idazoxan has been researched along with cocaine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (27.27) | 18.7374 |
| 1990's | 13 (39.39) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Griffin, IJ; Jackson, HC; Nutt, DJ | 1 |
| Branch, CA; Knuepfer, MM | 1 |
| Harris, GC; Hausken, ZE; Williams, JT | 1 |
| Butcher, SP; Clark, AJ; Winn, P | 1 |
| Ball, DM; Jackson, HC; Nutt, DJ | 1 |
| Chen, DG; Chen, RX; Li, JM; Xu, B; Zhang, L | 1 |
| Hall, MT; Hamilton, CA; Kane, KA; Reid, JL; Rodger, IW; Wadsworth, RM | 1 |
| Heepe, P; Starke, K | 1 |
| Hicks, PE; Langer, SZ; Macrae, AD | 1 |
| McCulloch, MW; Papanicolaou, M; Rand, MJ | 1 |
| Folkow, B; Nilsson, H; Sjöblom, N | 1 |
| Medgett, IC; Papanicolaou, M | 1 |
| Langer, SZ; Medgett, IC | 1 |
| Doggrell, SA; Hughes, EW | 1 |
| Doxey, JC; Lane, AC; Roach, AG; Virdee, NK | 1 |
| Galzin, AM; Langer, SZ; Moret, C | 1 |
| Chen, NH; Reith, ME | 2 |
| Costentin, J; Dupuis, R; Simon, P | 1 |
| Abrahams, TP; Liu, W; Varner, KJ | 1 |
| Buchholz, JN; Duckles, SP; García-Villalón, AL; Krause, DN | 1 |
| Buchholz, J; Hewitt, CW; Sexton, P | 1 |
| Buchholz, J; Duckles, SP | 1 |
| Bayer, LE; Booze, RM; Kakumanu, S; Mactutus, CF; Strupp, BJ | 1 |
| Booze, RM; Mactutus, CF; Silvers, JM; Snow, DM; Strupp, BJ; Wallace, DR | 1 |
| Feliu-Mojer, M; Jiménez-Rivera, CA; Vázquez-Torres, R | 1 |
| Borgkvist, A; Feltmann, K; Lindskog, M; Malmlöf, T; Schilström, B | 1 |
| Achterberg, EJ; Schoffelmeer, AN; Schrama, L; Siviy, SM; Trezza, V; Vanderschuren, LJ | 1 |
| Beveridge, TJ; Nader, MA; Porrino, LJ; Smith, HR | 1 |
| Aalderink, M; Achterberg, EJ; Driel, NV; Houwing, DJ; Servadio, M; Trezza, V; van Kerkhof, LW; van Swieten, MM; Vanderschuren, LJ | 1 |
| Dobrzański, G; Kwiatkowska, K; Pradel, K; Przewłocki, R; Solecki, WB; Szklarczyk, K | 1 |
| Asaoka, Y; Kamii, H; Kaneda, K; Minami, M; Shinohara, F | 1 |
33 other study(ies) available for idazoxan and cocaine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Alpha 2-adrenoceptor antagonists block the stimulant effects of cocaine in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dioxanes; Idazoxan; Male; Mice; Motor Activity | 1992 |
Adrenergic mechanisms underlying cardiac and vascular responses to cocaine in conscious rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cocaine; Dioxanes; Drug Interactions; Heart Rate; Idazoxan; Male; Metoprolol; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation; Yohimbine | 1992 |
Cocaine induced synchronous oscillations in central noradrenergic neurons in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dioxanes; Evoked Potentials; Idazoxan; In Vitro Techniques; Kinetics; Kynurenic Acid; Locus Coeruleus; Male; Membrane Potentials; Neurons; Oscillometry; Picrotoxin; Prazosin; Rats; Rats, Wistar; Strychnine; Synapses | 1992 |
Evidence for functional separation of alpha-1 and alpha-2 noradrenaline receptors by pre-synaptic terminal re-uptake mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Chromatography, High Pressure Liquid; Cocaine; Dioxanes; Eating; Hydroxydopamines; Idazoxan; In Vitro Techniques; Male; Microinjections; Nerve Endings; Norepinephrine; Oxidopamine; Paraventricular Hypothalamic Nucleus; Phentolamine; Rats; Receptors, Adrenergic, alpha; Synapses | 1991 |
Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Desipramine; Dioxanes; Hyperkinesis; Idazoxan; Injections, Intraperitoneal; Mice; Norepinephrine; Seizures | 1990 |
[Modulation of norepinephrine release in sympathetic nerve endings in renal hypertensive dogs].
