ici 204,219 has been researched along with zileuton in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (39.53) | 18.2507 |
| 2000's | 16 (37.21) | 29.6817 |
| 2010's | 9 (20.93) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Brooks, CD; Summers, JB | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Grisham, MB; Keenan, CM; Vaananen, PM; Wallace, JL | 1 |
| Smith, LJ | 1 |
| Douglas, I; Herrnreiter, A; Leff, AR; Mayer, D; Muñoz, NM; Zhu, X | 1 |
| Spector, SL; Tan, RA | 1 |
| Drazen, JM | 1 |
| Tan, RA | 1 |
| Wenzel, SE | 1 |
| Spector, S; Tan, RA | 1 |
| Busse, WW; Horwitz, RJ; McGill, KA | 1 |
| Drazen, J | 1 |
| Callens, E; Djebbar, R; Ruff, F; Santais, MC | 1 |
| Lane, SJ | 1 |
| Wedekind, CA | 1 |
| Kuna, P; Kupczyk, M | 1 |
| Bisgaard, H | 1 |
| Krawiec, ME; Wenzel, SE | 1 |
| García-Marcos, L; Schuster, A | 1 |
| Spector, SL | 1 |
| Adachi, M; Minoguchi, K | 1 |
| Hayden, ML | 1 |
| Gunning, WT; Kramer, PM; Pereira, MA; Steele, VE | 1 |
| Capella, GL | 1 |
| Valacer, DJ | 1 |
| Kulkarni, SK; Patil, CS; Singh, VP | 1 |
| Ludington, E; Mehra, P; Simon, RA; Stevenson, DD; White, A | 1 |
| Dickerson, KS; Luttermoser, GK; Scow, DT | 1 |
| Funk, AJ; Kosanke, SD; Li, CS; Lokey, SJ; Mandrell, TD; Potters, CF | 1 |
| Butler, BD; Little, T | 1 |
| DeMarcantonio, MA; Han, JK | 1 |
| Gibbons, RD; Joo, MJ; Lee, TA; Schumock, GT; Stayner, LT; Valuck, RJ | 1 |
| Citron, F; Deem, AK; Genovese, G; Perelli, L; Viale, A | 1 |
21 review(s) available for ici 204,219 and zileuton
| Article | Year |
|---|---|
Modulators of leukotriene biosynthesis and receptor activation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene | 1996 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Leukotrienes in asthma. The potential therapeutic role of antileukotriene agents.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Humans; Hydroxyurea; Indoles; Inflammation; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds | 1996 |
Antileukotriene agents.
Topics: Anti-Asthmatic Agents; Asthma; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds | 1997 |
New directions in asthma drug therapy.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chromones; Humans; Hydroxyurea; Indoles; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds | 1998 |
The role of antileukotrienes in asthma management.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
New approaches to anti-inflammatory therapy for asthma.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Dicarboxylic Acids; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Steroids; Sulfonamides; Tosyl Compounds | 1998 |
The role of leukotriene modifiers in the treatment of asthma.
Topics: Animals; Asthma; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds | 1998 |
Clinical pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Randomized Controlled Trials as Topic; Sulfonamides; Tosyl Compounds; Treatment Outcome | 1998 |
[Potential importance of antileukotrienes in the treatment of asthma and other inflammatory diseases: apropos of a new pharmacological class].
Topics: Acetophenones; Adult; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Crohn Disease; Cystic Fibrosis; Haplorhini; Humans; Hydroxyurea; Indazoles; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Psoriasis; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sulfonamides; Tetrazoles; Tosyl Compounds | 1998 |
Leukotriene antagonism in asthma and rhinitis.
Topics: Acetates; Asthma; Bronchi; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotriene D4; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Rhinitis; Sinusitis; Sulfides; Sulfonamides; Tosyl Compounds | 1998 |
[The role of leukotrienes in inflammation and leukotriene inhibitors].
Topics: Acetates; Arachidonate 5-Lipoxygenase; Asthma; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 1999 |
Leukotriene modifiers in pediatric asthma management.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Leukotriene inhibitors and non-steroidal therapies in the treatment of asthma.
Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Phosphodiesterase Inhibitors; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2001 |
Antileukotrienes in asthma: present situation.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chromones; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
[Leukotriene modifiers].
Topics: Acetates; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Practice Guidelines as Topic; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Leukotriene modifiers. Expanded role may be on horizon.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Patient Compliance; Phenylcarbamates; Quinolines; Safety; Steroids; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2000 |
New treatments for asthma: the role of leukotriene modifier agents.
Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Drug Evaluation; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 1999 |
Leukotriene inhibitors in the treatment of allergy and asthma.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Dermatitis, Atopic; Humans; Hydroxyurea; Hypersensitivity; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Sulfonamides; Tosyl Compounds | 2007 |
Systemic therapies in managing sinonasal inflammation.
Topics: Anti-Inflammatory Agents; Combined Modality Therapy; Drug Therapy; Eosinophils; Histamine Antagonists; Humans; Hydroxyurea; Immunologic Factors; Indoles; Leukotriene Antagonists; Otorhinolaryngologic Surgical Procedures; Phenylcarbamates; Rhinitis; Sinusitis; Sulfonamides; Tosyl Compounds | 2010 |
Association between leukotriene-modifying agents and suicide: what is the evidence?
