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ici 204,219 and ono 1078

ici 204,219 has been researched along with ono 1078 in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (46.15)18.2507
2000's14 (35.90)29.6817
2010's6 (15.38)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Krell, RD; Shaw, A1
Brooks, CD; Summers, JB1
Belloni, PA; Bolla, M; Capra, V; Folco, GC; Mezzetti, M; Nicosia, S; Rovati, GE1
Gelens, E; Nederkoorn, PH; Schoenmakers, SH; Timmerman, H; Zhang, MQ; Zwaagstra, ME1
Antognoli, GW; Chambers, RJ; Cheng, JB; Marfat, A; Pillar, JS; Shirley, JT; Watson, JW1
Antognoli, GW; Chambers, RJ; Cheng, JB; Kuperman, AV; Liston, TC; Marfat, A; Owens, BS; Pillar, JS; Shirley, JT; Watson, JW1
Abramovitz, M; Austin, CP; Bai, C; Caskey, CT; Chateauneuf, A; Connolly, BM; Coulombe, N; Evans, JF; Figueroa, DJ; Ford-Hutchinson, AW; Greig, GM; Hooks, SB; Hosfield, E; Im, DS; Kargman, S; Liu, Q; Lynch, KR; Metters, KM; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z1
Ames, RS; Bergsma, DJ; Buckley, PT; Chambers, J; Dytko, GM; Ellis, C; Elshourbagy, N; Foley, JJ; Halsey, W; Hay, DW; Herrity, NC; Jenkins, O; Muccitelli, RM; Muir, AI; Murdock, PR; Nuthulaganti, P; Sarau, HM; Sathe, G; Schmidt, DB; Wilson, S1
Antognoli, GW; Chambers, RJ; Cheng, JB; Damon, DB; Kuperman, AV; Liston, TC; Marfat, A; Mebus, C; Pillar, JS; Shirley, JT; Watson, JW1
Abramovitz, M; Austin, CP; Bellefeuille, JN; Cheng, R; Clements, MK; Coulombe, N; Evans, JF; Figueroa, DJ; George, SR; Heise, CE; Im, DS; Liu, Q; Liu, Y; Lynch, KR; Ma, L; Metters, KM; Nguyen, T; O'Dowd, BF; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z1
Capra, V; Nicosia, S; Panigalli, T; Ravasi, S; Rovati, GE1
Anton, P; Bonjoch, J; Diaba, F; Miralpeix, M; Pagès, L; Pérez, D; Puig, C; Soca, L; Vilella, D1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Aratani, Y; Egashira, H; Fujita, M; Hisaichi, K; Ima, M; Imagawa, A; Inoue, A; Ishida, A; Itadani, S; Kadode, M; Kinoshita, A; Kitamine, T; Matsumura, N; Moriguchi, H; Nabe, T; Nakao, T; Nakayama, Y; Nomura, H; Ohmoto, K; Ohta, N; Sekiguchi, T; Sekioka, T; Tajima, Y; Takahashi, S; Takeuchi, J; Ueda, J; Yamaura, Y; Yashiro, K; Yonetomi, Y1
Heitel, P; Kalinowsky, L; Merk, D; Proschak, E1
Baronissi, G; Biagioli, M; Cassiano, C; Catalanotti, B; Conflitti, P; De Luca, P; Fiorillo, B; Fiorucci, S; Limongelli, V; Marchianò, S; Rapacciuolo, P; Roselli, R; Sepe, V; Zampella, A1
Hirose, K; Okawara, S; Sakakibara, H1
Nagai, H; Tanaka, H; Uno, T1
Drazen, JM1
Tan, RA1
Khawaja, AM; Liu, YC; Rogers, DF1
Bernstein, PR1
Ciocca, V; Hay, DW; Leonard, TB; Luttmann, MA; Panettieri, RA; Tan, EM1
Rosenwasser, LJ1
Drazen, JM; Pauwels, R; Wechsler, ME1
Dunn, CJ; Goa, KL1
García-Marcos, L; Schuster, A1
Adachi, M; Minoguchi, K1
Cha, IJ; Kim, MJ; Lee, SS; Lee, YM; Liu, KH; Shin, JG; Shon, JH; Yoon, YR1
Hiyama, Y; Ishimura, M; Kataoka, S; Maeda, T; Suda, M1
Koyabu, N; Kuwano, M; Murakami, H; Nakamura, T; Ohtani, H; Satoh, H; Sawada, Y; Tsujimoto, M; Uchiumi, T; Ushigome, F; Yamashita, F1
Guillevin, L; Guilpain, P; Lhote, F; Mouthon, L; Pagnoux, C1
Culp, JA; Steinke, JW1
Jiang, S; Kamei, C; Kishi, Y; Nakano, Y; Yatsuzuka, R1
Chohnabayashi, N; Nishimura, N; Sugiura, R1
Drakatos, P; Karkoulias, K; Lykouras, D; Sampsonas, F; Spiropoulos, K1
Anderson, R; Feldman, C; Gravett, CM; Steel, HC; Theron, AJ; Tintinger, GR1
Denton, JS; Figueroa, EE; Kramer, M; Strange, K1
Batyuk, A; Besserer-Offroy, É; Bogorodskiy, A; Borshchevskiy, V; Brouillette, R; Cherezov, V; Edelweiss, E; Gordeliy, V; Gusach, A; Han, GW; Hu, H; Ishchenko, A; Katritch, V; Liu, W; Longpré, JM; Luginina, A; Lyapina, E; Marin, E; Mishin, A; Patel, N; Polovinkin, V; Popov, P; Safronova, N; Sarret, P; Shiriaeva, A; Weierstall, U1

