Animals; Brain; Clonidine; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Injections, Intravenous; Rabbits; Receptors, Adrenergic, alpha; Time Factors; Yohimbine | 1988 |
Studies on the mechanism of prazosin induced sympatho-inhibition.
Topics: Adrenergic Fibers; Amines; Animals; Cats; Central Nervous System; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hypothalamus, Posterior; Idazoxan; Prazosin; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1988 |
Studies of alpha 2-adrenoceptor antagonist potency in vitro: comparisons in tissues from rats, rabbits, dogs and humans.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dioxanes; Dogs; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Quinolizines; Rabbits; Rats; Rats, Inbred Strains; Saphenous Vein; Species Specificity; Vas Deferens; Yohimbine | 1985 |
Comparison of the effects of recently developed alpha 2-adrenergic antagonists with yohimbine and rauwolscine on monoamine synthesis in rat brain.
Topics: 4-Butyrolactone; Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dioxanes; Idazoxan; Male; Mianserin; Norepinephrine; Quinolizines; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1985 |
Interaction between the inhibitory action of acetylcholine and the alpha-adrenoceptor autoinhibitory feedback system on release of [3H]-noradrenaline from rat atria and rabbit ear artery.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Arteries; Catecholamines; Clonidine; Dioxanes; Ear; Electric Stimulation; Feedback; Female; Heart Atria; Idazoxan; Imidazolines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Norepinephrine; Phentolamine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
The effect of yohimbine, WY 26392 and idazoxan on sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Cats; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Heart Rate; Idazoxan; Male; Quinolizines; Sympathetic Nervous System; Yohimbine | 1985 |
Discriminative stimulus properties of xylazine in rat: discriminability and effects of putative alpha-2 adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Discrimination Learning; Idazoxan; Lisuride; Lysergic Acid Diethylamide; Male; Piperoxan; Rats; Rats, Inbred Strains; Thiazines; Xylazine; Yohimbine | 1985 |
Interaction between prejunctional alpha 2-receptors and neuronal transmitter reuptake in small mesenteric arteries from the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Cocaine; Dioxanes; Electric Stimulation; Hydroxydopamines; Idazoxan; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Denervation; Muscle, Smooth, Vascular; Neuromuscular Junction; Neurotransmitter Agents; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Vascular Resistance; Yohimbine | 1985 |
Modulation of peripheral beta-1 and alpha-2 receptor sensitivities by the administration of the tricyclic antidepressant, imipramine, alone and in combination with alpha-2 antagonists to rats.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Dioxanes; Heart Rate; Hydroxydopamines; Idazoxan; Imipramine; In Vitro Techniques; Isoproterenol; Male; Oxidopamine; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1986 |
Responses to norepinephrine resistant to inhibition by alpha and beta adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Resistance; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Nordefrin; Norepinephrine; Receptors, Adrenergic; Reserpine; Yohimbine | 1986 |
Evidence that serotonin receptors are involved in the anticonvulsant effect of yohimbine in mice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Azepines; Clonidine; Dioxanes; Electroshock; Idazoxan; Male; Metergoline; Methysergide; Mice; Quipazine; Receptors, Serotonin; Serotonin Antagonists; Yohimbine | 1986 |
Does alprazolam, in contrast to diazepam, activate alpha 2-adrenoceptors involved in the regulation of rat growth hormone secretion?
Topics: Adrenergic alpha-Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Clonidine; Diazepam; Dioxanes; Growth Hormone; Idazoxan; Kinetics; Male; Rats; Receptors, Adrenergic, alpha; Reserpine; Yohimbine | 1986 |
Heterogeneity between soluble human and rabbit splenic alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Epinephrine; Humans; Idazoxan; Lectins; Oxymetazoline; Phentolamine; Prazosin; Quinolizines; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha; Solubility; Spleen; Sulfhydryl Reagents; Yohimbine | 1986 |
Possible involvement of presynaptic alpha 1-adrenoceptors in the effects of idazoxan and prazosin on 3H-noradrenaline release from tail arteries of SHR.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Dioxins; Electric Stimulation; Idazoxan; Male; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Differential interactions of "prosexual" drugs with 5-hydroxytryptamine1A and alpha 2-adrenergic receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Brain; Dioxanes; Ejaculation; Idazoxan; Imidazoles; Indans; Male; Methoxydimethyltryptamines; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Stimulation, Chemical; Tetrahydronaphthalenes; Yohimbine | 1986 |
The blood pressure effects of alpha-adrenoceptor antagonists injected in the medullary site of action of clonidine: the nucleus reticularis lateralis.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Dioxanes; Female; Idazoxan; Isoquinolines; Male; Medulla Oblongata; Piperazines; Prazosin; Yohimbine | 1987 |
Alpha-2 receptor blockade increases responsiveness of locus coeruleus neurons to excitatory stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Injections, Intravenous; Locus Coeruleus; Male; Neurons; Nicotine; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Yohimbine | 1987 |
Pharmacological evidence for alpha-2 adrenoceptor heterogeneity: differential binding properties of [3H]rauwolscine and [3H]idazoxan in rat brain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Dioxanes; Dioxins; Dopamine; Epinephrine; Idazoxan; Kinetics; Lung; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Spiperone; Tissue Distribution; Yohimbine | 1987 |
Alpha-2 receptors mediate an endogenous noradrenergic suppression of kindling development.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; Kindling, Neurologic; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Possible role of alpha-2-noradrenergic receptors in modulation of sexual behavior in female guinea pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Estradiol; Female; Guinea Pigs; Idazoxan; Methoxamine; Ovariectomy; Phenylephrine; Posture; Progesterone; Receptors, Adrenergic, alpha; Sexual Behavior, Animal; Yohimbine | 1987 |
Evidence for imidazoline binding sites in basolateral membranes from rabbit kidney.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Membrane; Dioxanes; Dioxins; Epithelium; Idazoxan; Imidazoles; Kidney; Phentolamine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Structure-Activity Relationship; Yohimbine | 1987 |
Alpha 2-adrenoceptor antagonists and male sexual behavior: II. Erectile and ejaculatory reflexes.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Ejaculation; Idazoxan; Imidazoles; Male; Penile Erection; Rats; Reflex; Sexual Behavior, Animal; Yohimbine | 1987 |
Alpha 2-adrenoceptor antagonists and male sexual behavior: I. Mating behavior.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Imidazoles; Male; Rats; Sexual Behavior, Animal; Yohimbine | 1987 |
Selected ion monitoring analysis of monoamine metabolites in cerebrospinal fluid. Application to the study of in vivo effects of alpha 2-antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Dioxanes; Female; Gas Chromatography-Mass Spectrometry; Idazoxan; Indicators and Reagents; Male; Rabbits; Reference Values; Yohimbine | 1987 |
Further evidence of noradrenergic regulation of rat hypothalamic estrogen receptor concentration: possible non-functional increase and functional decrease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cytosol; Dioxanes; Female; Hypothalamus; Idazoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Estrogen; Yohimbine | 1987 |
Alpha 2-adrenergic receptors in brown adipose tissue of infant rats--I. Identification and characteristics of binding sites in isolated plasma membranes.
Topics: Adipose Tissue, Brown; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Membrane; Clonidine; Dihydroalprenolol; Dioxanes; Idazoxan; Kinetics; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
The alpha 2-adrenoceptor antagonists idazoxan and yohimbine increase rates of DRL responding in rats.
Topics: Adrenergic alpha-Agonists; Animals; Conditioning, Operant; Dextroamphetamine; Dioxanes; Dioxins; Idazoxan; Imipramine; Male; Mianserin; Rats; Rats, Inbred Strains; Reinforcement Schedule; Yohimbine | 1988 |
Presynaptic alpha 2-adrenoceptors mediate inhibition of cholinergic transmission in rabbit vesical parasympathetic ganglia.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Epinephrine; Ganglia, Parasympathetic; Idazoxan; Rabbits; Receptors, Adrenergic, alpha; Urinary Bladder; Yohimbine | 1987 |
Evidence for non-adrenergic binding sites for [3H]idazoxan in the smooth muscle of rabbit urethra.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Dioxanes; Dioxins; Female; Idazoxan; In Vitro Techniques; Male; Membranes; Muscle, Smooth; Rabbits; Urethra; Yohimbine | 1988 |
Behavioural effects of the alpha 2-adrenoceptor antagonists idazoxan and yohimbine in rats: comparisons with amphetamine.
