ibuprofen has been researched along with warfarin in 110 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (7.27) | 18.7374 |
| 1990's | 13 (11.82) | 18.2507 |
| 2000's | 33 (30.00) | 29.6817 |
| 2010's | 44 (40.00) | 24.3611 |
| 2020's | 12 (10.91) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Faller, B; Wohnsland, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ho, A; Marotti, KR; Romero, DL; Sarver, RW; Thorarensen, A; Tian, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Aleman, A; David, E; Minehan, T; Orr, D; Shaktah, LA; Shaktah, R; Tamae, D; Vardanyan, L | 1 |
| Abbrecht, PH; Penner, JA | 1 |
| Levy, G; Slattery, JT | 1 |
| Levy, G; Slattery, JT; Yacobi, A | 1 |
| Tucker, GT | 1 |
| Jenkins, BG; Lauffer, RB | 1 |
| Pullar, T | 1 |
| Henriksson, K; Schulman, S | 1 |
| Royer, GL; Seckman, CE; Welshman, IR | 1 |
| Furst, DE | 1 |
| Aubry, AF; Rahim, S | 1 |
| Nakasaka, T; Okabe, N | 1 |
| Hashizume, N; Okabe, N | 1 |
| Imai, T; Maruyama, T; Okada, T; Otagiri, M; Rahman, MH | 1 |
| Bopp, BA; Kukulka, MJ; Machinist, JM | 1 |
| Gabb, GM | 1 |
| Haruta, A; Kodama, H; Otagiri, M; Suenaga, A; Takamura, N; Tsuruoka, M; Yamasaki, K | 1 |
| Nerli, B; Picó, G; Romanini, D | 1 |
| Kosa, T; Maruyama, T; Otagiri, M | 1 |
| Kosa, T; Maruyama, T; Otagiri, M; Sakai, N; Yahara, S; Yonemura, N | 1 |
| Ding, Y; Lin, B; Zhu, X | 1 |
| Chen, X; Luo, Q; Ni, J; Wang, H; Zhang, Q; Zou, H | 1 |
| Aime, S; Ascenzi, P; Baroni, S; Cipollone, R; Fasano, M; Mattu, M; Vannini, A | 1 |
| Austin, J; Hage, DS; Kim, HS | 2 |
| Tanaka, Y | 1 |
| Brouwers, JR; de Jong-van den Berg, LT; de Vries-Bots, AM; Piersma-Wichers, M; Plat, AW; Slomp, J; van Dijk, AA; van Dijk, KN | 1 |
| Dangles, O; Dufour, C | 1 |
| Maftouh, M; Mangelings, D; Massart, DL; Matthijs, N; Tanret, I; Vander Heyden, Y | 1 |
| Fielding, L; Fletcher, D; Rutherford, S | 1 |
| Feng, R; Mandula, H; Parepally, JM; Smith, QR | 1 |
| Fuentes Pradera, MA; Suárez Delgado, JM; Yanes Vidal, G; Yerga Pozo, G | 1 |
| Hage, DS; Mallik, R | 1 |
| Ascenzi, P; Fanali, G; Fasano, M | 1 |
| Chordia, MD; Li, F; Macdonald, TL; Woodling, KA | 1 |
| Hoshide, S; Kanou, M; Mukoyoshi, M; Muroga, H; Nishimura, S; Taniguchi, K; Umeda, S | 1 |
| Glass, TA; Schwartz, JH; Sclafani, SJ; Sewell, PE | 1 |
| Gao, S; Liu, SP; Xiong, ZY; Zhang, HX | 1 |
| Peuravuori, J; Pihlaja, K | 1 |
| Du, Y; Kou, J; Liu, X; Sun, W; Yu, B | 1 |
| Huang, SD; Jiang, HD; Li, J; Sun, DL; Wu, PS; Ye, YJ | 1 |
| Welling, A | 1 |
| Briscoe, CJ; Hage, DS; Mallik, R; Yoo, MJ | 1 |
| Marin, ML; Miranda, MA; Rohacova, J | 1 |
| Ascenzi, P; Fasano, M | 1 |
| Ito, S; Yamamoto, D | 1 |
| Ascenzi, P; Cao, Y; Coletta, M; Fanali, G; Fasano, M; Tundo, GR | 1 |
| Huang, ZX; Zhang, HX | 1 |
