icrf 198 has been researched along with hydroxyl radical in 3 studies
Studies (icrf 198) | Trials (icrf 198) | Recent Studies (post-2010) (icrf 198) | Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) |
---|---|---|---|---|---|
24 | 0 | 4 | 10,147 | 26 | 3,657 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hasinoff, BB | 1 |
Hasinoff, BB; Malisza, KL | 1 |
Thomas, C; Vile, GF; Winterbourn, CC | 1 |
3 other study(ies) available for icrf 198 and hydroxyl radical
Article | Year |
---|---|
NADPH-cytochrome-P450 reductase promotes hydroxyl radical production by the iron complex of ADR-925, the hydrolysis product of ICRF-187 (dexrazoxane).
Topics: Animals; Catalase; Chelating Agents; Edetic Acid; Electron Spin Resonance Spectroscopy; Ethylenediamines; Glycine; Hydroxyl Radical; Iron Chelating Agents; Models, Chemical; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Razoxane; Spectrophotometry, Ultraviolet | 1995 |
Doxorubicin reduces the iron(III) complexes of the hydrolysis products of the antioxidant cardioprotective agent dexrazoxane (ICRF-187) and produces hydroxyl radicals.
Topics: Aerobiosis; Antibiotics, Antineoplastic; Antioxidants; Chelating Agents; Doxorubicin; Electron Spin Resonance Spectroscopy; Ethylenediamines; Ferric Compounds; Ferrous Compounds; Glycine; Heart; Hydrolysis; Hydroxyl Radical; Mitoxantrone; Models, Chemical; Oxidation-Reduction; Razoxane | 1995 |
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction.
Topics: Ascorbic Acid; Chelating Agents; Deoxyribose; Dimethyl Sulfoxide; Doxorubicin; Edetic Acid; Ethylenediamines; Ferric Compounds; Glycine; Hydrogen Peroxide; Hydrolysis; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Oxidation-Reduction; Paraquat; Razoxane; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1993 |