ici 162846 has been researched along with histamine in 2 studies
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
| Studies (ici 162846) | Trials (ici 162846) | Recent Studies (post-2010) (ici 162846) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 6 | 1 | 2 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | ici 162846 (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA | 1 |
| Baron, JH; Gompertz, RH; Li, SK; Man, WK; Michalowski, AS; Spencer, J | 1 |
2 other study(ies) available for ici 162846 and histamine
| Article | Year |
|---|---|
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum | 2010 |
Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model.
Topics: Adenosine Triphosphatases; Animals; Duodenal Ulcer; Female; Gastric Acid; H(+)-K(+)-Exchanging ATPase; Histamine; Histamine H2 Antagonists; Histamine Release; Mediastinum; Mice; Omeprazole; Pyrazoles | 1991 |