Reviews

15 review(s) available for ici 204,219 and ono 1078

ArticleYear
Peptide leukotrienes: current status of research.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: Acetophenones; Humans; Leukotriene Antagonists; Leukotrienes; Molecular Structure; Peptides; Receptors, Immunologic; Receptors, Leukotriene; Tetrazoles

1991
Modulators of leukotriene biosynthesis and receptor activation.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene

1996
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
    Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13

    Topics: Animals; Cyclooxygenase Inhibitors; Drug Discovery; Fatty Acids; Humans; Inflammation; Models, Molecular

2017
[Peptidoleukotriene receptor antagonists in asthma therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:11

    Topics: Asthma; Chromones; Humans; Indoles; Leukotriene Antagonists; Phenylcarbamates; Propionates; Quinolines; SRS-A; Sulfonamides; Tetrazoles; Tosyl Compounds

1996
New directions in asthma drug therapy.
    Hospital practice (1995), 1998, Feb-15, Volume: 33, Issue:2

    Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chromones; Humans; Hydroxyurea; Indoles; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds

1998
The role of antileukotrienes in asthma management.
    Current opinion in pulmonary medicine, 1998, Volume: 4, Issue:1

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

1998
Chemistry and structure--activity relationships of leukotriene receptor antagonists.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:6 Pt 2

    Topics: Acetates; Anti-Asthmatic Agents; Biological Availability; Chromones; Cyclopropanes; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; SRS-A; Structure-Activity Relationship; Sulfides; Sulfonamides; Tosyl Compounds

1998
Zafirlukast: an update of its pharmacology and therapeutic efficacy in asthma.
    Drugs, 2001, Volume: 61, Issue:2

    Topics: Administration, Inhalation; Adolescent; Adult; Aged; Albuterol; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Chromones; Humans; Indoles; Leukotriene Antagonists; Middle Aged; Phenylcarbamates; Salmeterol Xinafoate; Sulfonamides; Tosyl Compounds

2001
Antileukotrienes in asthma: present situation.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:3

    Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chromones; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

2001
[Leukotriene modifiers].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:10

    Topics: Acetates; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Practice Guidelines as Topic; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds

2001
[Antileukotrienes and Churg-Strauss syndrome].
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:5 Pt 2

    Topics: Acetates; Adult; Anti-Asthmatic Agents; Antibodies, Antineutrophil Cytoplasmic; Asthma; Chromones; Churg-Strauss Syndrome; Cohort Studies; Cyclopropanes; Humans; Incidence; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Retrospective Studies; Sulfides; Sulfonamides; Tosyl Compounds

2007
Leukotriene synthesis inhibitors versus antagonists: the pros and cons.
    Current allergy and asthma reports, 2007, Volume: 7, Issue:2

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asthma; Chromones; Cyclopropanes; Humans; Hypersensitivity; Indoles; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds

2007
[Adverse effects of leukotriene-antagonists].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Acetates; Anaphylaxis; Chemical and Drug Induced Liver Injury; Chromones; Cyclopropanes; Drug Interactions; Enzyme Inhibitors; Hematologic Diseases; Humans; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases, Interstitial; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds

2007
Targeting leukotrienes for the treatment of COPD?
    Inflammation & allergy drug targets, 2009, Volume: 8, Issue:4

    Topics: 5-Lipoxygenase-Activating Proteins; Acetates; Arachidonate 5-Lipoxygenase; Bronchoconstriction; Capillary Permeability; Carrier Proteins; CD8-Positive T-Lymphocytes; Cell Movement; Chromones; Cyclopropanes; Eosinophils; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Neutrophils; Phenylcarbamates; Pulmonary Disease, Chronic Obstructive; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