Topics: Adrenergic alpha-Antagonists; Animals; Conditioning, Operant; Dextroamphetamine; Dioxanes; Dioxins; Discrimination, Psychological; Idazoxan; Male; Rats; Rats, Inbred Strains; Reinforcement Schedule; Yohimbine | 1988 |
Methiothepin enhances the potassium-evoked release of [3H]-noradrenaline in rat pineal gland.
Topics: Animals; Chromatography, High Pressure Liquid; Dibenzothiepins; Dioxanes; Fenclonine; Idazoxan; In Vitro Techniques; Male; Methiothepin; Norepinephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Serotonin Antagonists; Yohimbine | 1987 |
Inhibition by 5,6-dihydroxy-2-dimethylaminotetralin (M7) of noradrenergic neurotransmission in the rabbit hypothalamus: role of alpha-2 adrenoceptors and of dopamine receptors.
Topics: Animals; Dioxanes; Dopamine; Dopamine Antagonists; Drug Synergism; Hypothalamus; Idazoxan; In Vitro Techniques; Naphthols; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sulpiride; Synaptic Transmission; Yohimbine | 1985 |
Alpha-adrenergic receptors in rat skeletal muscle.
Topics: Animals; Binding Sites; Dihydroalprenolol; Dioxanes; Female; Idazoxan; Kinetics; Male; Muscles; Peptidyl-Dipeptidase A; Phentolamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic, alpha; Sarcolemma; Yohimbine | 1986 |
Long-term amitriptyline treatment alters the affinity state of alpha 2 adrenoceptors in rabbit hindbrain.
Topics: Amitriptyline; Animals; Blood Pressure; Body Weight; Brain Stem; Cerebellum; Clonidine; Dioxanes; Epinephrine; Heart Rate; Idazoxan; Male; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Anatomical evidence for alpha-2 adrenoceptor heterogeneity: differential autoradiographic distributions of [3H]rauwolscine and [3H]idazoxan in rat brain.
Topics: Animals; Autoradiography; Brain; Dioxanes; Dioxins; Idazoxan; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tissue Distribution; Yohimbine | 1987 |
Characterization of alpha 2-adrenergic receptors of calf retina membranes by [3H]-rauwolscine and [3H]-RX 781094 binding.
Topics: Animals; Binding, Competitive; Cattle; Dioxanes; Dioxins; Epinephrine; Guanylyl Imidodiphosphate; Idazoxan; Kinetics; Phentolamine; Receptors, Adrenergic, alpha; Retina; Yohimbine | 1987 |
The release of catecholamines from the adrenal medulla and its modulation by alpha 2-adrenoceptors in the anaesthetized dog.
Topics: Adrenal Medulla; Animals; Catecholamines; Clonidine; Dioxanes; Dogs; Dopamine; Electric Stimulation; Epinephrine; Female; Idazoxan; Male; Norepinephrine; Oxymetazoline; Receptors, Adrenergic, alpha; Splanchnic Nerves; Yohimbine | 1987 |
[3H]yohimbine and [3H]idazoxan bind to different sites on rabbit forebrain and kidney membranes.
Topics: Animals; Binding Sites; Brain; Dioxanes; Dioxins; Idazoxan; Kidney; Male; Rabbits; Yohimbine | 1988 |
A possible alpha 2-adrenergic component in the in vivo activity of pirenperone.
Topics: Animals; Dioxanes; Female; Idazoxan; Piperidines; Piperoxan; Postural Balance; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Serotonin Antagonists; Tranquilizing Agents; Xylazine; Yohimbine | 1984 |
In vitro studies with (imidazolinyl-2)-2-benzodioxane-1-4 ((+/-)-170 150), a new potent alpha 2-adrenoceptor blocking agent.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Clonidine; Dioxins; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1982 |
Studies on RX 781094: a selective, potent and specific antagonist of alpha 2-adrenoceptors.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxins; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tyramine; Vas Deferens; Vasoconstriction; Yohimbine | 1983 |
Electrophysiological demonstration of both alpha 2-agonist and antagonist properties of RX 781094.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dioxins; Electrophysiology; Idazoxan; Locus Coeruleus; Male; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
A study of the selectivity and potency of rauwolscine, RX 781094 and RS 21361 as antagonists of alpha-1 and alpha-2 adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxins; Dose-Response Relationship, Drug; Heart Rate; Hypnotics and Sedatives; Idazoxan; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1984 |
Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cocaine; Decerebrate State; Dioxins; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine | 1984 |
Heterogeneity of smooth muscle alpha adrenoceptors in rat tail artery in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1984 |
Neuronal responses to noradrenaline in the cerebral cortex: evidence against the involvement of alpha 2-adrenoceptors.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cerebral Cortex; Dioxanes; Idazoxan; Male; Neurons; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
RX781094 a potent and selective alpha 2-adrenergic antagonist. Effects in adipocytes and hepatocytes.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Cricetinae; Cyclic AMP; Dioxanes; Dioxins; Epinephrine; Idazoxan; In Vitro Techniques; Liver; Prazosin; Rats; Urea; Yohimbine | 1984 |
The actions of noradrenaline on neurones of the rat substantia gelatinosa in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Male; Membrane Potentials; Neurons; Norepinephrine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Spinal Cord; Substantia Gelatinosa; Tetrodotoxin; Yohimbine | 1984 |
Antagonism of xylazine plus chloral hydrate loss of the righting reflex in mice. A simple in vivo procedure for the evaluation of selective alpha 2-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Chloral Hydrate; Dioxanes; Dose-Response Relationship, Drug; Female; Idazoxan; Mice; Motor Activity; Postural Balance; Quinolizines; Reflex; Thiazines; Xylazine; Yohimbine | 1984 |
The alpha adrenoceptor antagonist properties of idazoxan in normal subjects.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Glucose; Blood Pressure; Catecholamines; Dioxanes; Dioxins; Heart Rate; Humans; Idazoxan; Insulin; Insulin Secretion; Male; Nordefrin; Platelet Aggregation; Potassium; Yohimbine | 1984 |
2-Alkyl analogue of idazoxan (RX 781094) with enhanced antagonist potency and selectivity at central alpha 2-adrenoceptors in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Dioxanes; Dioxins; Idazoxan; In Vitro Techniques; Kinetics; Male; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Selectivity and potency of 2-alkyl analogues of the alpha 2-adrenoceptor antagonist idazoxan (RX 781094) in peripheral systems.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dioxanes; Dioxins; Electric Stimulation; Heart Rate; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Muscles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Vas Deferens; Yohimbine | 1984 |
Comparative effects of RX 781094, mianserin, yohimbine, rauwolscine and prazosin in reversing clonidine inhibition of MIX-stimulated lipolysis in hamster isolated white fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Lipolysis; Male; Mianserin; Prazosin; Theophylline; Yohimbine | 1984 |
Lack of involvement of alpha 2-adrenoceptors in the regulation of striatal dopaminergic transmission.
Topics: Acetylcholine; Animals; Clonidine; Corpus Striatum; Dioxins; Dopamine; Idazoxan; Male; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Yohimbine | 1983 |
Evidence that exogenous but not endogenous norepinephrine activates the presynaptic alpha-2 adrenoceptors on serotonergic nerve endings in the rat hypothalamus.
Topics: Animals; Cocaine; Desipramine; Dioxins; Hypothalamus; Idazoxan; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Yohimbine | 1984 |
Dopamine stimulates alpha 2-adrenoceptors on the Anolis melanophore.
Topics: Animals; Apomorphine; Binding, Competitive; Dioxanes; Dopamine; Dose-Response Relationship, Drug; Idazoxan; Lizards; Melanocyte-Stimulating Hormones; Melanophores; Receptors, Adrenergic, alpha; Skin Pigmentation; Sulpiride; Yohimbine | 1983 |
Brain 3,4-dihydroxyphenylethyleneglycol levels are dependent on central noradrenergic neuron activity.
