Compounds > ici d2138
Page last updated: 2024-09-03

ici d2138 and indomethacin

ici d2138 has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(ici d2138)		Trials
(ici d2138)		Recent Studies (post-2010)
(ici d2138)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
232029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyici d2138 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bridoux, A; Henichart, JP; Millet, R; Pommery, J; Pommery, N1
Currie, JL; Isakson, PC; Kim, S; Rao, T; Shaffer, AF; Smith, WG; Thompson, JM1
Payne, AN; Price, RC; Yeadon, M1

Other Studies

3 other study(ies) available for ici d2138 and indomethacin

ArticleYear
Synthesis and biological activity of N-aroyl-tetrahydro-gamma-carbolines.
    Bioorganic & medicinal chemistry, 2010, Jun-01, Volume: 18, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbolines; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Humans; Indomethacin; Lipoxygenase Inhibitors; Male; Prostatic Neoplasms; Structure-Activity Relationship

2010
Characterization of 5-lipoxygenase inhibitors in biochemical and functional in vivo assays.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:3

    Topics: Animals; Antigens; Blood Vessels; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcimycin; Guinea Pigs; Humans; Hydroxyurea; Indomethacin; Lipoxygenase Inhibitors; Male; Pyrans; Quinolones; Rats; Skin

1995
Allergen-induced glycoconjugate secretion in guinea-pig trachea in vivo: modulation by indomethacin, BW B70C and ZD-2138.
    Pulmonary pharmacology, 1995, Volume: 8, Issue:1

    Topics: Acetylcholine; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Glycoconjugates; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Hydroxylamines; Hydroxyurea; Indomethacin; Lipoxygenase Inhibitors; Male; Methylurea Compounds; Pyrans; Quinolones; Spectrometry, Fluorescence; Trachea

1995