idazoxan has been researched along with morphine in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.33) | 18.7374 |
| 1990's | 16 (35.56) | 18.2507 |
| 2000's | 13 (28.89) | 29.6817 |
| 2010's | 10 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mammoli, V; Mattioli, L; Perfumi, M; Piergentili, A; Pigini, M; Quaglia, W; Titomanlio, F | 1 |
| Beani, L; Bianchi, C; Guidorzi, R; Tomasini, C | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Simonato, M; Spalluto, P; Tanganelli, S; Tomasini, C | 1 |
| Jurcovicová, J; Krulich, L; Le, T | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Rando, S; Simonato, M; Tanganelli, S | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; McWilliam, JR | 2 |
| Brown, MJ; Conway, EL; Dollery, CT | 1 |
| Lester, BR; Sun, Z; Wilcox, GL; Wu, HH | 1 |
| Dickenson, AH; Stanfa, LC | 1 |
| Barturen, F; García-Sevilla, JA; García-Vallejo, P | 1 |
| Bouaziz, H; Eisenach, JC; Hood, DD; Tong, C; Yoon, Y | 1 |
| Nozaki-Taguchi, N; Yamamoto, T | 1 |
| El-Kadi, AO; Sharif, SI | 1 |
| Fang, F; Proudfit, HK | 1 |
| Eisenach, JC; Pan, HL; Song, HK | 1 |
| Mason, R; Mundey, MK; Wilson, VG | 1 |
| Boronat, MA; García-Sevilla, JA; Olmos, G | 2 |
| Fukuhara, N; Ishikawa, T; Kinoshita, H; Nakanishi, O; Xiong, L | 1 |
| Ahtee, L; Airio, J | 1 |
| Li, J; Li, X; Pei, G; Qin, BY | 2 |
| Freedman, JE; Murphy, R | 1 |
| Gao, K; Li, J; Pei, G; Qin, BY; Su, RB | 1 |
| Li, J; Li, X; Qin, BY; Su, RB | 1 |
| Li, J; Lu, G; Qin, BY; Su, RB | 1 |
| Aricioglu, F; Dulger, G; Ercil, E | 1 |
| Aricioglu, F; Utkan, T | 1 |
| Cardinaletti, C; Carrieri, A; Gentili, F; Ghelfi, F; Mattioli, L; Perfumi, M; Pigini, M; Vesprini, C | 1 |
| Curry, R; DeGoes, S; Eisenach, JC; Hayashida, K | 1 |
| Amin, M; Rawls, SM; Zisk, J | 1 |
| Li, J; Lu, XQ; Su, RB; Wei, XL; Wu, N; Zheng, JQ | 1 |
| Cahill, CM; Jhamandas, K; Milne, B; Sutak, M | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A; Matwyshyn, G; Zhang, Z | 1 |
| Bi, GH; Dong, HJ; Li, J; Lu, W; Su, RB; Yang, Z; Zhao, YQ | 1 |
| Dong, HJ; Gong, ZH; Li, J; Lu, W; Su, RB | 1 |
| Bhalla, S; Gulati, A; Rapolaviciute, V | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A | 2 |
| Li, JX; Winter, JC; Zhang, Y | 1 |
| Andurkar, SV; Gulati, A | 1 |
| Caselli, G; Ferrari, F; Lanza, M; Menghetti, I; Tremolada, D | 1 |
1 trial(s) available for idazoxan and morphine
| Article | Year |
|---|---|
Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery.