Topics: Animals; Brain; Cerebral Cortex; Clonidine; Dioxins; Electric Stimulation; Glycols; Hippocampus; Idazoxan; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains; Tetrodotoxin; Yohimbine | 1982 |
Dopamine-induced inhibition of endogenous acetylcholine release from the isolated ileal synaptosomal preparations of guinea-pig mediated via alpha-adrenoceptors.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Calcium; Dioxanes; Dopamine; Drug Interactions; Drug Synergism; Female; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Pertussis Toxin; Potassium; Substance P; Synaptosomes; Virulence Factors, Bordetella; Yohimbine | 1994 |
Studies on the protective effect of azepexole on ouabain-induced cardiac arrhythmias and lethality in guinea-pig.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Dioxanes; Female; Guinea Pigs; Heart Rate; Idazoxan; In Vitro Techniques; Male; Ouabain; Reserpine; Yohimbine | 1995 |
Anxiolytic-like effects of yohimbine in the murine plus-maze: strain independence and evidence against alpha 2-adrenoceptor mediation.
Topics: Animals; Anxiety; Behavior, Animal; Clonidine; Dioxanes; Genotype; Idazoxan; Imidazoles; Mice; Mice, Inbred Strains; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
Comparison of the interaction of agmatine and crude methanolic extracts of bovine lung and brain with alpha 2-adrenoceptor binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Binding, Competitive; Brimonidine Tartrate; Cattle; Cerebral Cortex; Clonidine; Dioxanes; Idazoxan; Imidazoles; Lung; Methanol; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Yohimbine | 1995 |
Corynanthine inhibits, while idazoxan potentiates, cardiotoxic effects of ouabain.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Dioxanes; Drug Interactions; Female; Guinea Pigs; Heart Rate; Heart Ventricles; Hemodynamics; Idazoxan; Male; Ouabain; Yohimbine | 1995 |
Alpha-2 adrenergic receptors in the bovine retina. Presence of only the alpha-2D subtype.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Dioxanes; Idazoxan; Pineal Gland; Radioligand Assay; Receptors, Adrenergic, alpha-2; Retina; Yohimbine | 1995 |
Alpha 2 adrenoceptor- and imidazoline-preferring binding sites in the dog kidney.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Dioxanes; Dogs; Idazoxan; Imidazoles; Imidazoline Receptors; Kidney; Male; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 1995 |
Mechanism of sympathoinhibition by imidazolines.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antihypertensive Agents; Benzazepines; Brimonidine Tartrate; Dioxanes; Hemodynamics; Idazoxan; Imidazoles; Oxazoles; Quinoxalines; Rabbits; Rilmenidine; Sympathetic Nervous System; Yohimbine | 1995 |
Elevation of cAMP facilitates noradrenergic transmission in submucous neurons of guinea pig ileum.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Antagonists; Animals; Colforsin; Cyclic AMP; Dioxanes; Electric Stimulation; Ganglia; Guinea Pigs; Idazoxan; Ileum; Membrane Potentials; Microelectrodes; Neurons; Norepinephrine; Phentolamine; Receptors, Purinergic; Synaptic Transmission; Yohimbine | 1993 |
The role of alpha-adrenergic mechanisms within the area postrema in dopamine-induced emesis.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Atropine; Cats; Cerebral Ventricles; Dioxanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Hemicholinium 3; Idazoxan; Injections, Intraventricular; Male; Mecamylamine; Methyltyrosines; Methysergide; Naloxone; Oxidopamine; Prazosin; Reserpine; Tolazoline; Tyrosine 3-Monooxygenase; Vomiting; Yohimbine | 1995 |
The relationship between density of alpha-adrenoceptor binding sites and contractile responses in several porcine isolated blood vessels.
Topics: 5'-Nucleotidase; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Cell Membrane; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Ear, External; Idazoxan; Male; Microscopy, Electron; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Splenic Artery; Structure-Activity Relationship; Swine; Veins; Yohimbine | 1995 |
Recombinant human alpha 2-adrenoceptor subtypes: comparison of [3H]rauwolscine, [3H]atipamezole and [3H]RX821002 as radioligands.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding, Competitive; Buffers; Cell Line; Dioxanes; Humans; Idazoxan; Imidazoles; Kinetics; Mice; Radioligand Assay; Recombinant Proteins; Yohimbine | 1995 |
Spinal nonadrenergic imidazoline receptors do not mediate the antinociceptive action of intrathecal clonidine in the rat.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Binding, Competitive; Clonidine; Dioxanes; Idazoxan; Imidazoline Receptors; Injections, Spinal; Male; Norepinephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Drug; Spinal Cord; Yohimbine | 1995 |
Does [3H]2-methoxy-idazoxan (RX 821002) detect more alpha-2-adrenoceptor agonist high-affinity sites than [3H]rauwolscine? A comparison of nine tissues and cell lines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Line; Dioxanes; Epinephrine; Female; Guinea Pigs; Humans; Idazoxan; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine | 1995 |
Characterization of binding sites for [3H]-idazoxan, [3H]-P-aminoclonidine and [3H]-rauwolscine in the kidney of the dog.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Clonidine; Dioxanes; Dogs; GTP-Binding Proteins; Idazoxan; Imidazoline Receptors; Kidney; Male; Radioligand Assay; Receptors, Drug; Yohimbine | 1994 |
Behavioural evidence that different neurochemical mechanisms underly stretching-yawning and penile erection induced in male rats by SND 919, a new selective D2 dopamine receptor agonist.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Benzothiazoles; Brain Chemistry; Dioxanes; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Idazoxan; Male; Motor Activity; Penile Erection; Phenethylamines; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Sulpiride; Thiazoles; Yawning; Yohimbine | 1993 |
Alpha 2-adrenoceptor blockade, pituitary-adrenal hormones, and agonistic interactions in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Agonistic Behavior; Animals; Berberine; Corticosterone; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Indomethacin; Male; Pituitary-Adrenal System; Rats; Social Behavior; Yohimbine | 1994 |
Vasopressin inhibits food intake in pygmy goats by activation of alpha 1-adrenergic receptors.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Depression, Chemical; Dioxanes; Dose-Response Relationship, Drug; Eating; Female; Goats; Idazoxan; Prazosin; Propranolol; Vasopressins; Yohimbine | 1994 |
Some unusual effects of alpha 2-adrenergic drugs on cortical high voltage spindles in rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cerebral Cortex; Dioxanes; Dose-Response Relationship, Drug; Electrophysiology; Idazoxan; Imidazoles; Male; Rats; Rats, Wistar; Yohimbine | 1994 |
Alpha 2-adrenoceptor-mediated inhibition of bulbospinal barosensitive cells of rat rostral medulla.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Evoked Potentials; gamma-Aminobutyric Acid; Idazoxan; Injections, Intravenous; Iontophoresis; Male; Medulla Oblongata; Neurons; Nordefrin; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 1993 |
Suppressed renal response to 2,6-dimethyl clonidine but not clonidine in one kidney-one clip hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Clonidine; Dioxanes; Disease Models, Animal; Hypertension, Renovascular; Idazoxan; Kidney; Male; Natriuresis; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Drug; Tritium; Yohimbine | 1993 |
Prejunctional alpha 2-adrenoceptors inhibit acetylcholine release from cholinergic nerves in equine airways.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Trachea; Yohimbine | 1993 |
The alpha-2 antagonists idazoxan and rauwolscine but not yohimbine or piperoxan are anxiolytic in the Vogel lick-shock conflict paradigm following intravenous administration.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Clonidine; Conflict, Psychological; Dioxanes; Drinking Behavior; GABA Antagonists; Idazoxan; Infusions, Intravenous; Male; Piperoxan; Rats; Rats, Sprague-Dawley; Yohimbine | 1994 |
Sympathoinhibition by rilmenidine in conscious rabbits: involvement of alpha 2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Catecholamines; Decerebrate State; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Female; Heart Rate; Hemodynamics; Idazoxan; Kidney; Male; Oxazoles; Rabbits; Rilmenidine; Sympathetic Nervous System; Yohimbine | 1993 |
Characterization of [3H]RX821002 binding to alpha-2 adrenergic receptor subtypes.
