ibuprofen and warfarin

ibuprofen has been researched along with warfarin in 110 studies

Research

Studies (110)

TimeframeStudies, this research(%)All Research%
pre-19908 (7.27)18.7374
1990's13 (11.82)18.2507
2000's33 (30.00)29.6817
2010's44 (40.00)24.3611
2020's12 (10.91)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ho, A; Marotti, KR; Romero, DL; Sarver, RW; Thorarensen, A; Tian, F1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aleman, A; David, E; Minehan, T; Orr, D; Shaktah, LA; Shaktah, R; Tamae, D; Vardanyan, L1
Abbrecht, PH; Penner, JA1
Levy, G; Slattery, JT1
Levy, G; Slattery, JT; Yacobi, A1
Tucker, GT1
Jenkins, BG; Lauffer, RB1
Pullar, T1
Henriksson, K; Schulman, S1
Royer, GL; Seckman, CE; Welshman, IR1
Furst, DE1
Aubry, AF; Rahim, S1
Nakasaka, T; Okabe, N1
Hashizume, N; Okabe, N1
Imai, T; Maruyama, T; Okada, T; Otagiri, M; Rahman, MH1
Bopp, BA; Kukulka, MJ; Machinist, JM1
Gabb, GM1
Haruta, A; Kodama, H; Otagiri, M; Suenaga, A; Takamura, N; Tsuruoka, M; Yamasaki, K1
Nerli, B; Picó, G; Romanini, D1
Kosa, T; Maruyama, T; Otagiri, M1
Kosa, T; Maruyama, T; Otagiri, M; Sakai, N; Yahara, S; Yonemura, N1
Ding, Y; Lin, B; Zhu, X1
Chen, X; Luo, Q; Ni, J; Wang, H; Zhang, Q; Zou, H1
Aime, S; Ascenzi, P; Baroni, S; Cipollone, R; Fasano, M; Mattu, M; Vannini, A1
Austin, J; Hage, DS; Kim, HS2
Tanaka, Y1
Brouwers, JR; de Jong-van den Berg, LT; de Vries-Bots, AM; Piersma-Wichers, M; Plat, AW; Slomp, J; van Dijk, AA; van Dijk, KN1
Dangles, O; Dufour, C1
Maftouh, M; Mangelings, D; Massart, DL; Matthijs, N; Tanret, I; Vander Heyden, Y1
Fielding, L; Fletcher, D; Rutherford, S1
Feng, R; Mandula, H; Parepally, JM; Smith, QR1
Fuentes Pradera, MA; Suárez Delgado, JM; Yanes Vidal, G; Yerga Pozo, G1
Hage, DS; Mallik, R1
Ascenzi, P; Fanali, G; Fasano, M1
Chordia, MD; Li, F; Macdonald, TL; Woodling, KA1
Hoshide, S; Kanou, M; Mukoyoshi, M; Muroga, H; Nishimura, S; Taniguchi, K; Umeda, S1
Glass, TA; Schwartz, JH; Sclafani, SJ; Sewell, PE1
Gao, S; Liu, SP; Xiong, ZY; Zhang, HX1
Peuravuori, J; Pihlaja, K1
Du, Y; Kou, J; Liu, X; Sun, W; Yu, B1
Huang, SD; Jiang, HD; Li, J; Sun, DL; Wu, PS; Ye, YJ1
Welling, A1
Briscoe, CJ; Hage, DS; Mallik, R; Yoo, MJ1
Marin, ML; Miranda, MA; Rohacova, J1
Ascenzi, P; Fasano, M1
Ito, S; Yamamoto, D1
Ascenzi, P; Cao, Y; Coletta, M; Fanali, G; Fasano, M; Tundo, GR1
Huang, ZX; Zhang, HX1
Kawai, T; Kitagawa, F; Koino, H; Otsuka, K; Sueyoshi, K1
Jensen, SE; Juel, J; Langfrits, CS; Pedersen, TB1
Kokot, S; Ni, Y; Zhang, F1
Arakawa, R; Iwaki, Y; Kawasaki, H1
Berka, K; Otyepka, M; Paloncýová, M1
Chen, D; Li, X; Lu, Y; Wang, G1
Bačić, GG; Mojović, MD; Pavićević, AA; Popović-Bijelić, AD; Šušnjar, SV1
Ascenzi, P; Bionducci, M; Colombo, G; Fanali, G; Fasano, M; Leboffe, L; Meli, M; Meneghini, C; Mobilio, S1
New, SY; Su, X; Tan, YN; Xie, J; Yu, Y1
Harrington, Pde B; Mao, Y; Qu, LB; Yang, R; Yu, L1
Li, X; Yang, Z1
Dey, J; Ghosh, S1
Cheng, F; Fadli, Z; Huang, H; Lu, Y; Nagar, C; Pietsch, M; Shen, D; Tu, YC1
Bykov, EE; Durandin, NA; Kaluzhny, DN; Lavrenov, SN; Preobrazhenskaya, MN; Tevyashova, AN; Tsvetkov, VB1
Han, J; Li, D; Liu, G; Liu, M; Wang, B; Wang, Z; Yuan, L; Zhang, M1
Pansare, AV; Patil, VR; Shedge, AA1
Derdau, V; Matter, H; Nazaré, M; Opatz, T; Petry, S; Schreuder, H; Volkmar, J; Wenskowsky, L1
Aguilar, MR; Arévalo, H; García-Fernández, L; Martín-Saldaña, S; Palao-Suay, R; Ramírez-Camacho, R; San Román, J; Trinidad, A1
Azam, MW; Khan, AU; Khan, SN; Maryam, L; Sharma, A1
Dahmardeh, S; Heidari Majd, M; Shahraki, S; Shiri, F1
Karimi, J; Khazalpour, S; Moghadam, NH; Saidijam, M; Salehzadeh, S; Tanzadehpanah, H1
Foster, DJR; Petito, ES; Sykes, MJ; Ward, MB1
Escher, BI; Fischer, FC; Henneberger, L; Mühlenbrink, M1
Matter, H; Opatz, T; Petry, SM; Reusch, J; Schreuder, H; Wagner, M; Wenskowsky, L1
Khaibrakhmanova, D; Nikiforova, A; Sedov, I1
Abdullah, KM; Al Jaseem, MAJ; Naseem, I; Qais, FA; Shamsi, A1
Kalhor, HR; Taghikhani, E1
Guan, Q; Wang, N; Wang, X; Yu, D; Zhang, G1
Bartucci, R; Guzzi, R1
Alexandri, E; Avgeropoulos, A; Gerothanassis, IP; Gkalpinos, VK; Karydis-Messinis, A; Moschovas, D; Papamokos, G; Primikyri, A; Tzakos, AG; Venianakis, T1
Granica, S; Korczak, M; Piwowarski, JP; Roszkowski, P1
Hamid, SJ; Salih, T1
Gerothanassis, IP; Kontogianni, VG; Papamokos, G; Primikyri, A; Sakka, M; Venianakis, T1
Al-Lohedan, HA; Al-Sanea, ASS; Ali, MS; Jain, M; Muthukumaran, J; Tariq, M1

