ibuprofen and phenylbutazone

ibuprofen has been researched along with phenylbutazone in 125 studies

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-199081 (64.80)18.7374
1990's17 (13.60)18.2507
2000's13 (10.40)29.6817
2010's12 (9.60)24.3611
2020's2 (1.60)2.80

Authors

AuthorsStudies
Clark, RL; Lanza, T; Pessolano, AA; Risley, EA; Shen, TY; Van Arman, CG; Witzel, B1
Heikes, JE; Sprague, PW1
van Dijk, J; Zwagemakers, JM1
Andrews, PR; Craik, DJ; Martin, JL1
Behn, DC; Botton, I; Fellows, CA; Laskowski, SC; Phillips, DK; Schlegel, DC; Speight, PT; Zenitz, BL1
Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ1
Copeland, RA; Covington, M; Trzaskos, JM; Wilkerson, WW1
Galbraith, W; Gans-Brangs, K; Grubb, M; Hewes, WE; Jaffee, B; Kenney, JP; Kerr, J; Wilkerson, WW; Wong, N1
Inui, KI; Masuda, S; Saito, H1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Inui, K; Saito, H; Uwai, Y1
Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM1
Chang, TK; Ensom, MH; Kiang, TK1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ho, A; Marotti, KR; Romero, DL; Sarver, RW; Thorarensen, A; Tian, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Kumar, M; Sinha, VR; Thareja, S1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Karzel, K; Padberg, DW1
Huskisson, EC1
Akimoto, T; Saito, T; Tachizawa, H; Tsukada, W1
Kawai, K; Kuzuna, S; Morimoto, S1
Nozu, K1
Eberl, R; Fasching, U1
Arrigoni-Martelli, E; Binderup, L; Bramm, E1
Mehta, J; Simchowitz, L; Spilberg, I1
Brewer, EJ1
Brown, KA; Collins, AJ1
Anania, MC; Nencini, P; Paroli, E1
Roe, RL1
Regalado, RG1
Bain, LS; Bruce, GM; Lynch, MP1
Adkinson, NF; Kordansky, D; Norman, PS; Rosenthal, RR1
Burdeĭnyĭ, AP1
Pemberton, RE; Strand, LJ1
Gothoni, G; Rejholec, V; Tokola, O; Vapaatalo, H1
Cioli, V; Corradino, C; Putzolu, S; Rossi, V; Scorza Barcellona, P1
Ohtsuki, H; Okabe, S; Tabata, K1
Sharma, JN1
Birkett, DJ; Myers, SP; Sudlow, G1
Baranova, EIa; Dormidontov, EN; Korshunov, NI1
Brooks, PM1
Kaye, RL; Pemberton, RE1
Rosenthal, SH; Sack, KE1
Grahame, R1
Smiley, JD1
Denman, SJ; Lourie, SH; Schroeder, ET1
Turner, R1
Aparicio, L1
Milazzo, S1
Kitchen, EA; Meacock, SC1
Docken, W; Kantrowitz, FG1
Guyonnet, JC; Julou, L1
Biundo, JJ; Gum, OB; Weiss, TE1
Donovan, JF; Hearron, MS; Levi, L; Moxley, TE; Royer, GL1
McBeath, AA1
Shearman, RP; Smith, ID; Temple, DM1
Denton, JR; Wanwimolruk, S1
Barocelli, E; Bordi, F; Chiavarini, M; Impicciatore, M; Mor, M; Morini, G; Plazzi, PV; Silva, C1
Czernielewski, J; Duteil, L; Ortonne, JP; Poncet, M; Queille, C1
Bernáth, Z; Buzás, G; Hajdu, A; Puscas, I1
Paulus, HE; Schlegel, SI1
Sallmann, AR2
Anderson, WP; Bobik, A1
Crittenden, N; Fitzpatrick, F; McGee, J; McGuire, J1
Fujiyoshi, T; Iida, H; Ikeda, K; Saito, M; Uematsu, T; Yamaura, T1
Zuckner, J1
Blake, JW; Tobin, T; Weckman, T; Woods, WE1
Caulin, C; Dahan, R; Isal, JP; Lagier, G; Simoneau, G1
McGill, PE1
Bagby, GF; O'Brien, WM1
Hudyma, EO; Kollenberg, LO; Robbins, JM1
Melinkeri, RD; Mutalik, GS; Nayak, NJ; Upasani, SP1
Iizuka, Y; Tanaka, K1
Prescott, LF1
Altman, RD1
Bjelle, A; Mjörndal, T1
Alessandrini, A; Gemini, R1
Paradisi, L; Parola, M; Torrielli, MV1
Bhandarkar, SD; Satoskar, RS; Shah, SJ1
Court, H; Volans, GN1
Aihara, H; Amanuma, F; Hashimoto, S; Kameyama, T; Okuyama, S; Orikasa, S; Sakagawa, T; Tarumoto, Y; Tsutsui, Y; Yamada, C1
Diwan, PV; Kulkarni, DR1
Fox, DA; Jick, H1
Obel, AO1
Ciofalo, VB; Diamantis, W; Melton, J; Sofia, RD1
Barabino, A; Corsini, G; Puppo, F; Zavarise, GM1
Zizic, TM1
Dingfelder, JR1
Ghosh, MN; Parmar, NS1
Curzio, M; Negro, F; Paradisi, L; Parola, M; Torrielli, MV1
Fung, WP; Matz, L; Papadimitriou, JM1
Khan, MA; Kushner, I; Schoenberg, LM1
Hüge, W; Stobbe, H1
Aubry, AF; Rahim, S1
Ascoli, G; Bertucci, C; Salvadori, P1
Nakasaka, T; Okabe, N1
Hashizume, N; Okabe, N1
Imai, T; Maruyama, T; Okada, T; Otagiri, M; Rahman, MH1
Becker, L; Eberlein-König, B; Przybilla, B1
Fox, SM; Johnston, SA1
Itoh, T; Saura, Y; Tsuda, Y; Yamada, H1
Kosa, T; Maruyama, T; Otagiri, M1
Kosa, T; Maruyama, T; Otagiri, M; Sakai, N; Yahara, S; Yonemura, N1
Djukovic, D; Henry, I; Liu, S; Raftery, D; Tobias, B1
Gupta, RK; Tandon, VR1
Fehr, J; Gianella, S; Heppner, FL; Kurrer, M; Schaer, DJ; Schwarz, U; Seebach, JD1
Dowling, G; Fabbrocino, S; Gallo, P; Regan, L; Serpe, L1
Eckersten, A; Ellström, C; Fägerstam, L; Gallion, SL; Hogan, JC; Lindquist, C; Pilotti, A; Regberg, T; Shinohara, Y1
Chowdhury, SR; Gokara, M; Narayana, VV; Ramachary, DB; Sadarangani, V; Subramanyam, R; Varkala, S1
Chinthapalli, DK; Nerusu, A; Subramanyam, R1
Glatz, Z; Michalcová, L; Nevídalová, H1
Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B1

