ibuprofen and thromboxane a2

ibuprofen has been researched along with thromboxane a2 in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (64.10)	18.7374
1990's	8 (20.51)	18.2507
2000's	4 (10.26)	29.6817
2010's	2 (5.13)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jin, N; Packer, CS; Patterson, CE; Rhoades, RA	1
Baum, TD; Feldman, HS; Fink, MP; Heard, SO; Latka, C	1
Bernard, GR; Halushka, PV; Higgins, SB; Metz, CA; Reines, HD; Swindell, BB; Vrbanac, JJ; Watts, FL; Wright, PE	1
Dandona, P; Gill, J; Jeremy, JY	1
Biaggioni, I; Enayat, N; King, LS; Newman, JH; Robertson, D	1
Goldman, G; Hechtman, HB; Klausner, JM; Kobzik, L; Paterson, IS; Shepro, D; Valeri, CR	1
Cheng, CY; Leggett, CG; Reese, AC	1
Alexander, F; Hechtman, HB; Huval, W; Lelcuk, S; Mannick, JA; Palder, SB; Shepro, D	1
Hall, ED; Wolf, DL	1
Bonati, M; Gaspari, F; Livio, M; Orisio, S; Remuzzi, G; Viganò, G	1
Brune, K; Reinke, M	1
Klausner, JM; Lelcuk, S; Merhav, A; Rozin, RR	1
Mäkäräinen, L; Ylikorkala, O	1
Brigham, KL; Butka, BJ; Newman, JH	1
Beyers, BJ; Bowen, RJ; Longenecker, GL; Shah, AK; Swift, IA	1
Alexander, F; Hechtman, HB; Kobzik, L; Lelcuk, S; Shepro, D; Valeri, CR	1
Bombardieri, S; Ciabattoni, G; Cinotti, GA; Di Munno, O; Gotti, E; Patrono, C; Pierucci, A; Remuzzi, G; Simonetti, BM; Tartarelli, G	1
Demling, RH; Hechtman, H; Lalonde, CC; Wenger, H; West, K; Wong, C	1
Butler, RR; Cook, JA; Halushka, PV; Wise, WC	1
Allen, PD; Hechtman, HB; Huval, WV; Lelcuk, S; Mannick, JA; Shepro, D	1
Ehrlich, HP	1
Hill, RD; Hüttemeier, PC; Kong, D; Schuette, AH; Watkins, WD; Wonders, TR; Zapol, WM	1
Casey, LC; Fink, MP; MacVittie, TJ	1
Burke, SE; Lefer, AM; Roth, DM	1
Almqvist, PM; Kuenzig, M; Schwartz, SI	1
Carson, SN; Hunter, GC	1
Cook, JA; Halushka, PV; Wise, WC	1
Czervionke, RL; Hoak, JC; Parks, WM	1
Carrow, BA; Lefer, AM; Smith, EF	1
Arosio, E; Campedelli, A; Degan, M; Lechi, A; Minuz, P; Pancera, P; Priante, F; Ribul, M	1
Fletcher, JR; Khimenko, PL; Logsdon, P; Rizzo, A; Taylor, AE; Townsley, MI	1
Arosio, E; Lechi, A; Minuz, P; Pancera, P; Pirante, F; Ribul, M	1
Abran, D; Chemtob, S; Varma, DR	1
Barnard, MR; Frelinger, AL; Laposata, M; Linden, MD; Michelson, AD; Morris, JE; O'Sullivan, BP; Salem, RO; Spencer-Manzon, M	1
Hashiguchi, Y; Ishiguro, S; Miyamoto, A; Nishio, A; Obi, T	1
Dager, W; Ellison, J	1
Bailey, SR; Berhane, Y; Brooks, AC; Elliott, J; Menzies-Gow, NJ	1
Alcay, S; Altinbas, B; Erkan, LG; Guvenc, G; Toker, MB; Udum Kucuksen, D; Ustuner, B; Yalcin, M	1
Altinbas, B; Erkan, LG; Guvenc, G; Niaz, N; Yalcin, M	1