Topics: Adrenergic alpha-Antagonists; Animals; Cattle; CHO Cells; Cricetinae; Dioxanes; Female; Idazoxan; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine | 1994 |
Infusions of alpha-2 noradrenergic agonists and antagonists into the amygdala: effects on kindling.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Benzazepines; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Functional Laterality; Idazoxan; Infusions, Parenteral; Kindling, Neurologic; Male; Rats; Receptors, Adrenergic, alpha-2; Seizures; Xylazine; Yohimbine | 1993 |
Alpha 2-adrenoceptor binding sites vary along the length of the male reproductive tract: a possible basis for the regional variation in response to field stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; Electric Stimulation; Epididymis; Idazoxan; In Vitro Techniques; Male; Membranes; Muscle Contraction; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vas Deferens; Yohimbine | 1994 |
Similar ligand binding in recombinant human alpha 2 C2-adrenoceptors produced in mammalian, insect and yeast cells.
Topics: Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Cells, Cultured; Chlorpromazine; Dioxanes; Humans; Idazoxan; Immunoblotting; Mammary Neoplasms, Experimental; Mice; Molecular Sequence Data; Moths; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha; Recombinant Proteins; Saccharomyces cerevisiae; Transfection; Tumor Cells, Cultured; Yohimbine | 1994 |
Clonidine enhances astrocytic glutamine uptake by authentic alpha 2-adrenoceptor stimulation.
Topics: Adrenergic alpha-Agonists; Animals; Astrocytes; Cells, Cultured; Clonidine; Dioxanes; Glutamine; Idazoxan; Mice; Receptors, Adrenergic, alpha; Serotonin; Structure-Activity Relationship; Yohimbine | 1994 |
Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Arousal; Cocaine; Dextroamphetamine; Dioxanes; Dopamine; Dopamine Agents; Exploratory Behavior; Idazoxan; Mice; Motor Activity; Orientation; Pentylenetetrazole; Proprioception; Receptors, Dopamine; Synaptic Transmission; Yohimbine | 1994 |
Acute stress-induced hyperinsulinemia in the pertussis toxin-treated rat: possible role of humoral beta-cell-tropic factors.
Topics: Acute Disease; Adrenal Medulla; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Blood Glucose; Culture Techniques; Dioxanes; Hyperinsulinism; Idazoxan; Insulin; Islets of Langerhans; Male; Peptide Fragments; Pertussis Toxin; Prazosin; Rats; Rats, Sprague-Dawley; Stress, Physiological; Virulence Factors, Bordetella; Yohimbine | 1994 |
Effects of neonatal exposure to clonidine on basal and activated central noradrenaline metabolism and in vivo overflow.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Clonidine; Dialysis; Dioxanes; Idazoxan; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Weight Gain; Yohimbine | 1994 |
Species orthologs of the alpha-2A adrenergic receptor: the pharmacological properties of the bovine and rat receptors differ from the human and porcine receptors.
Topics: Animals; Binding Sites; Cattle; Cell Line; Dioxanes; Humans; Idazoxan; Rats; Receptors, Adrenergic, alpha-2; Species Specificity; Swine; Yohimbine | 1994 |
Characterization of imidazoline binding protein(s) solubilized from human brainstem: studies with [3H]idazoxan and [3H]clonidine.
Topics: Binding Sites; Cell Membrane; Cholic Acids; Chromatography, Gel; Clonidine; Dioxanes; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Norepinephrine; Receptors, Drug; Solubility; Tritium; Yohimbine | 1994 |
The effect of alpha 2-adrenoceptor antagonists in isolated globally ischemic rat hearts.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Coronary Circulation; Dioxanes; Heart; Heart Rate; Idazoxan; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardium; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Tolazoline; Ventricular Pressure; Yohimbine | 1994 |
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipramine; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Muscle Contraction; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reserpine; Sulpiride; Yohimbine | 1994 |
Anxiogenic-like effects of yohimbine and idazoxan in two behavioral situations in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Anxiety; Behavior, Animal; Choice Behavior; Clonidine; Conditioning, Classical; Conflict, Psychological; Dioxanes; Flumazenil; Idazoxan; Male; Mice; Yohimbine | 1993 |
Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Blood Proteins; Brimonidine Tartrate; Cell Membrane; Dioxanes; Epinephrine; Humans; Hydroxylation; Idazoxan; In Vitro Techniques; Lipolysis; Male; Platelet Aggregation; Protein Binding; Quinoxalines; Yohimbine | 1993 |
Heterogeneity of alpha-2 adrenoceptors in pregnant rat uterus: identification of subtypes and autoradiographic distribution.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Binding, Competitive; Dioxanes; Female; Idazoxan; Kinetics; Microscopy; Myometrium; Oxidopamine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1993 |
Involvement of alpha 2-receptors in the analgesia induced by transient forebrain ischemia in rats.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Brain; Carotid Artery, Common; Clonidine; Dioxanes; Endorphins; Idazoxan; Ischemic Attack, Transient; Male; Methysergide; Naloxone; Norepinephrine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Serotonin; Synaptic Transmission; Yohimbine | 1993 |
Estradiol attenuates alpha 2-adrenoceptor-mediated inhibition of hypothalamic norepinephrine release.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Dioxanes; Estradiol; Female; Hypothalamus; Idazoxan; Norepinephrine; Ovariectomy; Potassium Chloride; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Species-selective binding of [3H]-idazoxan to alpha 2-adrenoceptors and non-adrenoceptor, imidazoline binding sites in the central nervous system.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Central Nervous System; Cerebral Cortex; Clonidine; Dioxanes; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Humans; Idazoxan; Imidazoline Receptors; In Vitro Techniques; Kinetics; Membranes; Mice; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic, alpha; Receptors, Drug; Species Specificity; Yohimbine | 1993 |
Postjunctional alpha 2-adrenoceptors in blood vessels: effect of age.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Idazoxan; Male; Methoxamine; Norepinephrine; Quinoxalines; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Tail; Vasoconstriction; Yohimbine | 1993 |
Motor and cardiovascular effects of selective alpha 2-adrenoceptor antagonists in the decerebrated rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Decerebrate State; Dioxanes; Electric Stimulation; Female; Heart Rate; Idazoxan; Injections, Spinal; Male; Motor Neurons; Rabbits; Reflex; Retrospective Studies; Sural Nerve; Yohimbine | 1993 |
Alpha 2A adrenoceptors and non-adrenergic idazoxan binding sites in calf brain and retina are distinct from those in human brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cattle; Cell Membrane; Dioxanes; Frontal Lobe; Humans; Idazoxan; Receptors, Adrenergic, alpha; Retina; Species Specificity; Yohimbine | 1993 |
Heterogeneity of the specific imidazoline binding of [3H]idazoxan in the human cerebral cortex.