Reviews

14 review(s) available for ibuprofen and phenylbutazone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
Antiinflammatory drugs.
    Seminars in arthritis and rheumatism, 1977, Volume: 7, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin

1977
Drug therapy in rheumatic diseases.
    The Medical clinics of North America, 1977, Volume: 61, Issue:2

    Topics: Acetaminophen; Adrenal Cortex Hormones; Antimalarials; Aspirin; Colchicine; Fenoprofen; Gold; Humans; Ibuprofen; Indomethacin; Levamisole; Naproxen; Penicillamine; Phenylbutazone; Rheumatic Diseases; Tolmetin

1977
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:12

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac

1978
Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents.
    Archives of internal medicine, 1976, Volume: 136, Issue:9

    Topics: Activities of Daily Living; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Fenoprofen; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; Oxyphenbutazone; Penicillamine; Phenylbutazone; Physical Therapy Modalities; Tolmetin

1976
Rheumatoid arthritis: an overview.
    Texas medicine, 1976, Volume: 72, Issue:11

    Topics: Adult; Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Aspirin; Diagnosis, Differential; Female; Gold; Humans; Ibuprofen; Indomethacin; Lupus Erythematosus, Systemic; Male; Osteoarthritis; Phenylbutazone; Radiography

1976
Non-steroidal and analgesic therapy in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines

1986
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
    The Journal of rheumatology, 1985, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Colitis; Digestive System; Esophagus; Female; Humans; Ibuprofen; Indomethacin; Liver; Male; Middle Aged; Pancreatitis; Phenylbutazone; Propionates; Sialadenitis

1985
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
    The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1983, Volume: 38, Issue:7

    Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indomethacin; Ketoprofen; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone

1983
Review of ibuprofen for osteoarthritis.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin

1984
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
    East African medical journal, 1982, Volume: 59, Issue:6

    Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines

1982
Primary dysmenorrhea treatment with prostaglandin inhibitors: a review.
    American journal of obstetrics and gynecology, 1981, Aug-15, Volume: 140, Issue:8

    Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Middle Aged; Naproxen; ortho-Aminobenzoates; Phenylbutazone; Prostaglandin Antagonists

1981
Use of carprofen for the treatment of pain and inflammation in dogs.
    Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles

1997

Trials

13 trial(s) available for ibuprofen and phenylbutazone

ArticleYear
[Sulindac: Clinical test of a new antiinflammatory agent in rheumatoid arthritis (author's transl)].
    Wiener klinische Wochenschrift. Supplementum, 1976, Volume: 59

