ici d2138 has been researched along with mk 0591 in 1 studies
Studies (ici d2138) | Trials (ici d2138) | Recent Studies (post-2010) (ici d2138) | Studies (mk 0591) | Trials (mk 0591) | Recent Studies (post-2010) (mk 0591) |
---|---|---|---|---|---|
23 | 2 | 0 | 64 | 6 | 17 |
Protein | Taxonomy | ici d2138 (IC50) | mk 0591 (IC50) |
---|---|---|---|
Cytochrome P450 3A4 | Homo sapiens (human) | 2.6029 | |
Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 4.0003 | |
Cytochrome P450 2D6 | Homo sapiens (human) | 0.011 | |
Cytochrome P450 2C9 | Homo sapiens (human) | 0.2503 | |
Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | 0.0086 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brideau, C; Chan, CC; Chauret, N; Delorme, D; Desmarais, S; Dubé, D; Ducharme, Y; Falgueyret, JP; Fortin, R; Girard, Y; Guay, J; Hamel, P; Jones, TR; Lépine, C; Li, C; McAuliffe, M; McFarlane, CS; Nicoll-Griffith, DA; Riendeau, D; Yergey, JA | 1 |
1 other study(ies) available for ici d2138 and mk 0591
Article | Year |
---|---|
Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Benzofurans; Bronchoconstriction; Drug Stability; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Microsomes, Liver; Molecular Structure; Naphthalenes; Neutrophils; Nitriles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Saimiri; Structure-Activity Relationship | 1996 |