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idazoxan and 8-hydroxy-2-(di-n-propylamino)tetralin

idazoxan has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.79)18.7374
1990's18 (62.07)18.2507
2000's5 (17.24)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jackson, HC; Nutt, DJ1
Guyenet, PG; Nosjean, A1
Bloetjes, K; Mos, J; Olivier, B; Van Logten, J1
Crespi, F; Garratt, JC; Marsden, CA; Mason, R1
Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M1
Marsden, CA; Martin, KF1
Berthold, H; Engel, G; Fozard, JR1
Davidson, JM; Kwong, LL; Peroutka, SJ; Smith, ER1
Fozard, JR; Ramage, AG1
Cervo, L; Rossi, C; Samanin, R; Tatarczynska, E1
Chen, NH; Reith, ME1
Coscina, DV; Currie, PJ1
Baba, A; Kawai, N; Moroji, T; Yamamoto, H; Yamamoto, T1
Gidener, S; LePard, KJ; Stephens, RL1
de Boer, TH; Nefkens, F; van Delft, AM; van Helvoirt, A1
Clark, R; McRae, G; Spedding, M; Tallentire, D; Vickery, B1
Leander, JD; Wolff, MC1
Grupp, LA; Harding, S; Lau, V1
Audinot, V; Cistarelli, L; Gobert, A; Millan, MJ; Newman-Tancredi, A; Rivet, JM1
Clarke, RW; Ogilvie, J1
Aguerre, S; Chaouloff, F; Mormede, P1
Giroux, N; Reader, TA; Rossignol, S1
Bouvard, M; Rénéric, JP; Stinus, L1
Blier, P; Szabo, ST2
Grandoso, L; Pineda, J; Torrecilla, M; Ugedo, L1
Berrocoso, E; Mico, JA1
Anselmo-Franci, JA; Bícego, KC; de Souza Moreno, V; Gargaglioni, LH; Szawka, RE1
Bornstein, JC; Foong, JP; Gwynne, RM; Parry, LJ1

Other Studies

29 other study(ies) available for idazoxan and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
Are 5-HT receptors or beta-adrenoceptors involved in idazoxan-induced food and water intake?
    Neuropharmacology, 1992, Volume: 31, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Dioxanes; Dose-Response Relationship, Drug; Drinking; Eating; Idazoxan; Male; Metergoline; Propanolamines; Propranolol; Quinolizines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin; Stereoisomerism

1992
Role of ventrolateral medulla in sympatholytic effect of 8-OHDPAT in rats.
    The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; Lumbosacral Region; Male; Medulla Oblongata; Neurons; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System; Sympatholytics; Tetrahydronaphthalenes; Yohimbine

1991
The effects of idazoxan and 8-OH-DPAT on sexual behaviour and associated ultrasonic vocalizations in the rat.
    Neuroscience and biobehavioral reviews, 1991,Winter, Volume: 15, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Dioxanes; Ejaculation; Female; Idazoxan; Male; Rats; Rats, Inbred Strains; Refractory Period, Psychological; Sexual Behavior, Animal; Tetrahydronaphthalenes; Ultrasonics; Vocalization, Animal

1991
Effects of idazoxan on dorsal raphe 5-hydroxytryptamine neuronal function.
    European journal of pharmacology, 1991, Jan-25, Volume: 193, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Anesthesia; Animals; Dioxanes; Electrophysiology; Hydroxyindoleacetic Acid; Idazoxan; In Vitro Techniques; Injections, Intraventricular; Iontophoresis; Male; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1991
Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Cattle; Cerebral Cortex; Dioxanes; Hippocampus; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Tetrahydronaphthalenes; Yohimbine

1990
Involvement of 5-HT1A- and alpha 2-receptors in the decreased 5-hydroxytryptamine release and metabolism in rat suprachiasmatic nucleus after intravenous 8-hydroxy-2-(n-dipropylamino) tetralin.
    British journal of pharmacology, 1986, Volume: 89, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Dioxanes; Hydroxyindoleacetic Acid; Idazoxan; Male; Methiothepin; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Suprachiasmatic Nucleus; Tetrahydronaphthalenes

