Page last updated: 2024-08-16

ici 204,219 and leukotriene e4

ici 204,219 has been researched along with leukotriene e4 in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (35.71)	18.2507
2000's	8 (57.14)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Abramovitz, M; Austin, CP; Bai, C; Caskey, CT; Chateauneuf, A; Connolly, BM; Coulombe, N; Evans, JF; Figueroa, DJ; Ford-Hutchinson, AW; Greig, GM; Hooks, SB; Hosfield, E; Im, DS; Kargman, S; Liu, Q; Lynch, KR; Metters, KM; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z	1
Ames, RS; Bergsma, DJ; Buckley, PT; Chambers, J; Dytko, GM; Ellis, C; Elshourbagy, N; Foley, JJ; Halsey, W; Hay, DW; Herrity, NC; Jenkins, O; Muccitelli, RM; Muir, AI; Murdock, PR; Nuthulaganti, P; Sarau, HM; Sathe, G; Schmidt, DB; Wilson, S	1
Abramovitz, M; Austin, CP; Bellefeuille, JN; Cheng, R; Clements, MK; Coulombe, N; Evans, JF; Figueroa, DJ; George, SR; Heise, CE; Im, DS; Liu, Q; Liu, Y; Lynch, KR; Ma, L; Metters, KM; Nguyen, T; O'Dowd, BF; O'Neill, GP; Sawyer, N; Stocco, R; Williams, DL; Zeng, Z	1
Baronissi, G; Biagioli, M; Cassiano, C; Catalanotti, B; Conflitti, P; De Luca, P; Fiorillo, B; Fiorucci, S; Limongelli, V; Marchianò, S; Rapacciuolo, P; Roselli, R; Sepe, V; Zampella, A	1
Binks, S; Björck, T; Boo, K; Dahlén, B; Dahlén, SE; Eliasson, E; Johansson, H; King, B; Kumlin, M; Whitney, J	1
Buckner, CK; England, DM; Fedyna, JS; Krell, RD; Robertson, JL; Saban, R; Will, JA	1
Dollery, CT; O'Connell, F; O'Connor, B; O'Shaughnessy, KM; Taylor, IK; Thomson, H	1
Bäck, M; Brink, C; Dahlén, S; Gascard, J; Mazmanian, G; Norel, X; Walch, L	1
Chan, SC; Feng, TC; Ho, CK; Su, YC; Tsai, JJ	1
Guo, Y; Sun, T; Zhang, H	2
Bäck, M; Sakata, K	1
Bu, X; Pang, B; Wang, C	1
Altraja, A; Halme, M; Laitinen, A; Laitinen, LA; Lindqvist, A	1

Trials

2 trial(s) available for ici 204,219 and leukotriene e4

Article	Year
Potent leukotriene D4 receptor antagonist ICI 204,219 given by the inhaled route inhibits the early but not the late phase of allergen-induced bronchoconstriction. The American review of respiratory disease, 1993, Volume: 147, Issue:6 Pt 1 Topics: Administration, Inhalation; Adult; Allergens; Analysis of Variance; Asthma; Bronchoconstriction; Female; Forced Expiratory Volume; Humans; Indoles; Leukotriene E4; Male; Phenylcarbamates; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Sulfonamides; Time Factors; Tosyl Compounds	1993
Leukotriene E(4)-induced persistent eosinophilia and airway obstruction are reversed by zafirlukast in patients with asthma. The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:2 Topics: Administration, Inhalation; Adult; Airway Obstruction; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Double-Blind Method; Eosinophilia; Female; Forced Expiratory Volume; Humans; Indoles; Leukotriene Antagonists; Leukotriene E4; Lung; Male; Middle Aged; Phenylcarbamates; Sulfonamides; Tosyl Compounds	2005

Article

Year

Potent leukotriene D4 receptor antagonist ICI 204,219 given by the inhaled route inhibits the early but not the late phase of allergen-induced bronchoconstriction.

The American review of respiratory disease, 1993, Volume: 147, Issue:6 Pt 1

Topics: Administration, Inhalation; Adult; Allergens; Analysis of Variance; Asthma; Bronchoconstriction; Female; Forced Expiratory Volume; Humans; Indoles; Leukotriene E4; Male; Phenylcarbamates; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Sulfonamides; Time Factors; Tosyl Compounds

1993

Leukotriene E(4)-induced persistent eosinophilia and airway obstruction are reversed by zafirlukast in patients with asthma.

