Compounds > ici 118233
Page last updated: 2024-09-04

ici 118233 and 1-methyl-3-isobutylxanthine

ici 118233 has been researched along with 1-methyl-3-isobutylxanthine in 2 studies

Compound Research Comparison

Studies
(ici 118233)		Trials
(ici 118233)		Recent Studies (post-2010)
(ici 118233)		Studies
(1-methyl-3-isobutylxanthine)		Trials
(1-methyl-3-isobutylxanthine)		Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
5005,1485279

Protein Interaction Comparison

ProteinTaxonomyici 118233 (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furman, BL; Pyne, NJ; Shafiee-Nick, R1
Dettmer, D; Hermsdorf, T1

Other Studies

2 other study(ies) available for ici 118233 and 1-methyl-3-isobutylxanthine

ArticleYear
Effects of type-selective phosphodiesterase inhibitors on glucose-induced insulin secretion and islet phosphodiesterase activity.
    British journal of pharmacology, 1995, Volume: 115, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Analysis of Variance; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Guanidines; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazines; Pyridazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Thiophenes

1995
Combined effects of insulin and dexamethasone on cyclic AMP phosphodiesterase 3 and glycogen metabolism in cultured rat hepatocytes.
    Cellular signalling, 1998, Volume: 10, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Animals; Bucladesine; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Dexamethasone; Drug Interactions; Glycogen; Insulin; Liver; Molecular Sequence Data; Peptide Fragments; Phosphodiesterase Inhibitors; Pyridazines; Pyrimidines; Rats

1998