ibuprofen and propranolol

ibuprofen has been researched along with propranolol in 82 studies

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-199012 (14.63)18.7374
1990's6 (7.32)18.2507
2000's23 (28.05)29.6817
2010's37 (45.12)24.3611
2020's4 (4.88)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Caron, G; Ermondi, G1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Akamatsu, M1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Berger, M; Brouhard, BH; Cunningham, RJ; Petrusick, T; Travis, LB1
Boer, P; Dorhout Mees, EJ; Geyskes, GG; Radó, JP; Simatupang, TA; Vos, J1
Tucker, GT1
O'Shaughnessy, CT; Rothwell, NJ; Shrewsbury-Gee, J1
Adi, S; Feingold, KR; Fiers, W; Grunfeld, C; Moser, A; Soued, M1
Sinitsyn, SP1
Cornell, RP1
Bernard, GR; Wright, PE1
Herman, CA; Martinez, JM1
Carlson, EJ; Goldstone, R; Horton, R; Hsueh, WA1
Ishac, EJ; Kunos, G1
Ciancio, SG1
Antman, EM; Lee, TH; Rayment, CM; Salomon, DR1
Maroko, PR1
Grahn, A; Hermansson, J1
Grahn, A; Hermansson, I; Hermansson, J1
Citra, M; Freedman, TB; Long, F; Nafie, LA1
Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M1
Sharma, HS; Winkler, T1
Blomberg, LG; Magnusson, J; Wan, H1
Grishko, VI; Oliveira, D; Tran, CD1
Alnouti, Y; Bi, H; Gusev, AI; Kavetskaia, O; Srinivasan, K; Waddell, D1
Lin, AY; Reinhard, M1
Biebow, M; Boller, M; Pronk, W1
Jones, OA; Lester, JN; Voulvoulis, N1
Heikkinen, AT; Korjamo, T; Mönkkönen, J2
Descamps, M; Klose, D; Siepmann, F; Siepmann, J; Willart, JF1
Ericson, H; Kumblad, L; Thorsén, G1
Alonso, E; Aparicio, I; Camacho-Muñoz, D; Martín, J; Santos, JL1
Constantine, L; Gomez, CF; Huggett, DB1
Korposh, S; Kunitake, T; Lee, SW; Mizutani, N; Selyanchyn, R; Yang, DH1
Douroumis, D; Farrell, T; Levina, M; Nokhodchi, A; Palmer, D; Rajabi-Siahboomi, A1
Eriksson Wiklund, AK; Kumblad, L; Lindh, K; Oskarsson, H1
Danède, F; Delplace, C; Descamps, M; Klose, D; Kreye, F; Siepmann, F; Siepmann, J1
Elliott, M; Etherson, K; Halbert, G2
Alvarez-Lorenzo, C; Burova, TV; Concheiro, A; Dubovik, AS; Grinberg, NV; Grinberg, VY1
Gangopadhyay, AN; Gupta, DK; Pandey, V; Sharma, SP; Tiwari, P1
Darwish, KA; Mrestani, Y; Neubert, RH; Rüttinger, HH1
Daruwalla, V; Saqi, J; Sheraz, F; Tahir, H1
Bury, NR; Chang, ED; Hogstrand, C; Owen, SF; Town, RM1
Kyriacou, A; Mundy-Baird, G; Syed, AA1
Basaran, S; Cikcikoglu Yildirim, N; Serdar, O1

Reviews

4 review(s) available for ibuprofen and propranolol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A clinical pharmacologist's perspective.
    Biochemical Society transactions, 1991, Volume: 19, Issue:2

    Topics: Animals; Humans; Ibuprofen; Pharmacokinetics; Propranolol; Stereoisomerism; Structure-Activity Relationship; Warfarin

1991
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].
    Schmerz (Berlin, Germany), 2002, Volume: 16, Issue:1

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psychology; Child; Flunarizine; GABA Agents; Headache; Humans; Ibuprofen; Metoprolol; Migraine Disorders; Practice Guidelines as Topic; Propranolol; Relaxation Therapy; Serotonin Receptor Agonists; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents

2002

Trials

1 trial(s) available for ibuprofen and propranolol

ArticleYear
Role of propranolol in ulcerated haemangioma of head and neck: a prospective comparative study.
    Oral and maxillofacial surgery, 2016, Volume: 20, Issue:1

    Topics: Acetaminophen; Administration, Oral; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hemangioma; Humans; Ibuprofen; Infant; Male; Pain Measurement; Propranolol; Prospective Studies; Skin Ulcer; Wound Healing

2016

Other Studies

77 other study(ies) available for ibuprofen and propranolol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Long-term use of propranolol, ibuprofen, and spironolactone in the management of Bartter's syndrome.
    Pediatrics, 1979, Volume: 63, Issue:5

    Topics: Adolescent; Bartter Syndrome; Child; Child, Preschool; Drug Therapy, Combination; Growth; Humans; Hyperaldosteronism; Ibuprofen; Male; Potassium; Propranolol; Renin; Spironolactone; Time Factors

1979
Pharmacologic studies in Bartter's syndrome: opposite effects of treatment with antikaliuretic and antiprostaglandin drugs. Part I.
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:1

    Topics: Adult; Amiloride; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Potassium; Propranolol; Prostaglandin Antagonists; Renin; Sodium; Spironolactone; Time Factors

1978
Sympathetically mediated hypermetabolic response to cerebral ischemia in the rat.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:10

    Topics: Adipose Tissue, Brown; Animals; Body Temperature; Brain Ischemia; Cerebral Arteries; Ibuprofen; Male; Oxygen Consumption; Propranolol; Rats; Rats, Inbred Strains; Sympathetic Nervous System

1990
Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6.
    Cancer research, 1990, Jul-15, Volume: 50, Issue:14

    Topics: Animals; Aspirin; Azepines; Cholesterol; Fatty Acids; Ibuprofen; Interleukin-6; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Oleic Acid; Oleic Acids; Pentoxifylline; Phenoxybenzamine; Platelet Activating Factor; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Triazoles; Triglycerides; Tumor Necrosis Factor-alpha

1990
[Correction of metabolic disorders of the myocardium in acute myocardial infarct as an important factor in preventing the development of circulatory insufficiency].
    Kardiologiia, 1985, Volume: 25, Issue:7

    Topics: Animals; Aprotinin; Ascorbic Acid; Drug Therapy, Combination; Glutamates; Glutamic Acid; Heart Failure; Ibuprofen; Myocardial Infarction; Myocardium; Nandrolone; Nandrolone Decanoate; Nifedipine; Potassium Magnesium Aspartate; Propranolol; Rabbits; Sodium Oxybate; Vitamin E

1985
Central interleukin 1-elicited hyperinsulinemia is mediated by prostaglandins but not autonomics.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 2

    Topics: Acetophenones; Adrenocorticotropic Hormone; Animals; Atropine; Autonomic Nervous System; Body Temperature; Cerebral Ventricles; Dinoprostone; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperinsulinism; Ibuprofen; Indomethacin; Injections, Intraventricular; Insulin; Insulin Secretion; Interleukin-1; Male; Meclofenamic Acid; Phentolamine; Propranolol; Propyl Gallate; Rats; Reference Values; SRS-A; Tetrazoles; Vagotomy

1989
Mechanisms of late hemodynamic and airway dynamic responses to endotoxin in awake sheep.
    The American review of respiratory disease, 1989, Volume: 140, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Atropine; Blood Pressure; Endotoxins; Hemodynamics; Ibuprofen; Lung; Lung Compliance; Metaproterenol; Propranolol; Pulmonary Circulation; Pulmonary Gas Exchange; Respiratory Physiological Phenomena; Respiratory System; Sheep; Thromboxane B2

1989
Epinephrine stimulates prostaglandin synthesis by bullfrog lung from warm-acclimated, but not cold-acclimated, animals.
    The Journal of experimental zoology, 1988, Volume: 248, Issue:1

    Topics: Acclimatization; Animals; Cross Reactions; Dose-Response Relationship, Drug; Epinephrine; Fatty Acids; Ibuprofen; Lung; Propranolol; Prostaglandins; Radioimmunoassay; Rana catesbeiana; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Temperature