Reviews

6 review(s) available for ibuprofen and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A clinical pharmacologist's perspective.
    Biochemical Society transactions, 1991, Volume: 19, Issue:2

    Topics: Animals; Humans; Ibuprofen; Pharmacokinetics; Propranolol; Stereoisomerism; Structure-Activity Relationship; Warfarin

1991
Method development of enantiomer separations by affinity capillary electrophoresis, cyclodextrin electrokinetic chromatography and capillary electrophoresis-mass spectrometry.
    Se pu = Chinese journal of chromatography, 2002, Volume: 20, Issue:4

    Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Electrophoresis, Capillary; Ibuprofen; Ketoprofen; Mass Spectrometry; Static Electricity; Stereoisomerism; Vanilmandelic Acid; Warfarin

2002
[Massive metrorrhagia in a patient under warfarin anticoagulation. Rapid reversal with a concentrated prothrombin complex (Prothromplex Immuno TIM 4 600 IU)].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:10

    Topics: Acetazolamide; Adult; Anticoagulants; Behcet Syndrome; Blood Coagulation Factors; Consciousness Disorders; Drug Synergism; Female; Glaucoma, Angle-Closure; Humans; Ibuprofen; International Normalized Ratio; Lupus Coagulation Inhibitor; Metrorrhagia; Thrombophilia; Warfarin

2006
Allostery in a monomeric protein: the case of human serum albumin.
    Biophysical chemistry, 2010, Volume: 148, Issue:1-3

    Topics: Allosteric Regulation; Animals; Binding Sites; Heme; Humans; Ibuprofen; Serum Albumin; Warfarin

2010
Molecular Modeling Approaches for the Prediction of Selected Pharmacokinetic Properties.
    Current topics in medicinal chemistry, 2018, Volume: 18, Issue:26

    Topics: Administration, Oral; Humans; Ibuprofen; Models, Molecular; Quantitative Structure-Activity Relationship; Serum Albumin, Human; Warfarin

2018

Trials

2 trial(s) available for ibuprofen and warfarin

ArticleYear
Lack of interaction between ibuprofen and warfarin.
    Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:6

    Topics: Adult; Blood Coagulation Tests; Clinical Trials as Topic; Drug Interactions; Humans; Ibuprofen; Male; Middle Aged; Phenylpropionates; Prothrombin Time; Thromboplastin; Time Factors; Warfarin

