Page last updated: 2024-08-23

idazoxan and metoprolol

idazoxan has been researched along with metoprolol in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Branch, CA; Knuepfer, MM1
Bearham, MC; Heal, DJ; Hutchins, LJ; Jackson, HC; Mazurkiewicz, SE; Needham, AM1
CarĂ³n, RW; Deis, RP; Salicioni, AM1
Noma, T; Sugimoto, Y; Yamada, J1
Castrucci, AM; de Oliveira, AR; Scarparo, AC; Visconti, MA1

Other Studies

9 other study(ies) available for idazoxan and metoprolol

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Adrenergic mechanisms underlying cardiac and vascular responses to cocaine in conscious rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cocaine; Dioxanes; Drug Interactions; Heart Rate; Idazoxan; Male; Metoprolol; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation; Yohimbine

1992
Investigation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Animals; Cyclobutanes; Eating; Idazoxan; Male; Metoprolol; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors

1997
Participation of both adrenergic and opioidergic systems in the negative feedback of adrenal progesterone on LH secretion.
    European journal of pharmacology, 1997, Aug-13, Volume: 332, Issue:3

    Topics: Adrenal Glands; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Estradiol; Feedback; Female; Hormone Antagonists; Idazoxan; Luteinizing Hormone; Metoprolol; Mifepristone; Naloxone; Ovariectomy; Prazosin; Progesterone; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Opioid

1997
Involvement of adrenaline in diazepam-induced hyperglycemia in mice.
    Life sciences, 2000, Feb-18, Volume: 66, Issue:13

    Topics: Adrenergic beta-Antagonists; alpha-Methyltyrosine; Animals; Blood Glucose; Diazepam; Epinephrine; Hyperglycemia; Idazoxan; Insulin; Isoquinolines; Male; Metoprolol; Mice; Propanolamines

2000
Adrenoceptors in normal and malignant human melanocytes.
    Archives of dermatological research, 2000, Volume: 292, Issue:5

    Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Idazoxan; Melanocytes; Metoprolol; Oxathiins; Propanolamines; Propranolol; Receptors, Adrenergic; Tumor Cells, Cultured; Yohimbine

2000