| Kawai, T; Kitagawa, F; Koino, H; Otsuka, K; Sueyoshi, K | 1 |
| Jensen, SE; Juel, J; Langfrits, CS; Pedersen, TB | 1 |
| Kokot, S; Ni, Y; Zhang, F | 1 |
| Arakawa, R; Iwaki, Y; Kawasaki, H | 1 |
| Berka, K; Otyepka, M; Paloncýová, M | 1 |
| Chen, D; Li, X; Lu, Y; Wang, G | 1 |
| Bačić, GG; Mojović, MD; Pavićević, AA; Popović-Bijelić, AD; Šušnjar, SV | 1 |
| Ascenzi, P; Bionducci, M; Colombo, G; Fanali, G; Fasano, M; Leboffe, L; Meli, M; Meneghini, C; Mobilio, S | 1 |
| New, SY; Su, X; Tan, YN; Xie, J; Yu, Y | 1 |
| Harrington, Pde B; Mao, Y; Qu, LB; Yang, R; Yu, L | 1 |
| Li, X; Yang, Z | 1 |
| Dey, J; Ghosh, S | 1 |
| Cheng, F; Fadli, Z; Huang, H; Lu, Y; Nagar, C; Pietsch, M; Shen, D; Tu, YC | 1 |
| Bykov, EE; Durandin, NA; Kaluzhny, DN; Lavrenov, SN; Preobrazhenskaya, MN; Tevyashova, AN; Tsvetkov, VB | 1 |
| Han, J; Li, D; Liu, G; Liu, M; Wang, B; Wang, Z; Yuan, L; Zhang, M | 1 |
| Pansare, AV; Patil, VR; Shedge, AA | 1 |
| Derdau, V; Matter, H; Nazaré, M; Opatz, T; Petry, S; Schreuder, H; Volkmar, J; Wenskowsky, L | 1 |
| Aguilar, MR; Arévalo, H; García-Fernández, L; Martín-Saldaña, S; Palao-Suay, R; Ramírez-Camacho, R; San Román, J; Trinidad, A | 1 |
| Azam, MW; Khan, AU; Khan, SN; Maryam, L; Sharma, A | 1 |
| Dahmardeh, S; Heidari Majd, M; Shahraki, S; Shiri, F | 1 |
| Karimi, J; Khazalpour, S; Moghadam, NH; Saidijam, M; Salehzadeh, S; Tanzadehpanah, H | 1 |
| Foster, DJR; Petito, ES; Sykes, MJ; Ward, MB | 1 |
| Escher, BI; Fischer, FC; Henneberger, L; Mühlenbrink, M | 1 |
| Matter, H; Opatz, T; Petry, SM; Reusch, J; Schreuder, H; Wagner, M; Wenskowsky, L | 1 |
| Khaibrakhmanova, D; Nikiforova, A; Sedov, I | 1 |
| Abdullah, KM; Al Jaseem, MAJ; Naseem, I; Qais, FA; Shamsi, A | 1 |
| Kalhor, HR; Taghikhani, E | 1 |
| Guan, Q; Wang, N; Wang, X; Yu, D; Zhang, G | 1 |
| Bartucci, R; Guzzi, R | 1 |
| Alexandri, E; Avgeropoulos, A; Gerothanassis, IP; Gkalpinos, VK; Karydis-Messinis, A; Moschovas, D; Papamokos, G; Primikyri, A; Tzakos, AG; Venianakis, T | 1 |
| Granica, S; Korczak, M; Piwowarski, JP; Roszkowski, P | 1 |
| Hamid, SJ; Salih, T | 1 |
| Gerothanassis, IP; Kontogianni, VG; Papamokos, G; Primikyri, A; Sakka, M; Venianakis, T | 1 |
| Al-Lohedan, HA; Al-Sanea, ASS; Ali, MS; Jain, M; Muthukumaran, J; Tariq, M | 1 |
6 review(s) available for ibuprofen and warfarin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
A clinical pharmacologist's perspective.
Topics: Animals; Humans; Ibuprofen; Pharmacokinetics; Propranolol; Stereoisomerism; Structure-Activity Relationship; Warfarin | 1991 |
Method development of enantiomer separations by affinity capillary electrophoresis, cyclodextrin electrokinetic chromatography and capillary electrophoresis-mass spectrometry.
Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Electrophoresis, Capillary; Ibuprofen; Ketoprofen; Mass Spectrometry; Static Electricity; Stereoisomerism; Vanilmandelic Acid; Warfarin | 2002 |
[Massive metrorrhagia in a patient under warfarin anticoagulation. Rapid reversal with a concentrated prothrombin complex (Prothromplex Immuno TIM 4 600 IU)].
Topics: Acetazolamide; Adult; Anticoagulants; Behcet Syndrome; Blood Coagulation Factors; Consciousness Disorders; Drug Synergism; Female; Glaucoma, Angle-Closure; Humans; Ibuprofen; International Normalized Ratio; Lupus Coagulation Inhibitor; Metrorrhagia; Thrombophilia; Warfarin | 2006 |
Allostery in a monomeric protein: the case of human serum albumin.
Topics: Allosteric Regulation; Animals; Binding Sites; Heme; Humans; Ibuprofen; Serum Albumin; Warfarin | 2010 |
Molecular Modeling Approaches for the Prediction of Selected Pharmacokinetic Properties.
Topics: Administration, Oral; Humans; Ibuprofen; Models, Molecular; Quantitative Structure-Activity Relationship; Serum Albumin, Human; Warfarin | 2018 |
2 trial(s) available for ibuprofen and warfarin
| Article | Year |
|---|---|
Lack of interaction between ibuprofen and warfarin.
Topics: Adult; Blood Coagulation Tests; Clinical Trials as Topic; Drug Interactions; Humans; Ibuprofen; Male; Middle Aged; Phenylpropionates; Prothrombin Time; Thromboplastin; Time Factors; Warfarin | 1975 |
Safety profile: fifteen years of clinical experience with ibuprofen.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Proteins; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Eruptions; Drug Interactions; Drug Tolerance; Gastrointestinal Diseases; Humans; Ibuprofen; Kidney Diseases; Liver Function Tests; Warfarin | 1984 |
102 other study(ies) available for ibuprofen and warfarin
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor.
Topics: Albumins; Anti-Bacterial Agents; Binding Sites; Calorimetry; Fluorescence; Humans; ortho-Aminobenzoates; Protein Binding | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Synthesis and Stereochemical Assignment of Conioidine A: DNA- and HSA-Binding Studies of the Four Diastereomers.
Topics: Binding Sites; Binding, Competitive; Calorimetry; Circular Dichroism; DNA; Ethidium; Molecular Docking Simulation; Molecular Structure; Netropsin; Proline; Pyrrolidines; Serum Albumin, Human; Solanaceous Alkaloids; Spectrometry, Fluorescence; Stereoisomerism | 2020 |
Effect of ibuprofen on protein binding of warfarin in human serum.
Topics: Binding Sites; Blood Proteins; Humans; Ibuprofen; Phenylpropionates; Protein Binding; Warfarin | 1977 |
Comparative pharmacokinetics of coumarin anticoagulants XXV: Warfarin-ibuprofen interaction in rats.
Topics: Animals; Blood Coagulation; Blood Proteins; Half-Life; Ibuprofen; Kinetics; Male; Metabolic Clearance Rate; Phenylpropionates; Protein Binding; Rats; Time Factors; Warfarin | 1977 |
Detection of site-specific binding and co-binding of ligands to human serum albumin using 19F NMR.
Topics: Allosteric Regulation; Humans; Ibuprofen; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation; Serum Albumin; Tryptophan; Warfarin | 1990 |
Interaction of ibuprofen and warfarin on primary haemostasis.
Topics: Adolescent; Adult; Aged; Bleeding Time; Drug Interactions; Hemostasis; Humans; Ibuprofen; Warfarin | 1989 |
Interaction of ibuprofen and warfarin on primary haemostasis.
Topics: Aged; Bleeding Time; Drug Interactions; Female; Hemostasis; Humans; Ibuprofen; Male; Middle Aged; Platelet Count; Rheumatic Diseases; Warfarin | 1989 |
Use of ibuprofen in unusual circumstances.
Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersensitivity; Drug Interactions; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Kidney; Kinetics; Lithium; Liver; Lupus Erythematosus, Systemic; Mixed Connective Tissue Disease; Phenytoin; Platelet Aggregation; Prostaglandins E; Warfarin | 1984 |
Location of binding sites on immobilized human serum albumin for some nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin; Warfarin | 1995 |
Drug binding properties of glycosylated bovine serum albumin as measured by circular dichroism.
