Compounds > ibuprofen

ibuprofen and thromboxane b2

ibuprofen has been researched along with thromboxane b2 in 113 studies

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-199059 (52.21)18.7374
1990's33 (29.20)18.2507
2000's18 (15.93)29.6817
2010's3 (2.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N1
Coran, AG; Drongowski, RA; Paik, JJ; Remick, DG1
Simmet, T; Tschorn, K; Weide, I1
Byrick, RJ; Mullen, JB; Wigglesworth, DF; Wong, PY1
Bernard, GR; Hardie, WD; Swindell, BB; Wheeler, AP; Wright, PW1
Goldhaber, P; Hall, CM; Howell, TH; Jeffcoat, MK; Johnson, HG; Odle, BM; Offenbacher, S; Smith, MA; Williams, RC1
Flynn, JF; Gore, DC; Griffin, MP; Herndon, DN; Lobe, TE; Traber, DL1
Arosio, E; Degan, M; Lechi, A; Minuz, P; Pancera, P; Priante, F; Ribul, M1
Fink, MP; Kaups, KL; Rothschild, HR; Wang, H1
Cashman, SJ; Dollery, CT; Fuller, RW; Rees, AJ; Ritter, JM; Ward, PS1
Hudson, JC; Kane, FR; Mackey, WC; O'Donnel, TF; Su, YF; Watkins, WD; Wurm, WH1
Carlson, RW; Schneidkraut, MJ2
Klassen, DK; Spilman, PS; Stout, RL; Whelton, A1
Aranda, JV; Beharry, K; Chemtob, S; Rex, J; Varma, DR1
García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M1
Gerok, W; Häussinger, D; vom Dahl, S; Wettstein, M1
Demling, RH; Hechtman, H; Jin, LJ; Lalonde, C; West, K; Wong, C1
Lapointe, DS; Olson, MS1
Danilowicz, M; Eling, TE; Luster, MI; Tucker, AN; Vore, SJ1
Cohn, SM; Deniz, YF; Fink, MP; Lee, PC; Rothschild, HR; Wang, HL1
Satriano, JA; Schlondorff, D1
Biaggioni, I; Enayat, N; King, LS; Newman, JH; Robertson, D1
Hechtman, HB; Klausner, JM; Kobzik, L; Paterson, IS; Rodzen, C; Shepro, D; Valeri, CR1
Chyatte, D1
Bernard, GR; Wright, PE1
Jung, TT1
Andresen, PJ; Chacho, KJ; Chacho, MS; Scommegna, A1
Barsacchi, R; De Caterina, R; Giannessi, D; Lazzerini, G; Nanni, N; Pelosi, G1
Johnson, A; Malik, AB; Perlman, MB1
Daskalopoulos, G; Gentilini, P; Hsueh, W; Kronborg, I; Laffi, G; Zipser, RD1
Hirsch, JI; Hirsh, PD; Lee, CC; Sugerman, HJ; Tatum, JL; Wright, TP1
Brigham, KL; Ogletree, ML; Snapper, JR1
Bjornson, AB; Bjornson, HS; Knippenberg, RW1
Brune, K; Reinke, M1
Hechtman, DH; Jageneau, A1
Bruck, DC; Lemen, RJ; Magarelli, JL; Quan, SF; Sobonya, RE; Witten, ML1
Wang, ZG; Zhou, BT; Zhou, YG1
Breslow, MJ; Miller, CF; Nishijima, MK; Traystman, RJ1
Kelley, VE; Musinski, S; Sneve, S1
Demling, R; Katz, A; Lalonde, C; Ryan, P; West, K1
Entman, ML; Hunt, JR; Lewis, RM; Michael, LH1
Burke, J; Hales, C; Jung, W; Shinozawa, Y1
Jalovaara, P; Kairaluoma, M; Kiviniemi, H; Laitinen, S; Rämö, J; Ståhlberg, M; Viinikka, L1
Blocher, CR; Harvey, CF; Lee, EC; Sielaff, TD; Sugerman, HJ; Tatum, JL1
Anner, H; Hechtman, HB; Kaufman, RP; Kobzik, L; Shepro, D; Valeri, CR1
Demling, RH; Lalonde, C1
Fink, MP; Nelson, R; Roethel, R1
Cook, JA; Halushka, PV; Knapp, RG; Wise, WC1
Demling, RH; Hechtman, H; Wenger, H; Wong, C1
Bellanti, JA; Cerquetti, MC; el-Tawil, G; Hooke, AM; Ramwell, PW; Sordelli, DO1
Bruss, ML; Emau, P; Giri, SN; Zia, S1
Beyers, BJ; Bowen, RJ; Longenecker, GL; Shah, AK; Swift, IA1
Demling, RH; Wenger, H; Wong, C1
Alexander, F; Hechtman, HB; Kobzik, L; Lelcuk, S; Shepro, D; Valeri, CR1
Farias, LR; Frey, CF; Gunther, R; Holcroft, JW1
Bombardieri, S; Ciabattoni, G; Cinotti, GA; Di Munno, O; Gotti, E; Patrono, C; Pierucci, A; Remuzzi, G; Simonetti, BM; Tartarelli, G1
Johnson, A; Malik, AB1
Dauber, JH; Rinaldo, JE1
Coleman, JH; Greenblatt, DJ; Jones, KJ; Levine, PH; Orsulak, PJ; Peterson, M; Schildkraut, JJ; Sheehan, DV; Uzogara, E; Watkins, D1
Butler, RR; Cook, JA; Halushka, PV; Wise, WC1
