ibuprofen and sulindac

ibuprofen has been researched along with sulindac in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (40.95)	18.7374
1990's	16 (15.24)	18.2507
2000's	20 (19.05)	29.6817
2010's	25 (23.81)	24.3611
2020's	1 (0.95)	2.80

Authors

Authors	Studies
Hannah, J; Holtz, WJ; Houser, RA; Jones, H; Kelly, KW; Matzuk, AR; Ruyle, WV; Sarett, LH; Shen, TY; Witzel, BE	1
Capiris, T; Cetenko, WJ; Connor, DT; Dyer, RD; Flynn, DL; Kostlan, CR; Nies, DE; Schrier, DJ; Sircar, JC	1
Duffy, EM; Jorgensen, WL	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Barreiro, EJ; Fraga, CA; Lima, LM; Romeiro, NC; Sant'Anna, CM	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Horie, T; Horiguchi, A; Kitamura, S; Kotake, Y; Ohshita, H; Ohta, S; Sanoh, S; Sugihara, K; Tateno, C; Tayama, Y	1
Kumar, M; Sinha, VR; Thareja, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Alcaraz, B; Bratoeff, E; Cabeza, M; Camacho-Arroyo, I; Garrido, M; González-Arenas, A	1
Chen, T; Guan, J; Liao, J; Luo, J; Qin, X; Talley, JJ; Tortorella, MD; Tu, Z; Zhang, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Onadeko, BO; Oyemade, GA	1
Miehlke, K	1
Burdeĭnyĭ, AP	1
Pemberton, RE; Strand, LJ	1
Burry, HC; Witherington, L	1
Baumgartner, H	1
Abe, K; Akiu, N; Saito, T; Sato, M; Takeuchi, K; Yasujima, M; Yoshinaga, K	1
Castonguay, A; Jalbert, G	1
Klassen, DK; Spilman, PS; Stout, RL; Whelton, A	1
Barrow, SE; Cockcroft, JR; Minuz, P; Ritter, JM	1
Epstein, C; Kinberg-Calhoun, J; Mullane, JF; Sanda, M; Shand, DG	1
Daskalopoulos, G; Gentilini, P; Hsueh, W; Kronborg, I; Laffi, G; Zipser, RD	1
Cohen, KL; Harris, S	1
Anderson, WP; Bobik, A	1
Penning, TM; Smithgall, TE	1
Campese, V; Horton, R; McKay, M; Nadler, JL; Vrbanac, J	1
Altman, R	1
Gribnau, FW; Koopmans, PP; Thien, T	1
Anderson, SA; Brater, DC; Brown-Cartwright, D	1
Blake, JW; Tobin, T; Weckman, T; Woods, WE	1
Anderson, S; Baird, B; Brater, DC; Campbell, WB	1
Chremos, AN; Ferguson, RK; Johnson, CL; Riley, LJ; Rotmensch, HH; Swanson, BN; Vlasses, PH	1
Condorelli, M; Cuocolo, A; De Simone, A; Patrignani, P; Ricciardelli, B; Saccà, L; Trimarco, B; Volpe, M	1
DiVincenzo, C; Pearlman, F; Phair, JP; Venezio, FR	1
Barsotti, P; Ciabattoni, G; Cinotti, GA; Manzi, M; Patrono, C; Pecci, G; Pierucci, A; Pugliese, F; Simonetti, BM; Taggi, F	1
Currie, WJ; Fyvie, A; Hayes, TB; Janke, PG; Vandenburg, MJ	1
Altman, RD	1
Ward, JR	1
Melvin, JR; Osyamkpe, CO; Sanfilippo, JS; Teichman, J; Wittliff, JL	1
Adachi, M; Fujimori, I; Hayakawa, M; Iizuka, K; Katsu, M; Kohno, M; Noguchi, T; Ogihara, K; Sekita, K; Takeda, Y	1
Chremos, AN; Dunn, MJ; Zambraski, EJ	1
Machtey, I; Ouaknine, L	1
Albert, KS; Gernaat, CM	1
Bhalla, AK; Simon, LS	1
Currie, WJ; VandenBurg, MJ; Walker, JW	1
Currie, WJ; Diggins, JB; Janke, PG; Vandenburg, MJ	1
Obel, AO	1
Admani, AK; Verma, S	1
Albert, KS; Dittert, LW; Juhl, RP; Smith, RB; Van Thiel, DH	1
Mills, JA; Simon, LS	1
Ghosh, AK; Rastogi, AK	2
Pathy, MS	1
Lindsley, CB	1
Nash, DP	1
Brandt, KD; Palmoski, MJ	1
Black, PK; Brater, DC; Haag, KM; Hall, SD; Kuzmik, DD; Manatunga, AK; Mullin, MA; Murray, MD	1
Bilodeau, JF; Castonguay, A; Chung, FL; Wang, M	1
Akatsu, T; Consolaro, A; Guimarães, SA; Tago, EM	1
Fowler, CJ; Stenström, A; Tiger, G	1
Jansen, JB; Peters, WH; Tiemessen, DM; van Lieshout, EM	1
Caldwell, J; Kenna, JG; Wade, LT	1
Cook, ME; Garcia, MM; Kadowitz, PJ; Lipani, JA; McNamara, DB; Poland, M; Thakur, VD; Wallin, JD	1
Becker, P; Brater, DC; Brizendine, E; Haag, K; Lazaridis, EN; Murray, MD	1
Peters, WH; Roelofs, HM; Tiemessen, DM; Van Lieshout, EM	1
Langenbach, R; Morham, SG; Young, DA; Zhang, X	1
Cook, ME; Thakur, V; Wallin, JD	1
Belder, D; Husmann, H; Warnke, J	1
Borgo, S; Castillo, E; Hasan, I; Rigas, B; Traganos, F; Williams, JL	1
Bulter, T; Das, P; Eriksen, JL; Findlay, KA; Golde, TE; Kang, DE; Koo, EH; Marquez-Sterling, N; Murphy, MP; Pietrzik, CU; Sagi, SA; Smith, TE; Wang, R; Weggen, S	1
Bhagat, K	1
Gao, X; Li, M; Song, S; Sun, F; Sun, H; Sun, S; Zhang, W	1
Brooks, G; Crabbe, MJ; Harper, JV; Shattock, MJ; Wang, Y; Yu, XM	1