1988
Evidence that the beta-adrenergic system and prostaglandins stimulate renin release through different mechanisms.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:3

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Ibuprofen; Indomethacin; Infusions, Parenteral; Isoproterenol; Male; Middle Aged; Propranolol; Prostaglandins; Receptors, Adrenergic, beta; Renin

1985
An arachidonate metabolite is involved in the conversion from alpha 1- to beta-adrenergic glycogenolysis in isolated rat liver cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Dactinomycin; Epinephrine; Fatty Acids; Glycogen; Ibuprofen; Isoproterenol; Liver; Male; Masoprocol; Phenylephrine; Phospholipases A; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1986
More commonly prescribed medications.
    Dental management, 1988, Volume: 28, Issue:6

    Topics: Alprazolam; Atenolol; Dental Care; Drug Therapy; Furosemide; Humans; Ibuprofen; Propranolol

1988
Hypotension and sinus arrest with exercise-induced hyperkalemia and combined verapamil/propranolol therapy.
    The American journal of medicine, 1986, Volume: 80, Issue:6

    Topics: Drug Interactions; Heart Arrest; Humans; Hypotension; Ibuprofen; Male; Middle Aged; Physical Exertion; Propranolol; Verapamil

1986
Experimental infarction studies.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:1-2

    Topics: Animals; Chlorpromazine; Dogs; Heart Rate; Ibuprofen; Morphine; Myocardial Infarction; Myocardium; Propranolol; Time Factors; Verapamil

1980
Determination of drugs by direct injection of plasma into a biocompatible extraction column based on a protein-entrapped hydrophobic phase.
    Journal of chromatography. A, 1994, Feb-04, Volume: 660, Issue:1-2

    Topics: Biocompatible Materials; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenytoin; Propranolol; Reproducibility of Results

1994
Direct injection of large volumes of plasma/serum on a new biocompatible extraction column for the determination of atenolol, propranolol and ibuprofen. Mechanisms for the improvement of chromatographic performance.
    Journal of chromatography. A, 1998, Feb-27, Volume: 797, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Analgesics, Non-Narcotic; Atenolol; Biocompatible Materials; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Indicators and Reagents; Propranolol; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet

1998
Hydrogen-stretching vibrational circular dichroism spectroscopy: absolute configuration and solution conformation of selected pharmaceutical molecules.
    Enantiomer, 1999, Volume: 4, Issue:2

    Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Circular Dichroism; Flecainide; Hydrogen; Ibuprofen; Models, Molecular; Molecular Conformation; Molecular Structure; Naphthalenes; Naproxen; Propranolol; Pyrrolidinones; Quinidine; Vibration

1999
Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.
    Muscle & nerve. Supplement, 2002, Volume: 11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Coloring Agents; Cyproheptadine; Dexamethasone; Edema; Electrophysiology; Endothelium; Evans Blue; Evoked Potentials; Fenclonine; Ibuprofen; Indomethacin; Male; Nimodipine; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Cord; Spinal Cord Injuries

2002
Illustration of a simple and versatile scheme for reversing enantiomeric elution order and facilitating enantiomeric impurity determination in capillary electrophoresis.
    Electrophoresis, 2002, Volume: 23, Issue:17

    Topics: Cyclodextrins; Drug Contamination; Electrophoresis, Capillary; Electrophoresis, Gel, Pulsed-Field; Ibuprofen; Propranolol; Reproducibility of Results; Stereoisomerism

2002
Determination of enantiomeric compositions of pharmaceutical products by near-infrared spectrometry.
    Analytical biochemistry, 2004, Feb-15, Volume: 325, Issue:2

    Topics: alpha-Cyclodextrins; Atenolol; Ibuprofen; Isomerism; Pharmaceutical Preparations; Propranolol; Spectroscopy, Near-Infrared; Water

2004
Development and application of a new on-line SPE system combined with LC-MS/MS detection for high throughput direct analysis of pharmaceutical compounds in plasma.
    Journal of chromatography. A, 2005, Jul-08, Volume: 1080, Issue:2

    Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Diclofenac; Ibuprofen; Ketoconazole; Mass Spectrometry; Online Systems; Pharmaceutical Preparations; Propranolol; Reproducibility of Results

2005
Photodegradation of common environmental pharmaceuticals and estrogens in river water.
    Environmental toxicology and chemistry, 2005, Volume: 24, Issue:6

    Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Estrogens; Gemfibrozil; Half-Life; Ibuprofen; Ketoprofen; Naproxen; Oxygen; Pharmaceutical Preparations; Photolysis; Propranolol; Rivers; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical

2005
Electrodialysis for recovering salts from a urine solution containing micropollutants.
    Environmental science & technology, 2006, Apr-01, Volume: 40, Issue:7

    Topics: Carbamazepine; Dialysis; Diclofenac; Electrochemistry; Ibuprofen; Propranolol; Salts; Water Pollutants, Chemical

2006
The occurrence and removal of selected pharmaceutical compounds in a sewage treatment works utilising activated sludge treatment.
    Environmental pollution (Barking, Essex : 1987), 2007, Volume: 145, Issue:3

    Topics: Acetaminophen; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; England; Environmental Pollutants; Gas Chromatography-Mass Spectrometry; Ibuprofen; Mefenamic Acid; Pharmaceutical Preparations; Propranolol; Sewage; Waste Management

2007
Kinetics of cellular retention during Caco-2 permeation experiments: role of lysosomal sequestration and impact on permeability estimates.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3

    Topics: Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cytosol; Humans; Ibuprofen; Kinetics; Lysosomes; Macrolides; Models, Biological; Propranolol; Testosterone

2009
Drug release from PLGA-based microparticles: effects of the "microparticle:bulk fluid" ratio.
    International journal of pharmaceutics, 2010, Jan-04, Volume: 383, Issue:1-2

    Topics: Buffers; Delayed-Action Preparations; Drug Delivery Systems; Hydrogen-Ion Concentration; Ibuprofen; Lactic Acid; Lidocaine; Membrane Fluidity; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propranolol

2010
Determination of permeation resistance distribution in in vitro cell monolayer permeation experiments.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, May-12, Volume: 40, Issue:2

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Caco-2 Cells; Cell Culture Techniques; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Ibuprofen; Metoprolol; Models, Biological; Propranolol

2010
Physiological effects of diclofenac, ibuprofen and propranolol on Baltic Sea blue mussels.
    Aquatic toxicology (Amsterdam, Netherlands), 2010, Aug-15, Volume: 99, Issue:2

    Topics: Animals; Diclofenac; Ibuprofen; Mytilus edulis; Propranolol; Sewage; Water Pollutants, Chemical

2010
Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain).
    Journal of hazardous materials, 2010, Nov-15, Volume: 183, Issue:1-3

    Topics: Environmental Monitoring; Estrogens; Fresh Water; Gemfibrozil; Ibuprofen; Industrial Waste; Naproxen; Pharmaceutical Preparations; Propranolol; Risk Assessment; Rivers; Seasons; Spain; Time Factors

2010
[Update on current care guidelines; childhood headache].
    Duodecim; laaketieteellinen aikakauskirja, 2010, Volume: 126, Issue:14

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Headache; Humans; Ibuprofen; Propranolol; Recurrence; Tryptamines; Vasodilator Agents

2010
The influence of gill and liver metabolism on the predicted bioconcentration of three pharmaceuticals in fish.
    Chemosphere, 2010, Volume: 81, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Contraceptives, Oral, Synthetic; Cytochrome P-450 CYP1A1; Fishes; Gills; Ibuprofen; Ictaluridae; Liver; Norethindrone; Oncorhynchus mykiss; Prescription Drugs; Propranolol; Vasodilator Agents; Water Pollutants, Chemical

2010
Remarkable enantioselectivity of molecularly imprinted TiO2 nano-thin films.
    Analytica chimica acta, 2011, May-23, Volume: 694, Issue:1-2

    Topics: Ibuprofen; Molecular Imprinting; Nanostructures; Naphthols; Propionates; Propranolol; Spectrophotometry, Ultraviolet; Stereoisomerism; Titanium