Hill, RD; Hüttemeier, PC; Kong, D; Schuette, AH; Watkins, WD; Wonders, TR; Zapol, WM1
Brigham, KL; Hutchison, AA; Ogletree, ML; Snapper, JR1
Burke, SE; Lefer, AM; Roth, DM1
Ehrlich, HP1
Andres, GA; Dunn, MJ; Lianos, EA1
Ambrose, T; Carey, LC; Cloutier, CT; Kopolovic, R; Martin, DT; Thrailkill, KM; Vento, M1
Dunham, B; Hechtman, HB; Krausz, MM; Levine, L; Shepro, D; Utsunomiya, T; Valeri, CR1
Hill, RD; Landa, L; Lowenstein, E; Michelassi, F; Petkau, AJ; Watkins, WD; Zapol, WM1
Halushka, PV; Izui, S; Kelley, VE1
Lefer, AM; Smith, JB; Walinsky, P; Wiener, L1
Czervionke, RL; Hoak, JC; Parks, WM1
Dunham, B; Hechtman, HB; Krausz, MM; Levine, LL; Shepro, D; Utsunomiya, T1
Coppo, PA; Hammerschmidt, DE; Jacob, HS; Xiu, RJ1
Crossley, K; Lefer, AM1
Cook, JA; Eller, T; Halushka, PV; Wise, WC1
Heckenberger, R; Palmér, M; Schrör, K; Strobach, H; Villanueva, M1
Kroegel, C; Matthys, H1
Collins, JN; Fletcher, JR; Graves, ED; Izenberg, SD; Luterman, A; Rodning, CB; Williams, MD1
Arosio, E; Lechi, A; Minuz, P; Pancera, P; Pirante, F; Ribul, M1
Frölich, JC; Gutzki, FM; Stichtenoth, DO; Tsikas, D1
Cook, ME; Garcia, MM; Kadowitz, PJ; Lipani, JA; McNamara, DB; Poland, M; Thakur, VD; Wallin, JD1
Brinkmann, A; Brückner, U; Büchler, M; Georgieff, M; Kneitinger, E; Radermacher, P; Rockemann, M; Seeling, W; Vogeser, F; Wolf, CF1
Brugger, R; Brune, K; Euchenhofer, C; Geisslinger, G; Neupert, W1
Häussinger, D; Wettstein, M1
De Lepeleire, I; De Schepper, PJ; Depré, M; Larson, P; Lin, C; Porras, A; Schwartz, J; Van Hecken, A; Verbesselt, R1
Brinkmann, A; Büchler, M; Georgieff, M; Kneitinger, E; Orend, KH; Radermacher, P; Schönberger, C; Seeling, W; Vogt, N; Wolf, CF1
Catella-Lawson, F; FitzGerald, GA; Kapoor, S; Lawson, JA; Mardini, IA; McAdam, BF1
Dirig, DM; Yaksh, TL1
Arons, MM; Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, W; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, P1
Heidemann, SM; Ofenstein, JP; Sarnaik, AP1
Cook, ME; Thakur, V; Wallin, JD1
Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E1
Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K1
Ciabattoni, G; Collura, M; Davì, G; Ganci, A; Iapichino, L; Maclouf, J; Pardo, F; Patrono, C; Romagnoli, R1
Catella-Lawson, F; Cucchiara, AJ; DeMarco, S; FitzGerald, GA; Kapoor, SC; Reilly, MP; Tournier, B; Vyas, SN1
Brahim, JS; Dionne, RA; Khan, AA; Rowan, JS1
Brockmöller, J; Freytag, G; Kirchheiner, J; Meineke, I; Meisel, C; Roots, I1
Akbulut, A; Canbaz, M; Celik, I; Felek, S; Kilic, SS; Rahman, A; Vural, P1
Kent, JD; Leese, PT; Recker, DP1
Berlin, RG; Cooper, SA; Cryer, B; Hsu, C; Wason, S1
Barnes, PJ; Ciabattoni, G; Ciappi, G; Kharitonov, SA; Lauriola, L; Macagno, F; Montuschi, P; Parente, P; Valente, S1
Capone, ML; D'Amelio, E; De Caterina, R; Grana, M; Patrignani, P; Patrono, C; Price, TS; Renda, G; Sacchetta, D; Santarelli, F; Sciulli, MG; Tacconelli, S; Zimarino, M; Zurro, M1
Flipo, RM1
Hashiguchi, Y; Ishiguro, S; Miyamoto, A; Nishio, A; Obi, T1
Heinisch, B; Joukhadar, C; Kaehler, S; Kazemi-Shirazi, L; Marsik, C; Sauermann, R; Thallinger, C; Wagner, O1
Abad-Santos, M; Abad-Santos, P; Aranda, JV; Beharry, KD; Gharraee, Z; Hasan, J; Modanlou, HD; Stavitsky, Y1
Kankaanranta, H; Kerola, M; Kosonen, O; Moilanen, E; Sarna, S; Vuolteenaho, K1
de Metz, M; Huntjens-Fleuren, HW; Schuijt, MP; Vollaard, EJ1
De la Cruz, JP; Gonzalez-Correa, JA; Jebrouni, N; Lopez-Villodres, JA; Reyes, JJ; Ruiz-Moreno, MI1
Akagi, Y; Aoyama, T; Nio, Y; Shimada, S1
Aranda, JV; Beharry, KD; Cai, CL; Lazzaro, D; Salomone, F; Valencia, AM; Valencia, GB1