    Topics: Adult; Aged; Alopecia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Clinical Trials as Topic; Drug Eruptions; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Middle Aged; Nausea; Oxyphenbutazone; Phenylbutazone; Vertigo

1976
Butacote and ibuprofen: a comparative assessment in rheumatic diseases in general practice.
    The Journal of international medical research, 1977, Volume: 5 Suppl 2

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Family Practice; Female; Humans; Ibuprofen; Male; Osteoarthritis; Phenylbutazone; Spondylitis, Ankylosing

1977
A double-blind trial of feprazone in osteoarthritis of the hip.
    Current medical research and opinion, 1977, Volume: 4, Issue:9

    Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Feprazone; Hip Joint; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Pain; Phenylbutazone

1977
Asthma improved by nonsteroidal anti-inflammatory drugs.
    Annals of internal medicine, 1978, Volume: 88, Issue:4

    Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forced Expiratory Volume; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Middle Aged; Phenylbutazone; Placebos; Respiratory Function Tests; Sodium Salicylate; Spirometry; Tartrazine

1978
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
    Digestive diseases and sciences, 1979, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin

1979
Tolfenamic acid in the treatment of rheumatoid arthritis.
    Scandinavian journal of rheumatology. Supplement, 1979, Issue:24

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; ortho-Aminobenzoates; Phenylbutazone; Prednisone; Time Factors

1979
Ketoprofen - clinical efficacy.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as Topic; Gout; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Placebos; Sciatica; Spondylitis, Ankylosing

1976
Ibuprofen versus buffered phenylbutazone in the treatment of osteoarthritis: double-blind trial.
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:8

    Topics: Alanine Transaminase; Clinical Trials as Topic; Drug Evaluation; Humans; Ibuprofen; Osteoarthritis; Pain; Phenylbutazone; Placebos; Propionates; Uric Acid

1975
Prevention of non-steroidal anti-inflammatory agents induced acute gastric mucosal lesions by carbonic anhydrase inhibitors. An endoscopic study.
    Acta physiologica Hungarica, 1989, Volume: 73, Issue:2-3

    Topics: Acetazolamide; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Phenylbutazone; Random Allocation; Stomach Ulcer

1989
International experience with diclofenac in rheumatoid arthritis.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone

1986
Evaluation of ibuprofen in the treatment of rheumatoid arthritis assessed by sequential analysis.
    The Journal of the Association of Physicians of India, 1973, Volume: 21, Issue:7

    Topics: Arthritis, Rheumatoid; Double-Blind Method; Hospitalization; Humans; Ibuprofen; Joints; Phenylbutazone

1973
Review of ibuprofen for osteoarthritis.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin

1984
[Comparative clinical study of the efficacy of and tolerance for lysine para-isobutylphenyl propionate in parallel with indomethacin and pyrasanone].
    La Clinica terapeutica, 1980, Jul-31, Volume: 94, Issue:2

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Ibuprofen; Indomethacin; Lysine; Male; Middle Aged; Phenylbutazone; Rheumatic Diseases; Time Factors

1980

Other Studies

99 other study(ies) available for ibuprofen and phenylbutazone

ArticleYear
2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Edema; Gastric Mucosa; Lethal Dose 50; Mice; Pyridines; Rats; Structure-Activity Relationship

1978
Synthesis and antiinflammatory activity of cis-4,5,6,7,8,8a,9-hexahydro-alpha-methyl-5H-fluorene-2-acetic acid.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arthus Reaction; Edema; Fluorenes; Magnetic Resonance Spectroscopy; Molecular Conformation; Rabbits; Rats; Stereoisomerism

1977
Oxime ether derivatives, a new class of nonsteroidal antiinflammatory compounds.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Ethers; Lethal Dose 50; Mice; Oximes; Rats; Structure-Activity Relationship

1977
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Bulky amine analogues of ketoprofen: potent antiinflammatory agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Edema; Indicators and Reagents; Ketoprofen; Magnetic Resonance Spectroscopy; Male; Phenylpropionates; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1984
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemical Phenomena; Chemistry; Imidazoles; Lethal Dose 50; Locomotion; Male; Mice; Muscle Tonus; Nervous System; Orientation; Rats; Structure-Activity Relationship; Thiazoles

1981
Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition.
    Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Pyrroles; Rats; Structure-Activity Relationship

1995
Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR.
    Journal of medicinal chemistry, 1994, Apr-01, Volume: 37, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disease Models, Animal; Drug Tolerance; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1994
Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Drug Interactions; Indomethacin; Ketoprofen; Kidney; Male; Methotrexate; Rats; Rats, Wistar; Tetraethylammonium Compounds

1997
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 1999, Volume: 55, Issue:5