Trials

6 trial(s) available for ibuprofen and thromboxane a2

Article	Year
Prostacyclin and thromboxane A2 formation is increased in human sepsis syndrome. Effects of cyclooxygenase inhibition. The American review of respiratory disease, 1991, Volume: 144, Issue:5 Topics: Cyclooxygenase Inhibitors; Double-Blind Method; Epoprostenol; Humans; Ibuprofen; Multiple Organ Failure; Sepsis; Syndrome; Thromboxane A2; Time Factors	1991
Primary and myoma-associated menorrhagia: role of prostaglandins and effects of ibuprofen. British journal of obstetrics and gynaecology, 1986, Volume: 93, Issue:9 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Endometrium; Epoprostenol; Female; Humans; Ibuprofen; Leiomyoma; Menorrhagia; Middle Aged; Random Allocation; Thromboxane A2; Uterine Neoplasms	1986
Kinetics of ibuprofen effect on platelet and endothelial prostanoid release. Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Platelets; Dose-Response Relationship, Drug; Double-Blind Method; Epoprostenol; Female; Humans; Ibuprofen; Kinetics; Male; Radioimmunoassay; Random Allocation; Thromboxane A2; Thromboxane B2; Time Factors	1985
Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA). Annals of surgery, 1984, Volume: 199, Issue:2 Topics: Aged; Aorta, Abdominal; Aortic Aneurysm; Blood Platelets; Epoprostenol; Female; Heart; Hematologic Tests; Hemodynamics; Humans; Ibuprofen; Ligation; Male; Middle Aged; Myocardial Contraction; Myocardial Infarction; Papillary Muscles; Pulmonary Wedge Pressure; Serotonin; Thromboxane A2; Thromboxanes	1984
Amlodipine and haemodynamic effects of cyclo-oxygenase inhibition. British journal of clinical pharmacology, 1995, Volume: 39, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Amlodipine; Biomarkers; Blood Pressure; Creatinine; Cross-Over Studies; Cyclooxygenase Inhibitors; Epoprostenol; Heart Rate; Hemodynamics; Humans; Hypertension; Ibuprofen; Male; Middle Aged; Outpatients; Renin; Single-Blind Method; Thromboxane A2; Ultrasonography; Vascular Resistance; Vasodilator Agents	1995
Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients. Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Epoprostenol; Heart Function Tests; Heart Rate; Humans; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Prostaglandins; Thromboxane A2; Thromboxane B2; Vasodilator Agents	1996

