idazoxan has been researched along with gamma-aminobutyric acid in 19 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Corbett, R; Dunn, RW | 1 |
| Hamahashi, T; Itoh, T; Kamisaki, Y; Okada, CM | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Simonato, M; Spalluto, P; Tanganelli, S; Tomasini, C | 1 |
| Aston-Jones, G; Ennis, M | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Rando, S; Simonato, M; Tanganelli, S | 1 |
| Cahusac, PM; Hill, RG | 1 |
| Goodwin, WB; Guyenet, PG; Huangfu, D | 1 |
| Allen, AM; Guyenet, PG | 1 |
| Acciarri, N; Antonelli, T; Beani, L; Bianchi, C; Caló, G; Fabrizi, A; Ferraro, L; Simonato, M; Tanganelli, S | 1 |
| Cools, AR; Koide, S; Koshikawa, N; Misaki, T; Murai, T; Takada, K; Yoshida, Y | 1 |
| Holmberg, M; Kurose, H; Miettinen, R; Scheinin, M | 1 |
| Bédard, PJ; Doan, VD; Grondin, R; Hadj Tahar, A; Ladure, P | 1 |
| Honda, M; Ono, H; Takasu, K; Tanabe, M | 1 |
| Freiman, TM; Heinemeyer, J; Klar, M; Kukolja, J; Surges, R; van Velthoven, V; Zentner, J | 1 |
| Curry, R; DeGoes, S; Eisenach, JC; Hayashida, K | 1 |
| Beitz, AJ; Han, HJ; Kim, HW; Kwon, YB; Lee, JH; Roh, DH; Seo, HS; Yoon, SY | 1 |
| Authier, N; Bertrand, M; Chapuy, E; Chenaf, C; Courteix, C; Eschalier, A; Gabriel, C; Libert, F; Marchand, F; Mocaër, E | 1 |
| Eisenach, JC; Hayashida, KI; Kimuram, M | 1 |
1 trial(s) available for idazoxan and gamma-aminobutyric acid
| Article | Year |
|---|---|
Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery.
Topics: Adrenergic alpha-Antagonists; Amines; Analgesics; Analgesics, Opioid; Animals; Bee Venoms; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Idazoxan; Male; Morphine; Norepinephrine; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerve Roots; Time Factors | 2007 |
18 other study(ies) available for idazoxan and gamma-aminobutyric acid
| Article | Year |
|---|---|
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Yohimbine-induced seizures involve NMDA and GABAergic transmission.
Topics: Animals; Bicuculline; Carbolines; Convulsants; Dioxanes; gamma-Aminobutyric Acid; Idazoxan; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Adrenergic, alpha; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Synaptic Transmission; Yohimbine | 1992 |
Clonidine inhibition of potassium-evoked release of glutamate and aspartate from rat cortical synaptosomes.
Topics: Analysis of Variance; Animals; Aspartic Acid; Cerebral Cortex; Clonidine; Dioxanes; gamma-Aminobutyric Acid; Glutamates; Idazoxan; Kinetics; Male; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1991 |
Changes in cortical acetylcholine and gamma-aminobutyric acid outflow during morphine withdrawal involve alpha-1 and alpha-2 receptors.
Topics: Acetylcholine; Animals; Clonidine; Dioxanes; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Naloxone; Prazosin; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome | 1989 |
GABA-mediated inhibition of locus coeruleus from the dorsomedial rostral medulla.
Topics: Animals; Bicuculline; Dioxanes; Evoked Potentials; gamma-Aminobutyric Acid; Idazoxan; Iontophoresis; Locus Coeruleus; Male; Medulla Oblongata; Naloxone; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains | 1989 |
Inversion of the alpha-2 and alpha-1 noradrenergic control of the cortical release of acetylcholine and gamma-aminobutyric acid in morphine-tolerant guinea pigs.
