Compounds > idazoxan
Page last updated: 2024-08-23

idazoxan and pentamidine

idazoxan has been researched along with pentamidine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Hall, JE; Rose, BG; Tidwell, RR; Wood, DH1
Boykin, DW; Hall, JE; Rose, BG; Tidwell, RR; Wood, DH1

Other Studies

5 other study(ies) available for idazoxan and pentamidine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
1,5-Bis(4-amidinophenoxy)pentane (pentamidine) is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 binding sites.
    European journal of pharmacology, 1998, Jul-17, Volume: 353, Issue:1

    Topics: Animals; Antifungal Agents; Binding, Competitive; Drug Evaluation, Preclinical; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Liver; Male; Membranes; Pentamidine; Pneumonia, Pneumocystis; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Drug; Structure-Activity Relationship

1998
Pentamidine is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 receptors.
    Annals of the New York Academy of Sciences, 1999, Jun-21, Volume: 881

    Topics: Animals; Anti-Infective Agents; Binding Sites; Binding, Competitive; Cell Membrane; Cryptosporidium; Idazoxan; Imidazoline Receptors; Kinetics; Liver; Pentamidine; Pneumocystis; Radioligand Assay; Rats; Receptors, Drug

1999