ibuprofen has been researched along with ranitidine in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (8.51) | 18.7374 |
1990's | 7 (14.89) | 18.2507 |
2000's | 14 (29.79) | 29.6817 |
2010's | 20 (42.55) | 24.3611 |
2020's | 2 (4.26) | 2.80 |
Authors | Studies |
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Topliss, JG; Yoshida, F | 1 |
Faller, B; Wohnsland, F | 1 |
Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Avdeef, A; Tam, KY | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Akamatsu, M | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Andrys, R; Capek, J; Handl, J; Hrabinova, M; Janockova, J; Kobrlova, T; Korabecny, J; Marco-Contelles, JL; Mezeiova, E; Micankova, P; Muckova, L; Nepovimova, E; Pejchal, J; Rousar, T; Simunkova, M; Soukup, O; Valko, M | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
McGee, BA; Small, RE; Willis, HE; Wilmot-Pater, MG | 1 |
Blocher, CR; Byrne, K; Carey, PD; Hirsh, JI; Sielaff, TD; Sugerman, HJ; Tatum, JL; Vasquez, A | 1 |
Small, RE; Wood, JH | 1 |
Johnson, SM; Karnes, HT; Rajasekharaiah, K; Small, RE; Stephenson, DW; Willis, HE; Wood, JH | 1 |
Bjarnason, I; Levi, AJ; Peters, TJ; Smethurst, P; Williams, P | 1 |
Greenblatt, DJ; Matlis, R; Ochs, HR; Weinbrenner, J | 1 |
Koch, EM; Müller, P; Simon, B | 1 |
King, RL; Levine, RA; Nandi, J; Wagner, KA | 1 |
Berthold, CW; Dionne, RA | 1 |
Jackisch, P; Koch, EM; Müller, P; Simon, B | 1 |
Castro-Gago, M; del Río Pastoriza, I; Fernández Seara, MJ; Martinón Sánchez, JM; Martinón-Torres, F; Rodrigo Sáez, E | 1 |
Aalto-Setälä, V | 1 |
Chiesa, PL; Colangelo, M; Lisi, G | 1 |
Bucuk, M; Crnić-Martinović, M; Perković, O; Poljak, I; Ristić, S; Sepcić, J; Sepcić, K; Sepić-Grahovac, D; Troselj-Vukić, B; Turel, I | 1 |
Mata, JL; Restolho, J; Saramago, B | 1 |
Di, X; Li, W; Liu, FJ; Liu, YD; Xin, GZ; Yao, ZP | 1 |
2 review(s) available for ibuprofen and ranitidine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Congenital chloridorrhea: adjuvant therapy with ibuprofen and ranitidine].
Topics: Antidiarrheals; Chemotherapy, Adjuvant; Chlorides; Diagnosis, Differential; Diarrhea; Facies; Feces; Humans; Ibuprofen; Infant; Male; Ranitidine | 1999 |
3 trial(s) available for ibuprofen and ranitidine
Article | Year |
---|---|
[Protective effects of ranitidine in ibuprofen gastroduodenopathy. An endoscopic controlled double blind study].
Topics: Adolescent; Adult; Double-Blind Method; Endoscopy, Gastrointestinal; Humans; Ibuprofen; Male; Peptic Ulcer; Ranitidine | 1995 |
Clinical evaluation of H1-receptor and H2-receptor antagonists for acute postoperative pain.
Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Molar, Third; Pain, Postoperative; Ranitidine; Terfenadine | 1993 |
[Circadian dependency of ibuprofen gastropathy and the protective effect of ranitidine. An endoscopic, controlled double-blind pilot study].
Topics: Adult; Circadian Rhythm; Double-Blind Method; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Intestinal Mucosa; Pilot Projects; Ranitidine | 1993 |
42 other study(ies) available for ibuprofen and ranitidine
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Drug Design; Humans; Naphthoquinones; Structure-Activity Relationship | 2021 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Effects of misoprostol or ranitidine on ibuprofen pharmacokinetics.
Topics: Adolescent; Adult; Analysis of Variance; Drug Interactions; Female; Humans; Ibuprofen; Male; Misoprostol; Random Allocation; Ranitidine | 1991 |
Ranitidine compared to cimetidine in multiagent pharmacological treatment of porcine Pseudomonas ARDS.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Pseudomonas Infections; Ranitidine; Respiratory Distress Syndrome; Respiratory Function Tests; Shock, Septic; Swine | 1990 |
Influence of racial differences on effects of ranitidine and cimetidine on ibuprofen pharmacokinetics.
Topics: Black People; Cimetidine; Female; Humans; Ibuprofen; Male; Ranitidine; White People | 1989 |
Effect of ranitidine and cimetidine on ibuprofen pharmacokinetics.
Topics: Adult; Cimetidine; Female; Humans; Ibuprofen; Male; Random Allocation; Ranitidine | 1988 |
Effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Humans; Ibuprofen; Indomethacin; Intestine, Small; Permeability; Prostaglandins E; Ranitidine | 1986 |
Interaction of ibuprofen with the H-2 receptor antagonists ranitidine and cimetidine.
Topics: Adult; Analysis of Variance; Biological Availability; Chromatography, High Pressure Liquid; Cimetidine; Drug Interactions; Female; Humans; Ibuprofen; Kinetics; Male; Ranitidine | 1985 |
Effects of nonsteroidal antiinflammatory drugs on ulcerogenesis and gastric secretion in pylorus-ligated rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Ibuprofen; Indomethacin; Ligation; Male; Pepsinogens; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Salicylates; Stomach Ulcer | 1995 |
The impact of generic substitution on price competition in Finland.
Topics: Commerce; Drug Costs; Drug Industry; Drug Prescriptions; Drugs, Generic; Economic Competition; Enalapril; Finland; Ibuprofen; Models, Economic; Ranitidine | 2008 |
Pancreatic inflammatory myofibroblastic tumor (IMT).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Drug Therapy, Combination; Granuloma, Plasma Cell; Histamine H2 Antagonists; Humans; Ibuprofen; Male; Pancreatic Diseases; Ranitidine | 2010 |
Drug-induced aseptic meningitis, sensorineural hearing loss and vestibulopaty.
Topics: Ciprofloxacin; Drug Interactions; Female; Hearing Loss, Sensorineural; Humans; Ibuprofen; Meningitis, Aseptic; Middle Aged; Ranitidine; Tinnitus; Vestibular Neuronitis | 2010 |
Peculiar surface behavior of some ionic liquids based on active pharmaceutical ingredients.
Topics: Dioctyl Sulfosuccinic Acid; Ibuprofen; Ionic Liquids; Lidocaine; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Ranitidine; Surface Tension; Temperature | 2011 |
A novel liquid-liquid-solid microextraction strategy for bio-sample preparation by in situ self-assembly of zeolitic imidazolate framework 8 on hollow fiber membrane.
Topics: Animals; Chromatography, High Pressure Liquid; Ibuprofen; Imidazoles; Limit of Detection; Liquid Phase Microextraction; Membranes, Artificial; Molecular Docking Simulation; Ranitidine; Rats, Sprague-Dawley; Reproducibility of Results; Simvastatin; Solid Phase Microextraction; Tandem Mass Spectrometry; Zeolites | 2020 |