Topics: Binding Sites; Brain Stem; Cell Membrane; Cerebral Cortex; Clonidine; Dioxanes; Frontal Lobe; Guanylyl Imidodiphosphate; Humans; Idazoxan; Imidazoles; Kinetics; Magnesium Chloride; Tritium; Yohimbine | 1993 |
The prejunctional inhibitory effect of alpha-methylnoradrenaline in the rat vas deferens is not mediated via alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; Imidazoles; Isometric Contraction; Male; Neuromuscular Junction; Nordefrin; Phenoxybenzamine; Phentolamine; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vas Deferens; Vasoconstrictor Agents; Yohimbine | 1995 |
Intrathecal clonidine and tizanidine in conscious dogs: comparison of analgesic and hemodynamic effects.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Blood Pressure; Bradycardia; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; Glycopyrrolate; Heart Rate; Hemodynamics; Idazoxan; Imidazoles; Injections, Spinal; Male; Parasympatholytics; Reaction Time; Sympatholytics; Vagus Nerve; Vasoconstrictor Agents; Wakefulness; Yohimbine | 1996 |
A re-evaluation of the role of alpha 2-adrenoceptors in the anxiogenic effects of yohimbine, using the selective antagonist delequamine in the rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Chlordiazepoxide; Clonidine; Dioxanes; Diphenhydramine; Hypnotics and Sedatives; Idazoxan; Imidazoles; Injections, Subcutaneous; Isoquinolines; Male; Maze Learning; Mydriasis; Naphthyridines; Picrotoxin; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Comparative effects of idazoxan, prazosin, and yohimbine on coronary ligation-induced arrhythmias in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Coronary Vessels; Hemodynamics; Idazoxan; Ligation; Male; Prazosin; Rats; Rats, Inbred SHR; Yohimbine | 1996 |
Antiarrhythmic action of rilmenidine on adrenaline-induced arrhythmia via central imidazoline receptors in halothane-anaesthetized dogs.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics, Inhalation; Animals; Arrhythmias, Cardiac; Blood Pressure; Dogs; Epinephrine; Female; Halothane; Heart Rate; Idazoxan; Imidazoline Receptors; Male; Oxazoles; Receptors, Drug; Rilmenidine; Yohimbine | 1996 |
Alpha 2-adrenoceptor antagonists potentiate acetylcholinesterase inhibitor effects on passive avoidance learning in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Benzazepines; Cholinesterase Inhibitors; Drug Synergism; Galantamine; Idazoxan; Male; Physostigmine; Rats; Rats, Sprague-Dawley; Tacrine; Yohimbine | 1996 |
5-hydroxytryptaminergic receptor-mediated regulation of growth hormone secretion in Holstein steers occurs via alpha 2-adrenergic-dependent and -independent mechanisms.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Clonidine; Cyproheptadine; Dioxanes; Growth Hormone; Growth Hormone-Releasing Hormone; Idazoxan; Imidazoles; In Vitro Techniques; Male; Pituitary Gland, Anterior; Quipazine; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine | 1996 |
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Medetomidine; Muscle Contraction; Nordefrin; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Vasoconstrictor Agents; Xylazine; Yohimbine | 1996 |
Antinociceptive effects of neuropeptide Y and related peptides in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Eating; Gastrointestinal Hormones; Idazoxan; Injections, Intraventricular; Male; Mice; Neuropeptide Y; Nociceptors; Peptide Fragments; Peptide YY; Peptides; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Receptors, Opioid; Yohimbine | 1996 |
alpha 2A/D-Adrenoceptor subtype predominates also in the neonatal rat spinal cord.
Topics: Adrenergic alpha-Agonists; Age Factors; Animals; Animals, Newborn; Female; Idazoxan; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Tritium; Yohimbine | 1996 |
Buffers differentially alter the binding of [3H]rauwolscine and [3H]RX821002 to the alpha-2 adrenergic receptor subtypes.
Topics: Animals; Buffers; CHO Cells; Cricetinae; Humans; Idazoxan; Kinetics; Opossums; Oxymetazoline; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Species Specificity; Yohimbine | 1996 |
Altered thermoregulatory responses to clonidine in streptozotocin-diabetic rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Body Temperature Regulation; Clonidine; Diabetes Mellitus, Experimental; Idazoxan; Male; Rats; Rats, Wistar; Streptozocin; Time Factors; Yohimbine | 1996 |
Antinociceptive effects of oral clonidine and S12813-4 in acute colon inflammation in rats.
Topics: Acute Disease; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Colitis; Female; Formaldehyde; Idazoxan; Oxazoles; Rats; Rats, Sprague-Dawley; Yohimbine | 1996 |
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine | 1996 |
The effect of alpha 2 adrenoceptor blockers on aggressive behavior in mice: implications for the actions of adrenoceptor agents.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Aggression; Animals; Berberine; Idazoxan; Male; Mice; Yohimbine | 1996 |
Effects of clonidine, yohimbine and idazoxan on isolated carotid arteries of dog.
Topics: Animals; Carotid Arteries; Clonidine; Dogs; Idazoxan; In Vitro Techniques; Muscle, Smooth, Vascular; Receptors, Adrenergic, alpha; Vasoconstriction; Yohimbine | 1996 |
Synergistic behavioral interaction between ethanol and clonidine in rats: role of alpha-2 adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Blood Pressure; Clonidine; Drug Synergism; Ethanol; Idazoxan; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Reflex; Yohimbine | 1996 |
The alpha 2-adrenoceptor antagonist idazoxan is an agonist at 5-HT1A autoreceptors modulating serotonin synthesis in the rat brain in vivo.
Topics: Animals; Cerebral Cortex; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Hippocampus; Idazoxan; Male; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists; Yohimbine | 1996 |
Are imidazoline receptors involved in sympathetic neurotransmission in rat vas deferens?
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Idazoxan; Imidazoline Receptors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxazoles; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens; Yohimbine | 1996 |
Binding of new cirazoline derivative to imidazoline receptors from human brain.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Brain; Clonidine; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Kidney; Mitochondria; Photochemistry; Rabbits; Rats; Receptors, Drug; Tritium; Ultraviolet Rays; Yohimbine | 1997 |
A series of novel imidazoline I2-receptor selective Schiff bases of 1-(benzylidenamino)-3,3-dimethylguanidine.
Topics: Animals; Binding, Competitive; Cattle; Cell Membrane; Cerebral Cortex; Epinephrine; Guanidines; Guinea Pigs; Idazoxan; Imidazoles; Imidazoline Receptors; Kidney Cortex; Norepinephrine; Receptors, Adrenergic, alpha; Receptors, Drug; Schiff Bases; Tritium; Yohimbine | 1997 |
Effect of Japanese angelica root extract on pentobarbital-induced sleep in group-housed and socially isolated mice: evidence for the central action.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Drug Interactions; Housing, Animal; Idazoxan; Injections, Intraperitoneal; Male; Methoxamine; Mice; Pentobarbital; Plant Extracts; Plant Roots; Plants, Medicinal; Sleep; Social Isolation; Stress, Physiological; Yohimbine | 1997 |
Effects of moxonidine and clonidine on renal function and blood pressure in anesthetized rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Glomerular Filtration Rate; Idazoxan; Imidazoles; Kidney; Male; Plasma Volume; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium; Water-Electrolyte Balance; Yohimbine | 1997 |
Moxonidine inhibits Na+/H+ exchange in proximal tubule cells and cortical collecting duct.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Female; Fluoresceins; Fluorescent Dyes; Guanidines; Hydrogen-Ion Concentration; Idazoxan; Imidazoles; Kidney Tubules, Collecting; Kidney Tubules, Proximal; LLC-PK1 Cells; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones; Swine; Yohimbine | 1997 |
The influence of chronic treatment with clonidine, yohimbine and idazoxan on morphine withdrawal.
Topics: Adrenergic Agents; Animals; Clonidine; Drug Interactions; Idazoxan; Male; Mice; Morphine; Narcotics; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Yohimbine | 1997 |
Alpha-adrenoceptors in equine digital veins: evidence for the presence of both alpha1 and alpha2-receptors mediating vasoconstriction.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Dopamine; Horses; Idazoxan; In Vitro Techniques; Isometric Contraction; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Veins; Yohimbine | 1997 |
Expression of functional alpha2-adrenergic receptor subtypes in human corpus cavernosum and in cultured trabecular smooth muscle cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Penis; Quinoxalines; Radioisotopes; Receptors, Adrenergic, alpha-2; Ribonucleases; RNA, Messenger; Yohimbine | 1997 |
Presynaptic imidazoline receptors and non-adrenoceptor [3H]-idazoxan binding sites in human cardiovascular tissues.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Animals; Anticonvulsants; Atrial Function; Binding Sites; Binding, Competitive; Electric Stimulation; Female; Guanidines; Heart Atria; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Isoindoles; Male; Middle Aged; Myocardium; Norepinephrine; Pulmonary Artery; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Drug; Tritium; Yohimbine | 1997 |
BU-224 produces spinal antinociception as an agonist at imidazoline I2 receptors.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Dose-Response Relationship, Drug; Electrophysiology; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Drug; Spinal Cord; Synaptic Transmission; Transcutaneous Electric Nerve Stimulation; Yohimbine | 1997 |
Different apparent modes of inhibition of alpha2A-adrenoceptor by alpha2-adrenoceptor antagonists.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Humans; Idazoxan; Quinolizines; Receptors, Adrenergic, alpha-2; Tritium; Tumor Cells, Cultured; Yohimbine | 1997 |
Renal and blood pressure effects of moxonidine and clonidine in spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Aminoacridines; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Idazoxan; Imidazoles; Kidney; Male; Phenformin; Rats; Rats, Inbred SHR; Sodium; Urodynamics; Yohimbine | 1997 |
[3H]RS79948-197 binding to human, rat, guinea pig and pig alpha2A-, alpha2B- and alpha2C-adrenoceptors. Comparison with MK912, RX821002, rauwolscine and yohimbine.
