iclaprim and linezolid
iclaprim has been researched along with linezolid in 6 studies
Compound Research Comparison
| Studies (iclaprim) | Trials (iclaprim) | Recent Studies (post-2010) (iclaprim) | Studies (linezolid) | Trials (linezolid) | Recent Studies (post-2010) (linezolid) |
|---|---|---|---|---|---|
| 45 | 7 | 16 | 3,916 | 222 | 2,188 |
Protein Interaction Comparison
| Protein | Taxonomy | iclaprim (IC50) | linezolid (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 8.19 | |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | 2.1 | |
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | Homo sapiens (human) | 8.19 |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hawser, S; Islam, K; Schneider, P | 1 |
| Fritsche, TR; Jones, RN; Sader, HS | 1 |
| Hawser, S; Islam, K; Laue, H; Lociuro, S; Seguin, A; Valensise, T | 1 |
| Barrow, EW; Barrow, WW; Berlin, KD; Bourne, CR; Bourne, PC; Bunce, RA | 1 |
| Corey, GR; Stryjewski, ME | 1 |
| Cattoir, V; Daurel, C | 1 |
Reviews
2 review(s) available for iclaprim and linezolid
| Article | Year |
|---|---|
New treatments for methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Clinical Trials as Topic; Daptomycin; Evidence-Based Medicine; Glycopeptides; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Minocycline; Oxazolidinones; Pyrimidines; Streptococcal Infections; Tigecycline | 2009 |
[Update on antimicrobial chemotherapy].
Topics: Acetamides; Aminoglycosides; Anti-Infective Agents; beta-Lactams; Carbapenems; Cephalosporins; Daptomycin; Doripenem; Drug Resistance, Bacterial; Ertapenem; Fluoroquinolones; France; Humans; Linezolid; Lipoglycopeptides; Minocycline; Oxazolidinones; Penicillins; Pyrimidines; Teicoplanin; Tigecycline | 2010 |
Other Studies
4 other study(ies) available for iclaprim and linezolid
| Article | Year |
|---|---|
Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria.
Topics: Animals; Drug Resistance, Bacterial; Folic Acid Antagonists; Lung; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Pyrimidines; Sepsis; Staphylococcus aureus; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Trimethoprim Resistance; Vancomycin | 2003 |
Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates.
Topics: Anti-Bacterial Agents; Enterococcus faecalis; Europe; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Hospitalization; Humans; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrimidines; Staphylococcus aureus; Streptococcus; United States | 2009 |
In vitro bactericidal activity of iclaprim in human plasma.
Topics: Anti-Bacterial Agents; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Plasma; Pyrimidines; Staphylococcus aureus | 2009 |
Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1.
Topics: Anti-Bacterial Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Protein Structure, Secondary; Protein Structure, Tertiary; Staphylococcus aureus; Tetrahydrofolate Dehydrogenase | 2010 |