1975
Safety profile: fifteen years of clinical experience with ibuprofen.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Anti-Inflammatory Agents; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Proteins; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Eruptions; Drug Interactions; Drug Tolerance; Gastrointestinal Diseases; Humans; Ibuprofen; Kidney Diseases; Liver Function Tests; Warfarin

1984

Other Studies

102 other study(ies) available for ibuprofen and warfarin

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor.
    Bioorganic & medicinal chemistry letters, 2007, Aug-15, Volume: 17, Issue:16

    Topics: Albumins; Anti-Bacterial Agents; Binding Sites; Calorimetry; Fluorescence; Humans; ortho-Aminobenzoates; Protein Binding

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis and Stereochemical Assignment of Conioidine A: DNA- and HSA-Binding Studies of the Four Diastereomers.
    Journal of natural products, 2020, 10-23, Volume: 83, Issue:10

    Topics: Binding Sites; Binding, Competitive; Calorimetry; Circular Dichroism; DNA; Ethidium; Molecular Docking Simulation; Molecular Structure; Netropsin; Proline; Pyrrolidines; Serum Albumin, Human; Solanaceous Alkaloids; Spectrometry, Fluorescence; Stereoisomerism

2020
Effect of ibuprofen on protein binding of warfarin in human serum.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:7

    Topics: Binding Sites; Blood Proteins; Humans; Ibuprofen; Phenylpropionates; Protein Binding; Warfarin

1977
Comparative pharmacokinetics of coumarin anticoagulants XXV: Warfarin-ibuprofen interaction in rats.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:7

    Topics: Animals; Blood Coagulation; Blood Proteins; Half-Life; Ibuprofen; Kinetics; Male; Metabolic Clearance Rate; Phenylpropionates; Protein Binding; Rats; Time Factors; Warfarin

1977
Detection of site-specific binding and co-binding of ligands to human serum albumin using 19F NMR.
    Molecular pharmacology, 1990, Volume: 37, Issue:1

    Topics: Allosteric Regulation; Humans; Ibuprofen; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation; Serum Albumin; Tryptophan; Warfarin

1990
Interaction of ibuprofen and warfarin on primary haemostasis.
    British journal of rheumatology, 1989, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aged; Bleeding Time; Drug Interactions; Hemostasis; Humans; Ibuprofen; Warfarin

1989
Interaction of ibuprofen and warfarin on primary haemostasis.
    British journal of rheumatology, 1989, Volume: 28, Issue:1

    Topics: Aged; Bleeding Time; Drug Interactions; Female; Hemostasis; Humans; Ibuprofen; Male; Middle Aged; Platelet Count; Rheumatic Diseases; Warfarin

1989
Use of ibuprofen in unusual circumstances.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersensitivity; Drug Interactions; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Kidney; Kinetics; Lithium; Liver; Lupus Erythematosus, Systemic; Mixed Connective Tissue Disease; Phenytoin; Platelet Aggregation; Prostaglandins E; Warfarin

1984
Location of binding sites on immobilized human serum albumin for some nonsteroidal anti-inflammatory drugs.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin; Warfarin

1995
Drug binding properties of glycosylated bovine serum albumin as measured by circular dichroism.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:11

    Topics: Binding Sites; Circular Dichroism; Flufenamic Acid; Glycosylation; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin, Bovine; Warfarin

1994
Drug binding properties of glycosylated human serum albumin as measured by fluorescence and circular dichroism.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1

    Topics: Binding Sites; Circular Dichroism; Dansyl Compounds; Flufenamic Acid; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Ibuprofen; Phenylbutazone; Proline; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin

1994
Study of interaction of carprofen and its enantiomers with human serum albumin--II. Stereoselective site-to-site displacement of carprofen by ibuprofen.
    Biochemical pharmacology, 1993, Nov-17, Volume: 46, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Carbazoles; Circular Dichroism; Dialysis; Humans; Ibuprofen; Mathematics; Models, Chemical; Phenylbutazone; Serum Albumin; Stereoisomerism; Warfarin

1993
In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.
    Clinical pharmacokinetics, 1995, Volume: 29 Suppl 2

    Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Anticoagulants; Blood Proteins; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hematocrit; Humans; Hydroxylation; Hydroxyurea; Ibuprofen; In Vitro Techniques; Isotope Labeling; Lipoxygenase Inhibitors; Male; Naproxen; Prednisolone; Protein Binding; Salicylates; Stereoisomerism; Terfenadine; Theophylline; Warfarin

1995
Fatal outcome of interaction between warfarin and a non-steroidal anti-inflammatory drug.
    The Medical journal of Australia, 1996, Jun-03, Volume: 164, Issue:11

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Interactions; Fatal Outcome; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Warfarin

1996
Mode of interaction of loop diuretics with human serum albumin and characterization of binding site.
    Pharmaceutical research, 1996, Volume: 13, Issue:7

