Page last updated: 2024-09-04

ici 162846 and histamine

ici 162846 has been researched along with histamine in 2 studies

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

Compound Research Comparison

Studies
(ici 162846)
Trials
(ici 162846)
Recent Studies (post-2010)
(ici 162846)
Studies
(histamine)
Trials
(histamine)
Recent Studies (post-2010) (histamine)
61237,7181,3723,457

Protein Interaction Comparison

ProteinTaxonomyici 162846 (IC50)histamine (IC50)
Histamine H1 receptorRattus norvegicus (Norway rat)0.1585
Histamine H1 receptorHomo sapiens (human)0.1585

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA1
Baron, JH; Gompertz, RH; Li, SK; Man, WK; Michalowski, AS; Spencer, J1

Other Studies

2 other study(ies) available for ici 162846 and histamine

ArticleYear
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum

2010
Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model.
    Agents and actions, 1991, Volume: 33, Issue:1-2

    Topics: Adenosine Triphosphatases; Animals; Duodenal Ulcer; Female; Gastric Acid; H(+)-K(+)-Exchanging ATPase; Histamine; Histamine H2 Antagonists; Histamine Release; Mediastinum; Mice; Omeprazole; Pyrazoles

1991