Reviews

1 review(s) available for ibuprofen and thromboxane b2

ArticleYear
[Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:9 Spec No

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cyclooxygenase Inhibitors; Drug Interactions; Follow-Up Studies; Humans; Ibuprofen; MEDLINE; Middle Aged; Multivariate Analysis; Naproxen; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Thromboxane B2; Ticlopidine; Time Factors

2006

Trials

25 trial(s) available for ibuprofen and thromboxane b2

ArticleYear
Prostaglandin I2 and thromboxane B2 biosynthesis and haemodynamic effects of lisinopril.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Compliance; Double-Blind Method; Enalapril; Epoprostenol; Female; Hemodynamics; Humans; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Thromboxane B2; Vascular Resistance

1991
Ibuprofen pretreatment inhibits prostacyclin release during abdominal exploration in aortic surgery.
    Anesthesiology, 1990, Volume: 72, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Abdomen; Adult; Aged; Aorta; Double-Blind Method; Epoprostenol; Female; Flushing; Hemodynamics; Humans; Ibuprofen; Male; Middle Aged; Premedication; Prospective Studies; Randomized Controlled Trials as Topic; Thromboxane B2

1990
Renal effects of ibuprofen, piroxicam, and sulindac in patients with asymptomatic renal failure. A prospective, randomized, crossover comparison.
    Annals of internal medicine, 1990, Apr-15, Volume: 112, Issue:8

    Topics: Adult; Aged; Creatinine; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Kidney; Kidney Failure, Chronic; Middle Aged; Piroxicam; Prospective Studies; Prostaglandins; Randomized Controlled Trials as Topic; Renal Circulation; Sulindac; Thromboxane B2

1990
Inhibition of cold-induced vasoconstriction with ketanserin.
    Microvascular research, 1985, Volume: 30, Issue:1

    Topics: Adult; Cold Temperature; Hand; Humans; Ibuprofen; Ketanserin; Ketoconazole; Male; Middle Aged; Piperidines; Regional Blood Flow; Serotonin; Skin Temperature; Thromboxane B2; Vasoconstriction

1985
Kinetics of ibuprofen effect on platelet and endothelial prostanoid release.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Platelets; Dose-Response Relationship, Drug; Double-Blind Method; Epoprostenol; Female; Humans; Ibuprofen; Kinetics; Male; Radioimmunoassay; Random Allocation; Thromboxane A2; Thromboxane B2; Time Factors

1985
Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment.
    Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; beta-Thromboglobulin; Blood Platelets; Fear; Female; Humans; Ibuprofen; Male; Methoxyhydroxyphenylglycol; Middle Aged; Monoamine Oxidase; Panic; Phobic Disorders; Platelet Factor 4; Psychological Tests; Thromboxane B2

1984
Beneficial effects of ibuprofen in pacing-induced myocardial ischemia.
    The American journal of cardiology, 1983, Mar-01, Volume: 51, Issue:5

    Topics: Angina Pectoris; Cardiac Pacing, Artificial; Cathepsin D; Cathepsins; Female; Humans; Ibuprofen; Lactates; Male; Middle Aged; Thromboxane B2

1983
Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Epoprostenol; Heart Function Tests; Heart Rate; Humans; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Prostaglandins; Thromboxane A2; Thromboxane B2; Vasodilator Agents

1996
Effects of ketoprofen and ibuprofen on platelet aggregation and prostanoid formation in man.
    European journal of clinical pharmacology, 1996, Volume: 51, Issue:3-4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Female; Humans; Ibuprofen; Ketoprofen; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Thromboxane B2

1996
Comparative effects of nabumetone, sulindac, and ibuprofen on renal function.
    The Journal of rheumatology, 1997, Volume: 24, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cross-Over Studies; Electrolytes; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Kidney; Middle Aged; Nabumetone; Prostaglandins; Sulindac; Thromboxane B2

1997
The impact of prostanoids on pulmonary gas exchange during abdominal surgery with mesenteric traction.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Abdominal; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Epoprostenol; Female; Humans; Ibuprofen; Injections, Intravenous; Intraoperative Care; Male; Mesentery; Middle Aged; Oxygen; Pancreatectomy; Placebos; Prospective Studies; Prostaglandins; Pulmonary Gas Exchange; Pulmonary Veins; Thromboxane B2; Traction

1997
Pharmacokinetic and pharmacodynamic interaction between the lipoxygenase inhibitor MK-0591 and the cyclooxygenase inhibitor ibuprofen in man.
    International journal of clinical pharmacology research, 1998, Volume: 18, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Digestive System; Double-Blind Method; Drug Interactions; Drug Tolerance; Humans; Ibuprofen; Indoles; Kidney; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Male; Quinolines; Thromboxane B2

1998
Vasopressor hormone response following mesenteric traction during major abdominal surgery.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:8

    Topics: Abdomen; Anesthesia, Epidural; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Catecholamines; Double-Blind Method; Epoprostenol; Female; Hemodynamics; Hormones; Humans; Hypotension; Ibuprofen; Male; Mesentery; Middle Aged; Prospective Studies; Renin; Thromboxane B2

1998
Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group.
    Critical care medicine, 1999, Volume: 27, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Epoprostenol; Female; Fever; Humans; Hypothermia; Ibuprofen; Interleukin-6; Male; Middle Aged; Multiple Organ Failure; Prospective Studies; Sepsis; Survival Analysis; Thromboxane B2; Time Factors; Tumor Necrosis Factor-alpha

1999
Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs.
    American journal of hypertension, 1999, Volume: 12, Issue:9 Pt 1

    Topics: Acetaminophen; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Butanones; Creatinine; Dinoprostone; Diuretics; Drug Interactions; Drug Therapy, Combination; Female; Fosinopril; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Middle Aged; Nabumetone; Renal Plasma Flow; Sodium; Sodium Chloride Symporter Inhibitors; Sulindac; Thromboxane B2

1999
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2

2000
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
    The New England journal of medicine, 2001, Dec-20, Volume: 345, Issue:25

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Drug Interactions; Drug Therapy, Combination; Humans; Ibuprofen; Isoenzymes; Lactones; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sulfones; Thromboxane B2

2001
In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:1

    Topics: Adult; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Microdialysis; Molar, Third; Oral Surgical Procedures; Pain Measurement; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substrate Specificity; Sulfonamides; Thromboxane B2; Tooth Extraction

2002
Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:1

    Topics: Adult; Algorithms; Alleles; Amino Acid Substitution; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Dinoprostone; Genotype; Half-Life; Humans; Ibuprofen; Male; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Thromboxane B2

2002
The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:5

    Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Bleeding Time; Blood Platelets; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Ibuprofen; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

2003
Double-blind, randomized, parallel, placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-treated healthy adult volunteers.
    Clinical therapeutics, 2005, Volume: 27, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Drug Antagonism; Female; Humans; Ibuprofen; Luminescent Measurements; Male; Middle Aged; Platelet Aggregation Inhibitors; Thromboxane B2

2005
Effects of cyclo-oxygenase inhibition on exhaled eicosanoids in patients with COPD.
    Thorax, 2005, Volume: 60, Issue:10

    Topics: Blood Gas Analysis; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Eicosanoids; Female; Forced Expiratory Volume; Humans; Ibuprofen; Lactones; Leukotriene B4; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Sputum; Sulfones; Thromboxane B2; Vital Capacity