Topics: Acetylcholine; Animals; Cerebral Cortex; Clonidine; Dioxanes; Drug Tolerance; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha | 1988 |
Alpha-2 adrenergic receptors on neurones in the region of the lateral reticular nucleus of the rat.
Topics: Animals; Clonidine; Dioxins; Evoked Potentials; gamma-Aminobutyric Acid; Humans; Idazoxan; Medulla Oblongata; Neurons; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Reticular Formation; Synaptic Transmission | 1983 |
Sympatholytic effect of tricyclic antidepressants: site and mechanism of action in anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Baclofen; Blood Pressure; Brain Mapping; Desipramine; Dioxanes; Fluoxetine; gamma-Aminobutyric Acid; Idazoxan; Imidazoles; Male; Medulla Oblongata; Microinjections; Nordefrin; Oxidopamine; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Sympatholytics; Time Factors | 1995 |
Alpha 2-adrenoceptor-mediated inhibition of bulbospinal barosensitive cells of rat rostral medulla.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Evoked Potentials; gamma-Aminobutyric Acid; Idazoxan; Injections, Intravenous; Iontophoresis; Male; Medulla Oblongata; Neurons; Nordefrin; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 1993 |
Noradrenergic modulation of gamma-aminobutyric acid outflow from the human cerebral cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cerebral Cortex; Dioxanes; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Guinea Pigs; Humans; Idazoxan; In Vitro Techniques; Isoproterenol; Kinetics; Norepinephrine; Ouabain; Phenylephrine; Potassium; Prazosin; Rats; Species Specificity; Synaptosomes; Tetrodotoxin | 1993 |
Clonidine reduces dopamine and increases GABA in the nucleus accumbens: an in vivo microdialysis study.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dopamine; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Idazoxan; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1998 |
Adrenergic alpha2C-receptors reside in rat striatal GABAergic projection neurons: comparison of radioligand binding and immunohistochemistry.
Topics: Adrenergic alpha-Antagonists; Animals; Antibodies; Autoradiography; Binding, Competitive; Brain Chemistry; Calbindin 1; Calbindin 2; Calbindins; Corpus Striatum; gamma-Aminobutyric Acid; Idazoxan; Immunohistochemistry; Male; Neurons; Norepinephrine; Parvalbumins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; S100 Calcium Binding Protein G; Tissue Fixation; Tritium; Yohimbine | 1999 |
Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Idazoxan; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Norepinephrine; Parkinson Disease | 2000 |
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Narcotic Antagonists; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sciatic Nerve; Spinal Cord; Touch; Yohimbine | 2006 |
K(+)-evoked [(3)H]-norepinephrine release in human brain slices from epileptic and non-epileptic patients is differentially modulated by gabapentin and pinacidil.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Amines; Anticonvulsants; Brimonidine Tartrate; Calcium Channel Blockers; Child; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Idazoxan; In Vitro Techniques; Male; Middle Aged; Norepinephrine; omega-Conotoxins; Pinacidil; Potassium; Quinoxalines; Time Factors; Tritium | 2006 |
Intrathecal clonidine suppresses phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit in spinal dorsal horn neurons of rats with neuropathic pain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amines; Analgesics; Animals; Anticonvulsants; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gabapentin; gamma-Aminobutyric Acid; Idazoxan; Neuralgia; Phosphorylation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord | 2008 |
Agomelatine: a new opportunity to reduce neuropathic pain-preclinical evidence.
Topics: Acetamides; Adrenergic alpha-2 Receptor Antagonists; Amines; Animals; Antineoplastic Agents; Constriction, Pathologic; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Hypnotics and Sedatives; Idazoxan; Male; Motor Activity; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes | 2017 |
Blockade of α2-adrenergic or metabotropic glutamate receptors induces glutamate release in the locus coeruleus to activate descending inhibition in rats with chronic neuropathic hypersensitivity.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Idazoxan; Locus Coeruleus; Male; Neural Inhibition; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Metabotropic Glutamate; Spinal Nerves | 2018 |