Page last updated: 2024-08-24

ibutilide and procainamide

ibutilide has been researched along with procainamide in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's6 (42.86)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagashima, R; Nishikawa, T; Tobita, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Sen, S; Sinha, N1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baskin, EP; Guinosso, PJ; Hamill, T; Lynch, JJ; Nutt, EM; Salata, JJ; Woods, CM1
Lee, EW; Lee, KS; Tsai, TD1
Ellenbogen, KA; Stambler, BS; Wood, MA2
Carberry, PA; Dunn, GH; Kowey, PR; Lewis, WR; Perry, KT; Stambler, B; Vanderlugt, JT; Volgman, AS1
Mehra, R; Vereckei, A; Warman, E; Zipes, DP1
Chen, PS; Chou, CC; Fishbein, MC; Hwang, C; Karagueuzian, HS; Lin, SF; Tan, AY; Zhou, S1

Reviews

2 review(s) available for ibutilide and procainamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The mechanisms of atrial fibrillation.
    Journal of cardiovascular electrophysiology, 2006, Volume: 17 Suppl 3

    Topics: Aging; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Biological Clocks; Electrophysiologic Techniques, Cardiac; Humans; Ligaments; Procainamide; Pulmonary Veins; Sulfonamides; Vena Cava, Superior

2006

Trials

3 trial(s) available for ibutilide and procainamide

ArticleYear
Comparative efficacy of intravenous ibutilide versus procainamide for enhancing termination of atrial flutter by atrial overdrive pacing.
    The American journal of cardiology, 1996, May-01, Volume: 77, Issue:11

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Flutter; Double-Blind Method; Electric Countershock; Electrocardiography; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Procainamide; Sulfonamides; Treatment Outcome

1996
Antiarrhythmic actions of intravenous ibutilide compared with procainamide during human atrial flutter and fibrillation: electrophysiological determinants of enhanced conversion efficacy.
    Circulation, 1997, Dec-16, Volume: 96, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Electrophysiology; Female; Humans; Injections, Intravenous; Male; Middle Aged; Procainamide; Sulfonamides; Treatment Outcome

1997
Conversion efficacy and safety of intravenous ibutilide compared with intravenous procainamide in patients with atrial flutter or fibrillation.
    Journal of the American College of Cardiology, 1998, Volume: 31, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Double-Blind Method; Electric Countershock; Female; Humans; Male; Procainamide; Prospective Studies; Sulfonamides; Treatment Outcome

1998

Other Studies

9 other study(ies) available for ibutilide and procainamide

ArticleYear
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
Comparison of binding to rapidly activating delayed rectifier K+ channel, IKr, and effects on myocardial refractoriness for class III antiarrhythmic agents.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Binding, Competitive; Chromans; Electrophysiology; Guinea Pigs; Heart Ventricles; Papillary Muscles; Phenethylamines; Piperidines; Potassium Channel Blockers; Potassium Channels; Procainamide; Pyridines; Sotalol; Structure-Activity Relationship; Sulfonamides; Tritium

1995
Membrane activity of class III antiarrhythmic compounds; a comparison between ibutilide, d-sotalol, E-4031, sematilide and dofetilide.
    European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Phenethylamines; Piperidines; Potassium Channels; Procainamide; Pyridines; Sotalol; Sulfonamides

1993
Comparison of the effects on drug concentrations, electrophysiologic parameters, and termination of atrial fibrillation in dogs when procainamide and ibutilide are delivered into the right atrium versus intravenously.
    Journal of cardiovascular electrophysiology, 2001, Volume: 12, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Circulation; Dogs; Electrophysiology; Female; Femoral Vein; Heart Atria; Hemodynamics; Injections; Injections, Intravenous; Male; Osmolar Concentration; Procainamide; Sulfonamides

2001