2005
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3

    Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Celecoxib; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Myocardial Ischemia; Osteoarthritis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrazoles; Sulfonamides; Thromboxane B2; Treatment Outcome

2006
Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ibuprofen; Male; Nabumetone; Sulfonamides; Thromboxane B2

2009
The interaction of ibuprofen and diclofenac with aspirin in healthy volunteers.
    British journal of pharmacology, 2009, Volume: 157, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Drug Interactions; Female; Humans; Ibuprofen; Male; Middle Aged; Platelet Aggregation; Risk Factors; Thromboxane B2

2009

Other Studies

87 other study(ies) available for ibuprofen and thromboxane b2

ArticleYear
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16

    Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors

2003
Ibuprofen intervention in canine septic shock: reduction of pathophysiology without decreased cytokines.
    The Journal of surgical research, 1992, Volume: 53, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Cytokines; Dinoprostone; Dogs; Endotoxins; Escherichia coli Infections; Ibuprofen; Interleukin-6; Lipid Peroxidation; Shock, Septic; Superoxides; Thromboxane B2; Tumor Necrosis Factor-alpha

1992
Effects of cyclooxygenase inhibitors on ex vivo cysteinyl-leukotriene production by whole human blood allowed to clot spontaneously. Comparison to stimulated blood.
    Thrombosis research, 1992, Jul-01, Volume: 67, Issue:1

    Topics: Adult; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Aspirin; Blood Coagulation; Calcimycin; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Humans; Ibuprofen; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Thromboxane B2

1992
Ibuprofen pretreatment does not prevent hemodynamic instability after cemented arthroplasty in dogs.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arthroplasty; Dogs; Embolism, Fat; Hemodynamics; Ibuprofen; Infusions, Intravenous; Thromboxane B2

1992
Effect of cyclooxygenase inhibition on amphotericin B-induced lung injury in awake sheep.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Amphotericin B; Animals; Body Temperature; Ibuprofen; Infusions, Intravenous; Leukocyte Count; Lung; Lung Compliance; Pulmonary Ventilation; Pulmonary Wedge Pressure; Sheep; Thromboxane B2

1992
Effects of NSAIDs on beagle crevicular cyclooxygenase metabolites and periodontal bone loss.
    Journal of periodontal research, 1992, Volume: 27, Issue:3

    Topics: Administration, Oral; Administration, Topical; Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Flurbiprofen; Gingival Crevicular Fluid; Ibuprofen; Naproxen; Prostaglandins F; Thromboxane B2

1992
Ibuprofen therapy in experimental porcine gram-negative septic shock.
    Resuscitation, 1991, Volume: 22, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Escherichia coli Infections; Ibuprofen; Leukocyte Count; Peritonitis; Platelet Count; Pulmonary Circulation; Shock, Septic; Swine; Thromboxane B2; Vascular Resistance

1991
Ibuprofen improves survival but does not ameliorate increased gut mucosal permeability in endotoxic pigs.
    Archives of surgery (Chicago, Ill. : 1960), 1992, Volume: 127, Issue:1

    Topics: Animals; Hemodynamics; Hydrogen-Ion Concentration; Ibuprofen; Ileum; Intestinal Mucosa; Lipopolysaccharides; Male; Oxygen; Permeability; Shock, Septic; Swine; Thromboxane B2

1992
Excretion of metabolites of prostacyclin and thromboxane by rats with nephrotoxic nephritis: effects of interleukin-1.
    British journal of pharmacology, 1991, Volume: 103, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Creatinine; Cyclooxygenase Inhibitors; Epoprostenol; Ibuprofen; In Vitro Techniques; Interleukin-1; Kidney Glomerulus; Male; Nephritis; Neutrophils; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes

1991
Bacterial sepsis-induced decrease in lung vascular reactivity to 9,11-dideoxy-11a9a-epoxymethano-prostaglandin F2 alpha (U46619) in the rat.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bacterial Infections; Cyclooxygenase Inhibitors; Ibuprofen; Lung; Male; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Radioimmunoassay; Rats; Rats, Inbred Strains; Thromboxane B2

1990
Prostanoids determine the range of cerebral blood flow autoregulation of newborn piglets.
    Stroke, 1990, Volume: 21, Issue:5

    Topics: Animals; Animals, Newborn; Blood Pressure; Cerebrovascular Circulation; Homeostasis; Ibuprofen; Microspheres; Osmolar Concentration; Prostaglandin Antagonists; Prostaglandins; Swine; Thromboxane B2; Vascular Resistance

1990
Melittin stimulates liver glycogenolysis and the release of prostaglandin D2 and thromboxane B2.
    The Biochemical journal, 1990, Jul-01, Volume: 269, Issue:1

    Topics: Animals; Bee Venoms; Female; Glycogen; Ibuprofen; Indomethacin; Intercellular Signaling Peptides and Proteins; Kinetics; Liver; Melitten; Peptides; Prostaglandin D2; Rats; Rats, Inbred Strains; Thromboxane B2; Vasoconstriction; Wasp Venoms

1990
Stimulation of release of prostaglandin D2 and thromboxane B2 from perfused rat liver by extracellular adenosine.
    The Biochemical journal, 1990, Aug-15, Volume: 270, Issue:1

    Topics: Acetophenones; Adenosine; Animals; Blood Pressure; Glucose; Ibuprofen; Indomethacin; Liver; Male; Portal System; Prostaglandin D2; Rats; Rats, Inbred Strains; Secretory Rate; Sulfonamides; Thromboxane B2

1990
Early lung dysfunction after major burns: role of edema and vasoactive mediators.
    The Journal of trauma, 1985, Volume: 25, Issue:10

    Topics: Animals; Burns; Dextrans; Ibuprofen; Isotonic Solutions; Lung; Lung Compliance; Lymphatic System; Pulmonary Edema; Resuscitation; Ringer's Solution; Sheep; Thromboxane B2

1985
Platelet-activating factor-stimulated hepatic glycogenolysis is not mediated through cyclooxygenase-derived metabolites of arachidonic acid.
    The Journal of biological chemistry, 1989, Jul-25, Volume: 264, Issue:21