    Topics: Binding Sites; Diuretics; Fluorescent Dyes; Furosemide; Humans; Ibuprofen; Lysine; Protein Binding; Serum Albumin; Sulfonamides; Warfarin

1996
Structural specificity requirements in the binding of beta lactam antibiotics to human serum albumin.
    Chemico-biological interactions, 1997, May-02, Volume: 104, Issue:2-3

    Topics: Acid-Base Equilibrium; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Binding Sites; Binding, Competitive; Cephalosporins; Coumarins; Esterases; Fatty Acids; Glycosylation; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indicators and Reagents; Kinetics; Ligands; Lysine; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Ultrafiltration

1997
Species differences of serum albumins: I. Drug binding sites.
    Pharmaceutical research, 1997, Volume: 14, Issue:11

    Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Humans; Ibuprofen; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Rabbits; Rats; Serum Albumin; Warfarin

1997
Species differences of serum albumins: III. Analysis of structural characteristics and ligand binding properties during N-B transitions.
    Pharmaceutical research, 1998, Volume: 15, Issue:4

    Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ligands; Phenylbutazone; Protein Conformation; Rabbits; Rats; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Warfarin

1998
Study of interaction between drug enantiomers and serum albumin by capillary electrophoresis.
    Electrophoresis, 1999, Volume: 20, Issue:9

    Topics: Binding, Competitive; Bupivacaine; Electrophoresis, Capillary; Ibuprofen; Isomerism; Protein Binding; Serum Albumin; Verapamil; Warfarin

1999
Synthesis and characteristics of the human serum albumin-triazine chiral stationary phase.
    Chirality, 2000, Volume: 12, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Atropine; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fenoprofen; Glutamic Acid; Humans; Ibuprofen; Naproxen; Protein Binding; Serum Albumin; Silicon Dioxide; Spectrophotometry, Ultraviolet; Stereoisomerism; Triazines; Tryptophan; Warfarin

2000
Effect of ibuprofen and warfarin on the allosteric properties of haem-human serum albumin. A spectroscopic study.
    European journal of biochemistry, 2001, Volume: 268, Issue:23

    Topics: Allosteric Site; Binding Sites; Electron Spin Resonance Spectroscopy; Heme; Humans; Ibuprofen; In Vitro Techniques; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Binding; Protein Conformation; Serum Albumin; Spectrophotometry; Warfarin

2001
Identification of drug-binding sites on human serum albumin using affinity capillary electrophoresis and chemically modified proteins as buffer additives.
    Electrophoresis, 2002, Volume: 23, Issue:6

    Topics: 2-Hydroxy-5-nitrobenzyl Bromide; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Buffers; Chemical Warfare Agents; Dextrans; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Molecular Structure; Serum Albumin; Suprofen; Tetranitromethane; Tryptophan; Warfarin

2002
Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype.
    Thrombosis and haemostasis, 2004, Volume: 91, Issue:1

    Topics: Acenocoumarol; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Chi-Square Distribution; Cohort Studies; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Female; Genotype; Humans; Ibuprofen; International Normalized Ratio; Male; Middle Aged; Naproxen; Retrospective Studies; Sex Factors; Time Factors; Warfarin

2004
Screening major binding sites on human serum albumin by affinity capillary electrophoresis.
    Methods in molecular biology (Clifton, N.J.), 2004, Volume: 276

    Topics: 2-Hydroxy-5-nitrobenzyl Bromide; Apazone; Benzodiazepines; Electrophoresis, Capillary; Humans; Ibuprofen; Indoles; Protein Binding; Serum Albumin; Tetranitromethane; Tryptophan; Warfarin

2004
Flavonoid-serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy.
    Biochimica et biophysica acta, 2005, Jan-18, Volume: 1721, Issue:1-3

    Topics: Binding Sites; Flavonoids; Humans; Ibuprofen; Protein Binding; Quercetin; Serum Albumin; Spectrometry, Fluorescence; Warfarin

2005
Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases.
    Electrophoresis, 2005, Volume: 26, Issue:4-5

    Topics: Acetonitriles; Buffers; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Hexobarbital; Hydrogen-Ion Concentration; Ibuprofen; Pharmaceutical Preparations; Polysaccharides; Stereoisomerism; Temperature; Warfarin

2005
Determination of protein-ligand binding affinity by NMR: observations from serum albumin model systems.
    Magnetic resonance in chemistry : MRC, 2005, Volume: 43, Issue:6

    Topics: Animals; Calorimetry; Cattle; Ibuprofen; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Naproxen; Protein Binding; Proteins; Salicylates; Serum Albumin; Tryptophan; Warfarin

2005
Role of site-specific binding to plasma albumin in drug availability to brain.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:2

    Topics: Animals; Binding, Competitive; Biological Availability; Brain; Ibuprofen; Male; Perfusion; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Serum Albumin; Tolbutamide; Ultrafiltration; Valproic Acid; Warfarin