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter.
    European journal of pharmacology, 2000, Dec-01, Volume: 409, Issue:1

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Carrier Proteins; Kinetics; Methotrexate; Oocytes; Probenecid; Uricosuric Agents; Xenopus laevis

2000
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid

2002
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
    Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor.
    Bioorganic & medicinal chemistry letters, 2007, Aug-15, Volume: 17, Issue:16

    Topics: Albumins; Anti-Bacterial Agents; Binding Sites; Calorimetry; Fluorescence; Humans; ortho-Aminobenzoates; Protein Binding

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
[Influence of antirheumatic phenylacetic acid derivatives on glycosaminoglycan metabolism of fibroblast culture (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Bufexamac; Cell Division; Cell Survival; Cells, Cultured; Fibroblasts; Glycosaminoglycans; Ibuprofen; Phenylacetates; Phenylbutazone

1977
Prostaglandin synthetase systems in rat and rabbit renal medulla and inhibition by non-steroidal anti-inflammatory drugs.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Kidney; Kidney Medulla; Male; Microsomes; Phenylbutazone; Prostaglandins E; Prostaglandins F; Rabbits; Rats

1977
Effects of some anti-rheumatic agents on copper-catalyzed thermal aggregation of gamma globulin.
    Agents and actions, 1979, Volume: 9, Issue:4

    Topics: Anti-Inflammatory Agents; Aspirin; Copper; Dexamethasone; Diclofenac; Flufenamic Acid; gamma-Globulins; Gold Sodium Thiomalate; Hot Temperature; Humans; Ibuprofen; Indans; Indomethacin; Penicillamine; Phenylbutazone; Prednisolone

1979
Flurbiprofen: highly potent inhibitor of prostaglandin synthesis.
    Biochimica et biophysica acta, 1978, Jun-23, Volume: 529, Issue:3

    Topics: Animals; Arachidonic Acids; Aspirin; Cattle; Cyclooxygenase Inhibitors; Flurbiprofen; Ibuprofen; Indomethacin; Male; Microsomes; Oxygen Consumption; Phenylbutazone; Propionates; Prostaglandins E; Seminal Vesicles

1978
Characterization of inhibitor(s) of lymphocyte activation in serum from rats with adjuvant arthritis.
    Pharmacology, 1978, Volume: 17, Issue:5

    Topics: Animals; Arthritis; Arthritis, Experimental; Chemical Fractionation; Chromatography, Gel; Concanavalin A; Female; Ibuprofen; Indomethacin; Lymph Nodes; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Penicillamine; Phenylbutazone; Phytohemagglutinins; Rats; Spleen

1978
Chemotactic factor-induced generation of superoxide radicals by human neutrophils: effect of metabolic inhibitors and antiinflammatory drugs.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:7

    Topics: 6-Aminonicotinamide; Anti-Inflammatory Agents; Antimetabolites; Aspirin; Aurothioglucose; Chemotaxis, Leukocyte; Deoxyglucose; Dose-Response Relationship, Drug; Ethylmaleimide; Free Radicals; Glycolysis; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Iodoacetates; Neutrophils; Ouabain; Oxygen; Phenylbutazone; Superoxides

1979
Nonsteroidal antiinflammatory agents.
    Arthritis and rheumatism, 1977, Volume: 20, Issue:2 Suppl

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Humans; Ibuprofen; Indomethacin; Infant; Phenylbutazone; Tolmetin

1977
Action of nonsteroidal, anti-inflammatory drugs on human and rat peripheral leucocyte migration in vitro.
    Annals of the rheumatic diseases, 1977, Volume: 36, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Migration Inhibition; Cell Movement; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Leukocytes; Phenylbutazone; Rats; Sodium Salicylate

1977
Correlations of DNA, RNA and protein levels in duodenal mucosa with antiinflammatory potency and disposition to gut damage of non-steroidal agents. Comparative behaviour of glucametacine, indometacin, phenylbutazone and ibuprofen.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; DNA; Duodenal Ulcer; Duodenum; Female; Gastrointestinal Hemorrhage; Glucosamine; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Phenylbutazone; Proteins; Rats; RNA

1978
The role of direct tissue contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats.
    Toxicology and applied pharmacology, 1979, Sep-15, Volume: 50, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Female; Ibuprofen; Indomethacin; Injections, Intravenous; Male; Peptic Ulcer; Phenylbutazone; Rats

1979
[Irritative activity of a new anti-inflammatory agent 4-(p-chorophenyl)-2-phenyl-5-thiazoleacetic acid (CH-800) on the gastrointestinal tract in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:8

    Topics: Acetates; Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Digestive System; Ibuprofen; Indomethacin; Irritants; Male; Phenylbutazone; Rats; Stomach Ulcer; Thiazoles