Topics: Binding Sites; Circular Dichroism; Flufenamic Acid; Glycosylation; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin, Bovine; Warfarin | 1994 |
Drug binding properties of glycosylated human serum albumin as measured by fluorescence and circular dichroism.
Topics: Binding Sites; Circular Dichroism; Dansyl Compounds; Flufenamic Acid; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Ibuprofen; Phenylbutazone; Proline; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin | 1994 |
Study of interaction of carprofen and its enantiomers with human serum albumin--II. Stereoselective site-to-site displacement of carprofen by ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Carbazoles; Circular Dichroism; Dialysis; Humans; Ibuprofen; Mathematics; Models, Chemical; Phenylbutazone; Serum Albumin; Stereoisomerism; Warfarin | 1993 |
In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.
Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Anticoagulants; Blood Proteins; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hematocrit; Humans; Hydroxylation; Hydroxyurea; Ibuprofen; In Vitro Techniques; Isotope Labeling; Lipoxygenase Inhibitors; Male; Naproxen; Prednisolone; Protein Binding; Salicylates; Stereoisomerism; Terfenadine; Theophylline; Warfarin | 1995 |
Fatal outcome of interaction between warfarin and a non-steroidal anti-inflammatory drug.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Interactions; Fatal Outcome; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Warfarin | 1996 |
Mode of interaction of loop diuretics with human serum albumin and characterization of binding site.
Topics: Binding Sites; Diuretics; Fluorescent Dyes; Furosemide; Humans; Ibuprofen; Lysine; Protein Binding; Serum Albumin; Sulfonamides; Warfarin | 1996 |
Structural specificity requirements in the binding of beta lactam antibiotics to human serum albumin.
Topics: Acid-Base Equilibrium; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Binding Sites; Binding, Competitive; Cephalosporins; Coumarins; Esterases; Fatty Acids; Glycosylation; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indicators and Reagents; Kinetics; Ligands; Lysine; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Ultrafiltration | 1997 |
Species differences of serum albumins: I. Drug binding sites.
Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Humans; Ibuprofen; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Rabbits; Rats; Serum Albumin; Warfarin | 1997 |
Species differences of serum albumins: III. Analysis of structural characteristics and ligand binding properties during N-B transitions.
Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ligands; Phenylbutazone; Protein Conformation; Rabbits; Rats; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Warfarin | 1998 |
Study of interaction between drug enantiomers and serum albumin by capillary electrophoresis.
Topics: Binding, Competitive; Bupivacaine; Electrophoresis, Capillary; Ibuprofen; Isomerism; Protein Binding; Serum Albumin; Verapamil; Warfarin | 1999 |
Synthesis and characteristics of the human serum albumin-triazine chiral stationary phase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atropine; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fenoprofen; Glutamic Acid; Humans; Ibuprofen; Naproxen; Protein Binding; Serum Albumin; Silicon Dioxide; Spectrophotometry, Ultraviolet; Stereoisomerism; Triazines; Tryptophan; Warfarin | 2000 |
Effect of ibuprofen and warfarin on the allosteric properties of haem-human serum albumin. A spectroscopic study.
Topics: Allosteric Site; Binding Sites; Electron Spin Resonance Spectroscopy; Heme; Humans; Ibuprofen; In Vitro Techniques; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Binding; Protein Conformation; Serum Albumin; Spectrophotometry; Warfarin | 2001 |
Identification of drug-binding sites on human serum albumin using affinity capillary electrophoresis and chemically modified proteins as buffer additives.
Topics: 2-Hydroxy-5-nitrobenzyl Bromide; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Buffers; Chemical Warfare Agents; Dextrans; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Molecular Structure; Serum Albumin; Suprofen; Tetranitromethane; Tryptophan; Warfarin | 2002 |
Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype.
Topics: Acenocoumarol; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Chi-Square Distribution; Cohort Studies; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Female; Genotype; Humans; Ibuprofen; International Normalized Ratio; Male; Middle Aged; Naproxen; Retrospective Studies; Sex Factors; Time Factors; Warfarin | 2004 |
Screening major binding sites on human serum albumin by affinity capillary electrophoresis.
Topics: 2-Hydroxy-5-nitrobenzyl Bromide; Apazone; Benzodiazepines; Electrophoresis, Capillary; Humans; Ibuprofen; Indoles; Protein Binding; Serum Albumin; Tetranitromethane; Tryptophan; Warfarin | 2004 |
Flavonoid-serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy.