2009
Cysteinyl leukotriene receptor-1 antagonists as modulators of innate immune cell function.
    Journal of immunology research, 2014, Volume: 2014

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetates; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Asthma; Chromones; Cyclopropanes; Gene Expression Regulation; Humans; Immunity, Innate; Immunologic Factors; Indoles; Leukotriene Antagonists; Monocytes; Neutrophils; NF-kappa B; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds

2014

Other Studies

24 other study(ies) available for ici 204,219 and ono 1078

ArticleYear
Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro.
    British journal of pharmacology, 1998, Volume: 123, Issue:3

    Topics: Antigens; Benzopyrans; Binding, Competitive; Bronchi; Humans; In Vitro Techniques; Leukotriene D4; Lung; Muscle Contraction

1998
Development of a three-dimensional CysLT1 (LTD4) antagonist model with an incorporated amino acid residue from the receptor.
    Journal of medicinal chemistry, 1998, Apr-23, Volume: 41, Issue:9

    Topics: Arginine; Flavonoids; Leukotriene Antagonists; Membrane Proteins; Models, Molecular; Molecular Conformation; Quinolines; Receptors, Leukotriene

1998
Development of new chromanol antagonists of leukotriene D4.
    Bioorganic & medicinal chemistry letters, 1998, Jul-21, Volume: 8, Issue:14

    Topics: Animals; Chromans; Chromones; Guinea Pigs; Humans; Indoles; Leukotriene Antagonists; Leukotriene D4; Phenylcarbamates; Protein Binding; Sulfonamides; Tosyl Compounds

1998
Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists.
    Bioorganic & medicinal chemistry letters, 1998, Dec-15, Volume: 8, Issue:24

    Topics: Animals; Anti-Asthmatic Agents; Biological Availability; Guinea Pigs; Humans; Leukotriene Antagonists; Magnetic Resonance Spectroscopy; Membrane Proteins; Quinolines; Rats; Receptors, Leukotriene; Stereoisomerism; Thiazoles; U937 Cells

1998
Characterization of the human cysteinyl leukotriene CysLT1 receptor.
    Nature, 1999, Jun-24, Volume: 399, Issue:6738

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chromosome Mapping; Cloning, Molecular; COS Cells; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Macrophages, Alveolar; Membrane Proteins; Molecular Sequence Data; Muscle, Smooth; Receptors, Leukotriene; Tissue Distribution; Transfection; X Chromosome; Xenopus laevis

1999
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.
    Molecular pharmacology, 1999, Volume: 56, Issue:3

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Biological Transport; Calcium; Cells, Cultured; Cloning, Molecular; Humans; Leukotriene D4; Membrane Proteins; Molecular Sequence Data; Pertussis Toxin; Receptors, Leukotriene; Signal Transduction; Virulence Factors, Bordetella

1999
Discovery of CP-199,330 and CP-199,331: two potent and orally efficacious cysteinyl LT1 receptor antagonists devoid of liver toxicity.
    Bioorganic & medicinal chemistry letters, 1999, Sep-20, Volume: 9, Issue:18

    Topics: Animals; Benzopyrans; Biological Availability; Drug Design; Guinea Pigs; Half-Life; Haplorhini; Leukotriene Antagonists; Liver; Membrane Proteins; Rats; Receptors, Leukotriene; Sulfonamides

1999
Characterization of the human cysteinyl leukotriene 2 receptor.
    The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39

    Topics: Adrenal Medulla; Cloning, Molecular; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Membrane Proteins; Models, Molecular; Myocardium; Receptors, Leukotriene; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; SRS-A; Tissue Distribution

2000
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma.
    Biochemical pharmacology, 2002, Apr-15, Volume: 63, Issue:8

    Topics: Acetates; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cyclopropanes; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides

2002
Synthesis and structure-activity relationships of gamma-carboline derivatives as potent and selective cysLT(1) antagonists.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Carbolines; Chemistry, Pharmaceutical; Drug Design; Guinea Pigs; Humans; Inhibitory Concentration 50; Leukotriene Antagonists; Models, Chemical; Receptors, Leukotriene; Structure-Activity Relationship; Time Factors

2009
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Animals; Asthma; Biological Availability; Butyrates; Dogs; Guinea Pigs; Humans; Indoles; Leukotriene Antagonists; Rats; Receptors, Leukotriene

2015
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1.
    Journal of medicinal chemistry, 2021, 11-25, Volume: 64, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Humans; Leukotriene D4; Macrophages; Mice; Molecular Docking Simulation; Protein Binding; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Structure-Activity Relationship

2021
Cysteinyl leukotrienes do not mediate lipopolysaccharide-induced airway hyperresponsiveness in guinea pigs.
    Prostaglandins, 1996, Volume: 52, Issue:6

