Compounds > ibutilide
Page last updated: 2024-08-24

ibutilide and flecainide

ibutilide has been researched along with flecainide in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's15 (75.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Jia, L; Sun, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Sen, S; Sinha, N1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
DiMarco, JP; Jung, F1
Blitzer, M; Reiffel, JA1
Kao, W; Kowey, PR; Winkel, E; Yan, GX1
Bleich, M; Brendel, J; Busch, AE; Knobloch, K; Rosenstein, B; Wirth, KJ1
Khan, IA1
Aicher, F; Bachleitner, T; Eisserer, G; Gatterer, E; Grander, W; Heinze, G; Kühn, P; Lang, W; Niemeth, C; Reisinger, J; Siostrzonek, P; Vanicek, T1
Bonso, A; Glatter, KA; Hongo, RH; Raviele, A; Rossillo, A; Scheinman, MM; Themistoclakis, S; Yang, Y1
Allessie, M; Blaauw, Y; Duytschaever, M1
Scharf, C1
Giacomini, KM; Kim, RB; Liu, K; McBride, BF; Roden, DM; Urban, TJ; Yang, T1
Globits, S; Hirschl, MM; Wollmann, C1

Reviews

4 review(s) available for ibutilide and flecainide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antiarrhythmic drug therapy in the treatment of atrial fibrillation.
    Cardiology clinics, 1996, Volume: 14, Issue:4

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Electrophysiology; Flecainide; Humans; Ion Channels; Quinidine; Sotalol; Sulfonamides

1996
Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches.
    The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Flecainide; Heart Rate; Humans; Phenethylamines; Practice Guidelines as Topic; Propafenone; Quinidine; Stroke; Sulfonamides; Ventricular Dysfunction, Left

2003
[Atrial flutter and fibrillation].
    Praxis, 2005, Nov-09, Volume: 94, Issue:45

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Calcium Channel Blockers; Catheter Ablation; Clinical Trials as Topic; Disopyramide; Electric Countershock; Electrocardiography; Emergencies; Flecainide; Heart Rate; Humans; Middle Aged; Pacemaker, Artificial; Propafenone; Quinidine; Recurrence; Sotalol; Sulfonamides; Treatment Outcome; Vasodilator Agents

2005

Trials

2 trial(s) available for ibutilide and flecainide

ArticleYear
Flecainide versus ibutilide for immediate cardioversion of atrial fibrillation of recent onset.
    European heart journal, 2004, Volume: 25, Issue:15

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cost-Benefit Analysis; Female; Flecainide; Humans; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Single-Blind Method; Sulfonamides

2004
Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents.
    Journal of the American College of Cardiology, 2004, Aug-18, Volume: 44, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Administration Schedule; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Female; Flecainide; Heart Conduction System; Humans; Italy; Male; Middle Aged; Propafenone; Prospective Studies; San Francisco; Sulfonamides; Treatment Outcome

2004

Other Studies

14 other study(ies) available for ibutilide and flecainide

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
The actions of ibutilide and class Ic drugs on the slow sodium channel: new insights regarding individual pharmacologic effects elucidated through combination therapies.
    Journal of cardiovascular pharmacology and therapeutics, 2000, Volume: 5, Issue:3

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Humans; Male; Middle Aged; Propafenone; Prospective Studies; Sodium Channels; Sulfonamides

2000
Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Atropine; Biphenyl Compounds; Chromans; Flecainide; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Propafenone; Propanolamines; Sotalol; Sulfonamides; Swine; Ventricular Function

2004
Pharmacological cardioversion of recent onset atrial fibrillation.
    European heart journal, 2004, Volume: 25, Issue:15

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Flecainide; Humans; Sulfonamides

2004
Consequences of atrial electrical remodeling for the anti-arrhythmic action of class IC and class III drugs.
    Cardiovascular research, 2005, Jul-01, Volume: 67, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Electric Countershock; Electrophysiology; Flecainide; Goats; Models, Animal; Random Allocation; Refractory Period, Electrophysiological; Sotalol; Sulfonamides; Treatment Failure; Ventricular Remodeling

2005
The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:1

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cation Transport Proteins; Electrophysiology; Ether-A-Go-Go Potassium Channels; Flecainide; Gene Expression; Heart; Humans; Immunohistochemistry; In Situ Hybridization; Inhibitory Concentration 50; Myocytes, Cardiac; Organic Cation Transport Proteins; Patch-Clamp Techniques; Potassium Channels; Quinidine; Sulfonamides; Symporters

2009
A 2-year survey of treatment of acute atrial fibrillation in an ED.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:5

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Emergency Service, Hospital; Female; Flecainide; Humans; Male; Middle Aged; Sulfonamides; Time Factors; Treatment Outcome

2011