Other Studies

33 other study(ies) available for ibuprofen and thromboxane a2

Article	Year
Activated neutrophils alter contractile properties of the pulmonary artery. American journal of respiratory cell and molecular biology, 1992, Volume: 6, Issue:3 Topics: Animals; Catalase; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Methacrylates; Muscle Contraction; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Artery; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane-A Synthase	1992
Lipopolysaccharide-induced myocardial depression is not mediated by cyclooxygenase products. Critical care medicine, 1991, Volume: 19, Issue:5 Topics: Animals; Depression, Chemical; Escherichia coli; Ibuprofen; In Vitro Techniques; Lipopolysaccharides; Male; Myocardial Contraction; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thromboxane A2	1991
Indomethacin and ibuprofen inhibit the uptake of 45Ca2+ by washed human platelets through a thromboxane A2-independent mechanism. European journal of pharmacology, 1990, Oct-02, Volume: 187, Issue:1 Topics: Blood Platelets; Calcimycin; Calcium; Calcium Radioisotopes; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Thromboxane A2	1990
Adenosine produces pulmonary vasoconstriction in sheep. Evidence for thromboxane A2/prostaglandin endoperoxide-receptor activation. Circulation research, 1989, Volume: 65, Issue:6 Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Ibuprofen; Lung; Prostaglandin Endoperoxides; Pulmonary Circulation; Receptors, Purinergic; Sheep; Theophylline; Thromboxane A2; Thromboxane B2; Time Factors; Vasoconstriction	1989
Thromboxane A2 mediates increased pulmonary microvascular permeability following limb ischemia. Circulation research, 1989, Volume: 64, Issue:6 Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Drug Combinations; Fatty Acids, Unsaturated; Female; Hydrazines; Ibuprofen; Ischemia; Leg; Lung; Methacrylates; Microcirculation; Pulmonary Artery; Reperfusion; Sheep; Thromboxane A2; Thromboxane-A Synthase	1989
Role of prostaglandins in controlling plasma fibronectin levels. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 188, Issue:4 Topics: Animals; Epoprostenol; Fibronectins; Ibuprofen; Imidazoles; Indomethacin; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane A2	1988
Reduction of polymorphonuclear leukocyte accumulations by inhibition of cyclooxygenase and thromboxane syntase in the rabbit. Surgery, 1986, Volume: 99, Issue:1 Topics: Animals; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Ibuprofen; Imidazoles; Male; Methacrylates; Neutrophils; Premedication; Prostaglandin-Endoperoxide Synthases; Rabbits; Skin; Skin Tests; Thromboxane A2; Thromboxane-A Synthase	1986
A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia. Journal of neurosurgery, 1986, Volume: 64, Issue:6 Topics: Animals; Benzofurans; Calcium Channel Blockers; Cats; Cyclooxygenase Inhibitors; Diltiazem; Dinoprost; Epoprostenol; Female; Ibuprofen; Ischemia; Male; Meclofenamic Acid; Nifedipine; Prostaglandin Antagonists; Prostaglandins F; Spinal Cord; Thromboxane A2; Verapamil; Vitamin E	1986
Aspirin prolongs bleeding time in uremia by a mechanism distinct from platelet cyclooxygenase inhibition. The Journal of clinical investigation, 1987, Volume: 79, Issue:6 Topics: Acetylation; Adult; Aged; Aspirin; Bleeding Time; Blood Platelets; Cyclooxygenase Inhibitors; Female; Hemorrhagic Disorders; Humans; Ibuprofen; Kinetics; Male; Middle Aged; Platelet Function Tests; Thromboxane A2; Uremia	1987
A monoclonal anti-thromboxane B2 antibody. FEBS letters, 1988, May-09, Volume: 232, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Arachidonic Acid; Arachidonic Acids; Humans; Ibuprofen; Imidazoles; Immunoglobulin G; Indomethacin; Mice; Mice, Inbred BALB C; Platelet Aggregation; Radioimmunoassay; Thromboxane A2; Thromboxane B2	1988
Prostacyclin (PGI2) and thromboxane (Tx) A2: mediators of wound healing. Israel journal of medical sciences, 1987, Volume: 23, Issue:7 Topics: Animals; Epoprostenol; Ibuprofen; Methacrylates; Rabbits; Thromboxane A2; Wound Healing	1987
Thromboxane A2 and prostacyclin do not modulate pulmonary hemodynamics during exercise in sheep. Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Epoprostenol; Hemodynamics; Hypoxia; Ibuprofen; Imidazoles; Lung; Lymph; Meclofenamic Acid; Physical Exertion; Pulmonary Artery; Sheep; Thromboxane A2; Vascular Resistance	1986
Prostacyclin and thromboxane A2 moderate postischemic renal failure. Surgery, 1985, Volume: 98, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Epoprostenol; Ibuprofen; Ischemia; Male; Methacrylates; Premedication; Rats; Renal Circulation; Thromboxane A2; Thromboxane B2; Thromboxanes	1985
Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus. The Journal of clinical investigation, 1985, Volume: 76, Issue:3 Topics: Adolescent; Adult; Aged; Blood Platelets; Chronic Disease; Dinoprost; Dinoprostone; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Glomerulonephritis; Humans; Ibuprofen; Kidney; Kidney Function Tests; Lupus Erythematosus, Systemic; Middle Aged; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thromboxane A2; Thromboxane B2	1985
Endotoxin-induced prostanoid production by the burn wound can cause distant lung dysfunction. Surgery, 1986, Volume: 99, Issue:4 Topics: Animals; Burns; Endotoxins; Hemodynamics; Ibuprofen; Injections, Intravenous; Lung Diseases; Lymph; Pulmonary Artery; Sheep; Thromboxane A2; Thromboxanes; Time Factors	1986
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:1 Topics: Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinogen Degradation Products; Gentamicins; Ibuprofen; Imidazoles; Indomethacin; Macrophages; Male; Peritonitis; Prostaglandins; Prostaglandins F; Rats; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes	1983
Anti-inflammatory drugs in the vascular response to burn injury. The Journal of trauma, 1984, Volume: 24, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Blood Coagulation; Burns; Epoprostenol; Hydrocortisone; Ibuprofen; Imidazoles; Ischemia; Male; Rats; Rats, Inbred Strains; Skin; Thromboxane A2; Time Factors; Vasodilation	1984