2006
Development of an affinity silica monolith containing human serum albumin for chiral separations.
    Journal of pharmaceutical and biomedical analysis, 2008, Apr-14, Volume: 46, Issue:5

    Topics: Chromatography, Affinity; Humans; Ibuprofen; Methylmethacrylates; Models, Chemical; Particle Size; Permeability; Pressure; Reproducibility of Results; Schiff Bases; Serum Albumin; Silicon Dioxide; Stereoisomerism; Surface Properties; Technology, Pharmaceutical; Tryptophan; Warfarin

2008
Effect of prototypic drugs ibuprofen and warfarin on global chaotropic unfolding of human serum heme-albumin: a fast-field-cycling 1H-NMR relaxometric study.
    Biophysical chemistry, 2007, Volume: 129, Issue:1

    Topics: Humans; Ibuprofen; Magnetic Resonance Spectroscopy; Methemalbumin; Protein Conformation; Protein Denaturation; Protein Folding; Thermodynamics; Warfarin

2007
Irreversible alkylation of human serum albumin by zileuton metabolite 2-acetylbenzothiophene-S-oxide: a potential model for hepatotoxicity.
    Chemical research in toxicology, 2007, Volume: 20, Issue:12

    Topics: Alkylation; Anti-Asthmatic Agents; Binding, Competitive; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Half-Life; Humans; Hydroxyurea; Ibuprofen; Models, Biological; Serum Albumin; Tandem Mass Spectrometry; Thiophenes; Warfarin

2007
In vitro drug-drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:5

    Topics: Blood Proteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Febuxostat; Glucuronosyltransferase; Humans; Ibuprofen; In Vitro Techniques; Male; Microsomes, Liver; Protein Binding; Thiazoles; Warfarin; Xanthine Oxidase

2008
Acute gonadal vein thrombosis secondary to terminal ileitis and thrombophilia.
    The Journal of urology, 2008, Volume: 180, Issue:3

    Topics: Acute Disease; Adult; Diagnosis, Differential; Fluid Therapy; Humans; Ibuprofen; Ileitis; Ketorolac Tromethamine; Male; Platelet Aggregation Inhibitors; Pressure; Testis; Thrombophilia; Thrombosis; Tomography, X-Ray Computed; Warfarin

2008
Fluorometric probing on the binding of hematoxylin to serum albumin.
    Molecular biology reports, 2009, Volume: 36, Issue:8

    Topics: Hematoxylin; Ibuprofen; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Thermodynamics; Warfarin

2009
Phototransformations of selected pharmaceuticals under low-energy UVA-vis and powerful UVB-UVA irradiations in aqueous solutions--the role of natural dissolved organic chromophoric material.
    Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:6

    Topics: Carbamazepine; Ibuprofen; Kinetics; Metoprolol; Molecular Structure; Molecular Weight; Nitrates; Photochemical Processes; Solid Phase Extraction; Solubility; Solutions; Ultraviolet Rays; Warfarin

2009
Study on the interaction of levocetirizine dihydrochloride with human serum albumin by molecular spectroscopy.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Volume: 74, Issue:5

    Topics: Binding Sites; Calcium; Cetirizine; Circular Dichroism; Dansyl Compounds; Glycosylation; Humans; Ibuprofen; Ions; Kinetics; Metals; Proline; Protein Structure, Secondary; Serum Albumin; Spectrometry, Fluorescence; Temperature; Warfarin

2009
Stereoselective protein binding of tetrahydropalmatine enantiomers in human plasma, HSA, and AGP, but not in rat plasma.
    Chirality, 2010, Volume: 22, Issue:6

    Topics: Animals; Berberine Alkaloids; Binding, Competitive; Drug Interactions; Humans; Ibuprofen; Imipramine; Male; Mifepristone; Orosomucoid; Plasma; Protein Binding; Rats; Rats, Sprague-Dawley; Serum Albumin; Stereoisomerism; Substrate Specificity; Warfarin

2010
Ibuprofen and warfarin.
    Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 2009, Volume: 17, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Cellulitis; Drug Interactions; Emergency Treatment; Humans; Ibuprofen; Insect Bites and Stings; Warfarin

2009
Analysis of drug-protein binding by ultrafast affinity chromatography using immobilized human serum albumin.
    Journal of chromatography. A, 2010, Apr-23, Volume: 1217, Issue:17

    Topics: Chromatography, Affinity; Humans; Ibuprofen; Imipramine; Immobilized Proteins; Kinetics; Protein Binding; Serum Albumin; Warfarin

2010
Complexes between fluorescent cholic acid derivatives and human serum albumin. a photophysical approach to investigate the binding behavior.
    The journal of physical chemistry. B, 2010, Apr-08, Volume: 114, Issue:13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Binding Sites; Cholic Acid; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Ibuprofen; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin

2010
Identification of two bromocresol purple binding sites on human serum albumin.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Oct-09, Volume: 411, Issue:19-20

    Topics: Binding Sites; Bromcresol Purple; Humans; Hydrogen-Ion Concentration; Ibuprofen; Myristic Acid; Propofol; Serum Albumin; Warfarin

2010
Ibuprofen and warfarin modulate allosterically ferrous human serum heme-albumin nitrosylation.
    Biochemical and biophysical research communications, 2011, Jul-22, Volume: 411, Issue:1

    Topics: Allosteric Regulation; Anti-Inflammatory Agents, Non-Steroidal; Heme; Humans; Ibuprofen; Nitric Oxide; Protein Conformation; Serum Albumin; Warfarin

2011
Biochemical evaluation of a synthesized isoflavone-selenium complex by molecular spectra.
    Molecular biology reports, 2012, Volume: 39, Issue:7

    Topics: Albumins; Animals; Binding Sites; Cattle; Ibuprofen; Isoflavones; Organoselenium Compounds; Protein Binding; Selenium Compounds; Serum Albumin, Bovine; Thermodynamics; Warfarin

2012
Highly sensitive chiral analysis in capillary electrophoresis with large-volume sample stacking with an electroosmotic flow pump.
    Journal of chromatography. A, 2012, Jul-13, Volume: 1246

    Topics: Abscisic Acid; Amino Acids; beta-Cyclodextrins; Electroosmosis; Electrophoresis, Capillary; Humans; Ibuprofen; Limit of Detection; Male; Models, Chemical; Reproducibility of Results; Stereoisomerism; Warfarin

2012
Administration of tramadol or ibuprofen increases the INR level in patients on warfarin.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:2

    Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Atrial Fibrillation; Back Pain; Drug Interactions; Humans; Ibuprofen; International Normalized Ratio; Male; Tramadol; Warfarin

2013
Enantioselective binding interaction of the metolachlor pesticide enatiomers with bovine serum albumin--a spectroscopic analysis study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 97

    Topics: Absorption; Acetamides; Animals; Binding Sites; Binding, Competitive; Cattle; Ibuprofen; Kinetics; Least-Squares Analysis; Multivariate Analysis; Pesticides; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Thermodynamics; Warfarin

2012
Human serum albumin-modified Fe3O4 magnetic nanoparticles for affinity-SALDI-MS of small-molecule drugs in biological liquids.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2012, Volume: 28, Issue:9

    Topics: Camptothecin; Ferrosoferric Oxide; Humans; Ibuprofen; Magnetite Nanoparticles; Molecular Weight; Phenytoin; Sensitivity and Specificity; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Warfarin

2012
Molecular insight into affinities of drugs and their metabolites to lipid bilayers.
    The journal of physical chemistry. B, 2013, Feb-28, Volume: 117, Issue:8

    Topics: Caffeine; Cell Membrane; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Ibuprofen; Lipid Bilayers; Molecular Dynamics Simulation; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics; Xenobiotics

2013
Binding of ascorbic acid and α-tocopherol to bovine serum albumin: a comparative study.
    Molecular bioSystems, 2014, Volume: 10, Issue:2

    Topics: Adsorption; alpha-Tocopherol; Ascorbic Acid; Binding Sites; Calorimetry; Entropy; Hydrogen Bonding; Ibuprofen; Protein Binding; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Tryptophan; Tyrosine; Warfarin

2014
Binding of doxyl stearic spin labels to human serum albumin: an EPR study.
    The journal of physical chemistry. B, 2014, Sep-18, Volume: 118, Issue:37

    Topics: Ascorbic Acid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Humans; Ibuprofen; Protein Binding; Serum Albumin; Spin Labels; Temperature; Warfarin

2014
The five-to-six-coordination transition of ferric human serum heme-albumin is allosterically-modulated by ibuprofen and warfarin: a combined XAS and MD study.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Absorptiometry, Photon; Allosteric Regulation; Heme; Humans; Ibuprofen; Iron; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Serum Albumin; Warfarin

2014
Protein-based fluorescent metal nanoclusters for small molecular drug screening.
    Chemical communications (Cambridge, England), 2014, Nov-18, Volume: 50, Issue:89

    Topics: Drug Evaluation, Preclinical; Fluorescent Dyes; Gold; Ibuprofen; Nanostructures; Phenytoin; Serum Albumin; Sulfanilamide; Sulfanilamides; Warfarin

2014
A novel method for the study of molecular interaction by using microscale thermophoresis.
    Talanta, 2015, Volume: 132

    Topics: Animals; Binding, Competitive; Cattle; Fluorescein-5-isothiocyanate; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Kinetics; Models, Molecular; Motion; Protein Aggregates; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Thermodynamics; Warfarin

