idazoxan has been researched along with diazoxide in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chan, SL; Morgan, NG; Stillings, MR | 1 |
| Angel, I; Eon, MT; Langer, SZ; Lorrain, J; Oblin, A | 1 |
| Haque, M; Kulkarni, RN; MacDermot, J; Olmos, G | 1 |
| Angel, I; Henquin, JC; Jonas, JC; Langer, SZ; Plant, TD | 1 |
| Brown, CA; Morgan, NG | 1 |
| Berggren, PO; Efanov, AM; Efanova, IB; Efendić, S; Gold, G; Larsson, O; Ostenson, CG; Zaitsev, SV | 1 |
| Chan, SL; Morgan, NG; Scarpello, KE | 1 |
| Martín-Ruiz, R; Pineda, J; Ruiz-Ortega, JA; Ugedo, L | 1 |
12 other study(ies) available for idazoxan and diazoxide
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Mechanisms involved in stimulation of insulin secretion by the hypoglycaemic alpha-adrenergic antagonist, DG-5128.
Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Diazoxide; Dioxanes; Dose-Response Relationship, Drug; Hypoglycemic Agents; Idazoxan; Imidazoles; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Phentolamine; Rats; Rats, Inbred Strains | 1991 |
Inhibition of insulin release induced by galanin in the dog is not exclusively mediated by activation of ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Diazoxide; Dioxanes; Dogs; Female; Galanin; Ganglia, Sympathetic; Glyburide; Idazoxan; Insulin; Insulin Secretion; Male; Norepinephrine; Pancreas; Peptides; Potassium Channels; Quinoxalines; Receptors, Adrenergic, alpha; Sensitivity and Specificity | 1993 |
Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Affinity Labels; Animals; Benzofurans; Binding, Competitive; Clonidine; Clorgyline; Diazoxide; Dioxanes; Guanidines; Idazoxan; Imidazoles; Imidazoline Receptors; Insulin; Insulinoma; Ligands; Pancreatic Neoplasms; Potassium Channels; Rats; Receptors, Drug; Regression Analysis; Software; Tumor Cells, Cultured | 1994 |
In vitro stimulation of insulin release by SL 84.0418, a new alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Diazoxide; Dioxanes; Electrophysiology; Female; Glucose; Idazoxan; In Vitro Techniques; Indoles; Insulin; Islets of Langerhans; Mice; Potassium Channels; Pyrroles; Rubidium Radioisotopes; Tolbutamide | 1994 |
Control of insulin secretion by imidazolines in rat pancreatic islets.
Topics: Animals; Benzofurans; Diazoxide; Dioxanes; Idazoxan; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Rats | 1993 |
Imidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinery.
Topics: Animals; Brimonidine Tartrate; Calcium; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytosol; Diazoxide; Exocytosis; Glucose; Idazoxan; Imidazoles; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Potentials; Phentolamine; Potassium Channels; Potassium Chloride; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Tumor Cells, Cultured | 1996 |
Identification and characterization of non-adrenergic binding sites in insulin-secreting cells with the imidazoline RX821002.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Cell Line; Cell Membrane; Cells, Cultured; Diazoxide; Glucose; Idazoxan; Islets of Langerhans; Kinetics; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, Cell Surface | 1997 |
Stimulation of locus coeruleus neurons by non-I1/I2-type imidazoline receptors: an in vivo and in vitro electrophysiological study.
Topics: Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Diazoxide; Electrophysiology; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Ligands; Locus Coeruleus; Male; Neurons; Potassium Channels; Rats; Receptors, Adrenergic, alpha-2; Receptors, Drug; Vasodilator Agents | 1998 |