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dioxanes; Dogs; Female; Hypertension, Renal; Idazoxan; Male; Nerve Endings; Norepinephrine; Prazosin; Sympathetic Nervous System; Tyramine | 1990 |
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cocaine; Dioxanes; Hypertension, Renovascular; Idazoxan; Kidney; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Potassium Chloride; Prazosin; Rabbits; Time Factors | 1990 |
Alpha-adrenoceptor antagonists and the release of noradrenaline in rabbit cerebral cortex slices: support for the alpha-autoreceptor hypothesis.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Cocaine; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Rabbits; Secologanin Tryptamine Alkaloids; Tetraethylammonium Compounds | 1985 |
Differential blocking actions of idazoxan against the inhibitory effects of 6-fluoronoradrenaline and clonidine in the rat vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Dioxanes; Dioxins; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pargyline; Rats; Reserpine; Vas Deferens | 1985 |
Evidence for autoinhibition of stimulation-induced noradrenaline release from vasa deferentia of the guinea-pig and rat.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dioxanes; Electric Stimulation; Epididymis; Guinea Pigs; Hydrocortisone; Idazoxan; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Prostate; Rats; Species Specificity; Vas Deferens | 1985 |
Interaction between prejunctional alpha 2-receptors and neuronal transmitter reuptake in small mesenteric arteries from the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Cocaine; Dioxanes; Electric Stimulation; Hydroxydopamines; Idazoxan; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Denervation; Muscle, Smooth, Vascular; Neuromuscular Junction; Neurotransmitter Agents; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Vascular Resistance; Yohimbine | 1985 |
Effects of blockade of alpha 1- and alpha 2-adrenoceptors on vasoconstrictor responses to single and twin pulse stimulation in rat tail artery.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Cocaine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Prazosin; Rats; Rats, Inbred Strains; Regional Blood Flow; Tail; Vasoconstriction | 1986 |
Influence of neuronal uptake on the contribution of smooth muscle alpha 2-adrenoceptors to vasoconstrictor responses to noradrenaline in SHR and WKY isolated tail arteries.
Topics: Animals; Arteries; Cocaine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neurons; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Regional Blood Flow; Species Specificity; Tail; Vasoconstriction | 1986 |
Comparison of the effects of labetalol and SCH 19927, the R1R isomer of labetalol, on the rat isolated right ventricle and aorta.
Topics: Animals; Aorta; Cocaine; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Idazoxan; In Vitro Techniques; Isoproterenol; Labetalol; Male; Myocardial Contraction; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Vasoconstriction | 1985 |
Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cocaine; Decerebrate State; Dioxins; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine | 1984 |
Evidence that exogenous but not endogenous norepinephrine activates the presynaptic alpha-2 adrenoceptors on serotonergic nerve endings in the rat hypothalamus.
Topics: Animals; Cocaine; Desipramine; Dioxins; Hypothalamus; Idazoxan; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Yohimbine | 1984 |
Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Biogenic Monoamines; Cocaine; Dioxanes; Idazoxan; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sulpiride; Tegmentum Mesencephali | 1995 |
Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Arousal; Cocaine; Dextroamphetamine; Dioxanes; Dopamine; Dopamine Agents; Exploratory Behavior; Idazoxan; Mice; Motor Activity; Orientation; Pentylenetetrazole; Proprioception; Receptors, Dopamine; Synaptic Transmission; Yohimbine | 1994 |
Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats.