Topics: Adrenergic alpha-Antagonists; Amines; Analgesics; Analgesics, Opioid; Animals; Bee Venoms; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Idazoxan; Male; Morphine; Norepinephrine; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerve Roots; Time Factors | 2007 |
44 other study(ies) available for idazoxan and morphine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Humans; Idazoxan; Imidazolines; Male; Mice; Morphine; Pain Measurement; Receptors, Adrenergic, alpha-2; Stereoisomerism | 2012 |
Clonidine inhibition of norepinephrine release from normal and morphine-tolerant guinea pig cortical slices.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Dioxanes; Drug Tolerance; Electric Stimulation; Female; Guinea Pigs; Idazoxan; In Vitro Techniques; Male; Morphine; Norepinephrine; Receptors, Adrenergic, alpha; Receptors, Opioid; Reference Values | 1992 |
Changes in cortical acetylcholine and gamma-aminobutyric acid outflow during morphine withdrawal involve alpha-1 and alpha-2 receptors.
Topics: Acetylcholine; Animals; Clonidine; Dioxanes; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Naloxone; Prazosin; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome | 1989 |
Prolactin (PRL) release-inhibiting properties of the alpha 2 adrenergic receptor antagonist idazoxan: comparison with yohimbine.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Dioxanes; Dioxins; Growth Hormone; Idazoxan; Kinetics; Male; Morphine; Norepinephrine; Prazosin; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Restraint, Physical; Yohimbine | 1989 |
Inversion of the alpha-2 and alpha-1 noradrenergic control of the cortical release of acetylcholine and gamma-aminobutyric acid in morphine-tolerant guinea pigs.
Topics: Acetylcholine; Animals; Cerebral Cortex; Clonidine; Dioxanes; Drug Tolerance; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha | 1988 |
Synaptosomal free [Ca2+] is reduced by clonidine and dynorphin A-(1-13) and increased by idazoxan.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Calcium; Clonidine; Dioxanes; Dioxins; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Idazoxan; In Vitro Techniques; Male; Morphine; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Synaptosomes | 1987 |
Mutual antagonism of kappa-opiate and alpha 2-adrenoceptor agonist effects on intrasynaptosomal free [Ca2+]i.
Topics: Aminoquinolines; Animals; Calcium; Cerebral Cortex; Clonidine; Dioxanes; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fluorescent Dyes; Idazoxan; Male; Morphine; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Synaptosomes | 1988 |
Studies on the pharmacology of central opioid-induced increases in plasma catecholamines in conscious rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Antagonists; Analgesics; Animals; Catecholamines; Dioxanes; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Idazoxan; Injections, Intraventricular; Male; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1984 |
Antinociception following implantation of mouse B16 melanoma cells in mouse and rat spinal cord.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Catecholamines; Cell Transplantation; Desipramine; Dioxanes; Idazoxan; Injections, Spinal; Male; Melanoma, Experimental; Mice; Mice, Inbred ICR; Morphine; Naloxone; Neoplasm Transplantation; Nociceptors; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Substance P; Transplantation, Heterotopic | 1994 |
Enhanced alpha-2 adrenergic controls and spinal morphine potency in inflammation.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Carrageenan; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Idazoxan; Imidazoles; Inflammation; Injections, Spinal; Male; Medetomidine; Morphine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1994 |
Modulation by central postsynaptic alpha 2-adrenoceptors of the jaw-opening reflex induced by orofacial stimulation in rats.
Topics: Amphetamine; Animals; Brain; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; Jaw; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Reserpine | 1994 |
Intravenous opioids stimulate norepinephrine and acetylcholine release in spinal cord dorsal horn. Systematic studies in sheep and an observation in a human.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Dialysis; Dioxanes; Dopamine; Female; Fentanyl; Humans; Idazoxan; Imidazoles; Injections, Intravenous; Male; Microchemistry; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Receptors, Adrenergic, alpha-2; Sheep; Spinal Cord; Stimulation, Chemical | 1996 |
Clonidine, but not morphine, delays the development of thermal hyperesthesia induced by sciatic nerve constriction injury in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; Hyperesthesia; Idazoxan; Ligation; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Sciatic Nerve; Spinal Cord; Sympathetic Nervous System; Temperature; Time Factors | 1996 |
The influence of chronic treatment with clonidine, yohimbine and idazoxan on morphine withdrawal.