1979
Comparison of the anti-inflammatory activity of Commiphora mukul (an indigenous drug) with those of phenylbutazone and ibuprofen in experimental arthritis induced by mycobacterial adjuvant.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Female; Ibuprofen; Male; Mycobacterium; Phenylbutazone; Phenylpropionates; Plant Extracts; Plants, Medicinal; Rabbits; Time Factors

1977
The fatty acid content and drug binding characteristics of commercial albumin preparations.
    Clinica chimica acta; international journal of clinical chemistry, 1978, May-02, Volume: 85, Issue:3

    Topics: Fatty Acids; Fluorescent Dyes; Humans; Ibuprofen; Phenylbutazone; Protein Binding; Sarcosine; Serum Albumin; Spectrometry, Fluorescence

1978
[Antirheumatic non-steroid drugs in the treatment of rheumatoid arthritis].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:9

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Phenylbutazone

1978
Nonsteroidal anti-inflammatory drug treatment for arthritis.
    Australian family physician, 1978, Volume: 7, Issue:8

    Topics: Anti-Inflammatory Agents; Arthritis; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates

1978
Rheumatoid arthritis.
    Postgraduate medicine, 1975, Volume: 58, Issue:5

    Topics: Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Cyclophosphamide; Female; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Ibuprofen; Immunosuppressive Agents; Indomethacin; Middle Aged; Phenylbutazone; Physical Therapy Modalities; Prednisolone; Referral and Consultation

1975
Association of renal papillary necrosis and ankylosing spondylitis.
    Arthritis and rheumatism, 1977, Volume: 20, Issue:4

    Topics: Adult; Humans; Ibuprofen; Indomethacin; Kidney Papillary Necrosis; Male; Phenylbutazone; Spondylitis, Ankylosing

1977
Aspirin and newer anti-inflammatory agents in rheumatoid arthritis.
    American family physician, 1977, Volume: 16, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Peptic Ulcer; Phenylbutazone; Tolmetin

1977
Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 227, Issue:1

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Granulation Tissue; Ibuprofen; Lethal Dose 50; Mice; Phenylbutazone; Phenylbutyrates; Rats; Reaction Time; Stomach Ulcer

1977
The treatment of rheumatoid arthritis.
    Australian family physician, 1977, Volume: 6, Issue:8

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Child; Chloroquine; Female; Gold; Humans; Hydroxychloroquine; Ibuprofen; Indomethacin; Injections, Intra-Articular; Male; Penicillamine; Phenylbutazone; Physical Therapy Modalities; Pregnancy; Pregnancy Complications; Prognosis; Salicylates

1977
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
    Agents and actions, 1976, Volume: 6, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats

1976
Medical management of rheumatoid arthritis.
    Comprehensive therapy, 1976, Volume: 2, Issue:10

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Chloroquine; Gold; Humans; Ibuprofen; Indomethacin; Naproxen; Occupational Therapy; Phenylbutazone; Physical Therapy Modalities

1976
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; Guinea Pigs; Hydroxy Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Ketoprofen; Lung; Muscle Contraction; Naproxen; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Pyrans

1976
Rheumatic diseases. 2. Therapeutic considerations.
    Postgraduate medicine, 1976, Volume: 60, Issue:6

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Calcinosis; Carpal Tunnel Syndrome; Colchicine; Gout; Hip Joint; Humans; Ibuprofen; Indomethacin; Joint Prosthesis; Osteoarthritis; Phenylbutazone; Rheumatic Diseases; Spondylitis, Ankylosing; Tendinopathy

1976
The aging skeleton. Osteoporosis and degenerative arthritis.
    Postgraduate medicine, 1975, Volume: 57, Issue:7

    Topics: Age Factors; Aged; Aspirin; Estrogens; Female; Fracture Fixation; Humans; Ibuprofen; Indomethacin; Joint Prosthesis; Male; Osteoarthritis; Osteoporosis; Phenylbutazone; Sex Factors

1975
The antagonism by anti-inflammatory analgesics of prostaglandin f 2 alpha-induced contractions of human and rabbit myometrium in vitro.
    Prostaglandins, 1975, Volume: 10, Issue:1

    Topics: Abortion, Induced; Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Myometrium; Phenylbutazone; Pregnancy; Pregnancy Trimester, Second; Prostaglandin Antagonists; Prostaglandins F; Rabbits; Stimulation, Chemical; Uterine Contraction; Uterus

1975
Plasma protein binding of quinine: binding to human serum albumin, alpha 1-acid glycoprotein and plasma from patients with malaria.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:10

    Topics: Fluorescence; Humans; Ibuprofen; In Vitro Techniques; Malaria; Orosomucoid; Phenylbutazone; Protein Binding; Quinine; Serum Albumin

