Page last updated: 2024-09-03

ici 89406 and pindolol

ici 89406 has been researched along with pindolol in 22 studies

Compound Research Comparison

Studies (ici 89406)	Trials (ici 89406)	Recent Studies (post-2010) (ici 89406)	Studies (pindolol)	Trials (pindolol)	Recent Studies (post-2010) (pindolol)
45	1	2	3,718	662	92

Protein Interaction Comparison

Protein	Taxonomy	pindolol (IC50)
Beta-2 adrenergic receptor	Homo sapiens (human)	0.0005
Beta-1 adrenergic receptor	Homo sapiens (human)	0.0009
Beta-3 adrenergic receptor	Homo sapiens (human)	0.088
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.048
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	0.048

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (50.00)	18.7374
1990's	11 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hartling, O; Svendsen, TL; Trap-Jensen, J	1
Fraeyman, N; Van de Velde, E; Van Ermen, A; Vanscheeuwijck, P	1
Boer, GJ; Erdtsieck-Ernste, BH; Feenstra, MG	1
Bast, A; Beusenberg, FD; Leurs, R; Timmerman, H; Van Amsterdam, JG	1
Ahmad, S; Chrétien, P; Daniel, EE; Shen, SH	1
Felder, CC; Jose, PA; McKelvey, AM; Nakamura, KT; Piccio, MM; Robillard, JE	1
Boehm, C; Houck, WT; Roberts, J; Tumer, N	1
Earley, KJ; Tenner, TE; Young, JA	1
Earley, KJ; Tenner, TE; Yen, YC; Young, JA	1
Booze, RM; Crisostomo, EA; Davis, JN	1
Artymyshyn, RP; Battisti, WP; Murray, M	1
Freissmuth, M; Nanoff, C; Schütz, W	1
Frame, LH; Liang, BT; Molinoff, PB	1
Palacios, JM; Pazos, A; Probst, A	1
Gerber, JG; Hedberg, A; Molinoff, PB; Nies, AS; Wolfe, BB	1
Frazer, A; O'Donnell, JM; Ordway, GA	1
Gabe, IT; Kimber, H; Mills, CJ; Sweeting, TJ; Thomas, M	1
Aller, MI; Candelas, MA; Fernández-López, A; Pazos, A; Revilla, V; Soria, C	1
Chiyotani, A; Konno, K; Takeuchi, S; Tamaoki, J; Yamauchi, F; Yamawaki, I	1
Duncan, GE; Kirkman, JA; Little, KY	1
Feller, DR; Konkar, AA; Lezama, EJ; Miller, DD; Salazar-Bookaman, MM	1
Butterworth, RF; Buu, PN; Michalak, A; Rose, C	1

Trials

1 trial(s) available for ici 89406 and pindolol

Article	Year
Effects of pindolol and propranolol on beta adrenergic receptors on human lymphocytes. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1 Topics: Animals; Cell Membrane; Double-Blind Method; Heart; Humans; Kinetics; Lung; Lymphocytes; Pindolol; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta	1986