Brooks, G; Harper, J; Li, YQ; Wang, YQ; Wu, XS; Yuan, WZ; Zhu, CB	1
Gelfanova, V; Gonzalez-DeWhitt, PA; Hale, JE; Li, B; Liu, F; May, PC; Ni, B; Paul, SM; Ryder, JW; Su, Y; Wu, X; Zhou, Y	1
Balashov, AM	1
Cui, MZ; Mao, G; Tan, J; Xu, X; Zhao, G	1
Eling, TE; Kim, JI; Moon, Y; Yang, H	1
Baumann, K; Cottrell, BA; Czirr, E; Esselmann, H; Golde, TE; Koo, EH; Kukar, T; Ladd, TB; Leuchtenberger, S; Paul, S; Pietrzik, CU; Schubenel, R; Torpey, JW; Weggen, S; Wiltfang, J	1
Huang, L; Johnson, F; Komninou, D; Mackenzie, G; Ouyang, N; Rigas, B; Sun, Y; Xie, G	1
Cheng, KW; Constantinides, PP; Rigas, B; Wong, CC; Xie, G; Zhou, D; Zhu, CH	1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC	1
Boring, D; Chattopadhyay, M; Dastagirzada, YM; Kashfi, K; Kodela, R; Nath, N; Velázquez-Martínez, CA	1
Cheng, KW; Constantinides, PP; Huang, L; Rigas, B; Wong, CC; Xie, G	1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y	1
Futai, E; Ishiura, S; Watahiki, H; Yagishita, S	1
Cheng, KW; Huang, L; Mattheolabakis, G; Ouyang, N; Papayannis, I; Rigas, B; Wong, CC; Xie, G	1
Gutmann, JL; Jinatongthai, P; Nagendrababu, V; Pulikkotil, SJ; Teerawattanapong, N; Veettil, SK	1
Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B	1

Reviews

8 review(s) available for ibuprofen and sulindac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)]. Terapevticheskii arkhiv, 1978, Volume: 50, Issue:12 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac	1978
Review of ibuprofen for osteoarthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin	1984
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs. East African medical journal, 1982, Volume: 59, Issue:6 Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines	1982
Nonsteroidal antiinflammatory drugs (second of two parts). The New England journal of medicine, 1980, May-29, Volume: 302, Issue:22 Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Propionates; Sulindac; Tolmetin	1980
[Non-steroid anti-inflammatory drugs in the treatment of Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2005, Volume: 105, Issue:9 Topics: Aged; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Indomethacin; Mice; Sulindac	2005
Efficacy and Safety of Oral Premedication on Pain after Nonsurgical Root Canal Treatment: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials. Journal of endodontics, 2019, Volume: 45, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Databases, Bibliographic; Female; Humans; Ibuprofen; Ketorolac; Male; Middle Aged; Pain, Postoperative; Piroxicam; Prednisolone; Premedication; Randomized Controlled Trials as Topic; Root Canal Therapy; Sulindac; Treatment Outcome; Young Adult	2019

Trials

25 trial(s) available for ibuprofen and sulindac

Article	Year
A controlled clinical study comparing sulindac with ibuprofen and aspirin in the treatment of musculo-skeletal diseases. The Journal of international medical research, 1979, Volume: 7, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Back Pain; Clinical Trials as Topic; Female; Humans; Ibuprofen; Indenes; Lumbosacral Region; Male; Middle Aged; Osteoarthritis; Random Allocation; Sulindac; Tenosynovitis	1979
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents. Digestive diseases and sciences, 1979, Volume: 24, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin	1979
A comparison of sulindac with ibuprofen in the management of rheumatoid arthritis. The New Zealand medical journal, 1979, Apr-25, Volume: 89, Issue:634 Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Humans; Ibuprofen; Indenes; Middle Aged; Sulindac	1979
Renal effects of ibuprofen, piroxicam, and sulindac in patients with asymptomatic renal failure. A prospective, randomized, crossover comparison. Annals of internal medicine, 1990, Apr-15, Volume: 112, Issue:8 Topics: Adult; Aged; Creatinine; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Kidney; Kidney Failure, Chronic; Middle Aged; Piroxicam; Prospective Studies; Prostaglandins; Randomized Controlled Trials as Topic; Renal Circulation; Sulindac; Thromboxane B2	1990
Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension. British journal of clinical pharmacology, 1990, Volume: 30, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Chromatography, Affinity; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypertension; Ibuprofen; Kidney; Male; Middle Aged; Sulindac; Thromboxanes	1990
The effect of etodolac administration on renal function in patients with arthritis. Journal of clinical pharmacology, 1986, Volume: 26, Issue:4 Topics: Acetates; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Double-Blind Method; Etodolac; Humans; Ibuprofen; Kidney Function Tests; Middle Aged; Osteoarthritis; Sulindac	1986
Efficacy and safety of nonsteroidal anti-inflammatory drugs in the therapy of diabetic neuropathy. Archives of internal medicine, 1987, Volume: 147, Issue:8 Topics: Aldehyde Reductase; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diabetic Neuropathies; Humans; Ibuprofen; Male; Middle Aged; Sulindac	1987
International experiences with diclofenac in osteoarthritis. The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac	1986
The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide. European journal of clinical pharmacology, 1987, Volume: 31, Issue:5 Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Diclofenac; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Indenes; Male; Middle Aged; Potassium; Renin; Sulindac	1987
Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men. Kidney international, 1985, Volume: 27, Issue:1 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Kidney; Male; Naproxen; Prostaglandins; Random Allocation; Renin; Sulindac; Thromboxanes	1985
Sulindac and ibuprofen inhibit furosemide-stimulated renin release but not natriuresis in men on a normal sodium diet. Nephron, 1985, Volume: 41, Issue:3 Topics: Adult; Chlorides; Diet; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Male; Natriuresis; Potassium; Renin; Sodium; Sulindac; Time Factors	1985
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin. The New England journal of medicine, 1984, Feb-02, Volume: 310, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Chronic Disease; Creatinine; Dinoprostone; Epoprostenol; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Ibuprofen; Indenes; Kidney; Kidney Glomerulus; Middle Aged; p-Aminohippuric Acid; Prostaglandins E; Renal Circulation; Sulindac	1984
Sulindac versus ibuprofen in sprains and strains. British journal of sports medicine, 1984, Volume: 18, Issue:1 Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Humans; Ibuprofen; Indenes; Male; Pain; Random Allocation; Sprains and Strains; Sulindac; Time Factors	1984
Review of ibuprofen for osteoarthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin	1984
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
[Clinical evaluation of sulindac (CLINORIL) in the treatment of acute upper respiratory tract infection--double-blind comparison with ibuprofen]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1983, Volume: 57, Issue:3 Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; Indenes; Male; Middle Aged; Respiratory Tract Infections; Sulindac	1983
Differential efficacy of two non-steroidal anti-inflammatory drugs in the treatment of sports injuries. Current medical research and opinion, 1984, Volume: 9, Issue:2 Topics: Adult; Anti-Inflammatory Agents; Athletic Injuries; Female; Humans; Ibuprofen; Indenes; Male; Pain; Sulindac; Time Factors	1984
Symptomatic osteoarthritis in the elderly: multicentre comparative study of sulindac and ibuprofen. The British journal of clinical practice, 1984, Volume: 38, Issue:5 Topics: Aged; Female; Humans; Ibuprofen; Indenes; Male; Middle Aged; Osteoarthritis; Sulindac	1984
A study of sulindac versus ibuprofen in elderly patients with osteoarthritis. Current medical research and opinion, 1983, Volume: 8, Issue:5 Topics: Aged; Female; Humans; Ibuprofen; Indenes; Male; Osteoarthritis; Sulindac	1983