Topics: Binding Sites; Flavonoids; Humans; Ibuprofen; Protein Binding; Quercetin; Serum Albumin; Spectrometry, Fluorescence; Warfarin | 2005 |
Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases.
Topics: Acetonitriles; Buffers; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Hexobarbital; Hydrogen-Ion Concentration; Ibuprofen; Pharmaceutical Preparations; Polysaccharides; Stereoisomerism; Temperature; Warfarin | 2005 |
Determination of protein-ligand binding affinity by NMR: observations from serum albumin model systems.
Topics: Animals; Calorimetry; Cattle; Ibuprofen; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Naproxen; Protein Binding; Proteins; Salicylates; Serum Albumin; Tryptophan; Warfarin | 2005 |
Role of site-specific binding to plasma albumin in drug availability to brain.
Topics: Animals; Binding, Competitive; Biological Availability; Brain; Ibuprofen; Male; Perfusion; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Serum Albumin; Tolbutamide; Ultrafiltration; Valproic Acid; Warfarin | 2006 |
Development of an affinity silica monolith containing human serum albumin for chiral separations.
Topics: Chromatography, Affinity; Humans; Ibuprofen; Methylmethacrylates; Models, Chemical; Particle Size; Permeability; Pressure; Reproducibility of Results; Schiff Bases; Serum Albumin; Silicon Dioxide; Stereoisomerism; Surface Properties; Technology, Pharmaceutical; Tryptophan; Warfarin | 2008 |
Effect of prototypic drugs ibuprofen and warfarin on global chaotropic unfolding of human serum heme-albumin: a fast-field-cycling 1H-NMR relaxometric study.
Topics: Humans; Ibuprofen; Magnetic Resonance Spectroscopy; Methemalbumin; Protein Conformation; Protein Denaturation; Protein Folding; Thermodynamics; Warfarin | 2007 |
Irreversible alkylation of human serum albumin by zileuton metabolite 2-acetylbenzothiophene-S-oxide: a potential model for hepatotoxicity.
Topics: Alkylation; Anti-Asthmatic Agents; Binding, Competitive; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Half-Life; Humans; Hydroxyurea; Ibuprofen; Models, Biological; Serum Albumin; Tandem Mass Spectrometry; Thiophenes; Warfarin | 2007 |
In vitro drug-drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition.
Topics: Blood Proteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Febuxostat; Glucuronosyltransferase; Humans; Ibuprofen; In Vitro Techniques; Male; Microsomes, Liver; Protein Binding; Thiazoles; Warfarin; Xanthine Oxidase | 2008 |
Acute gonadal vein thrombosis secondary to terminal ileitis and thrombophilia.
Topics: Acute Disease; Adult; Diagnosis, Differential; Fluid Therapy; Humans; Ibuprofen; Ileitis; Ketorolac Tromethamine; Male; Platelet Aggregation Inhibitors; Pressure; Testis; Thrombophilia; Thrombosis; Tomography, X-Ray Computed; Warfarin | 2008 |
Fluorometric probing on the binding of hematoxylin to serum albumin.
Topics: Hematoxylin; Ibuprofen; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Thermodynamics; Warfarin | 2009 |
Phototransformations of selected pharmaceuticals under low-energy UVA-vis and powerful UVB-UVA irradiations in aqueous solutions--the role of natural dissolved organic chromophoric material.
Topics: Carbamazepine; Ibuprofen; Kinetics; Metoprolol; Molecular Structure; Molecular Weight; Nitrates; Photochemical Processes; Solid Phase Extraction; Solubility; Solutions; Ultraviolet Rays; Warfarin | 2009 |
Study on the interaction of levocetirizine dihydrochloride with human serum albumin by molecular spectroscopy.
Topics: Binding Sites; Calcium; Cetirizine; Circular Dichroism; Dansyl Compounds; Glycosylation; Humans; Ibuprofen; Ions; Kinetics; Metals; Proline; Protein Structure, Secondary; Serum Albumin; Spectrometry, Fluorescence; Temperature; Warfarin | 2009 |
Stereoselective protein binding of tetrahydropalmatine enantiomers in human plasma, HSA, and AGP, but not in rat plasma.