Regional blood flow and pulmonary thromboxane release after sublethal endotoxin infusion in sheep. Surgery, 1984, Volume: 95, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Escherichia coli; Hemodynamics; Ibuprofen; Lung; Prostaglandins F; Regional Blood Flow; Sheep; Thromboxane A2; Thromboxane B2; Thromboxanes	1984
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis. Annals of surgery, 1984, Volume: 200, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Dogs; Escherichia coli Infections; Female; Hemodynamics; Ibuprofen; Indomethacin; Male; Oxygen Consumption; Peritonitis; Prostaglandin Antagonists; Prostaglandins; Sepsis; Shock, Septic; Thromboxane A2	1984
Protective actions of ibuprofen in arachidonate-induced sudden death. Pharmacology, 1983, Volume: 27, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Pressure; Death, Sudden; Dose-Response Relationship, Drug; Ibuprofen; Male; Platelet Aggregation; Platelet Count; Rabbits; Thromboxane A2; Thromboxane B2	1983
Treatment of experimental canine endotoxin shock with ibuprofen, a cyclooxygenase inhibitor. Circulatory shock, 1984, Volume: 13, Issue:3 Topics: Animals; Blood Pressure; Dogs; Female; Hematocrit; Hypotension; Ibuprofen; Leukocyte Count; Lung; Male; Platelet Aggregation; Platelet Count; Shock, Septic; Thromboxane A2; Time Factors	1984
Arterial wall thromboxane: dominance after surgery predisposes to thrombosis. Journal of vascular surgery, 1984, Volume: 1, Issue:2 Topics: Animals; Blood Vessel Prosthesis; Carotid Arteries; Graft Occlusion, Vascular; Ibuprofen; Sheep; Thrombosis; Thromboxane A2; Thromboxanes	1984
Implications for thromboxane A2 in the pathogenesis of endotoxic shock. Advances in shock research, 1981, Volume: 6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Disseminated Intravascular Coagulation; Fibrin Fibrinogen Degradation Products; Ibuprofen; Indomethacin; Male; Muridae; Prostaglandins E; Prostaglandins F; Shock, Septic; Thromboxane A2; Thromboxanes	1981
Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Blood Platelets; Blood Vessels; Endothelium; Epoprostenol; Humans; Ibuprofen; In Vitro Techniques; Platelet Adhesiveness; Prostaglandins; Thromboxane A2; Thromboxane B2	1981
Effects of flurbiprofen on myocardial cell damage in acute myocardial ischemia. Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:3 Topics: Acute Disease; Animals; Blood Pressure; Cats; Cell Membrane; Coronary Disease; Creatine Kinase; Electrocardiography; Flurbiprofen; Heart; Heart Rate; Ibuprofen; Lysosomes; Male; Oxygenases; Platelet Aggregation; Propionates; Thromboxane A2; Vascular Resistance	1980
Platelet-activating factor increases vascular resistance in rat hindquarters by thromboxane A2. The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 2 Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Hindlimb; Ibuprofen; Male; Phenylacetates; Platelet Activating Factor; Rats; Rats, Wistar; Regional Blood Flow; Sulfonamides; Thromboxane A2; Thromboxanes; Triazoles; Vascular Resistance	1995
Regulation of prostanoid vasomotor effects and receptors in choroidal vessels of newborn pigs. The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Animals, Newborn; Choroid; Cyclic AMP; Cyclic GMP; Dinoprost; Down-Regulation; Epoprostenol; Ibuprofen; Inositol 1,4,5-Trisphosphate; Nitric Oxide; Nitroarginine; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins, Synthetic; Receptors, Prostaglandin; Swine; Thromboxane A2; Vasoconstrictor Agents; Vasodilation	1997
Platelet activation in cystic fibrosis. Blood, 2005, Jun-15, Volume: 105, Issue:12 Topics: Adenylyl Cyclases; Adolescent; Adult; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blood Platelets; Blotting, Western; Case-Control Studies; Cell Membrane; Child; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fatty Acids; Genotype; Humans; Ibuprofen; Inflammation; Leukocytes; Monocytes; Neutrophils; P-Selectin; Platelet Activation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboxane A2; Time Factors; Vitamin E	2005
Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells. Vascular pharmacology, 2007, Volume: 46, Issue:2 Topics: Animals; Aorta, Abdominal; Basilar Artery; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Ibuprofen; Imines; In Vitro Techniques; Methacrylates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Swine; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Vasoconstriction; Vasodilation	2007
Recent FDA warning of the concomitant use of aspirin and ibuprofen and the effects on platelet aggregation. Preventive cardiology, 2007,Spring, Volume: 10, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Interactions; Humans; Ibuprofen; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2; United States; United States Food and Drug Administration	2007
Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin. American journal of veterinary research, 2008, Volume: 69, Issue:3 Topics: Animals; Cyclic GMP; Cycloheximide; Cyclooxygenase 2; Endothelial Cells; Endothelin-1; Enzyme Inhibitors; Epoprostenol; Forelimb; Horse Diseases; Horses; Ibuprofen; Immunohistochemistry; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Thromboxane A2	2008
Brain thromboxane A2 via arachidonic acid cascade induces the hypothalamic-pituitary-gonadal axis activation in rats. Autonomic neuroscience : basic & clinical, 2015, Volume: 189 Topics: Animals; Arachidonic Acid; Benzofurans; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Follicle Stimulating Hormone; Growth Hormone-Releasing Hormone; Ibuprofen; Infusions, Intraventricular; Luteinizing Hormone; Male; Prostaglandin-Endoperoxide Synthases; Rats, Sprague-Dawley; Signal Transduction; Sperm Count; Sperm Motility; Testosterone; Thromboxane A2; Time Factors	2015
The effects of centrally injected arachidonic acid on respiratory system: Involvement of cyclooxygenase to thromboxane signaling pathway. Respiratory physiology & neurobiology, 2016, Volume: 225 Topics: Anesthesia; Animals; Arachidonic Acid; Benzofurans; Carbon Dioxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ibuprofen; Injections, Intraventricular; Male; Oxygen; Prostaglandin-Endoperoxide Synthases; Rats, Sprague-Dawley; Respiration; Respiratory System; Respiratory System Agents; Thromboxane A2; Tidal Volume; Time Factors	2016