A randomized comparison between sulindac and ibuprofen in osteoarthritis of the aged. Current medical research and opinion, 1981, Volume: 7, Issue:7 Topics: Aged; Female; Humans; Ibuprofen; Indenes; Male; Osteoarthritis; Random Allocation; Sulindac	1981
Acute and chronic effects of nonsteroidal antiinflammatory drugs on glomerular filtration rate in elderly patients. The American journal of the medical sciences, 1995, Volume: 310, Issue:5 Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Cross-Over Studies; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Inulin; Male; Piroxicam; Renal Insufficiency; Sulindac	1995
Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. The Journal of rheumatology, 1997, Volume: 24, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cross-Over Studies; Electrolytes; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Kidney; Middle Aged; Nabumetone; Prostaglandins; Sulindac; Thromboxane B2	1997
The effect of nonsteroidal antiinflammatory drugs on electrolyte homeostasis and blood pressure in young and elderly persons with and without renal insufficiency. The American journal of the medical sciences, 1997, Volume: 314, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Cross-Over Studies; Humans; Ibuprofen; Natriuresis; Piroxicam; Potassium; Renal Insufficiency; Sulindac	1997
Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs. American journal of hypertension, 1999, Volume: 12, Issue:9 Pt 1 Topics: Acetaminophen; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Butanones; Creatinine; Dinoprostone; Diuretics; Drug Interactions; Drug Therapy, Combination; Female; Fosinopril; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Middle Aged; Nabumetone; Renal Plasma Flow; Sodium; Sodium Chloride Symporter Inhibitors; Sulindac; Thromboxane B2	1999
Effects of non-steroidal anti-inflammatory drugs on hypertension control using angiotensin converting enzyme inhibitors and thiazide diuretics. East African medical journal, 2001, Volume: 78, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Diclofenac; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Lisinopril; Middle Aged; Osteoarthritis; Sulindac; Treatment Outcome	2001

Other Studies

74 other study(ies) available for ibuprofen and sulindac

Article	Year
Novel analgesic-antiinflammatory salicylates. Journal of medicinal chemistry, 1978, Volume: 21, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Dogs; Rats; Salicylates; Structure-Activity Relationship	1978
Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase. Journal of medicinal chemistry, 1990, Volume: 33, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Cyclooxygenase Inhibitors; Hydroxamic Acids; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Meclofenamic Acid	1990
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma). European journal of medicinal chemistry, 2008, Volume: 43, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalytic Domain; Computational Biology; Drug Design; Ligands; Models, Molecular; PPAR gamma; Protein Conformation; Software	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Animals; Cells, Cultured; Child, Preschool; Chimera; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drugs, Investigational; Female; Half-Life; Hepatocytes; Humans; Immunomagnetic Separation; Liver; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Recombinant Proteins; Species Specificity; Urokinase-Type Plasminogen Activator	2012
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Effect of new hybrids based on 5,16-pregnadiene scaffold linked to an anti-inflammatory drug on the growth of a human astrocytoma cell line (U373). European journal of medicinal chemistry, 2015, Mar-26, Volume: 93 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Humans; Molecular Structure; Pregnadienes; Sulindac; Time Factors	2015
Synthesis and Evaluation of Novel Erlotinib-NSAID Conjugates as More Comprehensive Anticancer Agents. ACS medicinal chemistry letters, 2015, Oct-08, Volume: 6, Issue:10 Topics:	2015