1986
5-HT1 receptor agonists attenuate the naloxone-induced jumping behaviour in morphine-dependent mice.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Buspirone; Dioxanes; Female; Fenclonine; Idazoxan; Indoles; Mice; Morphine Dependence; Naloxone; Prazosin; Receptors, Serotonin; Tetrahydronaphthalenes

1989
Differential interactions of "prosexual" drugs with 5-hydroxytryptamine1A and alpha 2-adrenergic receptors.
    Behavioral neuroscience, 1986, Volume: 100, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Brain; Dioxanes; Ejaculation; Idazoxan; Imidazoles; Indans; Male; Methoxydimethyltryptamines; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Stimulation, Chemical; Tetrahydronaphthalenes; Yohimbine

1986
Evidence that the putative 5-HT1A receptor agonists, 8-OH-DPAT and ipsapirone, have a central hypotensive action that differs from that of clonidine in anaesthetised cats.
    European journal of pharmacology, 1987, Jun-19, Volume: 138, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Cats; Clonidine; Dioxanes; Heart Rate; Idazoxan; Male; Naphthalenes; Neurons; Pyrimidines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes; Trimethaphan; Vagotomy

1987
Role of 5-HT1A receptors in the antinociceptive action of 8-hydroxy-2-(di-n- propylamino)tetralin in the rat.
    European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Idazoxan; Injections, Intraventricular; Injections, Subcutaneous; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists

1994
Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin.
    Journal of neurochemistry, 1995, Volume: 64, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Biogenic Monoamines; Cocaine; Dioxanes; Idazoxan; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sulpiride; Tegmentum Mesencephali

1995
Paraventricular nucleus injections of idazoxan block feeding induced by paraventricular nucleus norepinephrine but not intra-raphe 8-hydroxy-2-(di-n-propylamino)tetralin.
    Brain research, 1993, Nov-05, Volume: 627, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Dioxanes; Feeding Behavior; Idazoxan; Injections; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Raphe Nuclei; Rats; Rats, Sprague-Dawley

1993
Inhibitory effect of idazoxan on forskolin-stimulated adenylate cyclase activity through 5-hydroxytryptamine1A receptors.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Colforsin; Dioxanes; Hippocampus; Idazoxan; In Vitro Techniques; Male; Membranes; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin

1994
8-OH-DPAT stimulates gastric acid secretion through a vagal-independent, adrenal-mediated mechanism.
    European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Glands; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine Antagonists; Ganglia, Sympathetic; Gastric Acid; Gastric Acidity Determination; Idazoxan; Imidazoles; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Spiperone; Splenic Artery; Stimulation, Chemical; Vagotomy; Vagus Nerve

1995
Differences in modulation of noradrenergic and serotonergic transmission by the alpha-2 adrenoceptor antagonists, mirtazapine, mianserin and idazoxan.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Corpus Striatum; Dioxanes; Hippocampus; Idazoxan; Imidazoles; Male; Mianserin; Mirtazapine; Norepinephrine; Prazosin; Rats; Rats, Wistar; Serotonin; Tetrodotoxin

1996
Modulation of sexual behaviour in the rat by a potent and selective alpha 2-adrenoceptor antagonist, delequamine (RS-15385-197).
    British journal of pharmacology, 1996, Volume: 118, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Female; Idazoxan; Imidazoles; Isoquinolines; Male; Naphthyridines; Orchiectomy; Ovariectomy; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Sexual Behavior, Animal; Stimulation, Chemical

1996
Differentiation of 5-HT1A receptor ligands by drug discrimination.
    European journal of pharmacology, 1997, Aug-27, Volume: 333, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aminopyridines; Animals; Behavior, Animal; Buspirone; Columbidae; Cyclohexylamines; Discrimination Learning; Dose-Response Relationship, Drug; Idazoxan; Ligands; Male; Pindolol; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists

1997
The reduction in alcohol intake by the 5-HT1A agonist 8-OH DPAT and its attenuation by the alpha 2 adrenergic antagonist idazoxan correlates with blood glucose levels.
    Psychopharmacology, 1997, Volume: 133, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Ethanol; Feeding Behavior; Idazoxan; Male; Rats; Rats, Wistar; Serotonin Receptor Agonists

1997
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.
    Neuroscience, 1998, Volume: 84, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Dopamine; Dopamine Agonists; Frontal Lobe; Guanabenz; Guinea Pigs; Homeostasis; Idazoxan; Imidazoles; Indoles; Isoindoles; Male; Medetomidine; Models, Neurological; Motor Activity; Norepinephrine; Oxadiazoles; Piperazines; Prazosin; Raclopride; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Salicylamides; Serotonin

1998
Effect of RX 821002 at 5-HT1A-receptors in rabbit spinal cord in vivo.
    British journal of pharmacology, 1998, Volume: 123, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Female; Idazoxan; Male; Piperazines; Pyridines; Rabbits; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Spinal Cord

1998
GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats.
    Neuropharmacology, 1998, Volume: 37, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Hippocampus; Idazoxan; Ketanserin; Male; Mesencephalon; Mianserin; Nerve Endings; Oxadiazoles; Piperazines; Rats; Rats, Inbred WKY; Rats, Wistar; Reserpine; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Tryptophan Hydroxylase

1998
Autoradiographic study of alpha1- and alpha2-noradrenergic and serotonin1A receptors in the spinal cord of normal and chronically transected cats.
    The Journal of comparative neurology, 1999, Apr-12, Volume: 406, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Autoradiography; Cats; Denervation; Idazoxan; Isomerism; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reference Values; Serotonin Receptor Agonists; Spinal Cord

1999
Idazoxan and 8-OH-DPAT modify the behavioral effects induced by either NA, or 5-HT, or dual NA/5-HT reuptake inhibition in the rat forced swimming test.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Cyclopropanes; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Idazoxan; Male; Milnacipran; Motor Activity; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

2001
Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons.
    Brain research, 2001, Dec-13, Volume: 922, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Electric Stimulation; Electrophysiology; Fluorobenzenes; Idazoxan; Locus Coeruleus; Male; Neurons; Norepinephrine; Paroxetine; Patch-Clamp Techniques; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

2001
Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Clonidine; Electrophysiology; Idazoxan; Male; Morpholines; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists

2002
alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons.
    European journal of pharmacology, 2005, Jul-04, Volume: 517, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Idazoxan; In Vitro Techniques; Locus Coeruleus; Male; Methiothepin; Naloxone; Narcotic Antagonists; Neurons; Norepinephrine; Oxazines; Piperazines; Piperidines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

2005
In vivo effect of venlafaxine on locus coeruleus neurons: role of opioid, alpha(2)-adrenergic, and 5-hydroxytryptamine(1A) receptors.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Cyclohexanols; Idazoxan; Locus Coeruleus; Male; Naloxone; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Serotonin; Venlafaxine Hydrochloride

2007
Serotonergic mechanisms on breathing modulation in the rat locus coeruleus.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 459, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Amphetamines; Animals; Hydroxyindoleacetic Acid; Hypercapnia; Idazoxan; Ketanserin; Locus Coeruleus; Male; Microinjections; Piperazines; Pulmonary Ventilation; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Respiration; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2010
5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Gene Expression; Guinea Pigs; Idazoxan; Ileum; Inhibitory Postsynaptic Potentials; Lysine; Male; Myenteric Plexus; Neurons; Norepinephrine; Oligopeptides; Piperazines; Quinolines; Receptor, Serotonin, 5-HT1A; Receptors, Somatostatin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Receptor Agonists; Somatostatin; Submucous Plexus; Vasoactive Intestinal Peptide

2010