    Topics: Animals; Arachidonic Acids; Glucose; Ibuprofen; Liver; Liver Circulation; Liver Glycogen; Male; Platelet Activating Factor; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Reference Values; Thromboxane B2; Vascular Resistance

1989
Regulation of murine hematopoiesis by arachidonic acid metabolites.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:5

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acids; B-Lymphocytes; Cyclooxygenase Inhibitors; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Prostaglandins; Thromboxane B2; Umbelliferones

1989
Systemic and mesenteric O2 metabolism in endotoxic pigs: effect of ibuprofen and meclofenamate.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 67, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Endotoxins; Hemodynamics; Hydrogen-Ion Concentration; Ibuprofen; Lipopolysaccharides; Male; Meclofenamic Acid; Mesentery; ortho-Aminobenzoates; Oxygen; Shock, Septic; Swine; Thromboxane B2

1989
Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder.
    The American journal of physiology, 1985, Volume: 248, Issue:3 Pt 2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bufo marinus; Cells, Cultured; Cyclic AMP; Dinoprostone; Drug Interactions; Feedback; Female; Ibuprofen; Phospholipases; Phospholipids; Phosphorus Radioisotopes; Prostaglandins; Prostaglandins E; Stimulation, Chemical; Thromboxane B2; Urinary Bladder; Vasopressins

1985
Adenosine produces pulmonary vasoconstriction in sheep. Evidence for thromboxane A2/prostaglandin endoperoxide-receptor activation.
    Circulation research, 1989, Volume: 65, Issue:6

    Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Ibuprofen; Lung; Prostaglandin Endoperoxides; Pulmonary Circulation; Receptors, Purinergic; Sheep; Theophylline; Thromboxane A2; Thromboxane B2; Time Factors; Vasoconstriction

1989
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited.
    Annals of surgery, 1989, Volume: 209, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Epoprostenol; Ibuprofen; Ischemia; Kidney; Male; Organ Size; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2; Vasodilator Agents

1989
Prevention of chronic cerebral vasospasm in dogs with ibuprofen and high-dose methylprednisolone.
    Stroke, 1989, Volume: 20, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Dinoprostone; Dogs; Ibuprofen; Ischemic Attack, Transient; Methylprednisolone; Subarachnoid Hemorrhage; Thromboxane B2

1989
Mechanisms of late hemodynamic and airway dynamic responses to endotoxin in awake sheep.
    The American review of respiratory disease, 1989, Volume: 140, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Atropine; Blood Pressure; Endotoxins; Hemodynamics; Ibuprofen; Lung; Lung Compliance; Metaproterenol; Propranolol; Pulmonary Circulation; Pulmonary Gas Exchange; Respiratory Physiological Phenomena; Respiratory System; Sheep; Thromboxane B2

1989
Prostaglandins, leukotrienes, and other arachidonic acid metabolites in the pathogenesis of otitis media.
    The Laryngoscope, 1988, Volume: 98, Issue:9

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Chinchilla; Dinoprostone; Disease Models, Animal; Humans; Hydrocortisone; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukotriene B4; Middle Ear Ventilation; Otitis Media with Effusion; Penicillin G; Prostaglandins; Prostaglandins E; SRS-A; Temporal Bone; Thromboxane B2

1988
Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay.
    American journal of obstetrics and gynecology, 1986, Volume: 154, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Acid Phosphatase; Ascitic Fluid; Cell Count; Dinoprost; Endometriosis; Female; Humans; Ibuprofen; Infertility, Female; Laparoscopy; Macrophage Activation; Macrophages; Male; Menstrual Cycle; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Sperm-Ovum Interactions; Thromboxane B2

1986
Characteristics of thromboxane production by the isolated-perfused rat heart.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Heart; Ibuprofen; In Vitro Techniques; Methacrylates; Myocardium; Perfusion; Rats; Thromboxane B2

1987
Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect.
    The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cell Adhesion; Cyclooxygenase Inhibitors; Drug Interactions; Ibuprofen; Lymphatic System; Lymphocyte Activation; Meclofenamic Acid; Neutrophils; Pulmonary Circulation; Pulmonary Embolism; Sheep; Superoxides; Thrombin; Thromboxane B2; Vascular Resistance

1987
Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal-sparing effect of sulindac.
    Gastroenterology, 1986, Volume: 90, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Ibuprofen; Indenes; Kidney; Kidney Function Tests; Liver Cirrhosis, Alcoholic; Middle Aged; Prostaglandins E; Renal Circulation; Sulindac; Thromboxane B2; Time Factors

1986
Effects of ibuprofen on a pig Pseudomonas ARDS model.
    The Journal of surgical research, 1986, Volume: 40, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Disease Models, Animal; Ibuprofen; Oxygen; Pseudomonas Infections; Pulmonary Artery; Pulmonary Wedge Pressure; Radioimmunoassay; Respiratory Distress Syndrome; Swine; Thromboxane B2

1986
Direct and indirect effects of leukotriene D4 on the lungs of unanesthetized sheep.
    Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Female; Hypertension, Pulmonary; Ibuprofen; Imidazoles; Lung; Lung Compliance; Lymph; Male; Meclofenamic Acid; Prostaglandin-Endoperoxide Synthases; Pulmonary Wedge Pressure; Sheep; SRS-A; Thromboxane B2; Thromboxane-A Synthase

1987
Nonsteroidal anti-inflammatory drugs correct the bactericidal defect of polymorphonuclear leukocytes in a guinea pig model of thermal injury.
    The Journal of infectious diseases, 1988, Volume: 157, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Bactericidal Activity; Blood Cell Count; Burns; Complement System Proteins; Concanavalin A; Cyclooxygenase Inhibitors; Disease Models, Animal; Guinea Pigs; Ibuprofen; Indomethacin; Kinetics; Lymphocyte Activation; Neutrophils; Phagocytosis; Piroxicam; Pseudomonas aeruginosa; Spleen; Thromboxane B2