2015
Interaction of oridonin with human serum albumin by isothermal titration calorimetry and spectroscopic techniques.
    Chemico-biological interactions, 2015, May-05, Volume: 232

    Topics: Binding Sites; Calorimetry; Diterpenes, Kaurane; Humans; Hydrogen Bonding; Ibuprofen; Serum Albumin; Spectrometry, Fluorescence; Warfarin

2015
Binding of Fatty Acid Amide Amphiphiles to Bovine Serum Albumin: Role of Amide Hydrogen Bonding.
    The journal of physical chemistry. B, 2015, Jun-25, Volume: 119, Issue:25

    Topics: Amides; Calorimetry; Circular Dichroism; Fatty Acids; Hydrogen Bonding; Ibuprofen; Micelles; Microscopy, Fluorescence; Models, Molecular; Molecular Structure; Protein Conformation; Sarcosine; Serum Albumin, Bovine; Spectrum Analysis; Surface Tension; Surface-Active Agents; Thermodynamics; Warfarin

2015
A novel algorithm for analyzing drug-drug interactions from MEDLINE literature.
    Scientific reports, 2015, Nov-27, Volume: 5

    Topics: Algorithms; Contraindications; Drug Interactions; Enzymes; Furosemide; Humans; Hydrolysis; Ibuprofen; MEDLINE; Sertraline; Warfarin

2015
Quantitative parameters of complexes of tris(1-alkylindol-3-yl)methylium salts with serum albumin: Relevance for the design of drug candidates.
    Journal of photochemistry and photobiology. B, Biology, 2016, Volume: 162

    Topics: Binding Sites; Circular Dichroism; Humans; Ibuprofen; Indoles; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Salts; Serum Albumin; Spectrometry, Fluorescence; Thermodynamics; Warfarin

2016
Competitive binding of (-)-epigallocatechin-3-gallate and 5-fluorouracil to human serum albumin: A fluorescence and circular dichroism study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2017, Feb-15, Volume: 173

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Binding Sites; Binding, Competitive; Catechin; Circular Dichroism; Drug Synergism; Fluorouracil; Humans; Ibuprofen; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Warfarin

2017
Discrete SeNPs-Macromolecule Binding Manipulated by Hydrophilic Interaction.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt B

    Topics: Animals; Calorimetry, Differential Scanning; Cattle; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Macromolecular Substances; Nanoparticles; Selenium; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Warfarin

2018
Identification and Characterization of a Single High-Affinity Fatty Acid Binding Site in Human Serum Albumin.
    Angewandte Chemie (International ed. in English), 2018, 01-22, Volume: 57, Issue:4

    Topics: Azoles; Binding Sites; Crystallography, X-Ray; Fatty Acids; Fluorescence Resonance Energy Transfer; Humans; Ibuprofen; Molecular Dynamics Simulation; Nitrobenzenes; Protein Binding; Protein Domains; Serum Albumin, Human; Warfarin

2018
pH-sensitive polymeric nanoparticles with antioxidant and anti-inflammatory properties against cisplatin-induced hearing loss.
    Journal of controlled release : official journal of the Controlled Release Society, 2018, 01-28, Volume: 270

    Topics: alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cisplatin; Coumarins; Dexamethasone; Hearing Loss; Hydrogen-Ion Concentration; Ibuprofen; Nanoparticles; Polymers; Rats, Wistar; Thiazoles

2018
Understanding the mode of binding mechanism of doripenem to human serum albumin: Spectroscopic and molecular docking approaches.
    Journal of molecular recognition : JMR, 2018, Volume: 31, Issue:7

    Topics: Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Diazepam; Doripenem; Humans; Hydrogen Bonding; Ibuprofen; Indomethacin; Kinetics; Molecular Docking Simulation; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Serum Albumin, Human; Solutions; Static Electricity; Temperature; Thermodynamics; Warfarin

2018
Anti-cancer study and whey protein complexation of new lanthanum(III) complex with the aim of achieving bioactive anticancer metal-based drugs.
    Journal of biomolecular structure & dynamics, 2019, Volume: 37, Issue:8

    Topics: Animals; Antineoplastic Agents; Binding Sites; Carrier Proteins; Cattle; Cell Death; Computer Simulation; Fluorescence Resonance Energy Transfer; Humans; Hydrogen-Ion Concentration; Ibuprofen; Lactoglobulins; Lanthanum; MCF-7 Cells; Molecular Conformation; Molecular Docking Simulation; Protein Structure, Secondary; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Warfarin; Whey Proteins

2019
In vitro cytotoxicity and DNA/HSA interaction study of triamterene using molecular modelling and multi-spectroscopic methods.
    Journal of biomolecular structure & dynamics, 2019, Volume: 37, Issue:9

    Topics: Animals; Antineoplastic Agents; Binding, Competitive; Cell Line, Tumor; Cell Survival; DNA; HCT116 Cells; Humans; Ibuprofen; Mice; Molecular Docking Simulation; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Triamterene; Warfarin