Topics: Animals; Berberine Alkaloids; Binding, Competitive; Drug Interactions; Humans; Ibuprofen; Imipramine; Male; Mifepristone; Orosomucoid; Plasma; Protein Binding; Rats; Rats, Sprague-Dawley; Serum Albumin; Stereoisomerism; Substrate Specificity; Warfarin | 2010 |
Ibuprofen and warfarin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Cellulitis; Drug Interactions; Emergency Treatment; Humans; Ibuprofen; Insect Bites and Stings; Warfarin | 2009 |
Analysis of drug-protein binding by ultrafast affinity chromatography using immobilized human serum albumin.
Topics: Chromatography, Affinity; Humans; Ibuprofen; Imipramine; Immobilized Proteins; Kinetics; Protein Binding; Serum Albumin; Warfarin | 2010 |
Complexes between fluorescent cholic acid derivatives and human serum albumin. a photophysical approach to investigate the binding behavior.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Binding Sites; Cholic Acid; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Ibuprofen; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin | 2010 |
Identification of two bromocresol purple binding sites on human serum albumin.
Topics: Binding Sites; Bromcresol Purple; Humans; Hydrogen-Ion Concentration; Ibuprofen; Myristic Acid; Propofol; Serum Albumin; Warfarin | 2010 |
Ibuprofen and warfarin modulate allosterically ferrous human serum heme-albumin nitrosylation.
Topics: Allosteric Regulation; Anti-Inflammatory Agents, Non-Steroidal; Heme; Humans; Ibuprofen; Nitric Oxide; Protein Conformation; Serum Albumin; Warfarin | 2011 |
Biochemical evaluation of a synthesized isoflavone-selenium complex by molecular spectra.
Topics: Albumins; Animals; Binding Sites; Cattle; Ibuprofen; Isoflavones; Organoselenium Compounds; Protein Binding; Selenium Compounds; Serum Albumin, Bovine; Thermodynamics; Warfarin | 2012 |
Highly sensitive chiral analysis in capillary electrophoresis with large-volume sample stacking with an electroosmotic flow pump.
Topics: Abscisic Acid; Amino Acids; beta-Cyclodextrins; Electroosmosis; Electrophoresis, Capillary; Humans; Ibuprofen; Limit of Detection; Male; Models, Chemical; Reproducibility of Results; Stereoisomerism; Warfarin | 2012 |
Administration of tramadol or ibuprofen increases the INR level in patients on warfarin.
Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Atrial Fibrillation; Back Pain; Drug Interactions; Humans; Ibuprofen; International Normalized Ratio; Male; Tramadol; Warfarin | 2013 |
Enantioselective binding interaction of the metolachlor pesticide enatiomers with bovine serum albumin--a spectroscopic analysis study.
Topics: Absorption; Acetamides; Animals; Binding Sites; Binding, Competitive; Cattle; Ibuprofen; Kinetics; Least-Squares Analysis; Multivariate Analysis; Pesticides; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Thermodynamics; Warfarin | 2012 |
Human serum albumin-modified Fe3O4 magnetic nanoparticles for affinity-SALDI-MS of small-molecule drugs in biological liquids.
Topics: Camptothecin; Ferrosoferric Oxide; Humans; Ibuprofen; Magnetite Nanoparticles; Molecular Weight; Phenytoin; Sensitivity and Specificity; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Warfarin | 2012 |
Molecular insight into affinities of drugs and their metabolites to lipid bilayers.
Topics: Caffeine; Cell Membrane; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Ibuprofen; Lipid Bilayers; Molecular Dynamics Simulation; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics; Xenobiotics | 2013 |
Binding of ascorbic acid and α-tocopherol to bovine serum albumin: a comparative study.
Topics: Adsorption; alpha-Tocopherol; Ascorbic Acid; Binding Sites; Calorimetry; Entropy; Hydrogen Bonding; Ibuprofen; Protein Binding; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Tryptophan; Tyrosine; Warfarin | 2014 |
Binding of doxyl stearic spin labels to human serum albumin: an EPR study.
Topics: Ascorbic Acid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Humans; Ibuprofen; Protein Binding; Serum Albumin; Spin Labels; Temperature; Warfarin | 2014 |
The five-to-six-coordination transition of ferric human serum heme-albumin is allosterically-modulated by ibuprofen and warfarin: a combined XAS and MD study.
Topics: Absorptiometry, Photon; Allosteric Regulation; Heme; Humans; Ibuprofen; Iron; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Serum Albumin; Warfarin | 2014 |
Protein-based fluorescent metal nanoclusters for small molecular drug screening.