1988
A monoclonal anti-thromboxane B2 antibody.
    FEBS letters, 1988, May-09, Volume: 232, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Arachidonic Acid; Arachidonic Acids; Humans; Ibuprofen; Imidazoles; Immunoglobulin G; Indomethacin; Mice; Mice, Inbred BALB C; Platelet Aggregation; Radioimmunoassay; Thromboxane A2; Thromboxane B2

1988
Acute cigarette smoke exposure causes lung injury in rabbits treated with ibuprofen.
    Experimental lung research, 1987, Volume: 13, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Ibuprofen; Lung; Lung Diseases; Male; Nicotiana; Organometallic Compounds; Pentetic Acid; Plants, Toxic; Pulmonary Alveoli; Pulmonary Edema; Rabbits; Smoke; Technetium; Technetium Tc 99m Pentetate; Thromboxane B2; Time Factors

1987
[Protective effect of PGI2 on experimental ARDS and factors influencing it].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1987, Volume: 25, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Ibuprofen; Male; Oleic Acids; Rabbits; Respiratory Distress Syndrome; Thromboxane B2

1987
Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig.
    The American journal of physiology, 1988, Volume: 255, Issue:1 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Hemodynamics; Ibuprofen; Microspheres; Naloxone; Regional Blood Flow; Shock, Septic; Swine; Thromboxane B2

1988
Increased renal thromboxane production in murine lupus nephritis.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:1

    Topics: Animals; Dinoprostone; Female; Glomerulonephritis; Ibuprofen; Kidney; Kidney Glomerulus; Lupus Erythematosus, Systemic; Male; Mice; Mice, Inbred NZB; Prostaglandins E; Prostaglandins F; Proteinuria; Species Specificity; Thromboxane B2

1986
Topical ibuprofen decreases thromboxane release from the endotoxin-stimulated burn wound.
    The Journal of trauma, 1986, Volume: 26, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Blood Pressure; Burns; Endotoxins; Escherichia coli; Ibuprofen; Infusions, Parenteral; Lymph; Ointments; Oxygen; Skin Absorption; Thromboxane B2; Thromboxanes

1986
Myocardial ischemia: platelet and thromboxane concentrations in cardiac lymph and the effects of ibuprofen and prostacyclin.
    Circulation research, 1986, Volume: 59, Issue:1

    Topics: Animals; Blood Platelets; Coronary Disease; Dogs; Epoprostenol; Ibuprofen; Lymph; Platelet Aggregation; Platelet Count; Thromboxane B2

1986
Ibuprofen prevents synthetic smoke-induced pulmonary edema.
    The American review of respiratory disease, 1986, Volume: 134, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Drug Evaluation, Preclinical; Epoprostenol; Germ-Free Life; Hemodynamics; Hydrochloric Acid; Ibuprofen; Indomethacin; Lung; Male; Pulmonary Edema; Rats; Rats, Inbred Strains; Smoke; Thromboxane B2

1986
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.
    The Journal of surgical research, 1987, Volume: 42, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Blood Pressure; Dogs; Epoprostenol; Hemorrhage; Ibuprofen; Pancreatitis; Thromboxane B2

1987
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model.
    Circulatory shock, 1987, Volume: 21, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Capillary Permeability; Disease Models, Animal; Hemodynamics; Ibuprofen; Methylprednisolone; Pseudomonas Infections; Respiratory Distress Syndrome; Swine; Thromboxane B2

1987
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.
    Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Creatinine; Evaluation Studies as Topic; Ibuprofen; Imidazoles; Ischemia; Kidney; Kidney Tubular Necrosis, Acute; Male; Methacrylates; Pyridines; Rats; Thromboxane B2; Thromboxane-A Synthase

1987
Topical ibuprofen decreases early postburn edema.
    Surgery, 1987, Volume: 102, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Burns; Edema; Ibuprofen; Lymph; Prostaglandin Antagonists; Prostaglandins; Sheep; Thromboxane B2

1987
Low-dose dopamine preserves renal blood flow in endotoxin shocked dogs treated with ibuprofen.
    The Journal of surgical research, 1985, Volume: 38, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diuresis; Dogs; Dopamine; Female; Hemodynamics; Ibuprofen; Infusions, Parenteral; Male; Radioimmunoassay; Renal Circulation; Shock, Septic; Thromboxane B2

1985
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.
    Circulatory shock, 1985, Volume: 17, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Drug Therapy, Combination; Female; Gentamicins; Ibuprofen; Indomethacin; Methylprednisolone; Peritonitis; Rats; Shock, Septic; Thromboxane B2

1985
Role of subcutaneous tissue endotoxin in the production of prostanoid-induced lung injury: comparison with intravenous endotoxin response.
    Circulatory shock, 1985, Volume: 17, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Ibuprofen; Injections, Intravenous; Injections, Subcutaneous; Lung; Lung Injury; Lymph; Prostaglandins; Sheep; Thromboxane B2

1985
Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa.
    European journal of respiratory diseases, 1985, Volume: 67, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Disease Models, Animal; Ibuprofen; Inflammation; Kinetics; Lung; Male; Mice; Neutrophils; Pneumonia; Prostaglandins E; Pseudomonas Infections; Therapeutic Irrigation; Thromboxane B2

1985
Ibuprofen prevents Pasteurella hemolytica endotoxin-induced changes in plasma prostanoids and serotonin, and fever in sheep.
    Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Endotoxins; Female; Fever; Ibuprofen; Pasteurella; Pasteurella Infections; Prostaglandins; Prostaglandins F; Serotonin; Sheep; Sheep Diseases; Thromboxane B2; Thromboxanes

1985
Pulmonary dysfunction secondary to soft-tissue endotoxin.
    Archives of surgery (Chicago, Ill. : 1960), 1985, Volume: 120, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Escherichia coli; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Lung; Lung Diseases; Lymph; Lymphatic System; Muscles; Sheep; Thromboxane B2

1985
Prostacyclin and thromboxane A2 moderate postischemic renal failure.
    Surgery, 1985, Volume: 98, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Epoprostenol; Ibuprofen; Ischemia; Male; Methacrylates; Premedication; Rats; Renal Circulation; Thromboxane A2; Thromboxane B2; Thromboxanes