The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:2

Topics: Administration, Inhalation; Adult; Airway Obstruction; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Double-Blind Method; Eosinophilia; Female; Forced Expiratory Volume; Humans; Indoles; Leukotriene Antagonists; Leukotriene E4; Lung; Male; Middle Aged; Phenylcarbamates; Sulfonamides; Tosyl Compounds

2005

Other Studies

12 other study(ies) available for ici 204,219 and leukotriene e4

Article	Year
Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature, 1999, Jun-24, Volume: 399, Issue:6738 Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chromosome Mapping; Cloning, Molecular; COS Cells; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Macrophages, Alveolar; Membrane Proteins; Molecular Sequence Data; Muscle, Smooth; Receptors, Leukotriene; Tissue Distribution; Transfection; X Chromosome; Xenopus laevis	1999
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor. Molecular pharmacology, 1999, Volume: 56, Issue:3 Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Biological Transport; Calcium; Cells, Cultured; Cloning, Molecular; Humans; Leukotriene D4; Membrane Proteins; Molecular Sequence Data; Pertussis Toxin; Receptors, Leukotriene; Signal Transduction; Virulence Factors, Bordetella	1999
Characterization of the human cysteinyl leukotriene 2 receptor. The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39 Topics: Adrenal Medulla; Cloning, Molecular; Cysteine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lung; Membrane Proteins; Models, Molecular; Myocardium; Receptors, Leukotriene; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; SRS-A; Tissue Distribution	2000
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1. Journal of medicinal chemistry, 2021, 11-25, Volume: 64, Issue:22 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Humans; Leukotriene D4; Macrophages; Mice; Molecular Docking Simulation; Protein Binding; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Structure-Activity Relationship	2021
Inhibition of allergic bronchoconstriction in asthmatics by the leukotriene-antagonist ICI-204,219. Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Humans; Hypersensitivity, Immediate; Indoles; Leukotriene Antagonists; Leukotriene E4; Male; Middle Aged; Phenylcarbamates; SRS-A; Sulfonamides; Tosyl Compounds	1991
An examination of the influence of the epithelium on contractile responses to peptidoleukotrienes and blockade by ICI 204,219 in isolated guinea pig trachea and human intralobar airways. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Animals; Arachidonate 5-Lipoxygenase; Bronchi; Dose-Response Relationship, Drug; Epithelium; Guinea Pigs; Humans; Hydroxyquinolines; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Male; Muscle Contraction; Phenylcarbamates; Quinolines; SRS-A; Sulfonamides; Tosyl Compounds; Trachea	1990
Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes. European journal of pharmacology, 2000, Aug-11, Volume: 401, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Pulmonary Artery; Receptors, Leukotriene; SRS-A; Sulfonamides; Swine; Thromboxane A2; Tosyl Compounds; Vasoconstriction	2000
Enhanced prostaglandin E2 secretion in sputum from asthmatic patients after zafirlukast therapy. Journal of the Formosan Medical Association = Taiwan yi zhi, 2001, Volume: 100, Issue:4 Topics: Adult; Aged; Anti-Asthmatic Agents; Asthma; Blood Proteins; Dinoprostone; Eosinophil Granule Proteins; Humans; Indoles; Leukotriene Antagonists; Leukotriene E4; Maximal Expiratory Flow Rate; Middle Aged; Phenylcarbamates; Ribonucleases; Sputum; Sulfonamides; Tosyl Compounds	2001
[The relationship between eosinophils, activated T lymphocyte, leukotreine and the exercise-induced asthma]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2001, Volume: 24, Issue:6 Topics: Adult; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Biomarkers; Blood Proteins; Eosinophil Granule Proteins; Eosinophils; Female; Forced Expiratory Volume; Humans; Indoles; Interleukin-4; Interleukin-5; Leukotriene Antagonists; Leukotriene E4; Lung; Lymphocyte Activation; Male; Maximal Voluntary Ventilation; Middle Aged; Peak Expiratory Flow Rate; Phenylcarbamates; Receptors, Interleukin-2; Ribonucleases; Sulfonamides; Th2 Cells; Tosyl Compounds	2001
Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma. European journal of pharmacology, 2002, Feb-01, Volume: 436, Issue:1-2 Topics: Animals; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lung; Male; Membrane Proteins; Muscle Contraction; Nitric Oxide Synthase; Nitroarginine; Phenylcarbamates; Propionates; Quinolines; Receptors, Leukotriene; Sulfonamides; Tosyl Compounds	2002
[Study on relationship between leukotrienes and exercise-induced asthma]. Zhonghua yi xue za zhi, 2002, Jan-10, Volume: 82, Issue:1 Topics: Adult; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Female; Humans; Indoles; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Male; Membrane Proteins; Middle Aged; Phenylcarbamates; Receptors, Leukotriene; Sulfonamides; Tosyl Compounds	2002
Effects of leukotriene receptor antagonist on chronic obstructive [correction of obstractive] pulmonary disease induced pulmonary hypertension. Chinese medical journal, 2003, Volume: 116, Issue:3 Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Indoles; Leukotriene Antagonists; Leukotriene E4; Male; Oxygen; Phenylcarbamates; Pulmonary Disease, Chronic Obstructive; Respiration; Sulfonamides; Tosyl Compounds	2003