Topics: Drug Evaluation, Preclinical; Fluorescent Dyes; Gold; Ibuprofen; Nanostructures; Phenytoin; Serum Albumin; Sulfanilamide; Sulfanilamides; Warfarin | 2014 |
A novel method for the study of molecular interaction by using microscale thermophoresis.
Topics: Animals; Binding, Competitive; Cattle; Fluorescein-5-isothiocyanate; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Kinetics; Models, Molecular; Motion; Protein Aggregates; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Thermodynamics; Warfarin | 2015 |
Interaction of oridonin with human serum albumin by isothermal titration calorimetry and spectroscopic techniques.
Topics: Binding Sites; Calorimetry; Diterpenes, Kaurane; Humans; Hydrogen Bonding; Ibuprofen; Serum Albumin; Spectrometry, Fluorescence; Warfarin | 2015 |
Binding of Fatty Acid Amide Amphiphiles to Bovine Serum Albumin: Role of Amide Hydrogen Bonding.
Topics: Amides; Calorimetry; Circular Dichroism; Fatty Acids; Hydrogen Bonding; Ibuprofen; Micelles; Microscopy, Fluorescence; Models, Molecular; Molecular Structure; Protein Conformation; Sarcosine; Serum Albumin, Bovine; Spectrum Analysis; Surface Tension; Surface-Active Agents; Thermodynamics; Warfarin | 2015 |
A novel algorithm for analyzing drug-drug interactions from MEDLINE literature.
Topics: Algorithms; Contraindications; Drug Interactions; Enzymes; Furosemide; Humans; Hydrolysis; Ibuprofen; MEDLINE; Sertraline; Warfarin | 2015 |
Quantitative parameters of complexes of tris(1-alkylindol-3-yl)methylium salts with serum albumin: Relevance for the design of drug candidates.
Topics: Binding Sites; Circular Dichroism; Humans; Ibuprofen; Indoles; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Salts; Serum Albumin; Spectrometry, Fluorescence; Thermodynamics; Warfarin | 2016 |
Competitive binding of (-)-epigallocatechin-3-gallate and 5-fluorouracil to human serum albumin: A fluorescence and circular dichroism study.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Binding Sites; Binding, Competitive; Catechin; Circular Dichroism; Drug Synergism; Fluorouracil; Humans; Ibuprofen; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Warfarin | 2017 |
Discrete SeNPs-Macromolecule Binding Manipulated by Hydrophilic Interaction.
Topics: Animals; Calorimetry, Differential Scanning; Cattle; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Macromolecular Substances; Nanoparticles; Selenium; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Warfarin | 2018 |
Identification and Characterization of a Single High-Affinity Fatty Acid Binding Site in Human Serum Albumin.
Topics: Azoles; Binding Sites; Crystallography, X-Ray; Fatty Acids; Fluorescence Resonance Energy Transfer; Humans; Ibuprofen; Molecular Dynamics Simulation; Nitrobenzenes; Protein Binding; Protein Domains; Serum Albumin, Human; Warfarin | 2018 |
pH-sensitive polymeric nanoparticles with antioxidant and anti-inflammatory properties against cisplatin-induced hearing loss.
Topics: alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cisplatin; Coumarins; Dexamethasone; Hearing Loss; Hydrogen-Ion Concentration; Ibuprofen; Nanoparticles; Polymers; Rats, Wistar; Thiazoles | 2018 |
Understanding the mode of binding mechanism of doripenem to human serum albumin: Spectroscopic and molecular docking approaches.
Topics: Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Diazepam; Doripenem; Humans; Hydrogen Bonding; Ibuprofen; Indomethacin; Kinetics; Molecular Docking Simulation; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Serum Albumin, Human; Solutions; Static Electricity; Temperature; Thermodynamics; Warfarin | 2018 |
Anti-cancer study and whey protein complexation of new lanthanum(III) complex with the aim of achieving bioactive anticancer metal-based drugs.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carrier Proteins; Cattle; Cell Death; Computer Simulation; Fluorescence Resonance Energy Transfer; Humans; Hydrogen-Ion Concentration; Ibuprofen; Lactoglobulins; Lanthanum; MCF-7 Cells; Molecular Conformation; Molecular Docking Simulation; Protein Structure, Secondary; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Warfarin; Whey Proteins | 2019 |
In vitro cytotoxicity and DNA/HSA interaction study of triamterene using molecular modelling and multi-spectroscopic methods.