Old and new pharmaceutical non-steroidal compounds prescribed for the management of patients with rheumatic diseases. Rheumatology and rehabilitation, 1979, Volume: Suppl Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen; Rheumatic Diseases; Sulindac; Tolmetin	1979
[Sulindac in arthrosis and rheumatoid arthritis]. Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1978, Volume: 5 Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Ibuprofen; Indenes; Joint Diseases; Sulindac	1978
Effect of sulindac on prostaglandin synthesis in human and in cultured rat renal and vascular smooth muscle cells. The Tohoku journal of experimental medicine, 1992, Volume: 166, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Animals; Arachidonic Acids; Cells, Cultured; Creatinine; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Kidney; Kidney Glomerulus; Male; Middle Aged; Muscle, Smooth, Vascular; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulindac	1992
Effects of NSAIDs on NNK-induced pulmonary and gastric tumorigenesis in A/J mice. Cancer letters, 1992, Sep-14, Volume: 66, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcinogens; Drug Interactions; Female; Ibuprofen; Lung Neoplasms; Mice; Mice, Inbred A; Naproxen; Nitrosamines; Piroxicam; Stomach Neoplasms; Sulindac; Time Factors	1992
Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal-sparing effect of sulindac. Gastroenterology, 1986, Volume: 90, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Ibuprofen; Indenes; Kidney; Kidney Function Tests; Liver Cirrhosis, Alcoholic; Middle Aged; Prostaglandins E; Renal Circulation; Sulindac; Thromboxane B2; Time Factors	1986
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs. Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:8 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Dogs; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Microsomes; Phenylbutazone; Prostaglandins; Prostaglandins E; Sulindac	1987
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs. Carcinogenesis, 1986, Volume: 7, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin	1986
Evidence that prostacyclin modulates the vascular actions of calcium in man. The Journal of clinical investigation, 1986, Volume: 77, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Blood Pressure; Calcium; Creatinine; Dinoprostone; Drug Interactions; Epoprostenol; Hemodynamics; Humans; Ibuprofen; Indomethacin; Kidney; Natriuresis; Nifedipine; Potassium; Prazosin; Prostaglandins E; Regional Blood Flow; Sulindac; Vascular Resistance; Vasodilation	1986
Reversible acute decrease in renal function by NSAIDs in cirrhosis. The American journal of the medical sciences, 1987, Volume: 294, Issue:3 Topics: Acute Disease; Creatinine; Female; Humans; Ibuprofen; Indenes; Kidney; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Naproxen; Prostaglandins; Sulindac; Urodynamics	1987
Effects of phenylbutazone and oxyphenbutazone on acidic drug detection in high performance thin layer chromatographic systems. Journal of pharmacological methods, 1986, Volume: 16, Issue:4 Topics: Animals; Chromatography, Thin Layer; Diclofenac; Female; Fenoprofen; Horses; Hydrogen-Ion Concentration; Ibuprofen; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Piroxicam; Sulindac	1986
Role of prostaglandins in the renal handling of a salt load in essential hypertension. The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1 Topics: Adolescent; Adult; Blood Pressure; Cardiac Output; Diuresis; Female; Humans; Hypertension; Ibuprofen; Indomethacin; Kidney; Male; Middle Aged; Potassium; Prostaglandins; Sodium; Sodium Chloride; Sulindac; Vascular Resistance	1985
Effects of the newer nonsteroidal anti-inflammatory agents, ibuprofen, fenoprofen, and sulindac, on neutrophil adherence. The Journal of infectious diseases, 1985, Volume: 152, Issue:4 Topics: Adult; Cell Adhesion; Complement System Proteins; Fenoprofen; Humans; Ibuprofen; In Vitro Techniques; Indenes; Male; Neutrophils; Phenylpropionates; Prostaglandins; Sulindac	1985