Topics: Adrenergic Agents; Animals; Guinea Pigs; Humans; Idazoxan; Isoquinolines; Naphthyridines; Quinolizines; Rats; Receptors, Adrenergic, alpha-2; Swine; Yohimbine | 1998 |
Characterization of the allosteric interactions between antagonists and amiloride analogues at the human alpha2A-adrenergic receptor.
Topics: Adrenergic alpha-Antagonists; Allosteric Regulation; Amiloride; Animals; CHO Cells; Cricetinae; Humans; Idazoxan; Protein Binding; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine | 1998 |
Hypercapnia-induced long-term depression of respiratory activity requires alpha2-adrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbon Dioxide; Hypercapnia; Hypoglossal Nerve; Idazoxan; Male; Norepinephrine; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Respiratory Mechanics; Vagotomy; Yohimbine | 1998 |
Alpha2-adrenoceptor antagonists enhance responses of dorsal horn neurones to formalin induced inflammation.
Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Formaldehyde; Idazoxan; Imidazoles; Inflammation; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1998 |
Effects of alpha2-adrenoceptor antagonists on metabolic processes of swine: II. Nitrogen balance responses.
Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animal Feed; Animals; Digestion; Dose-Response Relationship, Drug; Ethanolamines; Idazoxan; Injections, Subcutaneous; Linear Models; Male; Nitrogen; Random Allocation; Swine; Yohimbine | 1998 |
Actions of alpha2 adrenoceptor ligands at alpha2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for alpha2A adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; CHO Cells; Cricetinae; Guanfacine; Humans; Idazoxan; Imidazoles; Ligands; Medetomidine; Quinoxalines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Yohimbine | 1998 |
Prejunctional alpha2A-autoreceptors in the human gastric and ileocolic arteries.
Topics: Adrenergic alpha-Antagonists; Aged; Arteries; Autoreceptors; Colon; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastric Mucosa; Humans; Idazoxan; Ileum; In Vitro Techniques; Male; Middle Aged; Neuromuscular Junction; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha-2; Spiro Compounds; Stomach; Tritium; Yohimbine | 1998 |
Inhibition of stress-stimulated colonic propulsion by alpha 2-adrenoceptor antagonists in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Colon; Defecation; Gastrointestinal Motility; Gastrointestinal Transit; Idazoxan; Male; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Stress, Physiological; Yohimbine | 1998 |
Modulation of external pancreatic secretion by endogenous norepinephrine: study with a norepinephrine uptake blocker in the rat.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Deoxyglucose; Electric Stimulation; Fluoxetine; Idazoxan; Kinetics; Male; Norepinephrine; Pancreas; Prazosin; Propranolol; Rats; Rats, Wistar; Vagus Nerve; Yohimbine | 1999 |
Adrenergic sensitivity of the sensory receptors modulating mechanical allodynia in a rat neuropathic pain model.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Causalgia; Clonidine; Idazoxan; Male; Neurons, Afferent; Norepinephrine; Phenylephrine; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Nerves; Sympathectomy; Sympathetic Nervous System; Yohimbine | 1999 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Alpha2-adrenoceptor antagonists evoke endothelium-dependent and -independent relaxations in the isolated rat aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Cyclic GMP; Drug Interactions; Endothelium, Vascular; Idazoxan; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Rabbits; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Yohimbine | 1999 |
Coexpression of imidazoline receptors and alpha 2-adrenoceptors in neuroglial cell line NG 108,15.
Topics: Animals; Binding, Competitive; Cell Membrane; Clonidine; Glioma; Hybrid Cells; Idazoxan; Imidazoline Receptors; Kinetics; Neuroblastoma; Neuroglia; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 1999 |
Transfected cells expressing the three subtypes of alpha 2-adrenergic receptors lack I1-imidazoline binding sites.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; COS Cells; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Radioligand Assay; Receptors, Adrenergic, alpha-2; Receptors, Drug; Recombinant Proteins; Transfection; Yohimbine | 1999 |
Structure of new imidazoline derivatives and their cardiovascular effect in rats.
Topics: Animals; Benzofurans; Blood Pressure; Female; Heart Rate; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Phenoxybenzamine; Rats; Rats, Wistar; Receptors, Drug; Structure-Activity Relationship; Yohimbine | 1999 |
Importance of imidazoline receptors in the cardiovascular responses of clonidine in sinoaortic denervated rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Clonidine; Denervation; Heart Rate; Heart Valves; Idazoxan; Imidazoline Receptors; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Drug; Sinus of Valsalva; Yohimbine | 1999 |
The alpha2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances anti-parkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Antagonists; Animals; Antiparkinson Agents; Brain; Callithrix; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Drug Synergism; Dyskinesias; Female; Idazoxan; Levodopa; Male; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 1999 |
Noradrenaline release from cultured mouse postganglionic sympathetic neurons: autoreceptor-mediated modulation.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cells, Cultured; Electric Stimulation; Ganglia, Sympathetic; Humans; Idazoxan; Kinetics; Mice; Mice, Inbred Strains; Neurons; Norepinephrine; Phenethylamines; Phentolamine; Purinergic P1 Receptor Agonists; Quinoxalines; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine | 1999 |
Adrenergic alpha2C-receptors reside in rat striatal GABAergic projection neurons: comparison of radioligand binding and immunohistochemistry.
Topics: Adrenergic alpha-Antagonists; Animals; Antibodies; Autoradiography; Binding, Competitive; Brain Chemistry; Calbindin 1; Calbindin 2; Calbindins; Corpus Striatum; gamma-Aminobutyric Acid; Idazoxan; Immunohistochemistry; Male; Neurons; Norepinephrine; Parvalbumins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; S100 Calcium Binding Protein G; Tissue Fixation; Tritium; Yohimbine | 1999 |
Non-adrenergic binding of [3H]atipamezole in rat kidney--regional distribution and comparison to alpha2-adrenoceptors.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Female; Idazoxan; Imidazoles; Kidney; Male; Membranes; Monoamine Oxidase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine | 1999 |
Clozapine reversal of the deficits in coordinated movement induced by D2 receptor blockade does not depend upon antagonism of alpha2 adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Ataxia; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Idazoxan; Loxapine; Male; Muscarinic Antagonists; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Scopolamine; Yohimbine | 1999 |
Ligand recognition of serine-cysteine amino acid exchanges in transmembrane domain 5 of alpha2-adrenergic receptors by UK 14,304.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Cricetinae; Cysteine; Dopamine Antagonists; Humans; Idazoxan; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Oxymetazoline; Protein Structure, Tertiary; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Sequence Homology, Amino Acid; Serine; Transfection; Tritium; Yohimbine | 2000 |
Investigation on the mechanism involved in the effects of agmatine on ethanol-induced gastric mucosal injury in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Central Nervous System Depressants; Ethanol; Female; Gastrointestinal Hemorrhage; Idazoxan; Imidazoline Receptors; Intestinal Mucosa; Male; Nitric Oxide; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Stomach Ulcer; Yohimbine | 2000 |
Synthesis and alpha-adrenergic binding ligand affinities of 2-iminoimidazolidine derivatives.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Idazoxan; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Spectrophotometry, Infrared; Yohimbine | 2000 |
Inverse agonism at alpha(2)-adrenoceptors in native tissue.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Guanosine Triphosphate; Idazoxan; Kinetics; Protein Binding; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine | 2000 |
Norepinephrine release from spinal synaptosomes: auto-alpha2 -adrenergic receptor modulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blotting, Western; Clonidine; Idazoxan; Male; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Synaptosomes; Transfection; Yohimbine | 2000 |
Adrenoceptors in normal and malignant human melanocytes.
Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Idazoxan; Melanocytes; Metoprolol; Oxathiins; Propanolamines; Propranolol; Receptors, Adrenergic; Tumor Cells, Cultured; Yohimbine | 2000 |
Imidazoline receptor antisera-selected (IRAS) cDNA: cloning and characterization.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Blotting, Western; CHO Cells; Clonidine; Cloning, Molecular; COS Cells; Cricetinae; DNA, Complementary; Epinephrine; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Immune Sera; Iodine Radioisotopes; Molecular Sequence Data; Naphazoline; Receptors, Drug; Ruthenium Red; Sequence Tagged Sites; Staining and Labeling; Transfection; Yohimbine | 2000 |
A correlation between dexmedetomidine-induced biphasic increases in free cytosolic calcium concentration and energy metabolism in astrocytes.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Cytosol; Dantrolene; Dexmedetomidine; Dose-Response Relationship, Drug; Energy Metabolism; Hypnotics and Sedatives; Idazoxan; Mice; Muscle Relaxants, Central; Pyruvic Acid; Yohimbine | 2000 |
Nonnoradrenergic mechanism of reflex cutaneous vasoconstriction in men.
Topics: Adrenergic alpha-Antagonists; Blood Pressure; Forearm; Humans; Idazoxan; Laser-Doppler Flowmetry; Male; Norepinephrine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Regional Blood Flow; Skin; Skin Temperature; Vasoconstriction; Yohimbine | 2001 |
Agonist trafficking of G(i/o)-mediated alpha(2A)-adrenoceptor responses in HEL 92.1.7 cells.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Biological Transport; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Idazoxan; Pertussis Toxin; Propranolol; Receptors, Adrenergic, alpha-2; Tumor Cells, Cultured; Virulence Factors, Bordetella; Yohimbine | 2001 |
The differential effects of prenatal stress in rats on the acoustic startle reflex under baseline conditions and in response to anxiogenic drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Idazoxan; Isoquinolines; Male; Naphthyridines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stress, Physiological; Yohimbine | 2001 |
The alpha 2 adrenoceptor antagonists RX 821002 and yohimbine delay-dependently impair choice accuracy in a delayed non-matching-to-position task in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Idazoxan; Male; Muscarinic Antagonists; Psychomotor Performance; Rats; Scopolamine; Yohimbine | 2001 |
Evidence for alpha-2 adrenoreceptor modulation of arterial chemoreflexes in the caudal solitary nucleus of the rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Arteries; Blood Pressure; Carotid Sinus; Chemoreceptor Cells; Denervation; Excitatory Amino Acid Antagonists; Idazoxan; Kynurenic Acid; Male; Microinjections; Poisons; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Respiratory Physiological Phenomena; Solitary Nucleus; Vagotomy; Yohimbine | 2001 |
Pre- and postjunctional alpha(2)-adrenergic receptors in fetal and adult ovine cerebral arteries.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Animals; Binding, Competitive; Brimonidine Tartrate; Cerebral Arteries; Clonidine; Dose-Response Relationship, Drug; Female; Fetus; Idazoxan; Middle Cerebral Artery; Norepinephrine; Phenylephrine; Pregnancy; Quinoxalines; Receptors, Adrenergic, alpha-2; Sheep; Tetrodotoxin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 2002 |
Inhibition of pilocarpine-induced salivation in rats by central noradrenaline.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Idazoxan; Injections, Intraperitoneal; Injections, Intraventricular; Male; Muscarinic Agonists; Norepinephrine; Pilocarpine; Prazosin; Rats; Rats, Sprague-Dawley; Saliva; Salivation; Statistics as Topic; Yohimbine | 2002 |
Involvement of I(1)-imidazoline receptors in baroreceptor reflex in the caudal ventrolateral medulla of rats.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Baroreflex; Blood Pressure; Electric Stimulation; Electrocardiography; Electrophysiology; Glutamic Acid; Heart Rate; Hemodynamics; Idazoxan; Imidazoline Receptors; Male; Medulla Oblongata; Microinjections; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Stereotaxic Techniques; Synaptic Transmission; Yohimbine | 2003 |
Central alpha(2) adrenergic receptors and cholinergic-induced salivation in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Idazoxan; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Male; Muscarinic Agonists; Pilocarpine; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Salivation; Sympatholytics; Yohimbine | 2003 |
Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Arteries; Azepines; Brimonidine Tartrate; Clonidine; Idazoxan; In Vitro Techniques; Ligands; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxazoles; Prostaglandins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Rilmenidine; Yohimbine | 2002 |
Regional distribution of alpha(2C)-adrenoceptors in brain and spinal cord of control mice and transgenic mice overexpressing the alpha(2C)-subtype: an autoradiographic study with [(3)H]RX821002 and [(3)H]rauwolscine.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brain; Female; Idazoxan; Mice; Mice, Inbred Strains; Mice, Transgenic; Neurons; Norepinephrine; Radioligand Assay; Receptors, Adrenergic, alpha-2; Spinal Cord; Synaptic Transmission; Tritium; Up-Regulation; Yohimbine | 2003 |
Spinal antinociceptive effect of agmatine and tentative analysis of involved receptors: study in an electrophysiological model of rats.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Agmatine; Analgesics; Animals; Dose-Response Relationship, Drug; Electrophysiology; Female; Idazoxan; Injections, Spinal; Intralaminar Thalamic Nuclei; Male; Neural Pathways; Neurons; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Tail; Yohimbine | 2003 |
Dual effect of agmatine in the bisected rat vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Epididymis; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Potassium Chloride; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens; Yohimbine | 2003 |
Role of I1-imidazoline receptors within the caudal ventrolateral medulla in cardiovascular responses to clonidine in rats.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Idazoxan; Imidazoline Receptors; Injections, Intravenous; Male; Medulla Oblongata; Microelectrodes; Microinjections; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Drug; Yohimbine | 2003 |
Identification and characterization of the imidazoline I2b-binding sites in the hamster brown adipose tissue as a study model for imidazoline receptors.
Topics: Adipose Tissue, Brown; Amiloride; Animals; Binding Sites; Binding, Competitive; Cell Line, Tumor; Clonidine; Culture Techniques; Dose-Response Relationship, Drug; Guanabenz; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Liver; Mammary Neoplasms, Animal; Mice; Protein Binding; Rats; Receptors, Drug; Species Specificity; Yohimbine | 2003 |
Agmatine inhibits naloxone-induced contractions in morphine-dependent Guinea pig ileum.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine | 2003 |
Inhibitory effect of harmane on morphine-dependent Guinea pig ileum.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Guinea Pigs; Harmine; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine | 2003 |
Involvement of forebrain imidazoline and alpha(2)-adrenergic receptors in the antidipsogenic response to moxonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Drinking; Idazoxan; Imidazoles; Imidazoline Receptors; Injections, Intraventricular; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Water Deprivation; Yohimbine | 2003 |
Moxonidine and rilmenidine injected into the medial septal area reduces the salivation induced by pilocarpine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Drug Interactions; Idazoxan; Imidazoles; Male; Muscarinic Agonists; Oxazoles; Pilocarpine; Rats; Rats, Sprague-Dawley; Rilmenidine; Salivation; Septum of Brain; Yohimbine | 2004 |
[Ethyl-3H]RS-79948-197 alpha2-adrenoceptor autoradiography validation in alpha2-adrenoceptor knockout mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Autoradiography; Binding Sites; Binding, Competitive; Cerebral Cortex; Idazoxan; In Vitro Techniques; Isoquinolines; Ligands; Mice; Mice, Knockout; Naphthyridines; Oxymetazoline; Phentolamine; Prazosin; Putamen; Radioligand Assay; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine | 2004 |
Noradrenergic inputs mediate state dependence of auditory responses in the avian song system.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Arousal; Auditory Perception; Clonidine; Dose-Response Relationship, Drug; Finches; Guanabenz; Idazoxan; Imidazoles; Isoproterenol; Male; Norepinephrine; Oxathiins; Phenylephrine; Propanolamines; Prosencephalon; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Vocalization, Animal; Yohimbine | 2004 |
Long-lasting effects of yohimbine on the ejaculatory function in male dogs.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Ejaculation; Idazoxan; Male; Penile Erection; Sexual Behavior, Animal; Time Factors; Yohimbine | 2005 |
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Narcotic Antagonists; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sciatic Nerve; Spinal Cord; Touch; Yohimbine | 2006 |
Involvement of I2-imidazoline binding sites in positive and negative morphine analgesia modulatory effects.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Benzofurans; CHO Cells; Cricetinae; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Mice; Models, Molecular; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Radioligand Assay; Reaction Time; Receptors, Adrenergic, alpha-2; Receptors, Drug; Receptors, Opioid, mu; Yohimbine | 2006 |
Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Cocaine; Idazoxan; Male; Motor Activity; Prazosin; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine | 2006 |
Agmatine and a cannabinoid agonist, WIN 55212-2, interact to produce a hypothermic synergy.
