Page last updated: 2024-09-03

ici 89406 and ici 118551

ici 89406 has been researched along with ici 118551 in 29 studies

Compound Research Comparison

Studies (ici 89406)	Trials (ici 89406)	Recent Studies (post-2010) (ici 89406)	Studies (ici 118551)	Trials (ici 118551)	Recent Studies (post-2010) (ici 118551)
45	1	2	19	0	10
45	1	2	836	31	106

Protein Interaction Comparison

Protein	Taxonomy	ici 89406 (IC50)	ici 118551 (IC50)
Beta-2 adrenergic receptor	Homo sapiens (human)		0.0017
Alpha-2A adrenergic receptor	Homo sapiens (human)		0.0005

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (37.93)	18.7374
1990's	17 (58.62)	18.2507
2000's	1 (3.45)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baker, JG	1
Fraeyman, N; Van de Velde, E; Van Ermen, A; Vanscheeuwijck, P	1
Gousse, A; Latifpour, J; Weiss, RM; Yoshida, M	1
Singer, EA; Valenta, B	1
Goshima, Y; Misu, Y; Nakamura, S	1
Bast, A; Beusenberg, FD; Leurs, R; Timmerman, H; Van Amsterdam, JG	1
Daniel, EE; Janssen, LJ	1
Ahmad, S; Chrétien, P; Daniel, EE; Shen, SH	1
Felder, CC; Jose, PA; McKelvey, AM; Nakamura, KT; Piccio, MM; Robillard, JE	1
Crooke, ST; Nakada, MT; Stadel, JM	1
Boehm, C; Houck, WT; Roberts, J; Tumer, N	1
Earley, KJ; Tenner, TE; Young, JA	1
Earley, KJ; Tenner, TE; Yen, YC; Young, JA	1
Booze, RM; Crisostomo, EA; Davis, JN	1
Johnson, EW; Molinoff, PB; Wolfe, BB	1
Artymyshyn, RP; Battisti, WP; Murray, M	1
Fowler, JC; O'Donnell, JM	1
Frame, LH; Liang, BT; Molinoff, PB	1
Palacios, JM; Pazos, A; Probst, A	1
Frazer, A; O'Donnell, J; Ordway, G; Vos, P; Wolfe, B	1
Frazer, A; O'Donnell, JM; Ordway, GA	1
Alden, BM; Jose, PA; Matherne, GP; Nakamura, KT; Robillard, JE	1
Murugaiah, KD; O'Donnell, JM	1
Aller, MI; Candelas, MA; Fernández-López, A; Pazos, A; Revilla, V; Soria, C	1
Chiyotani, A; Konno, K; Takeuchi, S; Tamaoki, J; Yamauchi, F; Yamawaki, I	1
Duncan, GE; Kirkman, JA; Little, KY	1
Feller, DR; Konkar, AA; Lezama, EJ; Miller, DD; Salazar-Bookaman, MM	1
Butterworth, RF; Buu, PN; Michalak, A; Rose, C	1
Fernández-López, A; Revilla, R; Revilla, V	1