Influence of certain prostaglandin synthetase inhibitors on cytoplasmic estrogen receptors in the uterus. American journal of obstetrics and gynecology, 1983, Jan-01, Volume: 145, Issue:1 Topics: Animals; Binding Sites; Cyclooxygenase Inhibitors; Cytoplasm; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sulindac; Time Factors; Uterus	1983
Comparison of the effects of sulindac with other cyclooxygenase inhibitors on prostaglandin excretion and renal function in normal and chronic bile duct-ligated dogs and swine. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:3 Topics: Animals; Bile Ducts; Cyclooxygenase Inhibitors; Dogs; Female; Glomerular Filtration Rate; Ibuprofen; Indenes; Kidney; Ligation; Liver Diseases; Naproxen; Prostaglandins; Sulindac; Swine; Swine, Miniature	1984
[Sulindac in osteoarthrosis]. Harefuah, 1980, Oct-01, Volume: 99, Issue:7 Topics: Adult; Aged; Back Pain; Female; Humans; Ibuprofen; Indenes; Knee Joint; Lumbar Vertebrae; Male; Middle Aged; Osteoarthritis; Sulindac	1980
Pharmacokinetics of ibuprofen. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Adult; Age Factors; Aged; Arthritis, Rheumatoid; Aspirin; Biological Availability; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Interactions; Female; Humans; Ibuprofen; Intestinal Absorption; Kinetics; Liver Diseases, Alcoholic; Male; Milk, Human; Models, Chemical; Sulindac; Time Factors	1984
A clinical evaluation of the antiarthritic agents. Comprehensive therapy, 1984, Volume: 10, Issue:8 Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin	1984
Ibuprofen and sulindac kinetics in alcoholic liver disease. Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:1 Topics: Administration, Oral; Adult; Humans; Ibuprofen; Indenes; Kinetics; Liver Diseases, Alcoholic; Liver Function Tests; Middle Aged; Sulindac	1983
Symptomatic osteoarthritis in the elderly: a comparative study of sulindac and ibuprofen. Current medical research and opinion, 1982, Volume: 7, Issue:Suppl 1 Topics: Aged; Female; Hip Joint; Humans; Ibuprofen; Indenes; Knee Joint; Male; Osteoarthritis; Sulindac	1982
Osteoarthritis and non-steroidal and anti-inflammatory drugs: a multi-centre comparative study. Current medical research and opinion, 1982, Volume: 7, Issue:Suppl 1 Topics: Aged; Diclofenac; Female; Hip Joint; Humans; Ibuprofen; Indenes; Knee Joint; Male; Naproxen; Osteoarthritis; Sulindac	1982
Pharmacotherapy of juvenile rheumatoid arthritis. Pediatric clinics of North America, 1981, Volume: 28, Issue:1 Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Delayed-Action Preparations; Gold; Humans; Ibuprofen; Indomethacin; Penicillamine; Salicylates; Sulindac; Tolmetin	1981
Current review and comparison of the new nonsteroidal anti-inflammatory agents. The Journal of foot surgery, 1980,Winter, Volume: 19, Issue:4 Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Drug Administration Schedule; Fenoprofen; Humans; Ibuprofen; Naproxen; Prostaglandins; Sulindac; Tolmetin	1980
Effects of some nonsteroidal antiinflammatory drugs on proteoglycan metabolism and organization in canine articular cartilage. Arthritis and rheumatism, 1980, Volume: 23, Issue:9 Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Dogs; Fenoprofen; Glycosaminoglycans; Ibuprofen; Indomethacin; Protein Biosynthesis; Proteoglycans; Sulindac	1980
Effects of nonsteroidal antiinflammatory drugs on oxidative pathways in A/J mice. Free radical biology & medicine, 1995, Volume: 18, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Deoxyguanosine; Dinoprostone; DNA; DNA Damage; Female; Ibuprofen; Lipid Peroxidation; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Naproxen; Nitrosamines; Oxidation-Reduction; Oxidative Stress; Piroxicam; Sulindac	1995
Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque. Inflammation, 1996, Volume: 20, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Division; Cell Wall; Child; Dental Plaque; DNA Replication; Duodenum; Edema; Exudates and Transudates; Granuloma; Growth Inhibitors; Humans; Ibuprofen; Indomethacin; Inflammation; Intestinal Mucosa; Naproxen; Rats; Sulindac	1996
Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. Pharmacology & toxicology, 1997, Volume: 80, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Benzoxazines; Calcium Channel Blockers; Cerebellum; Endocannabinoids; Ibuprofen; Kinetics; Membranes; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Radioligand Assay; Rats; Sulindac	1997
Effects of nonsteroidal anti-inflammatory drugs on glutathione S-transferases of the rat digestive tract. Carcinogenesis, 1997, Volume: 18, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cytosol; Digestive System; Dose-Response Relationship, Drug; Enzyme Induction; Esophagus; Glutathione; Glutathione Transferase; Ibuprofen; Indomethacin; Intestines; Isoenzymes; Liver; Male; Organ Specificity; Piroxicam; Rats; Rats, Wistar; Stomach; Substrate Specificity; Sulindac	1997
Immunochemical identification of mouse hepatic protein adducts derived from the nonsteroidal anti-inflammatory drugs diclofenac, sulindac, and ibuprofen. Chemical research in toxicology, 1997, Volume: 10, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Ibuprofen; Immune Sera; Immunoblotting; Immunochemistry; Liver; Mice; Mice, Inbred Strains; Proteins; Rabbits; Sulindac	1997
Nonsteroidal anti-inflammatory drugs enhance glutathione S-transferase theta levels in rat colon. Biochimica et biophysica acta, 1998, Aug-24, Volume: 1381, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colon; Colonic Neoplasms; Diet; Glutathione Transferase; Ibuprofen; Indomethacin; Male; Nabumetone; Piroxicam; Rats; Rats, Wistar; Sulindac	1998
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. The Journal of experimental medicine, 1999, Aug-16, Volume: 190, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Embryo, Mammalian; Fibroblasts; Ibuprofen; Indomethacin; Isoenzymes; Membrane Proteins; Mice; Mice, Knockout; Nitrobenzenes; Oncogene Proteins, Viral; Piroxicam; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Simian virus 40; Sulfonamides; Sulindac	1999
Directed control of electroosmotic flow in nonaqueous electrolytes using poly(ethylene glycol) coated capillaries. Electrophoresis, 2001, Volume: 22, Issue:4 Topics: Acetonitriles; Benzoic Acid; Buffers; Chemical Phenomena; Chemistry, Physical; Electrolytes; Electrophoresis, Capillary; Flurbiprofen; Ibuprofen; Methanol; Osmosis; Phenylacetates; Polyethylene Glycols; Propionates; Reproducibility of Results; Salicylic Acid; Silicon Dioxide; Solvents; Sulindac; Surface Properties; Water	2001
Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention. Cancer research, 2001, Apr-15, Volume: 61, Issue:8 Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Aspirin; Cell Cycle; Cell Division; Colon; Colonic Neoplasms; Growth Inhibitors; HT29 Cells; Humans; Ibuprofen; Nitric Oxide Donors; Sulindac; Tumor Cells, Cultured	2001
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature, 2001, Nov-08, Volume: 414, Issue:6860 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Brain; CHO Cells; Cricetinae; Disease Models, Animal; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Humans; Ibuprofen; Indomethacin; Mass Spectrometry; Mice; Mice, Transgenic; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Sulindac; Tumor Cells, Cultured	2001
[Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2002, Volume: 36, Issue:5 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Female; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Piroxicam; Polyps; Rectal Neoplasms; Risk Factors; Sulindac; Time Factors	2002
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle. The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Cell Division; Cell Line; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Rats; Sodium Salicylate; Sulindac	2003
[Inhibition of vascular smooth muscle cell proliferation by non-steroidal anti-inflammatory drugs]. Shi yan sheng wu xue bao, 2003, Volume: 36, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Cycle; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Muscle, Smooth, Vascular; Rats; Sulindac	2003
Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho. Science (New York, N.Y.), 2003, Nov-14, Volume: 302, Issue:5648 Topics: Amides; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Brain; Cell Line, Tumor; Endopeptidases; Enzyme Inhibitors; Guanosine Triphosphate; Humans; Ibuprofen; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Peptide Fragments; Polyisoprenyl Phosphates; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Sesquiterpenes; Signal Transduction; Sulindac; Transfection	2003
The same gamma-secretase accounts for the multiple intramembrane cleavages of APP. Journal of neurochemistry, 2007, Volume: 100, Issue:5 Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamates; Cell Line, Tumor; Cell Membrane; Dipeptides; Humans; Ibuprofen; Mice; Peptide Fragments; Sulindac	2007
Growth compensatory role of sulindac sulfide-induced thrombospondin-1 linked with ERK1/2 and RhoA GTPase signaling pathways. Life sciences, 2008, Mar-12, Volume: 82, Issue:11-12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation; Humans; Ibuprofen; Indomethacin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; rhoA GTP-Binding Protein; Signal Transduction; Sulindac; Thrombospondin 1	2008
Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase. The Journal of biological chemistry, 2008, Jun-20, Volume: 283, Issue:25 Topics: Amino Acid Sequence; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Humans; Ibuprofen; Molecular Sequence Data; Mutation; Peptide Fragments; Presenilin-1; Sulindac	2008
The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats. British journal of pharmacology, 2011, Volume: 162, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Cell Line; Cytokines; Dinoprostone; Gastrointestinal Diseases; Humans; Ibuprofen; Jurkat Cells; Mice; NF-kappa B; NIH 3T3 Cells; Organophosphates; Organophosphorus Compounds; Rats; Sulindac	2011
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hydrolysis; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Naproxen; Nitrophenols; Organophosphates; Organophosphorus Compounds; Phenylglyoxal; Stomach Neoplasms; Sulindac; Transfection; Valproic Acid; Xenograft Model Antitumor Assays	2012
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs. Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts	2012
Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect. Biochemical pharmacology, 2012, Mar-15, Volume: 83, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Growth Inhibitors; Humans; Hydrogen Sulfide; Ibuprofen; Naproxen; Sulindac; Thiones	2012
Regioselective oxidation of phospho-NSAIDs by human cytochrome P450 and flavin monooxygenase isoforms: implications for their pharmacokinetic properties and safety. British journal of pharmacology, 2012, Volume: 167, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytochrome P-450 Enzyme System; Humans; Ibuprofen; Microsomes, Liver; Models, Biological; Organophosphates; Oxidation-Reduction; Oxygenases; Recombinant Proteins; Sulindac	2012
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. PloS one, 2012, Volume: 7, Issue:8 Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin	2012
CTF1-51, a truncated carboxyl-terminal fragment of amyloid precursor protein, suppresses the effects of Aβ42-lowering γ-secretase modulators. Neuroscience letters, 2012, Sep-27, Volume: 526, Issue:2 Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; CHO Cells; Cricetinae; Cricetulus; Ibuprofen; Peptide Fragments; Sulindac	2012
Phospho-NSAIDs have enhanced efficacy in mice lacking plasma carboxylesterase: implications for their clinical pharmacology. Pharmaceutical research, 2015, Volume: 32, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carboxylic Ester Hydrolases; Carcinoma, Lewis Lung; Ibuprofen; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organophosphates; Organophosphorus Compounds; Sulindac	2015
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs. Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction	2022