Topics: Animals; Biogenic Monoamines; Cocaine; Dioxanes; Dopamine; Homeostasis; Idazoxan; Methiothepin; Microdialysis; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sulpiride; Ventral Tegmental Area | 1994 |
Blockade of alpha-2 adrenergic receptors in the rostral ventrolateral medulla attenuates the sympathoinhibitory response to cocaine.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blood Pressure; Cocaine; Idazoxan; Male; Medulla Oblongata; Microinjections; Piperoxan; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sympatholytics | 1996 |
Noradrenaline content and release in male and female rat tail arteries.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Cocaine; Desoxycorticosterone; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Orchiectomy; Ovariectomy; Rats; Rats, Inbred F344; Sex Factors; Tail | 1997 |
Impact of age on modulation of norepinephrine release from sympathetic nerves in the rat superior mesentery artery.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Fibers; Aging; Animals; Cocaine; Desoxycorticosterone; Electric Stimulation; Idazoxan; Male; Mesenteric Artery, Superior; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents | 1998 |
Chronic hypoxia alters prejunctional alpha(2)-receptor function in vascular adrenergic nerves of adult and fetal sheep.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Arteries; Chronic Disease; Cocaine; Desoxycorticosterone; Face; Female; Fetal Hypoxia; Idazoxan; In Vitro Techniques; Middle Cerebral Artery; Norepinephrine; Perfusion; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Adrenergic, alpha-2; Sheep; Sympathetic Nervous System | 2001 |
Prenatal cocaine exposure alters sensitivity to the effects of idazoxan in a distraction task.
Topics: Adrenergic alpha-Antagonists; Animals; Attention; Cocaine; Female; Idazoxan; Injections, Intravenous; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Rats; Rats, Long-Evans | 2002 |
Prenatal cocaine exposure alters alpha2 receptor expression in adolescent rats.
Topics: Adrenergic alpha-Antagonists; Age Factors; Animals; Autoradiography; Body Weight; Cocaine; Dopamine Uptake Inhibitors; Female; Idazoxan; Male; Pregnancy; Prenatal Exposure Delayed Effects; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sexual Maturation; Tritium | 2006 |
Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Cocaine; Idazoxan; Male; Motor Activity; Prazosin; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine | 2006 |
Dopamine in the hippocampus is cleared by the norepinephrine transporter.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Interactions; Hippocampus; Idazoxan; Male; Microdialysis; Morpholines; Nomifensine; Norepinephrine Plasma Membrane Transport Proteins; Raclopride; Rats; Rats, Wistar; Reboxetine; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Wakefulness | 2012 |
Amphetamine and cocaine suppress social play behavior in rats through distinct mechanisms.
Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Atomoxetine Hydrochloride; Behavior, Animal; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; Flupenthixol; Idazoxan; Male; Motor Activity; Piperazines; Play and Playthings; Propylamines; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Social Behavior | 2014 |
Effects of abstinence from chronic cocaine self-administration on nonhuman primate dorsal and ventral noradrenergic bundle terminal field structures.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Autoradiography; Brain; Cocaine; Cocaine-Related Disorders; Fluoxetine; Idazoxan; Macaca mulatta; Male; Neural Pathways; Norepinephrine Plasma Membrane Transport Proteins; Receptors, Adrenergic, alpha-2; Reinforcement Schedule; Self Administration | 2016 |
Contrasting Roles of Dopamine and Noradrenaline in the Motivational Properties of Social Play Behavior in Rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Cocaine; Conditioning, Operant; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Flupenthixol; Idazoxan; Male; Methylphenidate; Motivation; Neuropsychological Tests; Norepinephrine; Piperazines; Random Allocation; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Dopamine; Social Behavior | 2016 |
Noradrenergic signaling in the VTA modulates cocaine craving.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Craving; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Idazoxan; Male; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Self Administration; Ventral Tegmental Area | 2018 |
Stress augments the rewarding memory of cocaine via the activation of brainstem-reward circuitry.
Topics: Adrenergic alpha-Antagonists; Adrenergic Neurons; Animals; Brain Stem; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Idazoxan; Male; Memory; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Restraint, Physical; Reward; Stress, Psychological; Tegmentum Mesencephali; Timolol | 2019 |