Other Studies

29 other study(ies) available for ici 89406 and ici 118551

Article	Year
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3	2005
Influence of age on the beta 1- and beta 2-adrenergic receptors in rat liver. Molecular pharmacology, 1992, Volume: 42, Issue:4 Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Membrane; Imidazoles; Liver; Liver Glycogen; Male; Pindolol; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta	1992
Beta adrenergic receptor alterations in diabetic rat prostate: effects of insulin and dietary myoinositol. The Prostate, 1991, Volume: 19, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dihydroalprenolol; Dose-Response Relationship, Drug; Drinking; Inositol; Insulin; Isoproterenol; Male; Organ Size; Propanolamines; Propranolol; Prostate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Streptozocin; Urination	1991
Presynaptic beta-adrenoceptors in guinea pig papillary muscle: evidence for adrenaline-mediated positive feedback on noradrenergic transmission. Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Electric Stimulation; Epinephrine; Feedback; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Papillary Muscles; Phentolamine; Propanolamines; Receptors, Adrenergic, beta; Synaptic Transmission; Tritium	1991
L-dopa facilitates the release of endogenous norepinephrine and dopamine via presynaptic beta 1- and beta 2-adrenoceptors under essentially complete inhibition of L-aromatic amino acid decarboxylase in rat hypothalamic slices. Japanese journal of pharmacology, 1990, Volume: 53, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic beta-Antagonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dopamine; Electric Stimulation; Hydrazines; Hypothalamus; In Vitro Techniques; Kinetics; Levodopa; Male; Norepinephrine; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta	1990
Identification of beta 2-adrenoceptors on guinea pig alveolar macrophages using (-)-3-[125I]iodocyanopindolol. Inflammation, 1990, Volume: 14, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Membrane; Guinea Pigs; Iodine Radioisotopes; Iodocyanopindolol; Macrophages; Male; Pindolol; Propanolamines; Pulmonary Alveoli; Receptors, Adrenergic, beta; Timolol	1990
Characterization of the prejunctional beta adrenoceptors in canine bronchial smooth muscle. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2 Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; Culture Techniques; Dogs; Drug Interactions; Electric Stimulation; Microelectrodes; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta	1990
Characterization of beta adrenoceptors on cultured endothelial cells by radioligand binding. Life sciences, 1990, Volume: 47, Issue:25 Topics: Adrenergic alpha-Antagonists; Albuterol; Animals; Binding, Competitive; Cattle; Cells, Cultured; Endothelium, Vascular; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Pindolol; Propanolamines; Propranolol; Pulmonary Artery; Receptors, Adrenergic, beta	1990
Ontogeny of renal beta adrenoceptors in the sheep. Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:6 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Ethanolamines; Isoproterenol; Kidney; Pindolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Sheep; Vasodilation	1990
Subtype-selective regulation of beta adrenergic receptor-adenylyl cyclase coupling by phorbol esters in 3T3-L1 fibroblasts. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:1 Topics: Adenylyl Cyclases; Alkaloids; Animals; Cell Line; Cyclic AMP; Fibroblasts; Glucocorticoids; Isoproterenol; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Propanolamines; Protein Kinase C; Receptors, Adrenergic, beta; Staurosporine	1990
Cardiac beta-adrenoceptor binding characteristics with age following adrenal demedullation. British journal of pharmacology, 1990, Volume: 99, Issue:1 Topics: Adrenal Medulla; Aging; Animals; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Myocardium; Pindolol; Propanolamines; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta	1990
Characterization of beta-adrenoceptor subtypes in rabbit mononuclear leukocytes. European journal of pharmacology, 1989, Jan-31, Volume: 160, Issue:2 Topics: Animals; Binding, Competitive; In Vitro Techniques; Iodocyanopindolol; Leukocytes, Mononuclear; Male; Myocardium; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta	1989
Functional characterization of beta-adrenoceptor subtypes in rabbit right atria. Life sciences, 1989, Volume: 44, Issue:10 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atrial Function; Binding, Competitive; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Iodocyanopindolol; Isoproterenol; Myocardial Contraction; Norepinephrine; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Stimulation, Chemical; Terbutaline	1989
Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Brain; Guinea Pigs; Iodine Radioisotopes; Male; Pindolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Species Specificity	1989