    Topics: Acetylcholine; Administration, Inhalation; Animals; Anti-Asthmatic Agents; Bronchoalveolar Lavage Fluid; Chromones; Guinea Pigs; Indoles; Leukotrienes; Lipopolysaccharides; Male; Neutrophils; Phenylcarbamates; Respiratory Hypersensitivity; SRS-A; Sulfonamides; Time Factors; Tosyl Compounds; Tumor Necrosis Factor-alpha

1996
Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro.
    British journal of pharmacology, 1998, Volume: 124, Issue:3

    Topics: Adenosine Triphosphate; Animals; Anti-Asthmatic Agents; Binding, Competitive; Chromones; Cysteine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Mucus; Ovalbumin; Passive Cutaneous Anaphylaxis; Phenylcarbamates; Receptors, Leukotriene; Sulfates; Sulfonamides; Sulfur Radioisotopes; Tosyl Compounds; Trachea

1998
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists.
    American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:3

    Topics: Asthma; Carbachol; Cells, Cultured; Chromones; Dicarboxylic Acids; DNA Replication; Epidermal Growth Factor; Extracellular Matrix Proteins; Gene Expression Regulation; Humans; Indoles; Leukotriene Antagonists; Leukotriene D4; Membrane Proteins; Muscle Contraction; Muscle, Smooth, Vascular; Phenylcarbamates; Receptors, Leukotriene; RNA, Messenger; Sulfonamides; Tosyl Compounds; Trachea; Transforming Growth Factor beta

1998
Leukotriene modifiers: new drugs, old and new reactions.
    The Journal of allergy and clinical immunology, 1999, Volume: 103, Issue:3 Pt 1

    Topics: Acetates; Anti-Asthmatic Agents; Asthma; Autoimmune Diseases; Chromones; Churg-Strauss Syndrome; Cyclopropanes; Drug Hypersensitivity; Eosinophilia; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Lupus Erythematosus, Systemic; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Th2 Cells; Tosyl Compounds

1999
Leukotriene modifiers and Churg-Strauss syndrome: adverse effect or response to corticosteroid withdrawal?
    Drug safety, 1999, Volume: 21, Issue:4

    Topics: Acetates; Adrenal Cortex Hormones; Asthma; Chromones; Churg-Strauss Syndrome; Cyclopropanes; Eosinophils; Female; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds

1999
Potential of pranlukast and zafirlukast in the inhibition of human liver cytochrome P450 enzymes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:5

    Topics: Aryl Hydrocarbon Hydroxylases; Chromones; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Indoles; Kinetics; Leukotriene Antagonists; Microsomes, Liver; Phenylcarbamates; Sulfonamides; Tolbutamide; Tosyl Compounds

2004
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
    Allergology international : official journal of the Japanese Society of Allergology, 2006, Volume: 55, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan

2006
Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:11

    Topics: Acetates; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biological Transport; Biphenyl Compounds; Blotting, Western; Cell Line; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Estrone; Humans; Imidazoles; Indoles; Leukotriene Antagonists; Losartan; Molecular Structure; Organic Anion Transporters, Sodium-Independent; Phenylcarbamates; Quinolines; Structure-Activity Relationship; Sulfides; Sulfonamides; Tetrazoles; Tosyl Compounds; Transfection; Tritium; Valine; Valsartan

2006
Participation in cysteinyl leukotrienes and thromboxane A2 in nasal congestion model in Brown Norway rats.
    International immunopharmacology, 2007, Volume: 7, Issue:11

    Topics: Animals; Benzoquinones; Carbazoles; Chromones; Dose-Response Relationship, Drug; Heptanoic Acids; Indoles; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Rats; Rats, Inbred BN; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Rhinitis; Sneezing; Sulfonamides; Thromboxane A2; Tosyl Compounds

2007
CysLT1 receptor antagonists pranlukast and zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor.
    American journal of physiology. Cell physiology, 2019, 10-01, Volume: 317, Issue:4

    Topics: Anions; Cell Size; Chromones; Epithelial Cells; HEK293 Cells; Humans; Indoles; Leukotriene Antagonists; Leukotriene D4; Membrane Proteins; Phenylcarbamates; Receptors, Leukotriene; Signal Transduction; Sulfonamides; Tosyl Compounds

2019
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
    Science advances, 2019, Volume: 5, Issue:10

    Topics: Anti-Asthmatic Agents; Binding Sites; Chromones; Crystallography, X-Ray; Humans; Indoles; Leukotriene Antagonists; Ligands; Molecular Docking Simulation; Phenylcarbamates; Protein Structure, Tertiary; Receptors, Leukotriene; Recombinant Proteins; Sodium; Sulfonamides; Tosyl Compounds

2019