ici 169369 has been researched along with methysergide in 5 studies
| Studies (ici 169369) | Trials (ici 169369) | Recent Studies (post-2010) (ici 169369) | Studies (methysergide) | Trials (methysergide) | Recent Studies (post-2010) (methysergide) |
|---|---|---|---|---|---|
| 31 | 4 | 0 | 2,935 | 81 | 80 |
| Protein | Taxonomy | ici 169369 (IC50) | methysergide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0021 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 1.631 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.807 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 4.763 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.054 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.943 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.013 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0021 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.054 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.172 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0006 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.162 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Blackburn, T; Edvinsson, L; Eriksen, K; Jansen, I | 1 |
| Frenken, M; Kaumann, AJ | 2 |
| Edwards, D; Hollingsworth, M; Miller, M | 1 |
5 other study(ies) available for ici 169369 and methysergide
| Article | Year |
|---|---|
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
5-hydroxytryptamine antagonistic effects of ICI 169,369, ICI 170,809 and methysergide in human temporal and cerebral arteries.
Topics: Cerebral Arteries; Humans; In Vitro Techniques; Methysergide; Muscle, Smooth, Vascular; Quinolines; Receptors, Serotonin; Serotonin Antagonists; Temporal Arteries; Vasoconstriction | 1991 |
Dimethylation of the activator ICI 169,369 results in a high-affinity partial deactivator, ICI 170,809, of the arterial 5-hydroxytryptamine2 receptor system.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Methylation; Methysergide; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Vasoconstriction | 1989 |
Ergometrine--a partial agonist at 5-HT receptors in the uterus isolated from the oestrogen-primed rat.
Topics: Animals; Ergonovine; Estradiol; Female; In Vitro Techniques; Methysergide; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Uterine Contraction; Uterus | 1988 |
ICI 169,369 is both a competitive antagonist and an allosteric activator of the arterial 5-hydroxytryptamine2 receptor system.
Topics: Allosteric Site; Animals; Arteries; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; In Vitro Techniques; Methysergide; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Vasoconstriction | 1988 |