Page last updated: 2024-08-24

ibutilide and uk 68798

ibutilide has been researched along with uk 68798 in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (25.00)	18.2507
2000's	25 (69.44)	29.6817
2010's	2 (5.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Keserü, GM	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brunden, MN; Buchanan, LV; Gibson, JK; Kabell, G	1
Baskin, EP; Guinosso, PJ; Hamill, T; Lynch, JJ; Nutt, EM; Salata, JJ; Woods, CM	1
Roden, DM; Snyders, DJ; Yang, T	1
Henderson, C; Kane, K; Tweedie, D	1
Lee, EW; Lee, KS; Tsai, TD	1
Bharucha, D; Kowey, PR; Marinchak, RA; Rials, SJ	1
Baskin, EP; Lynch, JJ	1
Sager, PT	2
Camm, AJ	1
Pickoff, AS; Stolfi, A	1
Conway, DS; Lip, GY	1
Dorian, P; Qi, X	1
Bianconi, L; Castro, A; Santini, M	1
Crijns, HJ; Vos, MA	1
Brendel, J; Busch, AE; Knobloch, K; Peukert, S; Rosenstein, B; Wirth, KJ	1
Kao, W; Kowey, PR; Winkel, E; Yan, GX	1
DeBisschop, M; Lower, DL; Martin, LG; Yamreudeewong, W	1
Khan, MH	1
Chazov, EI; Glushkov, RG; Golitsyn, SP; Iuzhakov, SD; L'vov, AI; Rozenshtraukh, LV; Ruda, MIa	1
Li, WZ	1
Bleich, M; Brendel, J; Busch, AE; Knobloch, K; Rosenstein, B; Wirth, KJ	1
de Groot, MJ; Helliwell, R; Leishman, D; Mitcheson, J; Perry, M; Sanguinetti, MC; Tristani-Firouzi, M	1
Pürerfellner, H	1
Borchard, R; Brandts, B; Dirkmann, D; Meine, M; Prull, MW; Trappe, HJ; Van Bracht, M; Wickenbrock, I	1
Allessie, MA; Blaauw, Y; Gögelein, H; Schotten, U; Tieleman, RG; van Hunnik, A	1
Brendorp, B; Elming, H; Køber, L; Pedersen, OD; Pehrson, S; Torp-Petersen, C	1
Allessie, MA; Blaauw, Y; Neuberger, HR; Schotten, U; van Hunnik, A	1

Reviews

14 review(s) available for ibutilide and uk 68798

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pharmacologic and pharmacokinetic profile of class III antiarrhythmic drugs. The American journal of cardiology, 1997, Oct-23, Volume: 80, Issue:8A Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Humans; Phenethylamines; Sotalol; Sulfonamides	1997
New advances in class III antiarrhythmic drug therapy. Current opinion in cardiology, 1999, Volume: 14, Issue:1 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Denmark; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Postoperative Complications; Potassium Channel Blockers; Randomized Controlled Trials as Topic; Sulfonamides	1999
New advances in class III antiarrhythmic drug therapy. Current opinion in cardiology, 2000, Volume: 15, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2000
Clinical differences between the newer antiarrhythmic agents. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2000, Volume: 1 Suppl C Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2000
New antiarrhythmic agents for atrial fibrillation. Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Hydantoins; Imidazoles; Imidazolidines; Lidocaine; Phenethylamines; Piperazines; Sulfonamides	2001
Antiarrhythmic drugs and ventricular defibrillation energy requirements. Chinese medical journal, 1999, Volume: 112, Issue:12 Topics: Animals; Anti-Arrhythmia Agents; Defibrillators, Implantable; Humans; Phenethylamines; Sotalol; Sulfonamides; Ventricular Fibrillation	1999
New antiarrhythmic drugs for the treatment of atrial fibrillation. Pacing and clinical electrophysiology : PACE, 2002, Volume: 25, Issue:2 Topics: Aminobenzoates; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2002
Myocardial repolarization and drugs. Impossibility to predict the dominance of anti-arrhythmic over pro-arrhythmic effects of drugs due to differential and ventricular electrical remodeling. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2001, Volume: 1, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Disease Models, Animal; Humans; Phenethylamines; Sulfonamides; Tachycardia, Ventricular; Torsades de Pointes	2001
Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Flecainide; Heart Rate; Humans; Phenethylamines; Practice Guidelines as Topic; Propafenone; Quinidine; Stroke; Sulfonamides; Ventricular Dysfunction, Left	2003
Potentially significant drug interactions of class III antiarrhythmic drugs. Drug safety, 2003, Volume: 26, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Drug Interactions; Humans; Phenethylamines; Sotalol; Sulfonamides	2003
Oral class III antiarrhythmics: what is new? Current opinion in cardiology, 2004, Volume: 19, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides; Tachycardia, Supraventricular; Tachycardia, Ventricular; Treatment Outcome	2004
Recent developments in cardiovascular drug therapy: treatment of atrial arrhythmias with new class III drugs and beyond. Current medicinal chemistry. Cardiovascular and hematological agents, 2004, Volume: 2, Issue:1 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Electric Countershock; Electrophysiology; Humans; Hydantoins; Imidazolidines; Pacemaker, Artificial; Phenethylamines; Piperazines; Sulfonamides	2004
A benefit-risk assessment of class III antiarrhythmic agents. Expert opinion on drug safety, 2004, Volume: 3, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Combined Modality Therapy; Defibrillators, Implantable; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazolidines; Ion Transport; Life Tables; Membrane Potentials; Meta-Analysis as Topic; Phenethylamines; Piperazines; Risk Assessment; Sotalol; Sulfonamides; Survival Analysis; Torsades de Pointes; Treatment Outcome	2004