1985
Effect of prostaglandin blockers on ascites fluid in pancreatitis.
    Surgery, 1985, Volume: 98, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Ascitic Fluid; Biological Assay; Electrolytes; Epoprostenol; Female; Hemorrhage; Hydrogen-Ion Concentration; Ibuprofen; Methylprednisolone; Mice; Osmolar Concentration; Pancreatitis; Swine; Thromboxane B2

1985
Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Platelets; Chronic Disease; Dinoprost; Dinoprostone; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Glomerulonephritis; Humans; Ibuprofen; Kidney; Kidney Function Tests; Lupus Erythematosus, Systemic; Middle Aged; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thromboxane A2; Thromboxane B2

1985
Pulmonary transvascular fluid and protein exchange after thrombin-induced microembolism. Differential effects of cyclooxygenase inhibitors.
    The American review of respiratory disease, 1985, Volume: 132, Issue:1

    Topics: Animals; Blood Proteins; Capillary Permeability; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epoprostenol; Extracellular Space; Hemodynamics; Ibuprofen; Indomethacin; Lung; Lymph; Meclofenamic Acid; Pulmonary Embolism; Sheep; Thrombin; Thromboxane B2; Vascular Resistance

1985
Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia.
    Circulatory shock, 1985, Volume: 16, Issue:2

    Topics: Animals; Bronchitis; Gram-Negative Bacteria; Ibuprofen; Leukocyte Count; Methylprednisolone; Neutrophils; Rats; Rats, Inbred Strains; Respiratory Distress Syndrome; Shock, Septic; Thromboxane B2; Time Factors

1985
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:1

    Topics: Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinogen Degradation Products; Gentamicins; Ibuprofen; Imidazoles; Indomethacin; Macrophages; Male; Peritonitis; Prostaglandins; Prostaglandins F; Rats; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes

1983
Regional blood flow and pulmonary thromboxane release after sublethal endotoxin infusion in sheep.
    Surgery, 1984, Volume: 95, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Escherichia coli; Hemodynamics; Ibuprofen; Lung; Prostaglandins F; Regional Blood Flow; Sheep; Thromboxane A2; Thromboxane B2; Thromboxanes

1984
Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Cyclooxygenase Inhibitors; Endotoxins; Escherichia coli; Hemodynamics; Ibuprofen; Lung; Lung Compliance; Lymph; Meclofenamic Acid; Pulmonary Gas Exchange; Thromboxane B2

1983
Protective actions of ibuprofen in arachidonate-induced sudden death.
    Pharmacology, 1983, Volume: 27, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Pressure; Death, Sudden; Dose-Response Relationship, Drug; Ibuprofen; Male; Platelet Aggregation; Platelet Count; Rabbits; Thromboxane A2; Thromboxane B2

1983
Promotion of vascular patency in dermal burns with ibuprofen.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Vessels; Body Fluids; Burns; Fibrinolysis; Freezing; Ibuprofen; Imidazoles; Indomethacin; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Skin; Thromboxane B2; Time Factors; Wound Healing

1984
Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:4

    Topics: Animals; Blood Physiological Phenomena; Glomerular Filtration Rate; Glomerulonephritis; Ibuprofen; Kidney Glomerulus; Male; Methacrylates; Nephrotic Syndrome; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Renal Circulation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Effects of ibuprofen on a porcine model of acute respiratory failure.
    The Journal of surgical research, 1984, Volume: 36, Issue:4

    Topics: Acute Disease; Animals; Disease Models, Animal; Hemodynamics; Ibuprofen; Lung; Male; Pseudomonas Infections; Respiratory Insufficiency; Swine; Thromboxane B2

1984
Modification of inflammatory response to aspiration with ibuprofen.
    The American journal of physiology, 1982, Volume: 243, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Blood Pressure; Dogs; Epoprostenol; Ibuprofen; Inhalation; Kinetics; Leukocyte Count; Lung; Pulmonary Edema; Respiration; Thrombocytosis; Thromboxane B2

1982
Leukotriene D4: a potent coronary artery vasoconstrictor associated with impaired ventricular contraction.
    Science (New York, N.Y.), 1982, Aug-27, Volume: 217, Issue:4562

    Topics: Animals; Blood Pressure; Chromones; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Female; Heart Ventricles; Ibuprofen; Male; Myocardial Contraction; Sheep; SRS-A; Thromboxane B2; Vasoconstriction

1982
Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus.
    Clinical immunology and immunopathology, 1982, Volume: 25, Issue:2

    Topics: Alprostadil; Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Cyclooxygenase Inhibitors; DNA; Female; Ibuprofen; Kidney Glomerulus; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Prostaglandin Antagonists; Prostaglandins E; Proteinuria; Thromboxane B2

1982
Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Blood Platelets; Blood Vessels; Endothelium; Epoprostenol; Humans; Ibuprofen; In Vitro Techniques; Platelet Adhesiveness; Prostaglandins; Thromboxane A2; Thromboxane B2

1981
Adverse effects of prostacyclin used to perfuse isolated lung lobes.
    The American journal of physiology, 1982, Volume: 242, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Biomechanical Phenomena; Dogs; Epoprostenol; Ibuprofen; Lung; Perfusion; Platelet Count; Prostaglandins; Thromboxane B2

1982
Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation. A possible mechanism for its efficacy in bacteremic shock.
    JAMA, 1982, Mar-12, Volume: 247, Issue:10

    Topics: Animals; Cell Aggregation; Cricetinae; Depression, Chemical; Granulocytes; Humans; Ibuprofen; Platelet Aggregation; Scopolamine Derivatives; Shock, Septic; Solanaceous Alkaloids; Structure-Activity Relationship; Thromboxane B2; Thromboxanes; Vasodilator Agents

1982
Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia.
    Advances in shock research, 1980, Volume: 3

    Topics: Animals; Blood Pressure; Cats; Central Venous Pressure; Coronary Vessels; Female; Heart Rate; Ibuprofen; Male; Myocardial Infarction; Thromboxane B2; Vasodilation