Topics: Adrenergic Agents; Animals; Clonidine; Drug Interactions; Idazoxan; Male; Mice; Morphine; Narcotics; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Yohimbine | 1997 |
Antinociception produced by microinjection of morphine in the rat periaqueductal gray is enhanced in the foot, but not the tail, by intrathecal injection of alpha1-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Behavior, Animal; Dioxanes; Female; Foot; Idazoxan; Injections, Spinal; Microinjections; Morphine; Narcotics; Nociceptors; Pain; Periaqueductal Gray; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spinal Cord; Tail | 1998 |
Spinal nitric oxide mediates antinociception from intravenous morphine.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Atropine; Drug Interactions; Enzyme Inhibitors; Idazoxan; Injections, Intravenous; Male; Morphine; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Pain; Rats; Rats, Sprague-Dawley | 1998 |
Selective potentiation by ouabain of naloxone-induced withdrawal contractions of isolated guinea-pig ileum following acute exposure to morphine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Ouabain; Receptors, Adrenergic, alpha-2; Sodium-Potassium-Exchanging ATPase; Substance Withdrawal Syndrome | 1998 |
Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I2-imidazoline ligands.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Benzofurans; Brain; Drug Tolerance; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Neurofilament Proteins; Pain Measurement; Pentazocine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Receptors, N-Methyl-D-Aspartate | 1998 |
Central noradrenergic mediation of nitrous oxide-induced analgesia in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Fibers; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Drug Synergism; Idazoxan; Male; Morphine; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons, Afferent; Nitrous Oxide; Rats; Rats, Wistar; Reaction Time; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Receptors, Presynaptic; Spinal Cord; Synaptic Transmission | 1998 |
The involvement of noradrenergic transmission in the morphine-induced locomotor hyperactivity in mice withdrawn from repeated morphine treatment.
Topics: Animals; Body Weight; Brain Chemistry; Dopamine; Idazoxan; Male; Mice; Morphine; Motor Activity; Norepinephrine; Substance Withdrawal Syndrome | 1999 |
Attenuation of tolerance to opioid-induced antinociception by idazoxan and other I2-ligands.
Topics: Animals; Drug Tolerance; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Pain; Pentazocine; Rats; Rats, Sprague-Dawley; Receptors, Drug | 1999 |
Effects of agmatine on tolerance to and substance dependence on morphine in mice.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Drug Tolerance; Female; Idazoxan; Male; Mice; Morphine; Morphine Dependence; Substance Withdrawal Syndrome | 1999 |
Influence of agmatine in adaptation of cAMP signal transduction system of opiate receptors.
Topics: Adaptation, Physiological; Adrenergic alpha-Antagonists; Agmatine; Analgesics; Animals; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Glioma; Guanosine 5'-O-(3-Thiotriphosphate); Hybrid Cells; Idazoxan; Imidazoline Receptors; Mice; Morphine; Neuroblastoma; Rats; Receptors, Drug; Signal Transduction; Tumor Cells, Cultured | 1999 |
Morphine and clonidine activate different K+ channels on rat amygdala neurons.
Topics: Adrenergic alpha-Antagonists; Amygdala; Analgesics; Animals; Clonidine; Idazoxan; Membrane Potentials; Morphine; Neurons; Patch-Clamp Techniques; Potassium Channels; Rats | 2001 |
Influence of idazoxan on analgesia, tolerance, and physical dependence of morphine in mice and rats in vivo.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Drug Tolerance; Female; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Mice; Morphine; Morphine Dependence; Pain Threshold; Rats; Rats, Wistar; Receptors, Drug | 2000 |
Down-regulation of MAO-B activity and imidazoline receptors in rat brain following chronic treatment of morphine.
Topics: Agmatine; Animals; Brain; Chromatography, High Pressure Liquid; Down-Regulation; Idazoxan; Imidazoline Receptors; Male; Monoamine Oxidase; Morphine; Morphine Dependence; Rats; Rats, Wistar; Receptors, Drug | 2001 |
Modulation by alpha-difluoromethyl-ornithine and aminoguanidine of pain threshold, morphine analgesia and tolerance.