Other Studies

21 other study(ies) available for ici 89406 and pindolol

Article	Year
Immediate haemodynamic effects of propranolol, practolol, pindolol, atenolol and ICI 89,406 in healthy volunteers. European journal of clinical pharmacology, 1979, May-21, Volume: 15, Issue:4 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Male; Pindolol; Practolol; Propanolamines; Propranolol	1979
Influence of age on the beta 1- and beta 2-adrenergic receptors in rat liver. Molecular pharmacology, 1992, Volume: 42, Issue:4 Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Membrane; Imidazoles; Liver; Liver Glycogen; Male; Pindolol; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta	1992
Pre- and postnatal developmental changes of adrenoceptor subtypes in rat brain. Journal of neurochemistry, 1991, Volume: 57, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Brain; Female; Iodine Radioisotopes; Iodocyanopindolol; Pindolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin	1991
Identification of beta 2-adrenoceptors on guinea pig alveolar macrophages using (-)-3-[125I]iodocyanopindolol. Inflammation, 1990, Volume: 14, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Membrane; Guinea Pigs; Iodine Radioisotopes; Iodocyanopindolol; Macrophages; Male; Pindolol; Propanolamines; Pulmonary Alveoli; Receptors, Adrenergic, beta; Timolol	1990
Characterization of beta adrenoceptors on cultured endothelial cells by radioligand binding. Life sciences, 1990, Volume: 47, Issue:25 Topics: Adrenergic alpha-Antagonists; Albuterol; Animals; Binding, Competitive; Cattle; Cells, Cultured; Endothelium, Vascular; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Pindolol; Propanolamines; Propranolol; Pulmonary Artery; Receptors, Adrenergic, beta	1990
Ontogeny of renal beta adrenoceptors in the sheep. Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:6 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Ethanolamines; Isoproterenol; Kidney; Pindolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Sheep; Vasodilation	1990
Cardiac beta-adrenoceptor binding characteristics with age following adrenal demedullation. British journal of pharmacology, 1990, Volume: 99, Issue:1 Topics: Adrenal Medulla; Aging; Animals; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Myocardium; Pindolol; Propanolamines; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta	1990
Characterization of beta-adrenoceptor subtypes in rabbit mononuclear leukocytes. European journal of pharmacology, 1989, Jan-31, Volume: 160, Issue:2 Topics: Animals; Binding, Competitive; In Vitro Techniques; Iodocyanopindolol; Leukocytes, Mononuclear; Male; Myocardium; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta	1989
Functional characterization of beta-adrenoceptor subtypes in rabbit right atria. Life sciences, 1989, Volume: 44, Issue:10 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atrial Function; Binding, Competitive; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Iodocyanopindolol; Isoproterenol; Myocardial Contraction; Norepinephrine; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Stimulation, Chemical; Terbutaline	1989
Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Brain; Guinea Pigs; Iodine Radioisotopes; Male; Pindolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Species Specificity	1989
Beta 1- and beta 2-adrenergic 125I-pindolol binding sites in the interpeduncular nucleus of the rat: normal distribution and the effects of deafferentation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:7 Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Denervation; Female; Iodine Radioisotopes; Locus Coeruleus; Mesencephalon; Pindolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values; Thalamus; Tissue Distribution	1989
The role of a low beta 1-adrenoceptor selectivity of [3H]CGP-12177 for resolving subtype-selectivity of competitive ligands. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:5 Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Iodocyanopindolol; Microsomes; Pindolol; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, beta	1987
Beta 2-adrenergic receptors contribute to catecholamine-stimulated shortening of action potential duration in dog atrial muscle. Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:13 Topics: Action Potentials; Animals; Atropine; Catecholamines; Dogs; Dose-Response Relationship, Drug; Heart Atria; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Reserpine	1985
Beta-adrenoceptor subtypes in the human brain: autoradiographic localization. Brain research, 1985, Dec-09, Volume: 358, Issue:1-2 Topics: Aged; Autoradiography; Binding, Competitive; Brain; Female; Humans; Iodocyanopindolol; Male; Middle Aged; Pindolol; Propanolamines; Receptors, Adrenergic, beta	1985
Effects of clenbuterol on central beta-1 and beta-2 adrenergic receptors of the rat. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: Animals; Cerebellum; Cerebral Cortex; Clenbuterol; Cyclic AMP; Ethanolamines; Isoproterenol; Pindolol; Propanolamines; Rats; Receptors, Adrenergic, beta	1987
Does beta-blockade directly reduce myocardial oxygen consumption? Cardiovascular research, 1981, Volume: 15, Issue:5 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Blood Pressure; Dogs; Heart; Heart Rate; Myocardium; Nitroprusside; Oxygen Consumption; Pindolol; Propanolamines	1981
Identification of beta-adrenoceptors in rat lymph nodes and spleen: an autoradiographic study. European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Binding Sites; Image Processing, Computer-Assisted; Ligands; Lymph Nodes; Male; Pindolol; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Serotonin; Spleen	1994
Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle. Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:1 Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; Cyclic AMP; Dogs; Ethanolamines; Female; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phentolamine; Pindolol; Propanolamines; Receptors, Adrenergic, beta	1993
Beta-adrenergic receptor subtypes in human pineal gland. Journal of pineal research, 1996, Volume: 20, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Autoradiography; Binding Sites; Female; Humans; Male; Middle Aged; Pindolol; Pineal Gland; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2	1996
Pharmacological study of atypical beta-adrenoceptors in rat esophageal smooth muscle. European journal of pharmacology, 1996, Jul-11, Volume: 308, Issue:1 Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Carbachol; Clenbuterol; Cyclohexane Monoterpenes; Esophagus; Ethanolamines; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Phenoxyacetates; Phenoxypropanolamines; Pindolol; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Serotonin Antagonists; Trachea; Tretoquinol	1996
Evidence for altered central noradrenergic function in experimental acute liver failure in the rat. Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebral Cortex; Chromatography, High Pressure Liquid; Coma; Dopamine; Frontal Lobe; Hippocampus; Hypothalamus; Idazoxan; Liver Failure, Acute; Microdialysis; Norepinephrine; Pindolol; Prazosin; Propanolamines; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Serotonin; Thalamus	1998