1980
Ibuprofen improves survival from endotoxic shock in the rat.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1

    Topics: Acid Phosphatase; Animals; Fibrin Fibrinogen Degradation Products; Glucuronidase; Ibuprofen; Lysosomes; Male; Prostaglandins F; Rats; Shock, Septic; Thromboxane B2

1980
Equipotent inhibition by R(-)-, S(+)- and racemic ibuprofen of human polymorphonuclear cell function in vitro.
    British journal of clinical pharmacology, 1993, Volume: 35, Issue:3

    Topics: Blood Platelets; Cyclooxygenase Inhibitors; Glucuronidase; Humans; Ibuprofen; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Aggregation; Stereoisomerism; Superoxides; Thromboxane B2

1993
Platelet-activating factor-induced human eosinophil activation. Generation and release of cyclo-oxygenase metabolites in human blood eosinophils from asthmatics.
    Immunology, 1993, Volume: 78, Issue:2

    Topics: Asthma; Cells, Cultured; Dose-Response Relationship, Drug; Eosinophils; Humans; Ibuprofen; Leukocytes; Platelet Activating Factor; Prostaglandins; Thromboxane B2

1993
Cecal ligation and puncture is associated with pulmonary injury in the rat: role of cyclooxygenase pathway products.
    Prostaglandins, 1993, Volume: 45, Issue:4

    Topics: Animals; Bronchoalveolar Lavage Fluid; Capillaries; Capillary Permeability; Cecum; Ibuprofen; Ligation; Lung; Lung Diseases; Male; Prostaglandin-Endoperoxide Synthases; Punctures; Rats; Rats, Sprague-Dawley; Sepsis; Thromboxane B2

1993
Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition.
    Annals of surgery, 1993, Volume: 217, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Acidosis; Animals; Antibodies, Monoclonal; Bicarbonates; Blood Pressure; Carbon Dioxide; Cause of Death; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Epoprostenol; Ibuprofen; Male; Oxygen; Rats; Rats, Sprague-Dawley; Thromboxane B2; Tumor Necrosis Factor-alpha

1993
Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases.
    British journal of pharmacology, 1997, Volume: 122, Issue:3

    Topics: Blood Platelets; Blotting, Western; Coenzyme A; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Esters; Humans; Ibuprofen; In Vitro Techniques; Isoenzymes; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Sulfides; Thromboxane B2

1997
Cytoprotection by the osmolytes betaine and taurine in ischemia-reoxygenation injury in the perfused rat liver.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Betaine; Cytoprotection; Dinoprostone; Hyaluronic Acid; Ibuprofen; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Osmolar Concentration; Perfusion; Prostaglandin D2; Rats; Rats, Wistar; Reperfusion Injury; Taurine; Thromboxane B2

1997
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-05, Volume: 96, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; Humans; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Middle Aged; Monocytes; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2

1999
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.
    British journal of pharmacology, 1999, Volume: 126, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Carrageenan; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; In Vitro Techniques; Inflammation; Knee Joint; Male; N-Methylaspartate; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Thromboxane B2

1999
Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 60, Issue:3

    Topics: Animals; Blood Pressure; Cardiovascular System; Cyclooxygenase Inhibitors; Endotoxemia; Ibuprofen; Leukotrienes; Lung; Nitric Oxide; Rats; Thromboxane B2; Vasoconstriction

1999
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2

1999
In vivo lipid peroxidation and platelet activation in cystic fibrosis.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:4 Pt 1

    Topics: Adolescent; Adult; Child; Cyclooxygenase Inhibitors; Cystic Fibrosis; Dinoprost; F2-Isoprostanes; Female; Genotype; Humans; Ibuprofen; Lipid Peroxidation; Lung; Male; Platelet Activation; Sulfonamides; Thromboxane B2; Vitamin E

2000
Association between ibuprofen, aspirin therapy found.
    Journal of the American Dental Association (1939), 2002, Volume: 133, Issue:3

    Topics: Aspirin; Drug Interactions; Humans; Ibuprofen; Platelet Aggregation; Thromboxane B2

2002
Effects of ibuprofen on the physiology and outcome of rabbit endotoxic shock.
    BMC infectious diseases, 2002, Oct-31, Volume: 2

    Topics: Animals; Blood Pressure; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Heart Rate; Hematocrit; Ibuprofen; Leukocyte Count; Platelet Count; Rabbits; Random Allocation; Respiration; Shock, Septic; Thromboxane B2

2002
Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells.
    Vascular pharmacology, 2007, Volume: 46, Issue:2

    Topics: Animals; Aorta, Abdominal; Basilar Artery; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Ibuprofen; Imines; In Vitro Techniques; Methacrylates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Swine; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Vasoconstriction; Vasodilation

2007
S-ibuprofen effectively inhibits thromboxane B2 levels and platelet function in an experimental model of lipopolysaccharide-stimulated and non-stimulated whole blood.
    Pharmacology, 2008, Volume: 81, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Lipopolysaccharides; Male; Platelet Aggregation; Platelet Function Tests; Stereoisomerism; Thromboxane B2; Whole Blood Coagulation Time

2008
Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys.
    Prostaglandins & other lipid mediators, 2008, Volume: 85, Issue:3-4

    Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Animals, Newborn; Animals, Suckling; Cyclooxygenase 2; Dinoprost; Dinoprostone; Ductus Arteriosus, Patent; Ibuprofen; Indomethacin; Kidney; Prostaglandins; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thromboxane B2

2008
Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Dinoprostone; Dose-Response Relationship, Drug; Female; Flurbiprofen; Humans; Ibuprofen; Leukocytes; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2

2010
Influence of nonsteroidal anti-inflammatory drugs on the antiplatelet effects of aspirin in rats.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:2

    Topics: Acetylation; Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Drug Interactions; Etodolac; Ibuprofen; Male; Phenylpropionates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thromboxane B2

2011
Human retinal endothelial cells and astrocytes cultured on 3-D scaffolds for ocular drug discovery and development.
    Prostaglandins & other lipid mediators, 2018, Volume: 134

    Topics: Astrocytes; Biomimetics; Coculture Techniques; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Drug Discovery; Drug Interactions; Endothelial Cells; Humans; Ibuprofen; Ketorolac; Retina; Thromboxane B2

2018