2019
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
    Chemical research in toxicology, 2019, 01-22, Volume: 32, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cattle; Cells, Cultured; Diclofenac; Genistein; HEK293 Cells; Humans; Ibuprofen; Kinetics; Liposomes; Naproxen; Phospholipids; Serum Albumin, Bovine; Solid Phase Microextraction; Torsemide; Warfarin

2019
Resolving Binding Events on the Multifunctional Human Serum Albumin.
    ChemMedChem, 2020, 05-06, Volume: 15, Issue:9

    Topics: 4-Chloro-7-nitrobenzofurazan; Binding Sites; Boron Compounds; Crystallography, X-Ray; Fluorescence; Humans; Ibuprofen; Lauric Acids; Molecular Dynamics Simulation; Molecular Structure; Serum Albumin, Human; Warfarin

2020
Evaluation of the binding properties of drugs to albumin from DSC thermograms.
    International journal of pharmaceutics, 2020, Jun-15, Volume: 583

    Topics: Calorimetry, Differential Scanning; Ibuprofen; Isoniazid; Naproxen; Protein Binding; Serum Albumin, Bovine; Warfarin

2020
Mechanistic insight into glycation inhibition of human serum albumin by vitamin B9: Multispectroscopic and molecular docking approach.
    International journal of biological macromolecules, 2021, Jun-30, Volume: 181

    Topics: Binding Sites; Circular Dichroism; Folic Acid; Glycation End Products, Advanced; Glycosylation; Humans; Ibuprofen; Lysine; Molecular Docking Simulation; Osmolar Concentration; Protein Carbonylation; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence; Spectrum Analysis; Sulfhydryl Compounds; Thermodynamics; Warfarin

2021
Probe into the Molecular Mechanism of Ibuprofen Interaction with Warfarin Bound to Human Serum Albumin in Comparison to Ascorbic and Salicylic Acids: Allosteric Inhibition of Anticoagulant Release.
    Journal of chemical information and modeling, 2021, 08-23, Volume: 61, Issue:8

    Topics: Anticoagulants; Binding Sites; Humans; Ibuprofen; Molecular Docking Simulation; Protein Binding; Salicylates; Serum Albumin; Serum Albumin, Human; Warfarin

2021
The interaction of folate-modified Bletilla striata polysaccharide-based micelle with bovine serum albumin.
    Glycoconjugate journal, 2021, Volume: 38, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Anticoagulants; Cell Line, Tumor; Doxorubicin; Folic Acid; Ibuprofen; Mice; Micelles; Models, Molecular; Polysaccharides; Protein Binding; Protein Conformation; Protein Domains; Serum Albumin, Bovine; Warfarin

2021
Interactive multiple binding of oleic acid, warfarin and ibuprofen with human serum albumin revealed by thermal and fluorescence studies.
    European biophysics journal : EBJ, 2022, Volume: 51, Issue:1

    Topics: Binding Sites; Humans; Ibuprofen; Oleic Acid; Protein Binding; Serum Albumin, Human; Warfarin

2022
NMR and computational studies reveal novel aspects in molecular recognition of unsaturated fatty acids with non-labelled serum albumin.
    The FEBS journal, 2022, Volume: 289, Issue:18

    Topics: alpha-Linolenic Acid; Amino Acids; Binding Sites; Fatty Acids; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Ibuprofen; Ligands; Linoleic Acids; Magnetic Resonance Spectroscopy; Oleic Acids; Protein Binding; Serum Albumin; Warfarin

2022
Conjugates of urolithin A with NSAIDs, their stability, cytotoxicity, and anti-inflammatory potential.
    Scientific reports, 2022, 07-08, Volume: 12, Issue:1

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Coumarins; Humans; Ibuprofen

2022
Design, Synthesis, and Anti-Inflammatory Activity of Some Coumarin Schiff Base Derivatives: In silico and in vitro Study.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Coumarins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Inflammation; Ligands; Molecular Docking Simulation; Schiff Bases

2022
Structural Basis of Artemisinin Binding Sites in Serum Albumin with the Combined Use of NMR and Docking Calculations.
    Molecules (Basel, Switzerland), 2022, Sep-12, Volume: 27, Issue:18

    Topics: Artemisinins; Binding Sites; Biological Products; Complex Mixtures; Humans; Ibuprofen; Ligands; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human; Warfarin

2022
Detailed Experimental and In Silico Investigation of Indomethacin Binding with Human Serum Albumin Considering Primary and Secondary Binding Sites.
    Molecules (Basel, Switzerland), 2023, Mar-27, Volume: 28, Issue:7

    Topics: Binding Sites; Circular Dichroism; Hemin; Humans; Ibuprofen; Indomethacin; Molecular Docking Simulation; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Warfarin

2023