Other Studies

22 other study(ies) available for ibutilide and uk 68798

Article	Year
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Comparative assessment of ibutilide, D-sotalol, clofilium, E-4031, and UK-68,798 in a rabbit model of proarrhythmia. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Heart Conduction System; Heart Rate; Male; Methoxamine; Phenethylamines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Rabbits; Software; Sotalol; Sulfonamides; Torsades de Pointes	1993
Comparison of binding to rapidly activating delayed rectifier K+ channel, IKr, and effects on myocardial refractoriness for class III antiarrhythmic agents. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Binding, Competitive; Chromans; Electrophysiology; Guinea Pigs; Heart Ventricles; Papillary Muscles; Phenethylamines; Piperidines; Potassium Channel Blockers; Potassium Channels; Procainamide; Pyridines; Sotalol; Structure-Activity Relationship; Sulfonamides; Tritium	1995
Ibutilide, a methanesulfonanilide antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells. Concentration-, time-, voltage-, and use-dependent effects. Circulation, 1995, Mar-15, Volume: 91, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Heart; Mice; Patch-Clamp Techniques; Phenethylamines; Potassium Channel Blockers; Sulfonamides; Time Factors	1995
Glibenclamide, but not class III drugs, prevents ischaemic shortening of the refractory period in guinea-pig hearts. European journal of pharmacology, 1993, Aug-24, Volume: 240, Issue:2-3 Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Electrocardiography; Glyburide; Guinea Pigs; Heart; Male; Myocardial Ischemia; Phenethylamines; Phentolamine; Pyrazines; Pyridines; Refractory Period, Electrophysiological; Sulfonamides; Temperature	1993
Membrane activity of class III antiarrhythmic compounds; a comparison between ibutilide, d-sotalol, E-4031, sematilide and dofetilide. European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Phenethylamines; Piperidines; Potassium Channels; Procainamide; Pyridines; Sotalol; Sulfonamides	1993
Differential atrial versus ventricular activities of class III potassium channel blockers. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Atrial Function; Ferrets; Heart; Hydantoins; Imidazoles; Imidazolidines; Male; Papillary Muscles; Phenethylamines; Piperazines; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Sulfonamides; Temperature; Ventricular Function	1998
Comparison of the rate dependent effects of dofetilide and ibutilide in the newborn heart. Pacing and clinical electrophysiology : PACE, 2001, Volume: 24, Issue:5 Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Atrial Function; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Heart Rate; Heart Ventricles; Linear Models; Phenethylamines; Sulfonamides; Ventricular Function	2001
Electrophysiological and antiarrhythmic effects of the novel I(Kur) channel blockers, S9947 and S20951, on left vs. right pig atrium in vivo in comparison with the I(Kr) blockers dofetilide, azimilide, d,l-sotalol and ibutilide. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Atrial Function; Biphenyl Compounds; Cation Transport Proteins; Electrophysiology; Ether-A-Go-Go Potassium Channels; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Kv1.5 Potassium Channel; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Sotalol; Sulfonamides; Swine; Ventricular Function	2002
[Development of original Russian antiarrhythmic drugs of the 3rd class]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 2003, Issue:12 Topics: Adolescent; Adult; Aged; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzamides; Clinical Trials as Topic; Dogs; Electrocardiography; Female; Humans; Male; Middle Aged; Phenethylamines; Potassium Channel Blockers; Purkinje Fibers; Rabbits; Russia; Sulfonamides; Time Factors	2003
[Progress in the clinical use of anti-arrhythmic drugs (I)]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Clinical Trials as Topic; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2003
Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs. Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:7 Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Atropine; Biphenyl Compounds; Chromans; Flecainide; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Propafenone; Propanolamines; Sotalol; Sulfonamides; Swine; Ventricular Function	2004
Structural determinants of HERG channel block by clofilium and ibutilide. Molecular pharmacology, 2004, Volume: 66, Issue:2 Topics: Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Aspartic Acid; Benzopyrans; Binding Sites; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Phenethylamines; Phenylalanine; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Quaternary Ammonium Compounds; Serine; Sulfonamides; Tyrosine; Xenopus laevis	2004
[Perspectives and limitations in the treatment of vagus-induced atrial fibrillation. Insights from cellular pharmacology]. Medizinische Klinik (Munich, Germany : 1983), 2004, Jul-15, Volume: 99, Issue:7 Topics: Adult; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cells, Cultured; Culture Media; Heart Atria; Humans; Membrane Potentials; Phenethylamines; Potassium Channel Blockers; Rats; Sotalol; Sulfonamides; Time Factors; Vagus Nerve	2004
"Early" class III drugs for the treatment of atrial fibrillation: efficacy and atrial selectivity of AVE0118 in remodeled atria of the goat. Circulation, 2004, Sep-28, Volume: 110, Issue:13 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Delayed Rectifier Potassium Channels; Drug Evaluation, Preclinical; Electric Countershock; Female; Goats; Heart Atria; Heart Conduction System; Infusions, Intravenous; Ion Transport; Neural Conduction; Phenethylamines; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Sulfonamides	2004
Cardioversion of persistent atrial fibrillation by a combination of atrial specific and non-specific class III drugs in the goat. Cardiovascular research, 2007, Jul-01, Volume: 75, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Biphenyl Compounds; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Female; Goats; Phenethylamines; Sulfonamides	2007