Regulation of subtypes of beta-adrenergic receptors in rat brain following treatment with 6-hydroxydopamine. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:7 Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Brain; Hydroxydopamines; Iodine Radioisotopes; Male; Norepinephrine; Oxidopamine; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tissue Distribution	1989
Beta 1- and beta 2-adrenergic 125I-pindolol binding sites in the interpeduncular nucleus of the rat: normal distribution and the effects of deafferentation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:7 Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Denervation; Female; Iodine Radioisotopes; Locus Coeruleus; Mesencephalon; Pindolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values; Thalamus; Tissue Distribution	1989
Antagonism of the responses to isoproterenol in the rat hippocampal slice with subtype-selective antagonists. European journal of pharmacology, 1988, Aug-09, Volume: 153, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Cyclic AMP; Electrophysiology; Hippocampus; In Vitro Techniques; Isoproterenol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta	1988
Beta 2-adrenergic receptors contribute to catecholamine-stimulated shortening of action potential duration in dog atrial muscle. Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:13 Topics: Action Potentials; Animals; Atropine; Catecholamines; Dogs; Dose-Response Relationship, Drug; Heart Atria; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Reserpine	1985
Beta-adrenoceptor subtypes in the human brain: autoradiographic localization. Brain research, 1985, Dec-09, Volume: 358, Issue:1-2 Topics: Aged; Autoradiography; Binding, Competitive; Brain; Female; Humans; Iodocyanopindolol; Male; Middle Aged; Pindolol; Propanolamines; Receptors, Adrenergic, beta	1985
Effect of repeated administration of clenbuterol on the regulation of beta-adrenoceptors in the central nervous system of the rat. Ciba Foundation symposium, 1986, Volume: 123 Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Clenbuterol; Cyclic AMP; Ethanolamines; Isoproterenol; Kinetics; Propanolamines; Rats; Receptors, Adrenergic, beta	1986
Effects of clenbuterol on central beta-1 and beta-2 adrenergic receptors of the rat. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: Animals; Cerebellum; Cerebral Cortex; Clenbuterol; Cyclic AMP; Ethanolamines; Isoproterenol; Pindolol; Propanolamines; Rats; Receptors, Adrenergic, beta	1987
Ontogeny of renal hemodynamic response to terbutaline and forskolin in sheep. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2 Topics: Animals; Blood Pressure; Colforsin; Female; Heart Rate; Hemodynamics; Kidney; Pregnancy; Propanolamines; Sheep; Terbutaline; Vasodilation	1988
Facilitation of norepinephrine release from cerebral cortex is mediated by beta 2-adrenergic receptors. Life sciences, 1995, Volume: 57, Issue:20 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cerebral Cortex; Drug Interactions; Electric Stimulation; Norepinephrine; Prenalterol; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Tritium	1995
Identification of beta-adrenoceptors in rat lymph nodes and spleen: an autoradiographic study. European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Binding Sites; Image Processing, Computer-Assisted; Ligands; Lymph Nodes; Male; Pindolol; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Serotonin; Spleen	1994
Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle. Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:1 Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bronchi; Cyclic AMP; Dogs; Ethanolamines; Female; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phentolamine; Pindolol; Propanolamines; Receptors, Adrenergic, beta	1993
Beta-adrenergic receptor subtypes in human pineal gland. Journal of pineal research, 1996, Volume: 20, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Autoradiography; Binding Sites; Female; Humans; Male; Middle Aged; Pindolol; Pineal Gland; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2	1996
Pharmacological study of atypical beta-adrenoceptors in rat esophageal smooth muscle. European journal of pharmacology, 1996, Jul-11, Volume: 308, Issue:1 Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Carbachol; Clenbuterol; Cyclohexane Monoterpenes; Esophagus; Ethanolamines; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Phenoxyacetates; Phenoxypropanolamines; Pindolol; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Serotonin Antagonists; Trachea; Tretoquinol	1996
Evidence for altered central noradrenergic function in experimental acute liver failure in the rat. Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebral Cortex; Chromatography, High Pressure Liquid; Coma; Dopamine; Frontal Lobe; Hippocampus; Hypothalamus; Idazoxan; Liver Failure, Acute; Microdialysis; Norepinephrine; Pindolol; Prazosin; Propanolamines; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Serotonin; Thalamus	1998
A comparative study of the beta-adrenoceptors in higher visual centres of birds. Neuroscience letters, 1998, Nov-06, Volume: 256, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Birds; Male; Propanolamines; Receptors, Adrenergic, beta; Tritium; Visual Pathways	1998