Topics: Animals; Antineoplastic Agents; Binding, Competitive; Cell Line, Tumor; Cell Survival; DNA; HCT116 Cells; Humans; Ibuprofen; Mice; Molecular Docking Simulation; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Triamterene; Warfarin | 2019 |
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cattle; Cells, Cultured; Diclofenac; Genistein; HEK293 Cells; Humans; Ibuprofen; Kinetics; Liposomes; Naproxen; Phospholipids; Serum Albumin, Bovine; Solid Phase Microextraction; Torsemide; Warfarin | 2019 |
Resolving Binding Events on the Multifunctional Human Serum Albumin.
Topics: 4-Chloro-7-nitrobenzofurazan; Binding Sites; Boron Compounds; Crystallography, X-Ray; Fluorescence; Humans; Ibuprofen; Lauric Acids; Molecular Dynamics Simulation; Molecular Structure; Serum Albumin, Human; Warfarin | 2020 |
Evaluation of the binding properties of drugs to albumin from DSC thermograms.
Topics: Calorimetry, Differential Scanning; Ibuprofen; Isoniazid; Naproxen; Protein Binding; Serum Albumin, Bovine; Warfarin | 2020 |
Mechanistic insight into glycation inhibition of human serum albumin by vitamin B9: Multispectroscopic and molecular docking approach.
Topics: Binding Sites; Circular Dichroism; Folic Acid; Glycation End Products, Advanced; Glycosylation; Humans; Ibuprofen; Lysine; Molecular Docking Simulation; Osmolar Concentration; Protein Carbonylation; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence; Spectrum Analysis; Sulfhydryl Compounds; Thermodynamics; Warfarin | 2021 |
Probe into the Molecular Mechanism of Ibuprofen Interaction with Warfarin Bound to Human Serum Albumin in Comparison to Ascorbic and Salicylic Acids: Allosteric Inhibition of Anticoagulant Release.
Topics: Anticoagulants; Binding Sites; Humans; Ibuprofen; Molecular Docking Simulation; Protein Binding; Salicylates; Serum Albumin; Serum Albumin, Human; Warfarin | 2021 |
The interaction of folate-modified Bletilla striata polysaccharide-based micelle with bovine serum albumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Anticoagulants; Cell Line, Tumor; Doxorubicin; Folic Acid; Ibuprofen; Mice; Micelles; Models, Molecular; Polysaccharides; Protein Binding; Protein Conformation; Protein Domains; Serum Albumin, Bovine; Warfarin | 2021 |
Interactive multiple binding of oleic acid, warfarin and ibuprofen with human serum albumin revealed by thermal and fluorescence studies.
Topics: Binding Sites; Humans; Ibuprofen; Oleic Acid; Protein Binding; Serum Albumin, Human; Warfarin | 2022 |
NMR and computational studies reveal novel aspects in molecular recognition of unsaturated fatty acids with non-labelled serum albumin.
Topics: alpha-Linolenic Acid; Amino Acids; Binding Sites; Fatty Acids; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Ibuprofen; Ligands; Linoleic Acids; Magnetic Resonance Spectroscopy; Oleic Acids; Protein Binding; Serum Albumin; Warfarin | 2022 |
Conjugates of urolithin A with NSAIDs, their stability, cytotoxicity, and anti-inflammatory potential.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Coumarins; Humans; Ibuprofen | 2022 |
Design, Synthesis, and Anti-Inflammatory Activity of Some Coumarin Schiff Base Derivatives: In silico and in vitro Study.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Coumarins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Inflammation; Ligands; Molecular Docking Simulation; Schiff Bases | 2022 |
Structural Basis of Artemisinin Binding Sites in Serum Albumin with the Combined Use of NMR and Docking Calculations.
Topics: Artemisinins; Binding Sites; Biological Products; Complex Mixtures; Humans; Ibuprofen; Ligands; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human; Warfarin | 2022 |
Detailed Experimental and In Silico Investigation of Indomethacin Binding with Human Serum Albumin Considering Primary and Secondary Binding Sites.
Topics: Binding Sites; Circular Dichroism; Hemin; Humans; Ibuprofen; Indomethacin; Molecular Docking Simulation; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Warfarin | 2023 |