Topics: Acetates; Adverse Drug Reaction Reporting Systems; Cyclopropanes; Drug Labeling; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Suicide; Sulfides; Sulfonamides; Tosyl Compounds; United States; United States Food and Drug Administration | 2011 |
1 trial(s) available for ici 204,219 and zileuton
| Article | Year |
|---|---|
Effect of leukotriene modifier drugs on the safety of oral aspirin challenges.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Desensitization, Immunologic; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 2006 |
21 other study(ies) available for ici 204,219 and zileuton
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrans; Carrier Proteins; Free Radical Scavengers; Gastric Mucosa; Hydroxyurea; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Proteins; Organic Chemicals; Permeability; Phenylcarbamates; Propionates; Quinolines; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Leukotriene B4; Single-Blind Method; Stomach Ulcer; Sulfonamides; Tetrazoles; Tosyl Compounds | 1992 |
Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism.
Topics: Animals; Cell Movement; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotriene B4; Leukotriene D4; Lipoxygenase Inhibitors; Male; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Phenylcarbamates; Receptors, Leukotriene; Receptors, Leukotriene B4; Sulfonamides; Tosyl Compounds; Trachea | 1997 |
Antileukotrienes in chronic urticaria.
Topics: Adult; Chronic Disease; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Male; Phenylcarbamates; Sulfonamides; Tosyl Compounds; Urticaria | 1998 |
Drugs for asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bone Density; Bronchial Spasm; Bronchodilator Agents; Child; Child, Preschool; Choice Behavior; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth; Humans; Hydroxyurea; Indoles; Infant, Newborn; Ipratropium; Lactation; Leukotriene Antagonists; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Tachycardia; Theophylline; Tosyl Compounds | 1999 |
Leukotriene modifiers--a new treatment option for asthma.
Topics: Acetates; Anti-Asthmatic Agents; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome | 1999 |
Drugs for asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Spasm; Child; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth Disorders; Humans; Hydroxyurea; Indoles; Ipratropium; Lactation; Leukotriene Antagonists; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Theophylline; Tosyl Compounds | 2000 |
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI).
Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Budesonide; Chlorpheniramine; Cyclopropanes; Ephedrine; Female; Histamine H1 Antagonists; Humans; Hydroxyurea; Hypersensitivity; Indoles; Ipratropium; Leukotriene Antagonists; Metaproterenol; Nasal Decongestants; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Terbutaline; Tosyl Compounds; Tripelennamine | 2000 |
Safety of antileukotriene agents in asthma management.
Topics: Acetates; Asthma; Churg-Strauss Syndrome; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds | 2001 |
Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dose-Response Relationship, Drug; Female; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Neoplasms; Mice; Mice, Inbred A; Phenylcarbamates; Sulfonamides; Tosyl Compounds; Urethane | 2002 |
Anti-leukotriene drugs in the prevention and treatment of hepatorenal syndrome.
Topics: Acetates; Arachidonic Acid; Cyclopropanes; Hepatorenal Syndrome; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Liver; Phenylcarbamates; Protein Structure, Tertiary; Quinolines; Sulfides; Sulfonamides; Thromboxanes; Tosyl Compounds | 2003 |
Differential effect of zileuton, a 5-lipoxygenase inhibitor, against nociceptive paradigms in mice and rats.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Capillary Permeability; Carrageenan; Cyclopropanes; Dose-Response Relationship, Drug; Female; Hindlimb; Hydroxyurea; Hyperalgesia; Indoles; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Mice; Pain; Pain Measurement; Phenylcarbamates; Quinolines; Rats; Rats, Wistar; Receptors, Leukotriene B4; Sulfides; Sulfonamides; Tosyl Compounds | 2005 |
Effects of leukotriene inhibition on pulmonary morphology in rat pup lungs exposed to hyperoxia.
Topics: Animals; Animals, Newborn; Female; Hydroxyurea; Hyperoxia; Indoles; Leukotriene Antagonists; Lung; Lung Diseases; Male; Oxygen; Phenylcarbamates; Rats; Rats, Sprague-Dawley; Sulfonamides; Tosyl Compounds | 2007 |
Pharmacological intervention to the inflammatory response from decompression sickness in rats.
Topics: Animals; Cyclooxygenase Inhibitors; Decompression Sickness; Hydroxyurea; Indoles; Indomethacin; Inflammation; Isoproterenol; Lipoxygenase Inhibitors; Lysine; Male; Phenylcarbamates; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sulfonamides; Tosyl Compounds | 2008 |
Leukotrienes, a potential target for Covid-19.
Topics: Acetates; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Betacoronavirus; Coronavirus Infections; COVID-19; Cyclopropanes; Cytokine Release Syndrome; Humans; Hydroxyurea; Immunologic Factors; Indoles; Leukotrienes; Pandemics; Phenylcarbamates; Pneumonia, Viral; Quinolines; SARS-CoV-2; Severity of Illness Index; Sulfides; Sulfonamides; Tosyl Compounds | 2020 |