2011
The influence of sodium carboxymethylcellulose on drug release from polyethylene oxide extended release matrices.
    AAPS PharmSciTech, 2011, Volume: 12, Issue:3

    Topics: Carboxymethylcellulose Sodium; Delayed-Action Preparations; Ibuprofen; Polyethylene Glycols; Propranolol; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Theophylline; Water

2011
Effect studies of human pharmaceuticals on Fucus vesiculosus and Gammarus spp.
    Marine environmental research, 2012, Volume: 74

    Topics: Amphipoda; Animals; Diclofenac; Fucus; Humans; Ibuprofen; Oceans and Seas; Pharmaceutical Preparations; Propranolol; Sewage; Sweden; Water Pollutants, Chemical

2012
Impact of the experimental conditions on drug release from parenteral depot systems: From negligible to significant.
    International journal of pharmaceutics, 2012, Aug-01, Volume: 432, Issue:1-2

    Topics: Dexamethasone; Drug Implants; Ibuprofen; Infusions, Parenteral; Kinetics; Lactic Acid; Lidocaine; Lipids; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prilocaine; Propranolol; Theophylline; X-Ray Diffraction

2012
Determination of excipient based solubility increases using the CheqSol method.
    International journal of pharmaceutics, 2014, Apr-25, Volume: 465, Issue:1-2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Atenolol; Automation, Laboratory; beta-Cyclodextrins; Chemistry, Pharmaceutical; Excipients; Gliclazide; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Pharmaceutical Preparations; Poloxamer; Potentiometry; Propranolol; Solubility; Technology, Pharmaceutical

2014
Binding affinity of thermoresponsive polyelectrolyte hydrogels for charged amphiphilic ligands. A DSC approach.
    Langmuir : the ACS journal of surfaces and colloids, 2014, Apr-15, Volume: 30, Issue:14

    Topics: Binding Sites; Calorimetry, Differential Scanning; Electrolytes; Hydrogels; Ibuprofen; Ligands; Polymers; Propranolol; Surface-Active Agents; Thermodynamics

2014
Drug Release from ß-Cyclodextrin Complexes and Drug Transfer into Model Membranes Studied by Affinity Capillary Electrophoresis.
    Pharmaceutical research, 2016, Volume: 33, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; beta-Cyclodextrins; Cholesterol; Drug Carriers; Drug Liberation; Electrophoresis, Capillary; Ibuprofen; Liposomes; Phospholipids; Propranolol

2016
The influence of non-ionisable excipients on precipitation parameters measured using the CheqSol method.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:9

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Atenolol; beta-Cyclodextrins; Chemistry, Pharmaceutical; Excipients; Gliclazide; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Pharmaceutical Solutions; Poloxamer; Propranolol; Solubility; Solutions

2016
Dengue Fever Presenting Atypically with Viral Conjunctivitis and Subacute Thyroiditis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016, Volume: 26, Issue:6 Suppl

    Topics: Adrenergic beta-Antagonists; Adult; Conjunctivitis, Viral; Dengue; Dengue Virus; Histamine Antagonists; Humans; Ibuprofen; Male; Polymerase Chain Reaction; Propranolol; Thyroiditis, Subacute; Treatment Outcome

2016
Effect of Water pH on the Uptake of Acidic (Ibuprofen) and Basic (Propranolol) Drugs in a Fish Gill Cell Culture Model.
    Environmental science & technology, 2021, 05-18, Volume: 55, Issue:10

    Topics: Animals; Cell Culture Techniques; Gills; Hydrogen-Ion Concentration; Ibuprofen; Pharmaceutical Preparations; Propranolol; Water

2021
De Quervain subacute thyroiditis.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2021, 07-05, Volume: 193, Issue:26

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Diagnosis, Differential; Drug Therapy, Combination; Emergency Service, Hospital; Female; Humans; Ibuprofen; Prednisolone; Propranolol; Thyroiditis, Subacute

2021
The use of
    International journal of environmental health research, 2022, Volume: 32, Issue:11

    Topics: Acetylcholinesterase; Amphipoda; Animals; Antioxidants; Catalase; Ibuprofen; Propranolol; Superoxide Dismutase; Water Pollutants, Chemical

2022