Topics: Acetic Acid; Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Behavior, Animal; Drug Tolerance; Eflornithine; Female; Guanidines; Hot Temperature; Idazoxan; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Morphine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Measurement; Pain Threshold | 2003 |
Agmatine inhibits naloxone-induced contractions in morphine-dependent Guinea pig ileum.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine | 2003 |
Inhibitory effect of harmane on morphine-dependent Guinea pig ileum.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Guinea Pigs; Harmine; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine | 2003 |
Involvement of I2-imidazoline binding sites in positive and negative morphine analgesia modulatory effects.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Benzofurans; CHO Cells; Cricetinae; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Mice; Models, Molecular; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Radioligand Assay; Reaction Time; Receptors, Adrenergic, alpha-2; Receptors, Drug; Receptors, Opioid, mu; Yohimbine | 2006 |
Agmatine blocks morphine-evoked hyperthermia in rats.
Topics: Agmatine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Biogenic Amines; Body Temperature Regulation; Dose-Response Relationship, Drug; Drug Interactions; Fever; Idazoxan; Imidazoline Receptors; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Drug; Receptors, Opioid, mu; Yohimbine | 2007 |
Agmatine inhibits morphine-induced locomotion sensitization and morphine-induced changes in striatal dopamine and metabolites in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Agmatine; Analysis of Variance; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Dynorphins; Gene Expression Regulation; Homovanillic Acid; Idazoxan; Locomotion; Male; Morphine; Narcotics; Rats; Rats, Wistar; Time Factors | 2007 |
Low doses of alpha 2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Idazoxan; Imidazoles; Male; Mianserin; Mirtazapine; Morphine; Rats; Rats, Sprague-Dawley; Spine; Yohimbine | 2008 |
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2009 |
Effect of agmatine on long-term potentiation in morphine-treated rats.
Topics: Agmatine; Animals; Dentate Gyrus; Drug Interactions; Hippocampus; Idazoxan; Imidazoline Receptors; Long-Term Potentiation; Male; Morphine; Rats; Rats, Wistar | 2010 |
Agmatine inhibits morphine-induced memory impairment in the mouse step-down inhibitory avoidance task.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Idazoxan; Imidazoline Receptors; Male; Memory Disorders; Mental Recall; Mice; Morphine | 2010 |
Determination of α(2)-adrenoceptor and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by agmatine and BMS182874.
Topics: Agmatine; Analgesics; Animals; Dansyl Compounds; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Oxycodone; Receptors, Adrenergic, alpha-2; Receptors, Endothelin; Yohimbine | 2011 |
Study of adrenergic, imidazoline, and endothelin receptors in clonidine-, morphine-, and oxycodone-induced changes in rat body temperature.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Body Temperature; Body Temperature Regulation; Brain; Clonidine; Dansyl Compounds; Drug Synergism; Endothelin A Receptor Antagonists; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Yohimbine | 2011 |
Morphine-induced antinociception in the rat: supra-additive interactions with imidazoline I₂ receptor ligands.
Topics: Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Yohimbine | 2011 |
Assessment of the analgesic effect of centhaquin in mouse tail flick and hot-plate tests.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Antihypertensive Agents; Body Temperature; Drug Interactions; Endothelin A Receptor Antagonists; Hot Temperature; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain; Piperazines; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine | 2011 |
Involvement of α₂-adrenoceptors, imidazoline, and endothelin-A receptors in the effect of agmatine on morphine and oxycodone-induced hypothermia in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Agmatine; Animals; Body Temperature Regulation; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Hypothermia; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Oxycodone; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Yohimbine | 2013 |
Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Binding Sites; Drug Synergism; Female; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Quinazolines; Rats, Sprague-Dawley; Yohimbine | 2014 |