Topics: Adrenergic alpha-Antagonists; Agmatine; Animals; Benzoxazines; Body Temperature; Cannabinoid Receptor Agonists; Cannabinoids; Dose-Response Relationship, Drug; Drug Synergism; Hypothermia; Idazoxan; Imidazoline Receptors; Injections, Intraventricular; Male; Morpholines; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptors, Drug; Yohimbine | 2006 |
Agmatine blocks morphine-evoked hyperthermia in rats.
Topics: Agmatine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Biogenic Amines; Body Temperature Regulation; Dose-Response Relationship, Drug; Drug Interactions; Fever; Idazoxan; Imidazoline Receptors; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Drug; Receptors, Opioid, mu; Yohimbine | 2007 |
Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells.
Topics: Adrenergic alpha-Antagonists; Agmatine; Aniline Compounds; Arginine; Calcium; Calcium Channel Blockers; Cell Culture Techniques; Cells, Cultured; Culture Media, Serum-Free; Dexmedetomidine; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Estrenes; Fluorescent Dyes; Humans; Idazoxan; Imidazolines; Lipopolysaccharides; Molecular Structure; NG-Nitroarginine Methyl Ester; Nifedipine; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Pyrrolidinones; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Type C Phospholipases; Umbilical Veins; Virulence Factors, Bordetella; Xanthenes; Yohimbine | 2007 |
Imidazoline I(1) receptor-mediated reduction of muscle rigidity in the reserpine-treated murine model of Parkinson's disease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzazepines; Benzofurans; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Idazoxan; Imidazoles; Imidazoline Receptors; Injections, Intraperitoneal; Ligands; Male; Mice; Muscle Rigidity; Muscle, Skeletal; Parkinsonian Disorders; Reserpine; Time Factors; Yohimbine | 2008 |
[5-HT1A/1B receptors, alpha2-adrenoceptors and the post-receptor adenylate cyclase activation in the mice brain are involved in the antidepressant-like action of agmatine].
Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Agmatine; Animals; Antidepressive Agents; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Fenclonine; Idazoxan; Male; Mice; Pindolol; Random Allocation; Rats; Rats, Wistar; Receptors, Biogenic Amine; Serotonin 5-HT1 Receptor Antagonists; Swimming; Synapses; Yohimbine | 2008 |
Low doses of alpha 2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Idazoxan; Imidazoles; Male; Mianserin; Mirtazapine; Morphine; Rats; Rats, Sprague-Dawley; Spine; Yohimbine | 2008 |
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2009 |
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Idazoxan; Imidazoles; Leucine; Male; Naloxone; Opioid Peptides; Pain; Pain Measurement; Rats; Rats, Wistar; Xylazine; Yohimbine | 2009 |
Agmatine enhances cannabinoid action in the hot-plate assay of thermal nociception.
Topics: Adrenergic alpha-Antagonists; Agmatine; Animals; Benzoxazines; Cannabinoids; Dose-Response Relationship, Drug; Drug Synergism; Hot Temperature; Idazoxan; Imidazoline Receptors; Male; Morpholines; Naphthalenes; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Adrenergic, alpha-2; Yohimbine | 2009 |
α2-adrenergic drugs modulate the binding of [18F]fallypride to dopamine D2/3 receptors in striatum of living mouse.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzamides; Binding, Competitive; Brain Mapping; Clonidine; Corpus Striatum; Dopamine; Female; Idazoxan; Mice; Mice, Inbred BALB C; Positron-Emission Tomography; Pyrrolidines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Yohimbine | 2010 |
Repeated agmatine treatment attenuates nicotine sensitization in mice: modulation by alpha2-adrenoceptors.
Topics: Agmatine; Animals; Arginine; Biguanides; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Enzyme Inhibitors; Guanidines; Idazoxan; Male; Mice; Motor Activity; Nicotine; Receptors, Adrenergic, alpha-2; Yohimbine | 2010 |
Alpha2-adrenoceptor blockade potentiates the effect of duloxetine on sneeze induced urethral continence reflex in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Drug Synergism; Duloxetine Hydrochloride; Female; Idazoxan; Rats; Rats, Sprague-Dawley; Reflex; Selective Serotonin Reuptake Inhibitors; Sneezing; Thiophenes; Urethra; Urinary Incontinence, Stress; Yohimbine | 2010 |
Determination of α(2)-adrenoceptor and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by agmatine and BMS182874.
Topics: Agmatine; Analgesics; Animals; Dansyl Compounds; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Oxycodone; Receptors, Adrenergic, alpha-2; Receptors, Endothelin; Yohimbine | 2011 |
Study of adrenergic, imidazoline, and endothelin receptors in clonidine-, morphine-, and oxycodone-induced changes in rat body temperature.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Body Temperature; Body Temperature Regulation; Brain; Clonidine; Dansyl Compounds; Drug Synergism; Endothelin A Receptor Antagonists; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Yohimbine | 2011 |
Inhibition of sodium appetite by lipopolysaccharide: involvement of alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Appetite; Blood Pressure; Body Temperature; Dose-Response Relationship, Drug; Gastric Emptying; Heart Rate; Idazoxan; Injections, Intraperitoneal; Lipopolysaccharides; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium Chloride, Dietary; Yohimbine | 2011 |
Morphine-induced antinociception in the rat: supra-additive interactions with imidazoline I₂ receptor ligands.
Topics: Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Yohimbine | 2011 |
Assessment of the analgesic effect of centhaquin in mouse tail flick and hot-plate tests.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Antihypertensive Agents; Body Temperature; Drug Interactions; Endothelin A Receptor Antagonists; Hot Temperature; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain; Piperazines; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine | 2011 |
Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Drug Interactions; Ethanolamines; Idazoxan; Male; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Thymine; Vasoconstriction; Xylazine; Yohimbine | 2012 |
Effects of noradrenergic alpha-2 receptor antagonism or noradrenergic lesions in the ventral bed nucleus of the stria terminalis and medial preoptic area on maternal care in female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antibodies, Monoclonal; Dose-Response Relationship, Drug; Female; Idazoxan; Maternal Behavior; Ovariectomy; Postpartum Period; Preoptic Area; Rats; Rats, Long-Evans; Ribosome Inactivating Proteins, Type 1; Saporins; Septal Nuclei; Yohimbine | 2012 |
Involvement of α₂-adrenoceptors, imidazoline, and endothelin-A receptors in the effect of agmatine on morphine and oxycodone-induced hypothermia in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Agmatine; Animals; Body Temperature Regulation; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Hypothermia; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Oxycodone; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Yohimbine | 2013 |
Commissural nucleus of the solitary tract regulates the antihypertensive effects elicited by moxonidine.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Consciousness; Fourth Ventricle; Heart Rate; Idazoxan; Imidazoles; Injections; Injections, Intraventricular; Male; Neurons; Rats; Rats, Inbred SHR; Rats, Wistar; Solitary Nucleus; Stereotaxic Techniques; Yohimbine | 2013 |
Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Binding Sites; Drug Synergism; Female; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Quinazolines; Rats, Sprague-Dawley; Yohimbine | 2014 |