1992
4-(1,2-Benzisothiazol-3-yl)alkanoic and phenylalkanoic acids: synthesis and anti-inflammatory, analgesic and antipyretic activities.
    Farmaco (Societa chimica italiana : 1989), 1992, Volume: 47, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Escherichia coli; Ibuprofen; Male; Mice; Pain; Phenylbutazone; Pyrogens; Rats; Rats, Wistar; Thiazoles

1992
Objective assessment of topical corticosteroids and non-steroidal anti-inflammatory drugs in methyl-nicotinate-induced skin inflammation.
    Clinical and experimental dermatology, 1990, Volume: 15, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Bufexamac; Clobetasol; Dermatitis, Contact; Diclofenac; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Male; Nicotinic Acids; Niflumic Acid; Phenylbutazone; Regional Blood Flow; Skin

1990
The history of diclofenac.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Chemical Phenomena; Chemistry; Diclofenac; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazines

1986
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs.
    Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Dogs; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Microsomes; Phenylbutazone; Prostaglandins; Prostaglandins E; Sulindac

1987
Cell damage unmasks 15-lipoxygenase activity in human neutrophils.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: Acetates; Arachidonate Lipoxygenases; Aspirin; Dose-Response Relationship, Drug; Etodolac; Fluorometry; Flurbiprofen; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; L-Lactate Dehydrogenase; Lipoxygenase; Naproxen; Neutrophils; Phenylbutazone

1985
[The analgesic and antipyretic effects of a non-steroidal antiinflammatory agent, EB-382, in experimental animals].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Ibuprofen; Indomethacin; Mice; Morphine; Pain; Phenylbutazone; Propionates; Rats; Rats, Inbred Strains

1986
Effects of phenylbutazone and oxyphenbutazone on acidic drug detection in high performance thin layer chromatographic systems.
    Journal of pharmacological methods, 1986, Volume: 16, Issue:4

    Topics: Animals; Chromatography, Thin Layer; Diclofenac; Female; Fenoprofen; Horses; Hydrogen-Ion Concentration; Ibuprofen; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Piroxicam; Sulindac

1986
[Gastric potential difference: effects of non-steroidal anti-inflammatory agents in the healthy volunteer].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:12 Pt 2

    Topics: Action Potentials; Adolescent; Adult; Anti-Inflammatory Agents; Female; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Male; Phenylbutazone; Phenylpropionates

1985
NSAID-plasma concentration monitoring--optimizing treatment of R.A.
    Agents and actions. Supplements, 1985, Volume: 17

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Kinetics; Metabolic Clearance Rate; Naproxen; Phenylacetates; Phenylbutazone

1985
The history of diclofenac.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1

    Topics: Diclofenac; History, 20th Century; Ibuprofen; Ketoprofen; Models, Molecular; Naproxen; Phenylbutazone; Piroxicam; Solubility; Structure-Activity Relationship; Thiazines

1985
Nonsteroidal anti-inflammatory agents. A review of the literature.
    Journal of the American Podiatric Medical Association, 1985, Volume: 75, Issue:10

    Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Half-Life; Humans; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Naproxen; Phenylbutazone; Piroxicam; Pregnancy; Thiazines; Tolmetin

1985
][A new method for screening of analgesics applied to heat induced inflammatory pain].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:5

    Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Habituation, Psychophysiologic; Hot Temperature; Ibuprofen; Indomethacin; Inflammation; Mefenamic Acid; Phenylbutazone; Pyrroles; Rats

1974
Clinical features and management of analgesic poisoning.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Acetaminophen; Acetylcysteine; Analgesics; Analgesics, Opioid; Humans; Ibuprofen; Mefenamic Acid; Phenylbutazone; Salicylates

1984
Drug prescription patterns for rheumatic disorders in Sweden.
    The Journal of rheumatology, 1984, Volume: 11, Issue:4

    Topics: Administration, Oral; Anti-Inflammatory Agents; Chloroquine; Drug Prescriptions; Drug Utilization; Gold Sodium Thiomalate; Hospitals, University; Humans; Ibuprofen; Indomethacin; Naproxen; Penicillamine; Pharmacy Service, Hospital; Phenylbutazone; Rheumatic Diseases; Rheumatology; Suppositories; Sweden

1984
Non-steroidal anti-inflammatory agents and hepatic lipid peroxidation in normal- and carrageenin-treated rats.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 45, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride Poisoning; Carrageenan; Glutathione; Ibuprofen; Indomethacin; Lipid Peroxides; Liver; Male; Phenylbutazone; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet

1984
Drug interaction between chlorpropamide and non-steroidal anti-inflammatory drugs, ibuprofen and phenylbutazone.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:9

    Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Interactions; Humans; Ibuprofen; Middle Aged; Phenylbutazone; Random Allocation

1984
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
    Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin

1984
[The analgesic and antipyretic effects of a non-steroidal anti-inflammatory drug, oxaprozin, in experimental animals].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Dogs; Ibuprofen; Indomethacin; Male; Mice; Oxaprozin; Phenylbutazone; Propionates; Rats

1984
Influence of non-steroidal anti-inflammatory agents on tolbutamide hypoglycaemia.
    The Indian journal of medical research, 1983, Volume: 78

    Topics: Animals; Anti-Inflammatory Agents; Female; Humans; Hypoglycemia; Ibuprofen; Indomethacin; Male; ortho-Aminobenzoates; Phenylbutazone; Rabbits; Tolbutamide

1983
Nonsteroidal anti-inflammatory drugs and renal disease.
    JAMA, 1984, Mar-09, Volume: 251, Issue:10

    Topics: Anti-Inflammatory Agents; Blood Urea Nitrogen; Depression, Chemical; Humans; Ibuprofen; Indomethacin; Kidney; Phenylbutazone; Prostaglandins E; Renal Circulation

1984
Comparative gastric ulcerogenic effects of meseclazone, 5-chlorosalicylic acid and other nonsteroidal anti-inflammatory drugs following acute and repeated oral administration to rats.
    Toxicology and applied pharmacology, 1980, Mar-15, Volume: 52, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Biotransformation; Fenoprofen; Ibuprofen; Indomethacin; Male; Naproxen; Oxazines; Peptic Ulcer Hemorrhage; Phenylbutazone; Rats; Salicylates; Stomach Ulcer; Time Factors; Tolmetin

1980
[Evaluation of the effect of ibuprofen lysinate on lymphocytic transformation in vitro. Comparison with meglumine indomethacinate, phenylbutazone, and lysine acetylsalicylate].
    Il Farmaco; edizione pratica, 1980, Volume: 35, Issue:4

    Topics: Anti-Inflammatory Agents; Aspirin; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Lysine; Meglumine; Phenylbutazone

1980
Rheumatoid arthritis IV: non-steroidal anti-inflammatory agents use in treatment.
    Maryland state medical journal, 1982, Volume: 31, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Tolmetin

1982
Gastric anti-ulcer activity of (+)-cyanidanol-3, a histidine decarboxylase inhibitor.
    European journal of pharmacology, 1981, Jan-05, Volume: 69, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Benzopyrans; Carboxy-Lyases; Catechin; Female; Gastric Acidity Determination; Gastric Mucosa; Histidine Decarboxylase; Ibuprofen; Male; Phenylbutazone; Rats; Reserpine; Restraint, Physical; Stomach Ulcer

1981
[Lipid peroxidation in the rat liver after acute inflammation induced by carrageenan. I. Influence of non-steroidal anti-inflammatory agents].
    Bollettino della Societa italiana di biologia sperimentale, 1981, Mar-30, Volume: 57, Issue:6

    Topics: Animals; Carbon Tetrachloride; Carrageenan; Edema; Ibuprofen; Indomethacin; Inflammation; Lipid Peroxides; Liver; Male; Phenylbutazone; Rats; Rats, Inbred Strains

1981
Effective of acetylsalicylic acid, indomethacin, phenylbutazone, paracetamol, ibuprofen and naproxen on canine gastric mucosa: a histological and ultrastructural study.
    Annals of the Academy of Medicine, Singapore, 1981, Volume: 10, Issue:3

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Gastric Mucosa; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone

1981
Concanavalin A-induced transformation of mononuclear cells: influence of plasma from patients receiving anti-inflammatory agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 164, Issue:2

    Topics: Bone Diseases; Cells, Cultured; Concanavalin A; Culture Media; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Phenylbutazone; Plasma; Prostaglandins

1980
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Dec-01, Volume: 35, Issue:23

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Penicillamine; Phenylbutazone; Thrombocytopenia

1980
Location of binding sites on immobilized human serum albumin for some nonsteroidal anti-inflammatory drugs.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin; Warfarin

1995
Stereospecific and competitive binding of drugs to human serum albumin: a difference circular dichroism approach.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:6

    Topics: Binding, Competitive; Circular Dichroism; Diazepam; Humans; Ibuprofen; Ligands; Phenylbutazone; Protein Binding; Salicylates; Serum Albumin; Stereoisomerism

1995
Drug binding properties of glycosylated bovine serum albumin as measured by circular dichroism.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:11

    Topics: Binding Sites; Circular Dichroism; Flufenamic Acid; Glycosylation; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin, Bovine; Warfarin

1994
Drug binding properties of glycosylated human serum albumin as measured by fluorescence and circular dichroism.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1

    Topics: Binding Sites; Circular Dichroism; Dansyl Compounds; Flufenamic Acid; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Ibuprofen; Phenylbutazone; Proline; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin

1994
Study of interaction of carprofen and its enantiomers with human serum albumin--II. Stereoselective site-to-site displacement of carprofen by ibuprofen.
    Biochemical pharmacology, 1993, Nov-17, Volume: 46, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Carbazoles; Circular Dichroism; Dialysis; Humans; Ibuprofen; Mathematics; Models, Chemical; Phenylbutazone; Serum Albumin; Stereoisomerism; Warfarin

1993
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocytes; Hemolysis; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Light; Naproxen; Phenylbutazone; Photosensitizing Agents; Piroxicam; Propionates

1996
Stereoselectivity and enantiomer-enantiomer interactions in the binding of ibuprofen to human serum albumin.
    Chirality, 1997, Volume: 9, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Diazepam; Digitoxin; Fluorescent Dyes; Humans; Ibuprofen; In Vitro Techniques; Kinetics; Ligands; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism

1997
Species differences of serum albumins: I. Drug binding sites.
    Pharmaceutical research, 1997, Volume: 14, Issue:11

    Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Humans; Ibuprofen; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Rabbits; Rats; Serum Albumin; Warfarin

1997
Species differences of serum albumins: III. Analysis of structural characteristics and ligand binding properties during N-B transitions.
    Pharmaceutical research, 1998, Volume: 15, Issue:4

    Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ligands; Phenylbutazone; Protein Conformation; Rabbits; Rats; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Warfarin

1998
Signal enhancement in HPLC/microcoil NMR using automated column trapping.
    Analytical chemistry, 2006, Oct-15, Volume: 78, Issue:20

    Topics: Chromatography, High Pressure Liquid; Ibuprofen; Magnetic Resonance Spectroscopy; Naproxen; Phenylbutazone

2006
Vitex negundo Linn (VN) leaf extract as an adjuvant therapy to standard anti-inflammatory drugs.
    The Indian journal of medical research, 2006, Volume: 124, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Edema; Female; Granuloma; Ibuprofen; Male; Phenylbutazone; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Vitex

2006
Retinal microangiopathy and rapidly fatal cerebral edema in a patient with adult-onset Still's disease and concurrent macrophage activation syndrome.
    American journal of hematology, 2008, Volume: 83, Issue:5

    Topics: Adult; Brain Edema; Confusion; Drug Therapy, Combination; Early Diagnosis; Etanercept; Fatal Outcome; Female; Humans; Ibuprofen; Immunoglobulin G; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation; Magnetic Resonance Imaging; Methylprednisolone; Phenylbutazone; Receptors, Tumor Necrosis Factor; Retinal Diseases; Retinal Vessels; Still's Disease, Adult-Onset

2008
Determination of ibuprofen, ketoprofen, diclofenac and phenylbutazone in bovine milk by gas chromatography-tandem mass spectrometry.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2008, Volume: 25, Issue:12

    Topics: Animals; Cattle; Diclofenac; Drug Residues; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Milk; Phenylbutazone; Sensitivity and Specificity; Tandem Mass Spectrometry

2008
Novel affinity ligands for chromatography using combinatorial chemistry.
    Combinatorial chemistry & high throughput screening, 2011, Volume: 14, Issue:4

    Topics: Binding Sites; Binding, Competitive; Chromatography, Affinity; Combinatorial Chemistry Techniques; Cross-Linking Reagents; High-Throughput Screening Assays; Humans; Ibuprofen; Kinetics; Ligands; Oxazolone; Phenylbutazone; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Surface Plasmon Resonance

2011
Unravelling the binding mechanism and protein stability of human serum albumin while interacting with nefopam analogues: a biophysical and insilico approach.
    Journal of biomolecular structure & dynamics, 2017, Volume: 35, Issue:10

    Topics: Analgesics, Non-Narcotic; Binding Sites; Binding, Competitive; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Kinetics; Lidocaine; Molecular Docking Simulation; Molecular Dynamics Simulation; Nefopam; Phenylbutazone; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Stability; Serum Albumin, Human; Solutions; Thermodynamics

2017
Role of Herborn (K240E) and Milano Slow (D375H) human serum albumin variants towards binding of phenylbutazone and ibuprofen.
    International journal of biological macromolecules, 2019, Aug-01, Volume: 134

    Topics: Alleles; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Circular Dichroism; Fluorescent Antibody Technique; Humans; Ibuprofen; Mutagenesis, Site-Directed; Mutant Proteins; Phenylbutazone; Protein Binding; Protein Conformation, alpha-Helical; Recombinant Proteins; Serum Albumin, Human; Spectrometry, Fluorescence; Structure-Activity Relationship

2019
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
    Journal of separation science, 2020, Volume: 43, Issue:22

    Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan

2020
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs.
    Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction

2022